iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ani-009383

Ensembl Protein ID

CADANIAP00006625

UniProt Accession

Q00659; C8V0Y0; Q5AZC1; SCONB_EMENI

Genbank Protein ID

AAC15905.1; EAA58743.1; CBF69629.1

Protein Name

Probable E3 ubiquitin ligase complex SCF subunit sconB; Sulfur controller B; Sulfur metabolite repression control protein B

Genbank Nucleotide ID

U21220; AACD01000107; BN001301

Gene Name

ANIA_06359; sconB; mapB1; AN6359

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADANIAG00006625	CADANIAT00006625	CADANIAP00006625

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.10e-56	182.6	387	423
UBD/Beta-Prp	9.80e-78	260.4	342	677

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvllk 37
           gH+++++cl+f+dt l+sGs D tikvW++rtg ++ 
   Q: 387  GHESGIRCLQFDDTKLISGSMDRTIKVWNWRTGECIS 423
           8**********66*********************975 PP

UBD/Beta-Prp

   S: 2    iktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghe 94
           ikt+kgh  +v++ ++f  ++++latgs+d tik+wd++tg  lr+l ghe+++++++f+++   l++gs Drtikvw+ +tg+c++t++gh 
   Q: 342  IKTFKGHTNGVMC-LQF--EDNILATGSYDTTIKIWDTETGEELRTLRGHESGIRCLQFDDT--KLISGSMDRTIKVWNWRTGECISTYTGHR 429
           7899999999999.***..*******************************************..6**************************** PP
   S: 95   dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysls 187
             v  l+f++  + l+sGs d+t+++w+ e ++ ++  l+gh+++vn v+v+ +++ ++s+s+D tvrlWdl t++++rt+ g h ++v+ + 
   Q: 430  GGVIGLHFDA--SILASGSVDKTVKIWNFEDKSTFS--LRGHTDWVNAVRVDTSSRTVFSASDDCTVRLWDLDTKTCIRTFHG-HVGQVQQVV 517
           **********..***********************7..********************************************9.********* PP
   S: 188  ................fdsng............................................kelvsgsldgtvklwdlqtgecvrtlng 220
                                                                            +++v+ +ld+t++lw+  tg+c+rt+ g
   Q: 518  plprefefeehdaeceN---DdlsttsgdadppsiqasmglepnaaysqssafgtsfdngraappRYMVTSALDSTIRLWETTTGRCLRTFFG 607
           99999886665555550...0555566677777777777888888888888999999999********************************* PP
   S: 221  htdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklk 295
           h + v+ + ++  + r+vsg++D+ i+iWd r+g++ +t+++h     +v+++++gd+ +++gsed++v++++++
   Q: 608  HLEGVWALGAD--TLRIVSGAEDRMIKIWDPRTGKCERTFTGHS---GPVTCIGLGDSRFATGSEDCEVRMYSFQ 677
           ******88888..*****************************88...55555666*****************996 PP

Organism

Aspergillus nidulans

Functional Description
(View)

Component of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.

Protein Sequence
(Fasta)

MSTEDNHDSQ ILTARHRSDA SEQSFKSLFG GPSSEDGKET EPDTHDHNHS FSNAKAPAKF 60
ANQNVAPFLA RHIPEQYAPL GAQSILPADL SSANSKYCYR HRPDQKCRRQ ADEPSMDKLQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCACCTTTCT TTATCTTACA CCGCATATCC AGCCCACAGA GTGATAAATC CGTCCGATTC 60
TGATCCCATA CCTCGAACCA TTGTTCAGCG CTTCGCTCCT TGTTCGTCTT CGGTCACTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0043224--C:nuclear SCF ubiquitin ligase complex
GO:0071276--P:cellular response to cadmium ion
GO:0006270--P:DNA replication initiation
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030174--P:regulation of DNA-dependent DNA replication initiation
GO:0000083--P:regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0046685--P:response to arsenic-containing substance
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0006351--P:transcription, DNA-templated

KEGG

ani:AN6359.2

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007794	Ashbya gossypii	42.91	2.00e-136	477.00
IUUC-Acl-008078	Aspergillus clavatus	78.21	0.00e+00	1095.00
IUUC-Afl-008744	Aspergillus flavus	81.89	0.00e+00	1048.00
IUUC-Afu-008939	Aspergillus fumigatus	76.66	0.00e+00	1066.00
IUUC-Ang-009570	Aspergillus niger	80.77	0.00e+00	1075.00
IUUC-Aor-010217	Aspergillus oryzae	81.48	0.00e+00	1037.00
IUUC-Ate-010336	Aspergillus terreus	81.51	0.00e+00	1073.00
IUUC-Bgr-012225	Blumeria graminis	58.25	0.00e+00	750.00
IUUC-Bci-013916	Botrytis cinerea	64.55	0.00e+00	840.00
IUUC-Cgl-026550	Colletotrichum gloeosporioides	49.11	3.00e-176	610.00
IUUC-Cne-026800	Cryptococcus neoformans	35.16	1.00e-123	436.00
IUUC-Dse-031413	Dothistroma septosporum	56.31	0.00e+00	725.00
IUUC-Fox-037683	Fusarium oxysporum	52.41	0.00e+00	665.00
IUUC-Fso-038092	Fusarium solani	58.39	0.00e+00	757.00
IUUC-Ggr-039842	Gaeumannomyces graminis	54.42	0.00e+00	712.00
IUUC-Kpa-049101	Komagataella pastoris	46.45	4.00e-166	576.00
IUUC-Lma-053200	Leptosphaeria maculans	56.05	0.00e+00	756.00
IUUC-Mor-057039	Magnaporthe oryzae	55.35	0.00e+00	695.00
IUUC-Mpo-057381	Magnaporthe poae	54.27	0.00e+00	698.00
IUUC-Mla-059099	Melampsora laricipopulina	39.74	1.00e-122	432.00
IUUC-Mvi-060426	Microbotryum violaceum	40.59	6.00e-55	207.00
IUUC-Nfi-068464	Neosartorya fischeri	75.90	0.00e+00	1048.00
IUUC-Ncr-068962	Neurospora crassa	51.99	0.00e+00	676.00
IUUC-Pno-095133	Phaeosphaeria nodorum	53.47	5.00e-158	549.00
IUUC-Pgr-103527	Puccinia graminis	41.62	6.00e-67	246.00
IUUC-Ptt-103819	Puccinia triticina	34.31	1.00e-55	209.00
IUUC-Pte-104035	Pyrenophora teres	56.85	0.00e+00	694.00
IUUC-Pyt-104799	Pyrenophora triticirepentis	56.54	0.00e+00	701.00
IUUC-Sce-106343	Saccharomyces cerevisiae	41.44	2.00e-139	487.00
IUUC-Sja-107945	Schizosaccharomyces japonicus	39.34	1.00e-121	428.00
IUUC-Spo-108115	Schizosaccharomyces pombe	40.34	1.00e-127	448.00
IUUC-Sre-115173	Sporisorium reilianum	40.80	2.00e-105	375.00
IUUC-Tre-122126	Trichoderma reesei	57.86	0.00e+00	751.00
IUUC-Tvi-122482	Trichoderma virens	58.29	0.00e+00	760.00
IUUC-Tme-127212	Tuber melanosporum	54.77	0.00e+00	745.00
IUUC-Uma-129406	Ustilago maydis	47.06	7.00e-64	237.00
IUUC-Vda-129799	Verticillium dahliae	56.34	0.00e+00	714.00
IUUC-Yli-134408	Yarrowia lipolytica	46.75	1.00e-169	588.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence