PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus UBA6 UBE2Z 17597759,24528925,20975683,22427669,19250909 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 PYGB 22863883 biogrid exp G G G G G G G G G G G G G G P UBA6 CTPS1 26344197,22863883 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 UBE4B 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 NUP188 26344197 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 ELAVL1 19322201 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 EIF4A3 26496610 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 C1orf123 26344197 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBA6 H2AFV 22863883 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 PFKP 26344197 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 OXSR1 22863883 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 UBE2G2 17597759 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 GNPDA1 22863883 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 AIPL1 22347407 biogrid exp G G G G G G G G G G G G G G G G G G G G G G UBA6 HMBOX1 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 SMAD9 15231748 hprd,biogrid,i2d,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 LIMD1 22863883 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBA6 UCHL3 26344197,22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 TWF2 22863883 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 MBD5 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 TRNT1 22863883 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 CCDC8 24711643 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 ENOPH1 26344197 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 SERPINB5 26186194 biogrid exp G G G G G G G GP UBA6 HDLBP 26344197,22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 FMR1 26496610 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 STRAP 26344197 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 VPS26B 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 NPEPPS 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 ATG7 26344197 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 ARHGAP25 26186194 biogrid exp G G G G G G G G G G G G G P G UBA6 DIAPH1 26344197 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 UBE2T 17597759 biogrid exp G G G G G G G G G G G GP G UBA6 FXR1 26496610 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 FKBP9 22863883 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 IMPDH2 26344197 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 DYNLT1 26344197 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBA6 NTRK1 25921289 biogrid exp G P UBA6 HEXA 22863883 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 EHD1 22863883 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 MTRR 26344197 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 SMS 26344197 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 UBE2D3 17597759 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 TSN 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 UBE2S 17597759 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 UBE2L6 19250909 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 XPNPEP1 22863883 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 AHCYL1 22863883 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBA6 UBE2D1 17597759 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 NUBP2 22863883 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 SNF8 26344197 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 FYTTD1 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 NUP93 26344197 biogrid exp G G G G G G G G G G G G G G GP UBA6 UBE2D2 17597759,17580310,19250909 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 UBE2L3 17597759,19250909 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 UBC 17550899,22427669,23003343 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 PGGT1B 22863883 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 OGFOD1 22863883 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 OR5F1 26186194 biogrid exp UBA6 NOL3 22863883 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G P G UBA6 PDCD6IP 22863883 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 CLUH 26344197 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBA6 USP48 26344197,22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 RAD23B 22863883, 23023127 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 UBA52 17597759, 16082366 dip exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 UBD 20975683,22427669, 16082366 biogrid exp, pred P UBA6 RAD23A 22863883, 23023127 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 EED ortho G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 YWHAE ortho G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 YWHAH ortho G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 Ubiquitin C variant 16082366 pred UBA6 UHRF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 USP14 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 UBC 23023127 pred UBA6 NAE1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 SAE1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 PARK2 23023127 pred G G G G G G G G G G G G G G G GP G UBA6 UBA2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 UBTD2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 UBA3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 UBE2I 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 SUMO1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 SUMO2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 NSFL1C 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 UBE2R2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBA6 AXIN1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 IKBKB 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 UBL4A 23023127, 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G P G UBA6 NEDD8 23023127, 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 UBXN2B 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 SUMO3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 UBA7 23023127 pred P UBA6 UBQLN1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G GP G UBA6 UBQLN3 16082366 pred G G G G G G GP G

PPI - HINT Gene A Gene B PMID Method Quality UBA6 AHCYL1 22863883 0401 HT UBA6 NOL3 22863883 0401 HT UBA6 CLUH 26344197 0401 HT UBA6 UBE4B 22939629 0401 HT UBA6 OR5F1 26186194 0004 HT UBA6 FKBP9 22863883 0401 HT UBA6 ATG7 26344197 0401 HT UBA6 OXSR1 22863883 0401 HT UBA6 HEXA 22863883 0401 HT UBA6 UBC 17597759,17550899,17597759,17580310,22427669,17597759,22427669,20639865 0808,0004,0007,0004,0096,0096,0415,0004 LC UBA6 PYGB 22863883 0401 HT UBA6 IMPDH2 26344197 0401 HT UBA6 UCHL3 26344197,22939629 0401,0401 HT UBA6 CTPS1 26344197,22863883 0401,0401 HT UBA6 SERPINB5 26186194 0004 HT UBA6 EIF4A3 26496610,26496610 0007,0004 HT UBA6 GNPDA1 22863883 0401 HT UBA6 FXR1 26496610,26496610 0007,0004 HT UBA6 SMS 26344197 0401 HT UBA6 PGGT1B 22863883 0401 HT UBA6 RAD23A 22863883 0401 HT UBA6 RAD23B 22863883 0401 HT UBA6 NPEPPS 22939629 0401 HT UBA6 UBE2D2 17580310,17597759 0096,0096 LC UBA6 DYNLT1 26344197 0401 HT UBA6 HDLBP 26344197,22939629 0401,0401 HT UBA6 PFKP 26344197 0401 HT UBA6 FMR1 26496610,26496610 0007,0004 HT UBA6 TSN 22939629 0401 HT UBA6 VPS26B 22939629 0401 HT UBA6 NUP188 26344197 0401 HT UBA6 TWF2 22863883 0401 HT UBA6 Q6URC4 26344197 0401 HT UBA6 H2AFV 22863883 0401 HT UBA6 USP48 26344197,22939629 0401,0401 HT UBA6 NUP93 26344197 0401 HT UBA6 OGFOD1 22863883 0401 HT UBA6 PDCD6IP 22863883 0401 HT UBA6 SNF8 26344197 0401 HT UBA6 TRNT1 22863883 0401 HT UBA6 FYTTD1 26186194 0004 HT UBA6 EHD1 22863883 0401 HT UBA6 XPNPEP1 22863883 0401 HT UBA6 C1ORF123 26344197 0401 HT UBA6 MBD5 26186194 0004 HT UBA6 MTRR 26344197 0401 HT UBA6 LIMD1 22863883 0401 HT UBA6 ENOPH1 26344197 0401 HT UBA6 STRAP 26344197 0401 HT UBA6 NUBP2 22863883 0401 HT UBA6 HEL-S-308 26186194 0004 HT UBA6 AHCYL1 22863883 0401 HT UBA6 NOL3 22863883 0401 HT UBA6 CLUH 26344197 0401 HT UBA6 UBE4B 22939629 0401 HT UBA6 OR5F1 26186194 0004 HT UBA6 FKBP9 22863883 0401 HT UBA6 ATG7 26344197 0401 HT UBA6 OXSR1 22863883 0401 HT UBA6 HEXA 22863883 0401 HT UBA6 PYGB 22863883 0401 HT UBA6 IMPDH2 26344197 0401 HT UBA6 UCHL3 26344197,22939629 0401,0401 HT UBA6 CTPS1 26344197,22863883 0401,0401 HT UBA6 SERPINB5 26186194 0004 HT UBA6 EIF4A3 26496610,26496610 0007,0004 HT UBA6 GNPDA1 22863883 0401 HT UBA6 FXR1 26496610,26496610 0007,0004 HT UBA6 SMS 26344197 0401 HT UBA6 PGGT1B 22863883 0401 HT UBA6 RAD23A 22863883 0401 HT UBA6 RAD23B 22863883 0401 HT UBA6 NPEPPS 22939629 0401 HT UBA6 DYNLT1 26344197 0401 HT UBA6 HDLBP 26344197,22939629 0401,0401 HT UBA6 PFKP 26344197 0401 HT UBA6 FMR1 26496610,26496610 0007,0004 HT UBA6 TSN 22939629 0401 HT UBA6 VPS26B 22939629 0401 HT UBA6 NUP188 26344197 0401 HT UBA6 TWF2 22863883 0401 HT UBA6 Q6URC4 26344197 0401 HT UBA6 H2AFV 22863883 0401 HT UBA6 USP48 26344197,22939629 0401,0401 HT UBA6 NUP93 26344197 0401 HT UBA6 OGFOD1 22863883 0401 HT UBA6 PDCD6IP 22863883 0401 HT UBA6 SNF8 26344197 0401 HT UBA6 TRNT1 22863883 0401 HT UBA6 FYTTD1 26186194 0004 HT UBA6 EHD1 22863883 0401 HT UBA6 XPNPEP1 22863883 0401 HT UBA6 C1ORF123 26344197 0401 HT UBA6 MBD5 26186194 0004 HT UBA6 MTRR 26344197 0401 HT UBA6 LIMD1 22863883 0401 HT UBA6 ENOPH1 26344197 0401 HT UBA6 STRAP 26344197 0401 HT UBA6 NUBP2 22863883 0401 HT UBA6 HEL-S-308 26186194 0004 HT UBA6 UBC 17597759,17550899,17597759,17580310,22427669,17597759,22427669,20639865 0808,0004,0007,0004,0096,0096,0415,0004 LC UBA6 UBE2D2 17580310,17597759 0096,0096 LC UBA6 UBE2L6 19250909 0415 LC UBA6 SMAD9 15231748 0018 HT UBA6 UBD 22427669,22427669,20975683 0415,0096,0018 LC UBA6 AHCYL1 22863883 0401 LC UBA6 NOL3 22863883 0401 LC UBA6 CLUH 26344197 0401 LC UBA6 UBE4B 22939629 0401 LC UBA6 FKBP9 22863883 0401 LC UBA6 ATG7 26344197 0401 LC UBA6 OXSR1 22863883 0401 LC UBA6 HEXA 22863883 0401 LC UBA6 UBC 17597759,17597759,22427669,17597759,22427669 0808,0007,0096,0096,0415 LC UBA6 PYGB 22863883 0401 LC UBA6 IMPDH2 26344197 0401 LC UBA6 UCHL3 26344197,22939629 0401,0401 LC UBA6 CTPS1 26344197,22863883 0401,0401 LC UBA6 GNPDA1 22863883 0401 LC UBA6 SMS 26344197 0401 LC UBA6 PGGT1B 22863883 0401 LC UBA6 RAD23A 22863883 0401 LC UBA6 RAD23B 22863883 0401 LC UBA6 NPEPPS 22939629 0401 LC UBA6 UBE2D2 19250909 0415 LC UBA6 DYNLT1 26344197 0401 LC UBA6 UBE2L3 19250909 0415 LC UBA6 HDLBP 26344197,22939629 0401,0401 LC UBA6 PFKP 26344197 0401 LC UBA6 TSN 22939629 0401 LC UBA6 VPS26B 22939629 0401 LC UBA6 NUP188 26344197 0401 LC UBA6 TWF2 22863883 0401 LC UBA6 HMBOX1 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT UBA6 Q6URC4 26344197 0401 LC UBA6 H2AFV 22863883 0401 LC UBA6 USP48 26344197,22939629 0401,0401 LC UBA6 NUP93 26344197 0401 LC UBA6 OGFOD1 22863883 0401 LC UBA6 PDCD6IP 22863883 0401 LC UBA6 SNF8 26344197 0401 LC UBA6 TRNT1 22863883 0401 LC UBA6 EHD1 22863883 0401 LC UBA6 UBE2Z 20975683,24528925,22427669,19250909,20975683 0018,0415,0415,0415,0415 LC UBA6 XPNPEP1 22863883 0401 LC UBA6 C1ORF123 26344197 0401 LC UBA6 MTRR 26344197 0401 LC UBA6 LIMD1 22863883 0401 LC UBA6 ENOPH1 26344197 0401 LC UBA6 STRAP 26344197 0401 LC UBA6 NUBP2 22863883 0401 LC

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 UBA6 UBE2L6 MI:0045 experimental interaction detection MI:0461 interaction database UBA6 SMAD9 MI:0045 experimental interaction detection MI:0461 interaction database UBA6 UBD MI:0045 experimental interaction detection MI:0461 interaction database UBA6 EED MI:0362 inference MI:0461 interaction database UBA6 OR5F1 MI:0045 experimental interaction detection MI:0461 interaction database UBA6 NTRK1 MI:0045 experimental interaction detection MI:0461 interaction database UBA6 UBB MI:0362 inference MI:0461 interaction database UBA6 UBC MI:0045 experimental interaction detection MI:0461 interaction database UBA6 UBA1 MI:0362 inference MI:0461 interaction database UBA6 SERPINB5 MI:0045 experimental interaction detection MI:0461 interaction database UBA6 EIF4A3 MI:0045 experimental interaction detection MI:0461 interaction database UBA6 ARHGAP25 MI:0045 experimental interaction detection MI:0461 interaction database UBA6 UBE2A MI:0362 inference MI:0461 interaction database UBA6 FXR1 MI:0045 experimental interaction detection MI:0461 interaction database UBA6 UBE2D1 MI:0045 experimental interaction detection MI:0461 interaction database UBA6 UBE2G2 MI:0045 experimental interaction detection MI:0461 interaction database UBA6 UBE2D3 MI:0045 experimental interaction detection MI:0461 interaction database UBA6 YWHAG MI:0362 inference MI:0461 interaction database UBA6 UBE2D2 MI:0045 experimental interaction detection MI:0461 interaction database UBA6 RPS27A MI:0362 inference MI:0461 interaction database UBA6 UBA52 MI:0362 inference MI:0461 interaction database UBA6 UBE2B MI:0362 inference MI:0461 interaction database UBA6 UBE2L3 MI:0045 experimental interaction detection MI:0461 interaction database UBA6 YWHAH MI:0362 inference MI:0461 interaction database UBA6 FMR1 MI:0045 experimental interaction detection MI:0461 interaction database UBA6 ELAVL1 MI:0045 experimental interaction detection MI:0461 interaction database UBA6 UBE2S MI:0045 experimental interaction detection MI:0461 interaction database UBA6 HMBOX1 MI:0045 experimental interaction detection MI:0461 interaction database UBA6 ITCH MI:0045 experimental interaction detection MI:0461 interaction database UBA6 FYTTD1 MI:0045 experimental interaction detection MI:0461 interaction database UBA6 CCDC8 MI:0045 experimental interaction detection MI:0461 interaction database UBA6 UBE2Z MI:0045 experimental interaction detection MI:0461 interaction database UBA6 UBE2T MI:0045 experimental interaction detection MI:0461 interaction database UBA6 AIPL1 MI:0045 experimental interaction detection MI:0461 interaction database UBA6 MBD5 MI:0045 experimental interaction detection MI:0461 interaction database