iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Rno-105302

Ensembl Protein ID

ENSRNOP00000028490.1

UniProt Accession

Q8VI80; Q8VI80_RAT

Genbank Protein ID

BAB84299.1; EDM07326.1

Protein Name

Fibroblast growth factor

Genbank Nucleotide ID

AABR07003259; CH473979

Gene Name

Fgf21; FGF21; rCG_54320

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000020990.2	ENSRNOT00000028490.2	ENSRNOP00000028490.1

Annotation

mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_Other	41.03	4.50e-02	32.70	IUUC-Sce-106452

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MDWMKSRVGA PGLWVCLLLP VFLLGVCEAY PISDSSPLLQ FGGQVRQRYL YTDDDQDTEA 60
HLEIREDGTV VGTAHRSPES LLELKALKPG VIQILGVKAS RFLCQQPDGT LYGSPHFDPE 120

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Nucleotide Sequence
(Fasta)

ATGGACTGGA TGAAATCTAG AGTTGGGGCC CCGGGACTGT GGGTCTGTCT CCTGCTGCCT 60
GTCTTCCTGC TGGGGGTGTG CGAGGCATAC CCCATCTCTG ACTCCAGCCC CCTCCTCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0339--Growth factor
KW-1185--Reference proteome
KW-0732--Signal

Interpro

IPR028292--FGF21
IPR002209--Fibroblast_GF_fam
IPR008996--IL1/FGF

PROSITE

PS00247--HBGF_FGF

Pfam

PF00167--FGF

PRINTS

PR00263--HBGFFGF

SMART

SM00442--FGF

Gene Ontology

GO:0005615--C:extracellular space
GO:0035690--P:cellular response to drug
GO:0071377--P:cellular response to glucagon stimulus
GO:0071333--P:cellular response to glucose stimulus
GO:0071404--P:cellular response to low-density lipoprotein particle stimulus
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0072577--P:endothelial cell apoptotic process
GO:2000352--P:negative regulation of endothelial cell apoptotic process
GO:1901215--P:negative regulation of neuron death
GO:0008284--P:positive regulation of cell proliferation
GO:0070374--P:positive regulation of ERK1 and ERK2 cascade
GO:0046326--P:positive regulation of glucose import
GO:0090080--P:positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
GO:0010898--P:positive regulation of triglyceride catabolic process
GO:0014823--P:response to activity
GO:1904640--P:response to methionine
GO:0031667--P:response to nutrient levels

KEGG

rno:170580

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Oga-088245	Otolemur garnettii	73.58	3.00e-80	290.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence