iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Post-translational Modifications (PTMs)
dbPPT	dbPTM	UniProt
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.10e-11	43.6	235	269

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrt 32
           gH+ +vt++af   d ++l+s s Dg++ vW +++
   Q: 235  GHSQRVTDMAFfaEDvDMLASVSLDGKVFVWKISE 269
           8*********999888***************9765 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

As a component of the decapping complex, involved in the degradation of mRNAs. Essential for postembryonic development, especially during the formation of the shoot (SAM) and root apical meristems. Required for normal patterning of internal tissues of leaves.

Protein Sequence
(Fasta)

MASSPGNTNP HNTPPFDLGI LFKPSSNPYP PPAASYPPPT GPFLHNQYDQ QHYAPPGISA 60
QPSPVTQQQQ DVSSSSAATN LHPQRTLSYP TPPLNLQSPR SNHNPGTHIL ALLNNTNNGA 120

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Nucleotide Sequence
(Fasta)

CCCAATTTAA TATTTTCATT AAAGAAGAAG AAAAAATAGC TAAGTCTCCA AAAGTTCTCT 60
ACCTGTTCTC ACTTTCAAGT CATCATCGTC TCTCTCTCTC TATTGTTGCT CTCTCTCTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0507--mRNA processing
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR032401--EDC4_WD40
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF16529--Ge1_WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0000932--C:P-body
GO:0003729--F:mRNA binding
GO:0071365--P:cellular response to auxin stimulus
GO:0031087--P:deadenylation-independent decapping of nuclear-transcribed mRNA
GO:0009965--P:leaf morphogenesis
GO:0006402--P:mRNA catabolic process
GO:0006397--P:mRNA processing
GO:0009791--P:post-embryonic development
GO:0010072--P:primary shoot apical meristem specification
GO:0010071--P:root meristem specification

KEGG

ath:AT3G13300

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000944	Aegilops tauschii	46.48	0.00e+00	966.00
IUUC-Atr-002815	Amborella trichopoda	60.66	0.00e+00	652.00
IUUC-Aly-005827	Arabidopsis lyrata	95.37	0.00e+00	2408.00
IUUC-Bol-015150	Brassica oleracea	78.46	0.00e+00	1812.00
IUUC-Bra-017673	Brassica rapa	79.03	0.00e+00	1848.00
IUUC-Gma-044374	Glycine max	58.62	0.00e+00	1278.00
IUUC-Hvu-047830	Hordeum vulgare	49.03	0.00e+00	1059.00
IUUC-Lpe-051585	Leersia perrieri	49.09	0.00e+00	998.00
IUUC-Loc-051778	Lepisosteus oculatus	26.54	2.00e-27	117.00
IUUC-Mtr-057751	Medicago truncatula	59.69	0.00e+00	1232.00
IUUC-Mac-065564	Musa acuminata	66.52	0.00e+00	639.00
IUUC-Oba-075696	Oryza barthii	44.71	0.00e+00	672.00
IUUC-Ogl-077350	Oryza glaberrima	49.76	0.00e+00	1015.00
IUUC-Ogu-079010	Oryza glumaepatula	64.09	7.00e-171	594.00
IUUC-Olo-080844	Oryza longistaminata	46.79	0.00e+00	908.00
IUUC-Ome-081610	Oryza meridionalis	64.09	8.00e-171	594.00
IUUC-Opu-084175	Oryza punctata	49.10	0.00e+00	1002.00
IUUC-Oru-084677	Oryza rufipogon	49.55	0.00e+00	995.00
IUUC-Ppa-095912	Physcomitrella patens	52.45	9.00e-124	438.00
IUUC-Pop-100059	Populus trichocarpa	57.31	0.00e+00	1239.00
IUUC-Ppe-101310	Prunus persica	59.78	0.00e+00	688.00
IUUC-Sly-111353	Solanum lycopersicum	57.47	0.00e+00	1244.00
IUUC-Tca-121694	Theobroma cacao	56.33	0.00e+00	1350.00
IUUC-Tae-125495	Triticum aestivum	47.97	0.00e+00	1040.00
IUUC-Tur-126066	Triticum urartu	46.06	0.00e+00	928.00
IUUC-Vvi-130965	Vitis vinifera	60.79	0.00e+00	1342.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence