| Tyrosine-protein kinase BTK | Successful target | Bruton's tyrosine kinase;BPK;Agammaglobulinaemia tyrosine kinase;ATK;B cell progenitor kinase | Acute lymphoblastic leukaemia;B-cell immunodeficiency | AVL-292;AVL-292;AVL-292;AVL-292;AVL-292;AVL-292;Ibrutinib companion diagnostic;ACP-319;CC-292;ACP-196;Ibrutinib;Ibrutinib;Ibrutinib;ONO-4059 | Ibrutinib companion diagnostic;ACP-319;GDC-0834;compound 38;Inositol 1,3,4,5-Tetrakisphosphate;ACP-196;compound 2c;compound 31;PCI-45292;RN486;Ibrutinib;CGI-1316;LFM-A13 | |