PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus MTAP MYLIP 12826659 hprd,mint exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G MIPOL1 MYLIP 25416956 biogrid,intact exp G G G MYLIP DAPP1 25814554 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RASSF5 MYLIP 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP TSC22D4 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CRK MYLIP 25814554 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G VLDLR MYLIP 21734303,22109552 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G KDM1A MYLIP 23455924 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G LRP8 MYLIP 22109552 biogrid exp G G G G G G G G G G G G G G G SRPK2 MYLIP 26167880 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G LNX2 MYLIP 21516116 biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2D2 MYLIP 21685362, 23023127 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G LDLR MYLIP 21685362,21734303,22109552, 23023127 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2N MYLIP 21734303, 23023127 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP MYLIP 21685362,12826659, 23023127 biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP CNPY2 12826659, 21836163 hprd,biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYL12B MYLIP 10593918, 25402006 hprd,biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP UBE2D4 21685362, 23023127 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2D3 MYLIP 21685362, 23023127 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2D1 MYLIP 21734303,21685362, 23023127 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP SGSM3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP CYLD 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G UCHL3 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP FAF1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TGFB1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G USP14 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP UBQLN2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2H MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM32 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SUMO2 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM13 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP EPB41L3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G PXK MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM21 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PLD1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G PJA1 MYLIP 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP NAPG 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP DEF6 23023127 pred G G G G G G G G G G G G G G G G G G G G MYLIP CPEB1 23023127 pred G G G G G G G G G MYLIP SH3GLB2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP AGAP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP USP44 23023127 pred G G G IRS1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G VAV2 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2B MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SLC9A3R1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLK MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G AKT1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP PLEKHA1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP STUB1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DVL2 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G LDLRAP1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CAV3 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G ARHGAP5 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RING1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MARCH8 MYLIP 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ADAP1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF13 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CDC34 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP GAB2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MAP3K11 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SQSTM1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CNOT4 MYLIP 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP AGAP4 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G FGD6 MYLIP 23023127 pred G G UBE2L3 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF103 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G STX12 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP RNF2 23023127 pred G SYK MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G CIDEA MYLIP 23023127 pred G G G G G G G G MYLIP ITCH 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NFX1 MYLIP 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP UBE2T 23023127 pred G G G G G G G G G G G G G DNM2 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP UHRF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SPOCK1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP AKTIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP DVL3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ADIPOQ MYLIP 23023127 pred G G G G G G G G G G G G G G G G G RBBP6 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G AXIN1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G DNAJB2 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP PACSIN3 23023127 pred G G G G G G G G G G G G G G G G G G G FRMD5 MYLIP 23023127 pred G G G G G G G G G ARHGEF7 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP UBE2E3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE3C MYLIP 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G FGD1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G BMI1 MYLIP 23023127 pred ABI1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2M MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GIPC1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP RNF7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G HTR2A MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP RNF25 21836163 pred G G PRKCD MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G FGD3 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP EHD1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP ARAP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G APOA2 MYLIP 23023127 pred G G MYLIP USP3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SUMO3 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G USP5 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GABARAPL2 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G HUWE1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP FARP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP TRIM11 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP TRIM5 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G MYLIP ALS2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GPIHBP1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G MYLIP RNF11 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DYSF MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MAP3K1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G FARP2 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RAD23B MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP UBQLN1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP GIT1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SMAD7 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G NPC2 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NEDD4 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G GCLC MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP CD2AP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G MSN MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP SMURF1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CYTH1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GIT2 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP SENP2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP USP21 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SCAP MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UFM1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF144B MYLIP 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G AKT2 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2G2 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GRB2 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP AMFR 23023127, 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP FRMD4A 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MDM2 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP FANCL 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP COL4A3BP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP TRIM9 23023127 pred G G G G G G G G G G G UBE2E1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP ADAP2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G SUMO1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP TRIM63 23023127 pred G G G G MYLIP UHRF1 21836163 pred G G G G G G G G G G G G G G G CBLB MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MAP3K9 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G DMD MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G AGAP8 MYLIP 23023127 pred RDX MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP CHFR 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2R2 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2G1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP USP7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP SOX17 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G PCSK9 MYLIP 23023127 pred G G G G G G G G G G G MYLIP UBE2E2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RAD23A MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SMAD4 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP ASAP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP EPB41L4B 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G MGRN1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP RNF41 23023127 pred G G G G G G G G G G G G G G G G G G G G G MYLIP RASSF1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G MIB1 MYLIP 23023127, 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G BRAP MYLIP 21836163 pred G G G G G G G G G G G APBB1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP UBA2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2K MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SLC35E3 MYLIP 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP NEDD4L 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G NF2 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G EPB41 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G VAV1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G MYLIP AGAP3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G MYLIP SENP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP ANLN 23023127 pred G G G G G G G G G G G MYL12A MYLIP 21836163 pred UBE2I MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRAF7 MYLIP 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PRKCG MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G UBE2V2 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G IGF1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G PRKCQ MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP EPB41L5 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G HERPUD1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G BIN1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G FRMD3 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP SH3KBP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G AMPH MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP DNM3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G RNF220 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NCF1B MYLIP 23023127 pred ARRB1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP ATG4B 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP TRAF6 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DVL1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP CCNB1IP1 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP FBXO7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP PLEKHH1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP DOCK10 23023127 pred G G G G G G G G G G G G G G G G MYLIP WWP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G APOC2 MYLIP 23023127 pred G MYLIP TBC1D2 23023127 pred G G G G G G PARK2 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G PEX2 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP IRS2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ASGR2 MYLIP 23023127 pred G G G G MYLIP RCHY1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOX4 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PLCG2 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MDM4 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DFFB MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G PTPN3 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2V1 MYLIP 23023127 pred TPO MYLIP 21836163 pred G MSR1 MYLIP 23023127 pred G G G G G G G G G AGAP11 MYLIP 23023127 pred G G G G G G G G G G G G SKAP1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G USP2 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G LNX1 MYLIP 23023127, 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G AGAP7P MYLIP 23023127 pred CD36 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G WDSUB1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G FRMD7 MYLIP 23023127 pred CTSH MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP VAV3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBOX5 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G ACAP1 MYLIP 23023127 pred G G G G G G G TIAM1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SBF1 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP HIPK3 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP NUB1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP RNF5 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PLEK MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants A0A087WW00 Q8WY64 pull down 21685362 direct interaction X 2 A0A087WW00 Q8WY64 pull down 21734303 direct interaction X 2 A0A087WW00 Q8WY64 x-ray crystallography 21685362 association X 2 P98155-2 Q8WY64 unspecified method 22109552 direct interaction X 2 P98155-2 Q8WY64 affinity chromatography technology 21734303 physical association X 2 Q8WY64 A0A024RA90 pull down 21685362 direct interaction X 2 Q8WY64 O60341 two hybrid 23455924 direct interaction X 2 P61088 Q8WY64 pull down 21734303 direct interaction X 2 O14950 Q8WY64 two hybrid 10593918 direct interaction X 2 O14950 Q8WY64 affinity chromatography technology 10593918 physical association X 2 Q9Y3Q8 Q8WY64 two hybrid 25416956 direct interaction X 2 P01130-5 Q8WY64 unspecified method 22109552 direct interaction X 2 P01130-5 Q8WY64 enzymatic study 21734303 direct interaction X 2 P01130-5 Q8WY64 affinity chromatography technology 21734303 physical association X 2 P01130-5 Q8WY64 enzymatic study 21685362 direct interaction X 2 Q8WY64 unspecified method 22109552 direct interaction X 2 Q8WY64 P62837 pull down 21685362 direct interaction X 2 Q8WY64 P61077-3 pull down 21685362 direct interaction X 2 Q8WY64 Q8WWW0-2 two hybrid 25416956 direct interaction X 2 Q8WY64 Q9Y2B0 two hybrid 12826659 direct interaction X 2 Q8WY64 Q8WY64 pull down 12826659 direct interaction X 2 Q8WY64 Q9Y2B0 pull down 12826659 direct interaction X 2 Q8WY64 Q9Y2B0 affinity chromatography technology 12826659 physical association X 2 Q8WY64 Q8WY64 enzymatic study 21685362 direct interaction X 2 Q8WY64 Q8WY64 affinity chromatography technology 21685362 physical association X 2 Q8TD10 Q8WY64 two hybrid 25416956 direct interaction X 2 P0CG48 Q8WY64 affinity chromatography technology 22109552 physical association X 2 P0CG48 Q8WY64 pull down 21685362 direct interaction X 2 P0CG48 Q8WY64 affinity chromatography technology 22378787 physical association X 2 O14950 Q8WY64 two hybrid 10593918 - X 2 O14950 Q8WY64 in vivo 10593918 - X 2 O14950 Q8WY64 in vivo 10593918 - X 2 O14950 Q8WY64 two hybrid 10593918 - X 2 Q8WY64 Q9Y2B0 in vivo 12826659 - X 2 Q8WY64 Q9Y2B0 two hybrid 12826659 - X 2 Q8WY64 Q9Y2B0 in vitro 12826659 - X 2 Q8WY64 Q9Y2B0 in vitro 12826659 - X 2 Q8WY64 Q9Y2B0 in vivo 12826659 - X 2 Q8WY64 Q9Y2B0 two hybrid 12826659 - X 2 Q13126 Q8WY64 in vitro 12826659 - X 2 Q13126 Q8WY64 two hybrid 12826659 - X 2 Q13126 Q8WY64 in vitro 12826659 - X 2 Q13126 Q8WY64 two hybrid 12826659 - X 2 Q8N448 Q8WY64 two hybrid 21516116 physical association X 2 Q8WY64 O60341 two hybrid 23455924 physical association X 2 Q9Y3Q8 Q8WY64 two hybrid prey pooling approach 25416956 physical association X 2 Q9Y3Q8 Q8WY64 two hybrid array 25416956 physical association X 2 Q9Y3Q8 Q8WY64 validated two hybrid 25416956 physical association X 2 Q8WWW0 Q8WY64 two hybrid prey pooling approach 25416956 physical association X 2 Q8WWW0 Q8WY64 two hybrid array 25416956 physical association X 2 Q8WWW0 Q8WY64 validated two hybrid 25416956 physical association X 2 Q13126 Q8WY64 coimmunoprecipitation 12826659 physical association X 2 Q13126 Q8WY64 two hybrid 12826659 physical association X 2 Q8TD10 Q8WY64 two hybrid prey pooling approach 25416956 physical association X 2 Q8TD10 Q8WY64 two hybrid array 25416956 physical association X 2 Q8TD10 Q8WY64 validated two hybrid 25416956 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B KDM1A MYLIP MI:0018(two hybrid)|MI:0004(affinity chromatography technology) 23455924 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_129561|BIOGRID_297583 bait|prey prey|bait UBE2N MYLIP MI:0415(enzymatic study) 21734303 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_222968 prey bait LRP8 MYLIP MI:0004(affinity chromatography technology) 22109552 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_199562 prey bait MYLIP UBE2D4 MI:0415(enzymatic study) 21685362 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_222896 bait prey MYLIP CNPY2 MI:0493(in vivo)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 12826659 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid) HPRD_15911|BIOGRID_88947|BIOGRID_88949|BIOGRID_88950 -|bait|bait|bait -|prey|prey|prey UBC MYLIP MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology) 21685362,22109552,22378787 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_199559|BIOGRID_154628|BIOGRID_185357 prey|prey|prey bait|bait|bait VLDLR MYLIP MI:0004(affinity chromatography technology)|MI:0415(enzymatic study) 21734303,22109552 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_199561|BIOGRID_142261 prey|bait bait|prey MTAP MYLIP MI:0019(coimmunoprecipitation)|MI:0019(coimmunoprecipitation)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0493(in vivo)|MI:0018(two hybrid) 12826659 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association) (intact)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0468(hprd)|MI:0471(mint) UniProt_73057|UniProt_73056|MINT_85676|MINT_85675|MINT_56615|HPRD_37476|MINT_56614 bait|bait|bait|bait|bait|-|bait prey|prey|prey|prey|prey|-|prey UBE2D3 MYLIP MI:0415(enzymatic study) 21685362 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_222895 prey bait LDLR MYLIP MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0415(enzymatic study) 21685362,21734303,22109552 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_199560|BIOGRID_142259|BIOGRID_142260|BIOGRID_154630 prey|prey|bait|prey bait|bait|prey|bait UBE2D1 MYLIP MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0415(enzymatic study) 21685362,21734303 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0914(association) (biogrid)|(biogrid)|(biogrid) BIOGRID_222967|BIOGRID_222893|BIOGRID_154631 prey|prey|prey bait|bait|bait UBE2D2 MYLIP MI:0415(enzymatic study) 21685362 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_222894 prey bait MYL12B MYLIP MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0493(in vivo) 10593918 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|- (biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_213977|BIOGRID_213976|HPRD_15464 prey|prey|- bait|bait|- LNX2 MYLIP MI:0018(two hybrid) 21516116 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_114229 prey bait

PPI - HINT Gene A Gene B PMID Method Quality LDLR MYLIP 26666640,23382078,21734303,21734303 0004,0428,0004,0415 LC UBC MYLIP 22378787,21685362,22109552 0004,0096,0004 LC UBE2D1 MYLIP 21734303,21685362,21685362 0096,0114,0096 LC MYLIP MYLIP 21685362,21685362,21685362,12826659 0004,0415,0114,0096 LC LDLR MYLIP 26666640,23382078,21734303,21734303 0004,0428,0004,0415 LC UBC MYLIP 22378787,21685362,22109552 0004,0096,0004 LC UBE2D1 MYLIP 21734303,21685362,21685362 0096,0114,0096 LC MYLIP MYLIP 21685362,21685362,21685362,12826659 0004,0415,0114,0096 LC MYL12B MYLIP 10593918,10593918 0004,0018 LC KDM1A MYLIP 23455924 0018 HT LDLR MYLIP 21685362,21734303,21734303 0415,0004,0415 LC CRK MYLIP 25814554,25814554,25814554 0397,0018,1356 HT UBE2D1 MYLIP 21685362,21685362 0114,0096 LC SRPK2 MYLIP 26167880 0415 LC MTAP MYLIP 12826659,12826659 0018,0019 LC LNX2 MYLIP 21516116 0018 HT MIPOL1 MYLIP 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT RASSF5 MYLIP 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT MYLIP MYLIP 21685362,21685362,21685362 0004,0415,0114 LC MYLIP DAPP1 25814554,25814554,25814554 0397,0018,1356 HT MYLIP CNPY2 12826659,12826659,12826659 0004,0018,0096 LC MYLIP TSC22D4 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8WY64 O75604 MYLIP USP2 0.21 26666640 Q8WY64 P01130 MYLIP LDLR 0.82 21734303,23382078,21685362,26666640,22109552 Q8WY64 B2RXF5 MYLIP ZBTB42 0.236 unassigned1304 Q8WY64 J3KQ70 MYLIP INO80B-WBP1 {ECO:0000313|ENSEMBL:ENSP00000388677} 0.236 unassigned1304 Q8WY64 O00560 MYLIP SDCBP 0.236 unassigned1304 Q8WY64 O14558 MYLIP HSPB6 0.236 unassigned1304 Q8WY64 O14950 MYLIP MYL12B 0.454 10593918 Q8WY64 O60341 MYLIP KDM1A 0.332 23455924 Q8WY64 P55771 MYLIP PAX9 0.236 unassigned1304 Q8WY64 Q03989 MYLIP ARID5A 0.236 unassigned1304 Q8WY64 Q05516 MYLIP ZBTB16 0.236 unassigned1304 Q8WY64 Q5JST6 MYLIP EFHC2 0.236 unassigned1304 Q8WY64 Q5T7N3 MYLIP KANK4 0.236 unassigned1304 Q8WY64 Q6NSM0 MYLIP Q6NSM0 0.236 unassigned1304 Q8WY64 Q6UY14 MYLIP ADAMTSL4 0.236 unassigned1304 Q8WY64 Q86UR1 MYLIP NOXA1 0.236 unassigned1304 Q8WY64 Q86WV8 MYLIP Q86WV8 0.236 unassigned1304 Q96D03 Q8WY64 DDIT4L MYLIP 0.236 unassigned1304 Q96ED9 Q8WY64 HOOK2 MYLIP 0.236 unassigned1304 Q96IK5 Q8WY64 GMCL1 MYLIP 0.236 unassigned1304 Q99592 Q8WY64 ZBTB18 MYLIP 0.236 unassigned1304 Q9Y2B0 Q8WY64 CNPY2 MYLIP 0.454 12826659 Q8WY64 Q8WY64 MYLIP MYLIP 0.61 21685362,12826659 Q8WY64 P51668 MYLIP UBE2D1 0.671 21685362,21734303 Q9Y3Q8 Q8WY64 TSC22D4 MYLIP 0.454 25416956 Q8WY64 Q8WWW0 MYLIP RASSF5 0.454 25416956 Q8WY64 Q8TD10 MYLIP MIPOL1 0.454 25416956 Q9Y2X8 Q8WY64 UBE2D4 MYLIP 0.309 21685362 Q8WY64 P61088 MYLIP UBE2N 0.309 21734303 Q8WY64 P61077 MYLIP UBE2D3 0.309 21685362 Q8WY64 Q14114 MYLIP LRP8 0.309 22109552 Q8WY64 P62837 MYLIP UBE2D2 0.309 21685362 Q8WY64 P98155 MYLIP VLDLR 0.454 21734303,22109552 Q8WY64 Q8N448 MYLIP LNX2 0.332 21516116 Q9UN19 Q8WY64 DAPP1 MYLIP 0.376 25814554 Q8WY64 P46108 MYLIP CRK 0.376 25814554 Q8WY64 P78362 MYLIP SRPK2 0.183 26167880

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 MYL12B MYLIP MI:0045 experimental interaction detection MI:0461 interaction database SIAH2 MYLIP MI:0362 inference MI:1106 pathways database KDM1A MYLIP MI:0045 experimental interaction detection MI:0461 interaction database USP2 MYLIP MI:0045 experimental interaction detection MI:0461 interaction database FBXO21 MYLIP MI:0362 inference MI:1106 pathways database LDLR MYLIP MI:0045 experimental interaction detection MI:0461 interaction database UBB MYLIP MI:0362 inference MI:1106 pathways database UBC MYLIP MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database MYL12A MYLIP MI:0362 inference MI:0461 interaction database TRIM21 MYLIP MI:0362 inference MI:1106 pathways database CCNF MYLIP MI:0362 inference MI:1106 pathways database CRK MYLIP MI:0045 experimental interaction detection MI:0461 interaction database UBE2A MYLIP MI:0362 inference MI:1106 pathways database UBE2D1 MYLIP MI:0045 experimental interaction detection MI:0461 interaction database FBXW4 MYLIP MI:0362 inference MI:1106 pathways database UBE2D3 MYLIP MI:0045 experimental interaction detection MI:0461 interaction database UBE2N MYLIP MI:0045 experimental interaction detection MI:0461 interaction database UBE2D2 MYLIP MI:0045 experimental interaction detection MI:0461 interaction database RBX1 MYLIP MI:0362 inference MI:1106 pathways database RPS27A MYLIP MI:0362 inference MI:1106 pathways database UBA52 MYLIP MI:0362 inference MI:1106 pathways