PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus GFI1B HECW1 16713569 hprd,biogrid,mint,intact exp P P G GP P P P P P P P P P P P P P P P HECW1 USP7 16713569 hprd,biogrid,mint,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G TNK2 HECW1 19144635 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G RNF43 HECW1 21108931 biogrid exp P GP P P P GP GP G P P G GP P GP GP G GP GP GP P GP P P GP G HECW1 FBXL15 21572392 biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G HECW1 MPHOSPH8 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G CACNA1A HECW1 21078624 biogrid,intact exp G G G G G GP G G G G G GP G G G GP GP G G G G G G G GP G G SCNN1A HECW1 11244092 biogrid exp GP GP P P P GP GP P GP GP G GP P P GP G P GP GP P GP P P GP G SCNN1B HECW1 11244092 biogrid exp GP GP G G P G GP G GP GP GP P G P P GP GP GP GP GP P P P G LDLRAD4 HECW1 26186194 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP P P P G SOD1 HECW1 14684739 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G MAPK6 HECW1 20936779 i2d exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G TP53 HECW1 18223681 biogrid exp G G G G G G G G G G G G G G G GP G G G G GP G G G GP GP G SSR4 HECW1 14684739 hprd,biogrid exp GP GP G G GP GP G G GP G G GP GP GP G GP GP G GP G GP GP GP G GP P P GP G HECW1 HECW2 24163370, 25402006 biogrid exp, pred GP GP G G GP GP G GP GP G GP G GP G G P GP P GP G GP GP GP GP GP P GP DVL1 HECW1 14684739, 25402006, 21836163 hprd,biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G SLC7A9 HECW1 25402006 pred G G G G G G G G G G GP G G G G GP G G G G G G G G GP G G UBE2H HECW1 16082366 pred GP GP G G GP GP G GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G GRM6 HECW1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G HECW1 BIRC6 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G NTRK3 HECW1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G HECW1 PIWIL2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G CDC34 HECW1 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G ATN1 HECW1 25402006 pred GP GP G G GP GP G GP GP G GP GP G G G GP GP GP GP G GP GP GP GP GP P P GP G HECW1 G6PC2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G HECW1 UFC1 16082366 pred GP GP G G G GP G GP GP G GP G GP G G GP GP G GP G GP GP GP GP GP P GP G NCR2 HECW1 25402006 pred G G G G G G G G G G GP G G G G G G G G G G G G G G G G DEFA5 HECW1 25402006 pred G G G G G G G G G G GP G G G G G G G G GP G G UBE2R2 HECW1 16082366 pred G G G G GP G G G G G G G G GP G G G G G G G G G G G P P G G UBE2U HECW1 16082366 pred P P P P P P P P P P P P P P P P P P P P GP UBE2D1 HECW1 16082366 pred GP G G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP GP G GP G P P GP G IFNA16 HECW1 25402006 pred P G G G P G G GP P G P GP G G G G P P P G HHLA1 HECW1 25402006 pred P G G G G P P P P P G G G G GP G GP P P G UBE2V2 HECW1 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G MPP3 HECW1 25402006 pred GP GP G G G GP G GP GP G GP GP G G G GP GP G GP G G G GP G GP P GP G HECW1 TTYH2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G HECW1 WWP1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G PSG6 HECW1 25402006 pred G GP G G G GP G G GP G GP GP GP G G G GP G G G GP G G G G P GP G UBE2D2 HECW1 16082366 pred GP G G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP GP G GP G P P GP G CSNK1E HECW1 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP P P GP G UBE2E1 HECW1 16082366 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP P GP G UBE2A HECW1 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G SMAD3 HECW1 25402006 pred GP GP G G G GP G G G G G G GP GP G G GP G GP G GP G G G G G G AXIN1 HECW1 25402006 pred GP GP G GP GP G P GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G CSNK1D HECW1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G ITPK1 HECW1 25402006 pred GP G G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP P GP G POU4F2 HECW1 25402006 pred G G G G G G G G G G G G HECW1 NPAP1 25402006 pred G G G G G GP G GP GP G G G G G G GP GP G G G G G G G GP GP G PSG9 HECW1 25402006 pred G GP G G G GP G G GP G GP GP GP G G G GP G G G GP G G G G P GP G CER1 HECW1 25402006 pred G G G G G G G G G G G G G GP G G G G G G G G G G G G G CPN1 HECW1 25402006 pred G GP G G G GP G GP G G GP GP G G G GP GP G G G GP GP GP GP GP P GP G GLYAT HECW1 25402006 pred G G G HECW1 UBE2E3 16082366 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP P GP G UBE2S HECW1 16082366 pred G G G G G G G G GP G G G GP G G G G G G G G G GP G UBE2B HECW1 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G HECW1 TTYH1 21836163 pred G GP G P G P G P GP P P P GP HECW1 AKTIP 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G IFNA4 HECW1 25402006 pred P G G G G GP G G GP GP G G P GP G G G G P P GP G HECW1 PGLYRP4 25402006 pred GP G G G GP GP G G GP G GP G GP GP G GP GP G GP G G GP GP G GP P P GP G UBE2I HECW1 16082366 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP P P GP G HECW1 TCTN2 25402006 pred GP G G G GP GP G GP GP G G G GP G G GP GP G GP G GP G G G GP P P GP G HECW1 GPRC5D 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G GSTA1 HECW1 25402006 pred G GP G G G G G G G G GP GP G G G GP G GP GP G G G G G GP P GP G DRD5 HECW1 25402006 pred G G G G G GP G G G G G G GP G G G GP G G G GP G G G G P GP G HECW1 SMURF2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G P2RY4 HECW1 25402006 pred G GP G G G GP G GP GP G G GP GP G G GP GP G GP G GP G GP GP GP P P GP G CNR2 HECW1 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP P P GP G IFNA17 HECW1 25402006 pred GP G G G G GP G G GP G GP G G G G GP GP G G G G G G G GP P GP G CYP2A6 HECW1 25402006 pred G G G G G G G G G G G GP G G G G G G G G G G G G G P G G RFPL3 HECW1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G SMAD7 HECW1 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P P G CSH2 HECW1 25402006 pred HECW1 SMURF1 25402006 pred G GP G G GP GP G G GP G GP G GP G G G GP GP G G GP G G G G P GP G EGFR HECW1 25402006 pred GP GP G GP G G GP G GP GP G G G GP GP G G G GP GP G GP GP P GP G HECW1 KCNMB4 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G HECW1 ZNF835 25402006 pred P P P G P P P P P P P P P P P P HECW1 PIK3R5 25402006 pred GP GP G G GP G G G GP G GP G GP G GP G G GP G GP G GP GP P P GP G HECW1 UBE2T 16082366 pred G G G GP G GP P P P GP GP P GP P G GP P GP G XDH HECW1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G FASLG HECW1 25402006 pred P GP G G GP GP G G GP G GP G P G P GP GP GP G GP P GP GP P P P GP G HECW1 UBE2Z 16082366 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP P P GP G KIF5A HECW1 25402006 pred GP GP G G GP GP G GP GP G GP GP P GP G GP GP G GP G GP GP GP GP GP P P GP G ITGA10 HECW1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2N HECW1 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP P P GP G HECW1 CPA4 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G GPR12 HECW1 25402006 pred G G G G G G G G G G GP GP G G G GP G G G G G G G G P G G KRT38 HECW1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G P GP GP GP G GP GP GP GP P P P GP G UBE2G1 HECW1 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G HECW1 TTYH3 21836163 pred G GP G G G GP G GP GP G GP GP G G G GP GP GP G G G GP GP G GP GP G NEUROD2 HECW1 25402006 pred G G G G G G G G G G G G G G G G G G G GP G G G G G G UBE2C HECW1 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G DAO HECW1 25402006 pred G G G G G GP G G G G GP GP G G G G GP G G G G G G G G G G HECW1 HAO2 25402006 pred G G G G G GP G GP G G GP GP GP G P GP G GP G GP GP GP GP GP P GP G KRT2 HECW1 25402006 pred GP G G G G G G G G G G G G G G G G G G G G G G G G G G CD80 HECW1 25402006 pred G G G G GP GP G G G G G G G GP G G GP G G G GP G G G G P G G HECW1 CHST4 25402006 pred GP G G G G G G GP G G G GP G G G G G G GP G G G G G G G G SEC14L5 HECW1 25402006 pred GP GP G G G GP G G GP G GP G GP G G GP GP G GP G G G GP G GP P GP G HECW1 TAS2R16 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G OR10H3 HECW1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G HECW1 MYO16 25402006 pred G GP P P P P GP P P P P P TSHB HECW1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G HECW1 OR2S2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G HECW1 TAF4B 25402006 pred G GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G G GP GP GP P GP G HECW1 HS3ST2 25402006 pred G GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP G G G GP P GP G SLC6A12 HECW1 25402006 pred G GP G G G GP G GP P G GP GP GP G GP GP G G G GP G GP G GP P GP G HECW1 UBE2F 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP P P GP G UBE2L3 HECW1 16082366 pred GP G G G G GP G GP GP G GP G G G G GP GP G GP G G G GP GP GP P GP G UBE2M HECW1 16082366 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP G GP GP GP P P GP G HECW1 TRIM10 25402006 pred G G G G G G G G G G G G G G GP G GP G G G G G GP GP P GP G IFNA14 HECW1 25402006 pred P G G G G GP G G P G GP G GP GP G G G G G P P GP G HECW1 LGALS14 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G HECW1 SMAD5 25402006 pred GP GP G G G GP G G GP G GP GP GP G G G GP GP G G GP GP G G G GP G HECW1 A1CF 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G GP G G G G G GP P G G HECW1 16082366 pred C1orf105 HECW1 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP GP GP GP G P GP G HECW1 TSG101 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G GPR182 HECW1 25402006 pred G G G G G G G GP P GP G G P G G G G G G G P GP G FGF5 HECW1 25402006 pred P P P P G G P P GP P P P GP GP GP P P P P P P P GP G ART1 HECW1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G HECW1 DVL3 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G POLR2A HECW1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G UBE2L6 HECW1 16082366 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP P P GP G ACRV1 HECW1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G GP G HECW1 ADAMTS9 25402006 pred GP GP G G GP GP G GP GP GP GP GP G G GP GP GP GP G GP G GP GP GP P GP G CPA2 HECW1 25402006 pred G G G G G G G G G G G G G G G G G G GP G G G G G G G G SMAD2 HECW1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G HECW1 SLC30A3 25402006 pred G GP P P P P GP P P P GP HECW1 UBE2D4 16082366 pred GP G G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP GP G GP G P P GP G HECW1 CTAGE1 25402006 pred P P G G GP GP G G GP G P GP P GP P GP GP GP G P GP G P P P GP G GTDC1 HECW1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G P GP G GP G GP GP GP GP GP P P GP G EPS8 HECW1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G HECW1 ZNF507 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P P GP G BMP15 HECW1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G IFNA7 HECW1 25402006 pred GP G G G G GP G G GP G GP G G G GP GP G G G G G G GP P GP G HECW1 CCDC9 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP P P GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q68DV7 Q76N89 two hybrid 21108931 direct interaction X 2 Q68DV7 Q76N89 affinity chromatography technology 21108931 physical association X 2 B2R812 Q76N89 far western blotting 11244092 direct interaction X 2 P00441 Q76N89 affinity chromatography technology 14684739 physical association X 2 Q76N89 pull down 19144635 direct interaction X 2 Q76N89 two hybrid 21078624 direct interaction X 2 P0CG48 Q76N89 affinity chromatography technology 21906983 physical association X 2 Q93009 Q76N89 two hybrid 16713569 direct interaction X 2 Q9P2P5 Q76N89 affinity chromatography technology 24163370 physical association X 2 Q76N89 P04637-7 affinity chromatography technology 18223681 physical association X 2 Q76N89 P04637-7 pull down 18223681 direct interaction X 2 Q76N89 A0A024R8F3 two hybrid 16713569 direct interaction X 2 Q76N89 O14640-2 two hybrid 14684739 direct interaction X 2 Q76N89 Q9H469 affinity chromatography technology 21572392 physical association X 2 Q76N89 affinity chromatography technology 14684739 physical association X 2 Q76N89 O14640-2 affinity chromatography technology 14684739 physical association X 2 Q76N89 P37088-2 far western blotting 11244092 direct interaction X 2 Q5VTD9-2 Q76N89 two hybrid 16713569 - X 2 Q5VTD9-2 Q76N89 two hybrid 16713569 - X 2 P51571 Q76N89 in vitro 14684739 - X 2 P51571 Q76N89 two hybrid 14684739 - X 2 P51571 Q76N89 in vitro 14684739 - X 2 P51571 Q76N89 two hybrid 14684739 - X 2 Q93009 Q76N89 two hybrid 16713569 - X 2 Q93009 Q76N89 two hybrid 16713569 - X 2 Q76N89 O14640-2 in vivo 14684739 - X 2 Q76N89 O14640-2 two hybrid 14684739 - X 2 Q76N89 O14640-2 in vivo 14684739 - X 2 Q76N89 O14640-2 two hybrid 14684739 - X 2 Q76N89 O00555 two hybrid 21078624 physical association X 2 Q93009 Q76N89 two hybrid 16713569 physical association X 2 Q76N89 Q9H469 anti tag coimmunoprecipitation 21572392 physical association X 2 Q5VTD9 Q76N89 two hybrid 16713569 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B CACNA1A HECW1 MI:0018(two hybrid)|MI:0018(two hybrid) 21078624 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_147587|UniProt_110072 bait|bait prey|prey p53 HECW1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 18223681 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_197605|BIOGRID_197606 prey|prey bait|bait TNK2 HECW1 MI:0096(pull down) 19144635 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_145411 prey bait HECW1 USP7 MI:0397(two hybrid array)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0096(pull down) 16713569 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|-|MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid)|MI:0468(hprd)|MI:0471(mint)|MI:0471(mint) UniProt_86505|BIOGRID_215926|HPRD_27116|MINT_82886|MINT_50598 prey|prey|-|prey|prey bait|bait|-|bait|bait UBC HECW1 MI:0018(two hybrid)|MI:0004(affinity chromatography technology) 14684739,21906983 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_217198|BIOGRID_178282 prey|bait bait|prey RNF43 HECW1 MI:0018(two hybrid)|MI:0018(two hybrid) 21108931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_200162|BIOGRID_200163 bait|bait prey|prey HECW1 FBXL15 MI:0018(two hybrid)|MI:0004(affinity chromatography technology) 21572392 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_115326|BIOGRID_258624 bait|bait prey|prey HECW1 HECW2 MI:0004(affinity chromatography technology) 24163370 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_293805 prey bait GFI1B HECW1 MI:0397(two hybrid array)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0096(pull down)|MI:0018(two hybrid) 16713569 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|- (intact)|(biogrid)|MI:0471(mint)|MI:0471(mint)|MI:0468(hprd) UniProt_86391|BIOGRID_215827|MINT_82885|MINT_50597|HPRD_32398 bait|bait|bait|bait|- prey|prey|prey|prey|- SCNN1A HECW1 MI:0047(far western blotting) 11244092 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_109060 bait prey SOD1 HECW1 MI:0018(two hybrid) 14684739 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_87222 bait prey DVL1 HECW1 MI:0492(in vitro)|MI:0018(two hybrid)|MI:0018(two hybrid) 14684739 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0407(direct interaction) MI:0468(hprd)|(biogrid)|(biogrid) HPRD_8980|BIOGRID_87224|BIOGRID_77784 -|prey|prey -|bait|bait SSR4 HECW1 MI:0018(two hybrid)|MI:0492(in vitro) 14684739 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_87221|HPRD_5221 bait|- prey|- SCNN1B HECW1 MI:0047(far western blotting) 11244092 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_109064 bait prey

PPI - HINT Gene A Gene B PMID Method Quality LDLRAD4 HECW1 26186194 0004 HT HECW1 MPHOSPH8 26496610,26496610 0007,0004 HT LDLRAD4 HECW1 26186194 0004 HT HECW1 MPHOSPH8 26496610,26496610 0007,0004 HT CACNA1A HECW1 21078624 0018 HT DVL1 HECW1 14684739,14684739,18223681 0004,0018,0415 LC UBC HECW1 25723849 0415 LC SCNN1A HECW1 11244092 0047 LC SCNN1B HECW1 11244092 0047 LC SSR4 HECW1 14684739,14684739 0018,0004 LC GFI1B HECW1 16713569 0018 HT RNF43 HECW1 21108931,21108931 0004,0018 LC HECW1 HECW1 26949039 0415 LC HECW1 USP7 16713569 0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q76N89 O15165 HECW1 LDLRAD4 0.126 26186194 Q9H469 Q76N89 FBXL15 HECW1 0.376 21572392 Q76N89 P0CG48 HECW1 UBC 0.309 25723849 Q76N89 P51668 HECW1 UBE2D1 0.309 25723849 Q76N89 P61077 HECW1 UBE2D3 0.309 25723849 Q76N89 P62837 HECW1 UBE2D2 0.309 25723849 Q76N89 P68036 HECW1 UBE2L3 0.309 25723849 Q76N89 Q07912 HECW1 TNK2 0.309 19144635 Q76N89 Q5VTD9 HECW1 GFI1B 0.454 16713569 Q76N89 Q76N89 HECW1 HECW1 0.332 26949039 Q8N2K1 Q76N89 UBE2J2 HECW1 0.309 26949039 Q76N89 P14335 HECW1 P14335 0.126 22014111 Q76N89 P00441 HECW1 SOD1 0.21 14684739 Q76N89 Q68DV7 HECW1 RNF43 0.454 21108931 Q76N89 O14640 HECW1 DVL1 0.454 14684739 Q76N89 P04637 HECW1 TP53 0.454 18223681 Q93009 Q76N89 USP7 HECW1 0.332 16713569 Q76N89 P37088 HECW1 SCNN1A 0.309 11244092 Q99549 Q76N89 MPHOSPH8 HECW1 0.126 26496610 Q9P2P5 Q76N89 HECW2 HECW1 0.126 24163370 Q76N89 P51168 HECW1 SCNN1B 0.309 11244092 Q76N89 P51571 HECW1 SSR4 0.21 14684739 Q76N89 O00555 HECW1 CACNA1A 0.332 21078624

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 CACNA1A HECW1 MI:0045 experimental interaction detection MI:0461 interaction database DVL1 HECW1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database LDLRAD4 HECW1 MI:0045 experimental interaction detection MI:0461 interaction database SOD1 HECW1 MI:0045 experimental interaction detection MI:0461 interaction database TP53 HECW1 MI:0045 experimental interaction detection MI:0461 interaction database UBB HECW1 MI:0362 inference MI:1106 pathways database UBC HECW1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SCNN1A HECW1 MI:0045 experimental interaction detection MI:0461 interaction database SCNN1B HECW1 MI:0045 experimental interaction detection MI:0461 interaction database SSR4 HECW1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D1 HECW1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D3 HECW1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D2 HECW1 MI:0045 experimental interaction detection MI:0461 interaction database RPS27A HECW1 MI:0362 inference MI:1106 pathways database UBA52 HECW1 MI:0362 inference MI:1106 pathways database UBE2L3 HECW1 MI:0045 experimental interaction detection MI:0461 interaction database TNK2 HECW1 MI:0045 experimental interaction detection MI:0461 interaction database GFI1B HECW1 MI:0045 experimental interaction detection MI:0461 interaction database RNF43 HECW1 MI:0045 experimental interaction detection MI:0461 interaction database HECW1 UBE2J2 MI:0045 experimental interaction detection MI:0461 interaction database HECW1 USP7 MI:0045 experimental interaction detection MI:0461 interaction database HECW1 MPHOSPH8 MI:0045 experimental interaction detection MI:0461 interaction database HECW1 FBXL15 MI:0045 experimental interaction detection MI:0461 interaction database HECW1 HECW2 MI:0045 experimental interaction detection MI:0461 interaction database