PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus HSPB1 ASB4 24337577 biogrid exp P G G G G G G P G G P G P G G G P G RNF7 ASB4 24337577 biogrid exp P G G G GP G G P GP GP G P G G G P G HIF1AN ASB4 26186194,17636018 hprd,biogrid exp P G G G GP G G P GP GP P G P G G G P G DNAJB4 ASB4 24337577 biogrid exp P G G G GP G G P GP GP P G P G G G P G TUBB2A ASB4 24337577 biogrid exp P G G G GP G G P GP GP G P G G G G RPS27L ASB4 24337577 biogrid exp G G G G G G G G G G G G G HSPB8 ASB4 24337577 biogrid exp P G GP G G P GP GP G P G G G P G TUBB3 ASB4 24337577 biogrid exp P G G G GP G G P GP GP P G P G G G P G UBE2D1 ASB4 24586788 biogrid exp P G G G GP G G P GP GP P G P G G G P G TCEB2 ASB4 17636018 biogrid exp G G G G G G G G G G G G G TFRC ASB4 24337577 biogrid exp P G G G GP G G P GP GP P G P G G G P G DDB1 ASB4 24337577 biogrid exp P G G G GP G G P GP GP P G P G G G P G HSPD1 ASB4 24337577 biogrid exp P G G G GP G G P GP GP P G P G G G P G ASB4 ASB4 17636018 hprd exp P G G G GP G G P GP GP P G P G G G P G ASB7 ASB4 24337577 biogrid exp P G G G GP G G P GP GP P G P G G G P G TUBB4A ASB4 24337577 biogrid exp P G G G GP G G P GP GP P G P G G G P G HSP90AB1 ASB4 22939624 intact exp P G G G GP G G P GP GP P G P G G G P G TUBB8 ASB4 24337577 biogrid exp P P P P P P P ID2 ASB4 24586788 biogrid exp P G G G GP G G P GP GP P G P G G G P G STUB1 ASB4 24337577 biogrid exp P G G G GP G G P GP GP P G P G G G P G CUL2 ASB4 17636018 biogrid exp P G G G GP G G P GP GP P G P G G G P G FARSA ASB4 24337577 biogrid exp P G G G GP G G P GP GP P G P G G G P G DNAJB5 ASB4 26186194,24337577 biogrid exp P G G G GP G G P GP GP P G P G G G P G CUL4A ASB4 24337577 biogrid exp G G G G G G G G G G G G G CUL5 ASB4 24337577,17636018 biogrid exp P G G G GP G G P GP GP P G P G G G P G HSP90AA1 ASB4 22939624 biogrid exp P G G G GP G G G GP G P G G G P G RIT1 ASB4 17636018 biogrid exp P G G G GP G G P G GP P G P G G G P G GPS1 ASB4 17276034, 21836163 biogrid exp, pred G G G G G G G G G G G G G VHL ASB4 25402006 pred G G G G G G P G G G G G G P G HIF1A ASB4 25402006 pred P G G G GP G G P GP GP G P G G G P G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9UNE7 Q9Y574 affinity chromatography technology 24337577 physical association X 2 Q3ZCM7 Q9Y574 affinity chromatography technology 24337577 physical association X 2 Q9UJY1 Q9Y574 affinity chromatography technology 24337577 physical association X 2 Q9UDY4 Q9Y574 affinity chromatography technology 24337577 physical association X 2 Q13617 Q9Y574 affinity chromatography technology 17636018 physical association X 2 Q9Y574 G3UXW9 affinity chromatography technology 17276034 physical association X 2 Q9Y574 Q13098-5 affinity chromatography technology 17276034 physical association X 2 Q9Y574 Q13098-5 affinity chromatography technology 17276034 physical association X 2 Q9Y574 B2RBV7 affinity chromatography technology 24337577 physical association X 2 Q9Y574 A8K6Q8 affinity chromatography technology 24337577 physical association X 2 Q9Y574 Q53G92 affinity chromatography technology 24337577 physical association X 2 Q9Y574 B2RBV7 affinity chromatography technology 24337577 physical association X 2 Q9Y574 Q02363 affinity chromatography technology 24586788 physical association X 2 Q9Y574 Q02363 affinity chromatography technology 24586788 physical association X 2 Q9Y574 Q02363 enzymatic study 24586788 direct interaction X 2 Q9Y574 Q15370-2 affinity chromatography technology 17636018 physical association X 2 Q9Y574 Q92963 affinity chromatography technology 17636018 physical association X 2 Q9Y574 Q9NWT6 affinity chromatography technology 17636018 physical association X 2 Q9Y574 Q9NWT6 two hybrid 17636018 direct interaction X 2 Q71UM5 Q9Y574 affinity chromatography technology 24337577 physical association X 2 Q6IBR2 Q9Y574 affinity chromatography technology 24337577 physical association X 2 A0A087WW00 Q9Y574 pull down 24586788 direct interaction X 2 Q13885 Q9Y574 affinity chromatography technology 24337577 physical association X 2 Q9Y574 P07900-2 affinity chromatography technology 22939624 physical association X 2 Q9Y574 Q93034 affinity chromatography technology 24337577 physical association X 2 Q9Y574 O75953 affinity chromatography technology 24337577 physical association X 2 Q9Y574 P04350 affinity chromatography technology 24337577 physical association X 2 Q9Y574 P04792 affinity chromatography technology 24337577 physical association X 2 Q9Y574 A0A024R3X4 affinity chromatography technology 24337577 physical association X 2 Q9Y574 Q9UBF6-2 affinity chromatography technology 24337577 physical association X 2 Q9Y574 A0A024RC94 affinity chromatography technology 24337577 physical association X 2 Q9Y574 A0A024RC94 affinity chromatography technology 24337577 physical association X 2 Q9Y574 Q16531 affinity chromatography technology 24337577 physical association X 2 Q9Y574 Q93034 affinity chromatography technology 24337577 physical association X 2 Q9Y574 Q93034 affinity chromatography technology 17636018 physical association X 2 Q9Y574 A0A024RD80 luminescence based mammalian interactome mapping 22939624 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B TUBB8 ASB4 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309647 prey bait RPS27L ASB4 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309657 prey bait STUB1 ASB4 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309652 prey bait DDB1 ASB4 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_310011 prey bait ASB4 ASB4 MI:0493(in vivo) 17636018 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_33384 - - TCEB2 ASB4 MI:0004(affinity chromatography technology)|MI:0493(in vivo) 17636018 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_118095|HPRD_40087 prey|- bait|- HSP90AA1 ASB4 MI:0004(affinity chromatography technology) 22939624 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_255406 bait prey TUBB3 ASB4 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309649 prey bait RIT1 ASB4 MI:0004(affinity chromatography technology)|MI:0493(in vivo) 17636018 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_118096|HPRD_40087 prey|- bait|- GPS1 ASB4 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17276034 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_201388|BIOGRID_201389 prey|bait bait|prey RNF7 ASB4 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309658 prey bait TUBB4A ASB4 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309654 prey bait HSPB8 ASB4 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309646 prey bait CUL5 ASB4 MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17636018,24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid) HPRD_40087|BIOGRID_309648|BIOGRID_118094|BIOGRID_310013 -|prey|prey|prey -|bait|bait|bait DNAJB5 ASB4 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309650 prey bait DNAJB4 ASB4 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309653 prey bait FARSA ASB4 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309651 prey bait HSPB1 ASB4 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309655 prey bait TUBB2A ASB4 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309659 prey bait CUL4A ASB4 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_309644|BIOGRID_310012 prey|prey bait|bait HSPD1 ASB4 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309656 prey bait HSP90AB1 ASB4 MI:0729(luminescence based mammalian interactome mapping) 22939624 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_124961 prey bait HIF1AN ASB4 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0493(in vivo) 17636018 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|- (biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_118097|BIOGRID_118098|HPRD_33385 prey|prey|- bait|bait|- ASB7 ASB4 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_309720|BIOGRID_310010 bait|bait prey|prey CUL2 ASB4 MI:0004(affinity chromatography technology)|MI:0493(in vivo) 17636018 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_118093|HPRD_40087 prey|- bait|- TFRC ASB4 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309645 prey bait

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9Y574 Q9H672 ASB4 ASB7 0.126 24337577 Q9Y574 P07900 ASB4 HSP90AA1 0.126 22939624 Q9Y574 P10809 ASB4 HSPD1 0.126 24337577 Q9Y574 Q13509 ASB4 TUBB3 0.126 24337577 Q9Y574 Q9Y285 ASB4 FARSA 0.126 24337577 Q9Y574 P04792 ASB4 HSPB1 0.126 24337577 Q9Y574 P08238 ASB4 HSP90AB1 0.126 22939624 Q9Y574 P02786 ASB4 TFRC 0.126 24337577 Q9Y574 P04350 ASB4 TUBB4A 0.126 24337577 Q9Y574 P51668 ASB4 UBE2D1 0.309 24586788 Q9Y574 Q9UNE7 ASB4 STUB1 0.126 24337577 Q9Y574 Q13617 ASB4 CUL2 0.21 17636018 Q9Y574 Q92963 ASB4 RIT1 0.21 17636018 Q9Y574 Q13885 ASB4 TUBB2A 0.126 24337577 Q9Y574 Q13619 ASB4 CUL4A 0.126 24337577 Q9Y574 Q71UM5 ASB4 RPS27L 0.126 24337577 Q9Y574 Q16531 ASB4 DDB1 0.126 24337577 Q9Y574 Q15370 ASB4 TCEB2 0.21 17636018 Q9Y574 Q3ZCM7 ASB4 TUBB8 0.126 24337577 Q9Y574 Q9UJY1 ASB4 HSPB8 0.126 24337577 Q9Y574 Q9UDY4 ASB4 DNAJB4 0.126 24337577 Q9Y574 Q9UBF6 ASB4 RNF7 0.126 24337577 Q9Y574 O75953 ASB4 DNAJB5 0.236 24337577,26186194 Q9Y574 Q93034 ASB4 CUL5 0.309 17636018,24337577 Q9Y574 Q9NWT6 ASB4 HIF1AN 0.523 17636018,26186194 Q9Y574 Q13098 ASB4 GPS1 0.376 17276034 Q9Y574 Q02363 ASB4 ID2 0.569 24586788