iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088245

Ensembl Protein ID

ENSOGAP00000003191.2

UniProt Accession

H0WN24; H0WN24_OTOGA

Genbank Protein ID

ENSOGAP00000003191

Protein Name

Fibroblast growth factor

Genbank Nucleotide ID

AAQR03172831

Gene Name

FGF21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000003581.2	ENSOGAT00000003585.2	ENSOGAP00000003191.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_Other	48.28	3.70e-02	33.10	IUUC-Sce-106452

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MGWDKARTGF KHPGPWFPLL AVLLLGACQA HPIPDSSPLL QFGGQVRQRY LYTDDAQETE 60
AHLEIREDGT VVGAAQQSPE SLLELKALKP GVIQILGVKT SRFLCQRPDG GLYGSLYFDP 120

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Nucleotide Sequence
(Fasta)

ATGGGCTGGG ACAAGGCCAG GACTGGGTTC AAGCACCCAG GACCATGGTT TCCCCTGCTG 60
GCTGTACTTT TGTTGGGAGC CTGCCAGGCA CACCCTATCC CTGACTCCAG CCCCCTACTC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0339--Growth factor
KW-1185--Reference proteome
KW-0732--Signal

Interpro

IPR028292--FGF21
IPR002209--Fibroblast_GF_fam
IPR008996--IL1/FGF

PROSITE

PS00247--HBGF_FGF

Pfam

PF00167--FGF

PRINTS

PR00263--HBGFFGF

SMART

SM00442--FGF

Gene Ontology

GO:0005576--C:extracellular region
GO:0008284--P:positive regulation of cell proliferation
GO:0070374--P:positive regulation of ERK1 and ERK2 cascade
GO:0046326--P:positive regulation of glucose import
GO:0090080--P:positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Rno-105302	Rattus norvegicus	72.17	1.00e-75	275.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence