iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033881

UUCD1 version

UUC-EqC-00094

Ensembl Protein ID

ENSECAP00000022843.1

UniProt Accession

F6R1E6; F6R1E6_HORSE

Protein Name

Uncharacterized protein

Gene Name

EDA2R

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000026956.1	ENSECAT00000028930.1	ENSECAP00000022843.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/APC_C/APC_C	32.65	5.50e-01	30.00	IUUC-Sce-106433

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Equus caballus

Protein Sequence
(Fasta)

DCQENEYWDQ WGHCTCQLCG SGQELSKDCG YGEGGDAYLI ALPAHRKSSW GHHRCQTCIT 60
CAVINHVLKV NCTATSNAVC GDCVSRFHQK TCIGGLQDQG CIPCMKQIPT SEVQCAFLLS 120

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Nucleotide Sequence
(Fasta)

GATTGCCAAG AAAATGAGTA CTGGGACCAA TGGGGACACT GTCACCTGCC AACTGTGTGG 60
GTCTGGACAA GAACTCTCCA AGGTAAGTCT CTTGGTCAGG ATACTTATTT CTGTTACATC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001368--TNFR/NGFR_Cys_rich_reg
IPR022319--TNFR_27

Pfam

PF00020--TNFR_c6

PRINTS

PR01973--TNFACTORR27

SMART

SM00208--TNFR

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0005622--C:intracellular
GO:0005886--C:plasma membrane
GO:0004872--F:receptor activity
GO:0072332--P:intrinsic apoptotic signaling pathway by p53 class mediator
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046330--P:positive regulation of JNK cascade
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0009888--P:tissue development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Itr-048526	Ictidomys tridecemlineatus	36.59	1.00e-04	40.40
IUUC-Sce-106433	Saccharomyces cerevisiae	32.65	2.60e-01	29.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence