PTM - CPLM Gene Name UniProt ID Type Position Code USP28; KIAA1515 Q96RU2 Ubiquitination 243 K USP28; KIAA1515 Q96RU2 Ubiquitination 381 K USP28; KIAA1515 Q96RU2 Ubiquitination 64 K USP28; KIAA1515 Q96RU2 Ubiquitination 839 K

PTM - dbPAF Gene Name UniProt ID Position Type Species USP28; KIAA1515 Q96RU2 1048 T Homo sapiens(Human) USP28; KIAA1515 Q96RU2 1053 S Homo sapiens(Human) USP28; KIAA1515 Q96RU2 1059 S Homo sapiens(Human) USP28; KIAA1515 Q96RU2 130 T Homo sapiens(Human) USP28; KIAA1515 Q96RU2 131 S Homo sapiens(Human) USP28; KIAA1515 Q96RU2 134 T Homo sapiens(Human) USP28; KIAA1515 Q96RU2 279 S Homo sapiens(Human) USP28; KIAA1515 Q96RU2 375 S Homo sapiens(Human) USP28; KIAA1515 Q96RU2 447 Y Homo sapiens(Human) USP28; KIAA1515 Q96RU2 488 S Homo sapiens(Human) USP28; KIAA1515 Q96RU2 489 T Homo sapiens(Human) USP28; KIAA1515 Q96RU2 491 T Homo sapiens(Human) USP28; KIAA1515 Q96RU2 493 S Homo sapiens(Human) USP28; KIAA1515 Q96RU2 494 S Homo sapiens(Human) USP28; KIAA1515 Q96RU2 495 S Homo sapiens(Human) USP28; KIAA1515 Q96RU2 503 S Homo sapiens(Human) USP28; KIAA1515 Q96RU2 504 S Homo sapiens(Human) USP28; KIAA1515 Q96RU2 517 S Homo sapiens(Human) USP28; KIAA1515 Q96RU2 518 S Homo sapiens(Human) USP28; KIAA1515 Q96RU2 520 S Homo sapiens(Human) USP28; KIAA1515 Q96RU2 521 S Homo sapiens(Human) USP28; KIAA1515 Q96RU2 543 T Homo sapiens(Human) USP28; KIAA1515 Q96RU2 550 S Homo sapiens(Human) USP28; KIAA1515 Q96RU2 654 Y Homo sapiens(Human) USP28; KIAA1515 Q96RU2 67 S Homo sapiens(Human) USP28; KIAA1515 Q96RU2 70 T Homo sapiens(Human) USP28; KIAA1515 Q96RU2 712 S Homo sapiens(Human) USP28; KIAA1515 Q96RU2 713 S Homo sapiens(Human) USP28; KIAA1515 Q96RU2 714 S Homo sapiens(Human) USP28; KIAA1515 Q96RU2 720 S Homo sapiens(Human) USP28; KIAA1515 Q96RU2 753 T Homo sapiens(Human) USP28; KIAA1515 Q96RU2 901 Y Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q96RU2 S67-p Phosphorylation DERVkEPsQDtVATE Q96RU2 T70-p Phosphorylation VkEPsQDtVATEPSE Q96RU2 S113-p Phosphorylation IALSLLEsPKIQADG Q96RU2 T130-p Phosphorylation LNRMHEAtsAEtKRS Q96RU2 S131-p Phosphorylation NRMHEAtsAEtKRSK Q96RU2 T134-p Phosphorylation HEAtsAEtKRSKRKR Q96RU2 S279-p Phosphorylation QLAVNVNsPRNKSEN Q96RU2 S375-p Phosphorylation SRFEFNQsLGQPEkI Q96RU2 Y447-p Phosphorylation PLPDMLKyVIEFAST Q96RU2 S493-p Phosphorylation KESTSTEsSsQDVES Q96RU2 S495-p Phosphorylation STSTEsSsQDVESTF Q96RU2 S503-p Phosphorylation QDVESTFssPEDSLP Q96RU2 S504-p Phosphorylation DVESTFssPEDSLPK Q96RU2 S520-p Phosphorylation KPLTSSRssMEMPSQ Q96RU2 S521-p Phosphorylation PLTSSRssMEMPSQP Q96RU2 T543-p Phosphorylation EEINFVKtCLQRWRs Q96RU2 S550-p Phosphorylation tCLQRWRsEIEQDIQ Q96RU2 Y654-p Phosphorylation YINDKLPyFNAEAAP Q96RU2 S714-p Phosphorylation ESSTNSSsQDYSTsQ Q96RU2 S720-p Phosphorylation SsQDYSTsQEPSVAS Q96RU2 T753-p Phosphorylation TAQAIANtARAYEKS Q96RU2 Y901-p Phosphorylation LFRkVSVyLLTGLEL Q96RU2 T1048-p Phosphorylation IVLKEPPtIRPNsPY Q96RU2 S1053-p Phosphorylation PPtIRPNsPYDLCsR Q96RU2 S1059-p Phosphorylation NsPYDLCsRFAAVME Q96RU2 K99-sm Sumoylation IDLTHDNkDDLQAAI Q96RU2 K45-ub Ubiquitination SFLHEALkASNGDIT Q96RU2 K64-ub Ubiquitination LLTDERVkEPsQDtV Q96RU2 K243-ub Ubiquitination SAALDLLkGAFRSSE Q96RU2 K381-ub Ubiquitination QsLGQPEkIHNKLEF Q96RU2 K839-ub Ubiquitination FFQNEAPkRVVERTL Q96RU2 K897-ub Ubiquitination EDYSLFRkVSVyLLT

PTM - dbPTM UniProt ID Position Code Type Resources References Q96RU2 67 S Phosphorylation Swiss-Prot 1010711 16901786;17525332 Q96RU2 714 S Phosphorylation Swiss-Prot 1010711 16901786;17525332 Q96RU2 67 S Phosphorylation PhosphoELM.10011 17525332 Q96RU2 714 S Phosphorylation PhosphoELM.10011 17525332 Q96RU2 243 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q96RU2 64 K Ubiquitylation Phosphositeplus.1010730 21906983 Q96RU2 839 K Ubiquitylation Phosphositeplus.1010730 21906983 Q96RU2 495 S Phosphorylation Phosphositeplus.1010730 17478428 Q96RU2 67 S Phosphorylation Phosphositeplus.1010730 16901786;17525332 Q96RU2 714 S Phosphorylation Phosphositeplus.1010730 16901786;17478428;17525332 Q96RU2 720 S Phosphorylation Phosphositeplus.1010730 17478428 Q96RU2 67 S Phosphorylation HPRD 9.0 17525332 Q96RU2 131 S Phosphorylation HPRD 9.0 20068231 Q96RU2 714 S Phosphorylation HPRD 9.0 17525332

PTM - HPRD Symbol Position Code Type References USP28 131 S Phosphorylation 20068231 USP28 67 S Phosphorylation 17525332 USP28 714 S Phosphorylation 17525332

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q96RU2 67 S 17525332 HTP Phosphorylation Q96RU2 714 S 17525332 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q96RU2 67 Phosphoserine 16901786 Q96RU2 375 Phosphoserine 23186163 Q96RU2 714 Phosphoserine 16901786 Q96RU2 1048 Phosphothreonine 24275569

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 57646 121683 - K Ubiquitination 22118674 57646 121683 - K Ubiquitination 21139048 57646 121683 - K Ubiquitination 21890473 57646 121683 - K Ubiquitination 21906983 57646 121683 - K Sumoylation 19471022 57646 121683 - K Sumoylation 21252943 57646 121683 - K Ubiquitination 21963094 57646 121683 - K Ubiquitination 23000965 57646 121683 - K Ubiquitination 19850743

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID USP28 Homo sapiens (Human) 243 "243,AALDLLKGAFRSS" 243:21890473 USP28 Homo sapiens (Human) 243 "243,AALDLLKGAFRSS" 243:21890473 USP28 Homo sapiens (Human) 243 "243,AALDLLKGAFRSS" 243:21890473 USP28 Homo sapiens (Human) 243 "243,AALDLLKGAFRSS" 243:21890473 USP28 Homo sapiens (Human) 64; 839; 243 "64,LTDERVKEPSQDT; 839,FQNEAPKRVVERT; 243,AALDLLKGAFRSS" "64:21906983; 839:21906983; 243:21890473,21906983" USP28 Homo sapiens (Human) 807; 64; 243 "807,FQNEAPKRVVERT; 64,LTDERVKEPSQDT; 243,AALDLLKGAFRSS" "807:21906983; 64:21906983; 243:21890473,21906983"