database SKP1 MYLIP MI:0362 inference MI:1106 pathways database SRPK2 MYLIP MI:0045 experimental interaction detection MI:0461 interaction database VLDLR MYLIP MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SKP2 MYLIP MI:0362 inference MI:1106 pathways database CUL1 MYLIP MI:0362 inference MI:1106 pathways database LRP8 MYLIP MI:0362 inference MI:0461 interaction database TRIP12 MYLIP MI:0362 inference MI:1106 pathways database LONRF1 MYLIP MI:0362 inference MI:1106 pathways database HECTD2 MYLIP MI:0362 inference MI:1106 pathways database FBXO31 MYLIP MI:0362 inference MI:1106 pathways database FBXW9 MYLIP MI:0362 inference MI:1106 pathways database FBXW10 MYLIP MI:0362 inference MI:1106 pathways database RNF213 MYLIP MI:0362 inference MI:1106 pathways database FBXL22 MYLIP MI:0362 inference MI:1106 pathways database FBXL19 MYLIP MI:0362 inference MI:1106 pathways database FBXW12 MYLIP MI:0362 inference MI:1106 pathways database RNF19B MYLIP MI:0362 inference MI:1106 pathways database RNF144B MYLIP MI:0362 inference MI:1106 pathways database RBBP6 MYLIP MI:0362 inference MI:1106 pathways database HUWE1 MYLIP MI:0362 inference MI:1106 pathways database TRIM69 MYLIP MI:0362 inference MI:1106 pathways database SIAH1 MYLIP MI:0362 inference MI:1106 pathways database HERC6 MYLIP MI:0362 inference MI:1106 pathways database UBR2 MYLIP MI:0362 inference MI:1106 pathways database FBXL14 MYLIP MI:0362 inference MI:1106 pathways database FBXW8 MYLIP MI:0362 inference MI:1106 pathways database LNX2 MYLIP MI:0045 experimental interaction detection MI:0461 interaction database FBXL16 MYLIP MI:0362 inference MI:1106 pathways database FBXO15 MYLIP MI:0362 inference MI:1106 pathways database ZNRF1 MYLIP MI:0362 inference MI:1106 pathways database FBXL13 MYLIP MI:0362 inference MI:1106 pathways database FBXO22 MYLIP MI:0362 inference MI:1106 pathways database ZNRF2 MYLIP MI:0362 inference MI:1106 pathways database FBXO27 MYLIP MI:0362 inference MI:1106 pathways database FBXO30 MYLIP MI:0362 inference MI:1106 pathways database RNF217 MYLIP MI:0362 inference MI:1106 pathways database MIPOL1 MYLIP MI:0045 experimental interaction detection MI:0461 interaction database DTX3L MYLIP MI:0362 inference MI:1106 pathways database FBXO41 MYLIP MI:0362 inference MI:1106 pathways database LMO7 MYLIP MI:0362 inference MI:1106 pathways database RASSF5 MYLIP MI:0045 experimental interaction detection MI:0461 interaction database MYLIP FBXW7 MI:0362 inference MI:1106 pathways database MYLIP FBXO32 MI:0362 inference MI:1106 pathways database MYLIP FBXW5 MI:0362 inference MI:1106 pathways database MYLIP MIB2 MI:0362 inference MI:1106 pathways database MYLIP SPSB1 MI:0362 inference MI:1106 pathways database MYLIP FBXL8 MI:0362 inference MI:1106 pathways database MYLIP FBXO17 MI:0362 inference MI:1106 pathways database MYLIP FBXL20 MI:0362 inference MI:1106 pathways database MYLIP FBXL18 MI:0362 inference MI:1106 pathways database MYLIP NEDD4L MI:0362 inference MI:1106 pathways database MYLIP RBCK1 MI:0362 inference MI:1106 pathways database MYLIP FBXL15 MI:0362 inference MI:1106 pathways database MYLIP FBXO44 MI:0362 inference MI:1106 pathways database MYLIP UNKL MI:0362 inference MI:1106 pathways database MYLIP SMURF2 MI:0362 inference MI:1106 pathways database MYLIP TRIM36 MI:0362 inference MI:1106 pathways database MYLIP FBXO6 MI:0362 inference MI:1106 pathways database MYLIP RNF19A MI:0362 inference MI:1106 pathways database MYLIP RLIM MI:0362 inference MI:1106 pathways database MYLIP FBXL12 MI:0362 inference MI:1106 pathways database MYLIP FBXO40 MI:0362 inference MI:1106 pathways database MYLIP HERC5 MI:0362 inference MI:1106 pathways database MYLIP FBXL7 MI:0362 inference MI:1106 pathways database MYLIP FBXO2 MI:0362 inference MI:1106 pathways database MYLIP FBXO10 MI:0362 inference MI:1106 pathways database MYLIP FBXO9 MI:0362 inference MI:1106 pathways database MYLIP FBXL5 MI:0362 inference MI:1106 pathways database MYLIP FBXL4 MI:0362 inference MI:1106 pathways database MYLIP FBXW11 MI:0362 inference MI:1106 pathways database MYLIP FBXO4 MI:0362 inference MI:1106 pathways database MYLIP FBXL21 MI:0362 inference MI:1106 pathways database MYLIP FBXL3 MI:0362 inference MI:1106 pathways database MYLIP FBXW2 MI:0362 inference MI:1106 pathways database MYLIP DAPP1 MI:0045 experimental interaction detection MI:0461 interaction database MYLIP BTRC MI:0362 inference MI:1106 pathways database MYLIP CNPY2 MI:0045 experimental interaction detection MI:0461 interaction database MYLIP UBE2D4 MI:0045 experimental interaction detection MI:0461 interaction database MYLIP FBXO7 MI:0362 inference MI:1106 pathways database MYLIP TSC22D4 MI:0045 experimental interaction detection MI:0461 interaction database MYLIP RNF115 MI:0362 inference MI:1106 pathways database MYLIP RNF114 MI:0362 inference MI:1106 pathways database MYLIP WSB1 MI:0362 inference MI:1106 pathways database