iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Protein 3D Structure
PDB	MMDB
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/PB1	1.00e-16	61.7	77	160

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/PB1

   S: 4    vkvsykgeirsfaldlekpgkfedLlkavrt.lt..........elknsevalkYeDedGDlvtlksDedldkavsllaskksllrlliqk 83
           vkvs++g+++++++dl+ + ++ +Llka++  ++          ++k+s + ++YeD+dGD++ l++D+++d++ s      s+ +l+i+k
   Q: 77   VKVSMDGAPYLRKIDLKMYKNYPELLKALENmFKftvgeysereGYKGSGFVPTYEDKDGDWM-LVGDVPWDMFSS------SCQKLRIMK 160
           9******************************73366999999*9*******************.************......999****98 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression.

Protein Sequence
(Fasta)

MEVTNGLNLK DTELRLGLPG AQEEQQLELS CVRSNNKRKN NDSTEESAPP PAKTQIVGWP 60
PVRSNRKNNN NKNVSYVKVS MDGAPYLRKI DLKMYKNYPE LLKALENMFK FTVGEYSERE 120

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Nucleotide Sequence
(Fasta)

CGTTAACCCT AATTTCAAAG CATCTTTCCT TATATAAATC TCTCTCTCTC CCTCACCATT 60
ACACAACACA CACAAGCATT TTCAAGGATA TCAAATCACA ATCCCAAGAA GAGCAATAAC 120

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Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0927--Auxin signaling pathway
KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro

IPR033389--AUX/IAA_dom
IPR003311--AUX_IAA
IPR000270--PB1_dom

PROSITE

PS51745--PB1

Pfam

PF02309--AUX_IAA

Gene Ontology

GO:0005634--C:nucleus
GO:0042802--F:identical protein binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0044212--F:transcription regulatory region DNA binding
GO:0009734--P:auxin-activated signaling pathway
GO:0009733--P:response to auxin
GO:0006351--P:transcription, DNA-templated

KEGG

ath:AT4G14560

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-005756	Arabidopsis lyrata	95.83	1.00e-69	254.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence