PTM - CPLM Gene Name UniProt ID Type Position Code UBA6; MOP4; UBE1L2 A0AVT1 Acetylation 544 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 628 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 739 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 544 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 644 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 652 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 687 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 729 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 800 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 830 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 882 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 889 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 295 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 503 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 521 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 709 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 746 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 796 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 871 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 1003 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 182 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 342 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 490 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 169 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 58 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 61 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 810 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 714 K UBA6; MOP4; UBE1L2 A0AVT1 Ubiquitination 672 K

PTM - dbPAF Gene Name UniProt ID Position Type Species UBA6; MOP4; UBE1L2 A0AVT1 1016 T Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 1017 T Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 146 T Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 149 S Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 16 S Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 241 T Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 246 T Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 301 S Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 34 T Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 36 S Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 44 Y Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 54 T Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 637 T Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 650 S Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 654 S Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 665 S Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 737 S Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 743 S Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 817 S Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 818 S Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 951 S Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 979 Y Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 984 T Homo sapiens(Human) UBA6; MOP4; UBE1L2 A0AVT1 994 Y Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA A0AVT1 K544-ac Acetylation KIDAHLNkVCPTTET A0AVT1 K1003-ac Acetylation PVMPGHAkRLKLTMH A0AVT1 S16-p Phosphorylation AHQGEEAsCSSWGTG A0AVT1 S36-p Phosphorylation LPIMSTAsVEIDDAL A0AVT1 Y44-p Phosphorylation VEIDDALySRQRYVL A0AVT1 T54-p Phosphorylation QRYVLGDtAMQKMAK A0AVT1 T146-p Phosphorylation SVPFNETtDLsFLDK A0AVT1 S149-p Phosphorylation FNETtDLsFLDKYQC A0AVT1 T241-p Phosphorylation NHPHkLEtGQFLtFR A0AVT1 T246-p Phosphorylation LEtGQFLtFREINGM A0AVT1 S301-p Phosphorylation PkTVFFEsLERQLKH A0AVT1 T637-p Phosphorylation FPAAIEHtIQWARDk A0AVT1 S737-p Phosphorylation DGSLFWQsPkRPPsP A0AVT1 S743-p Phosphorylation QsPkRPPsPIkFDLN A0AVT1 S951-p Phosphorylation TKIRNGIsFTIWDRW A0AVT1 Y979-p Phosphorylation INAVKEKyGIEPTMV A0AVT1 Y994-p Phosphorylation VQGVKMLyVPVMPGH A0AVT1 T1051-p Phosphorylation RYYFSHDtD______ A0AVT1 K238-ub Ubiquitination CLENHPHkLEtGQFL A0AVT1 K295-ub Ubiquitination AVQVKTPkTVFFEsL A0AVT1 K503-ub Ubiquitination TDPDLIEkSNLNRQF A0AVT1 K521-ub Ubiquitination PHHIQKPkSYTAADA A0AVT1 K544-ub Ubiquitination KIDAHLNkVCPTTET A0AVT1 K628-ub Ubiquitination EIPFCTLkSFPAAIE A0AVT1 K644-ub Ubiquitination tIQWARDkFESSFSH A0AVT1 K652-ub Ubiquitination FESSFSHkPSLFNKF A0AVT1 K687-ub Ubiquitination EGCFQVIkLLSRRPR A0AVT1 K709-ub Ubiquitination LARLKFEkYFNHKAL A0AVT1 K729-ub Ubiquitination FPLDIRLkDGSLFWQ A0AVT1 K739-ub Ubiquitination SLFWQsPkRPPsPIk A0AVT1 K746-ub Ubiquitination kRPPsPIkFDLNEPL A0AVT1 K800-ub Ubiquitination QEFKPSNkVVQTDET A0AVT1 K830-ub Ubiquitination NAIFQLEkAILSNEA A0AVT1 K871-ub Ubiquitination AASNLRAkMYSIEPA A0AVT1 K882-ub Ubiquitination IEPADRFkTKRIAGk A0AVT1 K889-ub Ubiquitination kTKRIAGkIIPAIAT A0AVT1 K1003-ub Ubiquitination PVMPGHAkRLKLTMH

PTM - dbPTM UniProt ID Position Code Type Resources References A0AVT1 1 M Acetylation Swiss-Prot 1010711 19413330 A0AVT1 544 K Acetylation Swiss-Prot 1010711 19608861 A0AVT1 295 K Ubiquitylation Phosphositeplus.1010730 21906983 A0AVT1 503 K Ubiquitylation Phosphositeplus.1010730 21906983 A0AVT1 544 K Ubiquitylation Phosphositeplus.1010730 21890473 A0AVT1 628 K Ubiquitylation Phosphositeplus.1010730 20639865 A0AVT1 644 K Ubiquitylation Phosphositeplus.1010730 21890473 A0AVT1 652 K Ubiquitylation Phosphositeplus.1010730 21890473 A0AVT1 687 K Ubiquitylation Phosphositeplus.1010730 21890473 A0AVT1 729 K Ubiquitylation Phosphositeplus.1010730 21890473 A0AVT1 739 K Ubiquitylation Phosphositeplus.1010730 20639865;21890473;21906983 A0AVT1 830 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 A0AVT1 889 K Ubiquitylation Phosphositeplus.1010730 21890473 A0AVT1 544 K Acetylation Phosphositeplus.1010730 19608861 A0AVT1 637 T Phosphorylation Phosphositeplus.1010730 20068231 A0AVT1 544 K Acetylation HPRD 9.0 19608861 A0AVT1 817 S Phosphorylation HPRD 9.0 20068231 A0AVT1 637 T Phosphorylation HPRD 9.0 20068231 A0AVT1 1016 T Phosphorylation HPRD 9.0 20068231

PTM - HPRD Symbol Position Code Type References UBA6 1016 T Phosphorylation 20068231 UBA6 544 K Acetylation 19608861 UBA6 637 T Phosphorylation 20068231 UBA6 817 S Phosphorylation 20068231

PTM - UniProt UniProt ID Position Type PMIDs A0AVT1 1 N-acetylmethionine 19413330 A0AVT1 54 Phosphothreonine 23186163 A0AVT1 301 Phosphoserine 23186163 A0AVT1 544 N6-acetyllysine 19608861 A0AVT1 737 Phosphoserine 23186163

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 55236 120529 - K Ubiquitination 20639865 55236 120529 - K Ubiquitination 21139048 55236 120529 - K Ubiquitination 21890473 55236 120529 - K Ubiquitination 21906983 55236 120529 - K Ubiquitination 22505724 55236 120529 - K FAT10ylation 22797925 55236 120529 - K Ubiquitination 21963094 55236 120529 - K Ubiquitination 23000965 55236 120529 - K Ubiquitination 24654937 55236 120529 - K Ubiquitination 24816145

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID UBA6 Homo sapiens (Human) 295 "295,VQVKTPKTVFFES" 295:21906983 UBA6 Homo sapiens (Human) 687; 652; 729; 882; 800; 544; 295; 739; 889; 644; 503; 830 "687,GCFQVIKLLSRRP; 652,ESSFSHKPSLFNK; 729,PLDIRLKDGSLFW; 882,EPADRFKTKRIAG; 800,EFKPSNKVVQTDE; 544,IDAHLNKVCPTTE; 295,VQVKTPKTVFFES; 739,LFWQSPKRPPSPI; 889,TKRIAGKIIPAIA; 644,IQWARDKFESSFS; 503,DPDLIEKSNLNRQ; 830,AIFQLEKAILSNE" "687:21890473; 652:21890473; 729:21890473; 882:21890473; 800:21890473; 544:21890473; 295:21906983; 739:21890473,21906983; 889:21890473; 644:21890473; 503:21906983; 830:21890473,21906983" UBA6 Homo sapiens (Human) 326; 356; 170; 255; 70; 408; 415; 178; 213; 265; 29 "326,EFKPSNKVVQTDE; 356,AIFQLEKAILSNE; 170,IQWARDKFESSFS; 255,PLDIRLKDGSLFW; 70,IDAHLNKVCPTTE; 408,EPADRFKTKRIAG; 415,TKRIAGKIIPAIA; 178,ESSFSHKPSLFNK; 213,GCFQVIKLLSRRP; 265,LFWQSPKRPPSPI; 29,DPDLIEKSNLNRQ" "326:21890473; 356:21890473,21906983; 170:21890473; 255:21890473; 70:21890473; 408:21890473; 415:21890473; 178:21890473; 213:21890473; 265:21890473,21906983; 29:21906983" UBA6 Homo sapiens (Human) 295 "295,VQVKTPKTVFFES" 295:21906983 UBA6 Homo sapiens (Human) 687; 652; 729; 882; 800; 544; 739; 889; 644; 830 "687,GCFQVIKLLSRRP; 652,ESSFSHKPSLFNK; 729,PLDIRLKDGSLFW; 882,EPADRFKTKRIAG; 800,EFKPSNKVVQTDE; 544,IDAHLNKVCPTTE; 739,LFWQSPKRPPSPI; 889,TKRIAGKIIPAIA; 644,IQWARDKFESSFS; 830,AIFQLEKAILSNE" 687:21890473; 652:21890473; 729:21890473; 882:21890473; 800:21890473; 544:21890473; 739:21890473; 889:21890473; 644:21890473; 830:21890473