BTK
PTM - CPLM
Gene NameUniProt IDTypePositionCode
BTK; AGMX1; ATK; BPKQ06187Ubiquitination322K
BTK; AGMX1; ATK; BPKQ06187Ubiquitination406K
BTK; AGMX1; ATK; BPKQ06187Ubiquitination536K
PTM - dbPAF
Gene NameUniProt IDPositionTypeSpecies
BTK; AGMX1; ATK; BPKQ06187115SHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187179SHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187180SHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187184THomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187191THomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ0618720THomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ0618721SHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187223YHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187225YHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187263YHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187279YHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187309SHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187310SHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187318SHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187323SHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187334YHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187342SHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187344YHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187345YHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187361YHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187366SHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187371SHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187375YHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187378SHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ0618740YHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187461YHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187495THomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ0618751SHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187511YHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187543SHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ0618755SHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187551YHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187552THomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187553SHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187564SHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187602THomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187604SHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187617YHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187623SHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ06187659SHomo sapiens(Human)
BTK; AGMX1; ATK; BPKQ0618793SHomo sapiens(Human)
PTM - PhosphositePlus
UniProt IDMOD_RSDTypeSITE_+/-7_AA
Q06187K183-acAcetylationKPGssHRktKKPLPP
Q06187S21-pPhosphorylationSQQKKKTsPLNFKKR
Q06187Y40-pPhosphorylationTVHKLSYyEYDFERG
Q06187S51-pPhosphorylationFERGRRGsKKGsIDV
Q06187S55-pPhosphorylationRRGsKKGsIDVEKIT
Q06187S93-pPhosphorylationSSEMEQIsIIERFPY
Q06187S179-pPhosphorylationNGSLKPGssHRktKK
Q06187S180-pPhosphorylationGSLKPGssHRktKKP
Q06187T184-pPhosphorylationPGssHRktKKPLPPt
Q06187T191-pPhosphorylationtKKPLPPtPEEDQIL
Q06187Y223-pPhosphorylationLKKVVALyDyMPMNA
Q06187Y225-pPhosphorylationKVVALyDyMPMNAND
Q06187Y263-pPhosphorylationDKNGQEGyIPSNYVT
Q06187Y279-pPhosphorylationAEDSIEMyEWYSKHM
Q06187S318-pPhosphorylationKAGKYTVsVFAkSTG
Q06187Y334-pPhosphorylationPQGVIRHyVVCSTPQ
Q06187S342-pPhosphorylationVVCSTPQsQyyLAEK
Q06187Y344-pPhosphorylationCSTPQsQyyLAEKHL
Q06187Y345-pPhosphorylationSTPQsQyyLAEKHLF
Q06187Y361-pPhosphorylationTIPELINyHQHNsAG
Q06187S366-pPhosphorylationINyHQHNsAGLIsRL
Q06187S371-pPhosphorylationHNsAGLIsRLKyPVs
Q06187Y375-pPhosphorylationGLIsRLKyPVsQQNK
Q06187S378-pPhosphorylationsRLKyPVsQQNKNAP
Q06187Y461-pPhosphorylationHEKLVQLyGVCTkQR
Q06187T495-pPhosphorylationEMRHRFQtQQLLEMC
Q06187S543-pPhosphorylationkVSDFGLsRYVLDDE
Q06187Y551-pPhosphorylationRYVLDDEytsSVGSk
Q06187T552-pPhosphorylationYVLDDEytsSVGSkF
Q06187S553-pPhosphorylationVLDDEytsSVGSkFP
Q06187S564-pPhosphorylationSkFPVRWsPPEVLMY
Q06187T602-pPhosphorylationKMPYERFtNsETAEH
Q06187S604-pPhosphorylationPYERFtNsETAEHIA
Q06187S659-pPhosphorylationLDVMDEEs_______
Q06187K300-ubUbiquitinationQLLKQEGkEGGFIVR
Q06187K322-ubUbiquitinationYTVsVFAkSTGDPQG
Q06187K406-ubUbiquitinationPKDLTFLkELGTGQF
Q06187K466-ubUbiquitinationQLyGVCTkQRPIFII
Q06187K536-ubUbiquitinationVNDQGVVkVSDFGLs
Q06187K558-ubUbiquitinationytsSVGSkFPVRWsP
PTM - dbPTM
UniProt IDPositionCodeTypeResourcesReferences
Q0618720TPhosphorylationSwiss-Prot 101071119369195
Q0618721SPhosphorylationSwiss-Prot 101071116644721;19369195
Q0618755SPhosphorylationSwiss-Prot 101071119369195
Q06187115SPhosphorylationSwiss-Prot 101071116644721
Q06187179SPhosphorylationSwiss-Prot 101071119369195
Q06187180SPhosphorylationSwiss-Prot 101071111598012;19369195
Q06187191TPhosphorylationSwiss-Prot 101071119369195
Q06187223YPhosphorylationSwiss-Prot 10107118630736;9012831;12573241;17932028;19369195
Q06187309SPhosphorylationSwiss-Prot 101071119369195
Q06187323SPhosphorylationSwiss-Prot 101071119369195
Q06187342SPhosphorylationSwiss-Prot 101071119369195
Q06187361YPhosphorylationSwiss-Prot 101071119369195
Q06187375YPhosphorylationSwiss-Prot 101071119369195
Q06187551YPhosphorylationSwiss-Prot 10107118630736;9012831;18083107;19369195
Q06187602TPhosphorylationSwiss-Prot 101071119369195
Q06187604SPhosphorylationSwiss-Prot 101071119369195
Q06187617YPhosphorylationSwiss-Prot 101071115375214
Q06187623SPhosphorylationSwiss-Prot 101071115375214
Q06187659SPhosphorylationSwiss-Prot 101071119369195
Q061872AAcetylationSwiss-Prot 1010711-
Q06187223YPhosphorylationPhosphoELM.1001112573241;12445832;8630736
Q06187551YPhosphorylationPhosphoELM.1001118083107;8630736;8630736
Q06187322KUbiquitylationPhosphositeplus.101073021890473
Q06187406KUbiquitylationPhosphositeplus.101073021890473;21906983
Q06187536KUbiquitylationPhosphositeplus.101073021906983
Q06187179SPhosphorylationPhosphositeplus.101073020164059
Q06187180SPhosphorylationPhosphositeplus.101073019369195;20164059
Q0618721SPhosphorylationPhosphositeplus.101073019369195
Q06187342SPhosphorylationPhosphositeplus.101073019369195
Q06187543SPhosphorylationPhosphositeplus.101073019369195
Q0618755SPhosphorylationPhosphositeplus.101073019369195
Q06187604SPhosphorylationPhosphositeplus.101073019369195
Q06187659SPhosphorylationPhosphositeplus.101073019369195
Q06187191TPhosphorylationPhosphositeplus.101073019369195
Q06187602TPhosphorylationPhosphositeplus.101073019369195
Q06187223YPhosphorylationPhosphositeplus.101073010051622;12445832;12573241;14597636;14656219;16464493;16497976;17239630;17360941;17932028;19369195;21394647;21403953;21441935;21447384;8630736;9188445;9326643
Q06187225YPhosphorylationPhosphositeplus.101073016497976;17360941;21394647
Q06187344YPhosphorylationPhosphositeplus.101073017360941;21394647
Q06187361YPhosphorylationPhosphositeplus.101073016497976;17360941;19369195
Q06187375YPhosphorylationPhosphositeplus.101073019369195;21394647
Q06187511YPhosphorylationPhosphositeplus.101073018083107
Q06187551YPhosphorylationPhosphositeplus.101073010051622;11226282;11413148;12445832;14597636;14656219;17264076;17360941;18083107;19369195;21394647;21403953;21441935;21447384;21482705;21659545;22115753;8629002;8630736;9188445;9326643
Q06187225YPhosphorylationHPRD 9.016497976
Q06187361YPhosphorylationHPRD 9.016497976
Q06187617YPhosphorylationHPRD 9.015375214
Q06187223YPhosphorylation (ABL1)HPRD 9.012445832,8630736,11598012,8629002,12573241,16497976
Q06187223YPhosphorylation (BTK)HPRD 9.012445832,8630736,11598012,8629002,12573241,16497976
Q06187180SPhosphorylation (PRKCB)HPRD 9.011598012
Q06187223YPhosphorylation (ITK)HPRD 9.012445832,8630736,11598012,8629002,12573241,16497976
Q06187551YPhosphorylation (LYN)HPRD 9.011226282,11598012,8629002,8630736
Q06187551YPhosphorylation (SYK)HPRD 9.011226282,11598012,8629002,8630736
Q06187223YPhosphorylation (TEC)HPRD 9.012445832,8630736,11598012,8629002,12573241,16497976
PTM - HPRD
SymbolPositionCodeTypeReferences
BTK180SPhosphorylation11598012
BTK223YPhosphorylation12445832,8630736,11598012,8629002,12573241,16497976
BTK225YPhosphorylation16497976
BTK361YPhosphorylation16497976
BTK551YPhosphorylation11226282,11598012,8629002,8630736
BTK617YPhosphorylation15375214
PTM - Phospho.ELM
UniProtPositionCodePMIDsKinaseSourceType
Q06187551Y18083107HTPPhosphorylation
Q06187551Y8630736LynLTPPhosphorylation
Q06187551Y8630736BTKLTPPhosphorylation
Q06187223Y12573241LTPPhosphorylation
Q06187223Y12445832AblLTPPhosphorylation
Q06187223Y8630736BTKLTPPhosphorylation
PTM - UniProt
UniProt IDPositionTypePMIDs
Q061872N-acetylalanine25944712
Q0618721Phosphoserine16644721
Q0618755Phosphoserine19369195
Q06187115Phosphoserine16644721
Q06187180Phosphoserine; by PKC/PRKCB11598012
Q06187191Phosphothreonine19369195;23186163
Q06187223Phosphotyrosine; by autocatalysis23186163;12573241;17932028;8630736;9012831
Q06187361Phosphotyrosine19369195
Q06187551Phosphotyrosine; by LYN and SYK8630736;9012831
Q06187604Phosphoserine23186163
Q06187617Phosphotyrosine15375214
Q06187623Phosphoserine15375214
Q06187659Phosphoserine19369195
PTM - PHOSIDA
SymbolAccessionCodePositionSurrounding SequenceType
BTKIPI00029132Y551VLDDEYpTSSVGSKphosphorylation
PTM - BioGRID
Entrez GeneBioGRID IDPositionCodeTypePMIDs
695107160-KUbiquitination21890473
695107160-KUbiquitination21906983
PTM - mUbiSiDa
Gene NameSpeciesUbiquitination SiteUbiquitination SequenceEvidence PMID
BTKHomo sapiens (Human)322; 406"322,TVSVFAKSTGDPQ; 406,KDLTFLKELGTGQ"322:21890473; 406:21890473
BTKHomo sapiens (Human)322; 406"322,TVSVFAKSTGDPQ; 406,KDLTFLKELGTGQ"322:21890473; 406:21890473
BTKHomo sapiens (Human)322; 406"322,TVSVFAKSTGDPQ; 406,KDLTFLKELGTGQ""322:21890473; 406:21906983,21890473"
BTKHomo sapiens (Human)322; 406"322,TVSVFAKSTGDPQ; 406,KDLTFLKELGTGQ"322:21890473; 406:21890473
BTKHomo sapiens (Human)322; 406"322,TVSVFAKSTGDPQ; 406,KDLTFLKELGTGQ"322:21890473; 406:21890473
BTKHomo sapiens (Human)322"322,TVSVFAKSTGDPQ"322:21890473
BTKHomo sapiens (Human)322; 406"322,TVSVFAKSTGDPQ; 406,KDLTFLKELGTGQ"322:21890473; 406:21890473
BTKHomo sapiens (Human)322"322,TVSVFAKSTGDPQ"322:21890473
BTKHomo sapiens (Human)322; 406"322,TVSVFAKSTGDPQ; 406,KDLTFLKELGTGQ"322:21890473; 406:21890473
BTKHomo sapiens (Human)322; 406"322,TVSVFAKSTGDPQ; 406,KDLTFLKELGTGQ"322:21890473; 406:21890473
BTKHomo sapiens (Human)37; 121"37,TVSVFAKSTGDPQ; 121,KDLTFLKELGTGQ"37:21890473; 121:21890473
BTKHomo sapiens (Human)37; 121"37,TVSVFAKSTGDPQ; 121,KDLTFLKELGTGQ"37:21890473; 121:21890473
BTKHomo sapiens (Human)37; 121"37,TVSVFAKSTGDPQ; 121,KDLTFLKELGTGQ"37:21890473; 121:21890473
BTKHomo sapiens (Human)322; 360"322,TVSVFAKSTGDPQ; 360,NDQGVVKVSDFGL"322:21890473; 360:21906983
BTKHomo sapiens (Human)37; 121"37,TVSVFAKSTGDPQ; 121,KDLTFLKELGTGQ"37:21890473; 121:21890473
BTKHomo sapiens (Human)37"37,TVSVFAKSTGDPQ"37:21890473
BTKHomo sapiens (Human)37"37,TVSVFAKSTGDPQ"37:21890473
BTKHomo sapiens (Human)37"37,TVSVFAKSTGDPQ"37:21890473
BTKHomo sapiens (Human)322; 406"322,TVSVFAKSTGDPQ; 406,KDLTFLKELGTGQ"322:21890473; 406:21890473
BTKHomo sapiens (Human)37; 121"37,TVSVFAKSTGDPQ; 121,KDLTFLKELGTGQ"37:21890473; 121:21890473
BTKHomo sapiens (Human)37"37,TVSVFAKSTGDPQ"37:21890473
BTKHomo sapiens (Human)322; 77; 406"322,TVSVFAKSTGDPQ; 77,KDLTFLKELGTGQ; 406,KDLTFLKELGTGQ"322:21890473; 77:21906983; 406:21890473
BTKHomo sapiens (Human)37; 121"37,TVSVFAKSTGDPQ; 121,KDLTFLKELGTGQ"37:21890473; 121:21890473
BTKHomo sapiens (Human)322; 406; 536"322,TVSVFAKSTGDPQ; 406,KDLTFLKELGTGQ; 536,NDQGVVKVSDFGL""322:21890473; 406:21890473,21906983; 536:21906983"