PTM - CPLM Gene Name UniProt ID Type Position Code WDR3 Q9UNX4 Acetylation 65 K WDR3 Q9UNX4 Acetylation 653 K WDR3 Q9UNX4 Ubiquitination 57 K WDR3 Q9UNX4 Ubiquitination 521 K WDR3 Q9UNX4 Ubiquitination 536 K WDR3 Q9UNX4 Ubiquitination 906 K WDR3 Q9UNX4 Ubiquitination 749 K WDR3 Q9UNX4 Ubiquitination 518 K WDR3 Q9UNX4 Ubiquitination 366 K WDR3 Q9UNX4 Ubiquitination 656 K WDR3 Q9UNX4 Ubiquitination 289 K WDR3 Q9UNX4 Ubiquitination 474 K WDR3 Q9UNX4 Ubiquitination 238 K WDR3 Q9UNX4 Ubiquitination 729 K WDR3 Q9UNX4 Ubiquitination 748 K WDR3 Q9UNX4 Ubiquitination 755 K WDR3 Q9UNX4 Ubiquitination 65 K

PTM - dbPAF Gene Name UniProt ID Position Type Species WDR3 Q9UNX4 10 Y Homo sapiens(Human) WDR3 Q9UNX4 102 T Homo sapiens(Human) WDR3 Q9UNX4 13 S Homo sapiens(Human) WDR3 Q9UNX4 211 S Homo sapiens(Human) WDR3 Q9UNX4 240 S Homo sapiens(Human) WDR3 Q9UNX4 241 S Homo sapiens(Human) WDR3 Q9UNX4 247 T Homo sapiens(Human) WDR3 Q9UNX4 257 T Homo sapiens(Human) WDR3 Q9UNX4 333 S Homo sapiens(Human) WDR3 Q9UNX4 373 S Homo sapiens(Human) WDR3 Q9UNX4 456 Y Homo sapiens(Human) WDR3 Q9UNX4 473 T Homo sapiens(Human) WDR3 Q9UNX4 475 T Homo sapiens(Human) WDR3 Q9UNX4 481 Y Homo sapiens(Human) WDR3 Q9UNX4 572 T Homo sapiens(Human) WDR3 Q9UNX4 577 Y Homo sapiens(Human) WDR3 Q9UNX4 580 T Homo sapiens(Human) WDR3 Q9UNX4 586 S Homo sapiens(Human) WDR3 Q9UNX4 588 Y Homo sapiens(Human) WDR3 Q9UNX4 645 S Homo sapiens(Human) WDR3 Q9UNX4 723 Y Homo sapiens(Human) WDR3 Q9UNX4 726 S Homo sapiens(Human) WDR3 Q9UNX4 743 S Homo sapiens(Human) WDR3 Q9UNX4 922 T Homo sapiens(Human) WDR3 Q9UNX4 923 S Homo sapiens(Human) WDR3 Q9UNX4 941 T Homo sapiens(Human) WDR3 Q9UNX4 943 T Homo sapiens(Human) WDR3 Q9UNX4 96 S Homo sapiens(Human)

PTM - PhosSNP Gene Name dbSNP ID Gene Mutation AA Mutation Mutation Position Code Peptide Score Modification Type WDR3 rs3738420 CCC->GCC P->A 240 S DPKKIKGSSPGIQDT 240 Phosphorylation TypeIII-

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q9UNX4 K235-ac Acetylation DPEEPDPkKIkGssP Q9UNX4 K653-ac Acetylation HLFFTAGkDHKIKQW Q9UNX4 R854-m1 Methylation SDVELICrCLFFLLR Q9UNX4 Y10-p Phosphorylation LTKQYLRyVAsAVFG Q9UNX4 S13-p Phosphorylation QYLRyVAsAVFGVIG Q9UNX4 T102-p Phosphorylation LSGEGNVtFNGHKAA Q9UNX4 S211-p Phosphorylation KRLITGAsDSELRVW Q9UNX4 S240-p Phosphorylation DPkKIkGssPGIQDt Q9UNX4 S241-p Phosphorylation PkKIkGssPGIQDtL Q9UNX4 T247-p Phosphorylation ssPGIQDtLEAEDGA Q9UNX4 T257-p Phosphorylation AEDGAFEtDEAPEDR Q9UNX4 S373-p Phosphorylation KSFDLIHsPHGELKA Q9UNX4 Y456-p Phosphorylation IRTMTCEyALCSFFV Q9UNX4 T572-p Phosphorylation AVSLLDCtVKIFYVD Q9UNX4 T580-p Phosphorylation VKIFYVDtLKFFLsL Q9UNX4 S586-p Phosphorylation DtLKFFLsLyGHKLP Q9UNX4 Y588-p Phosphorylation LKFFLsLyGHKLPVI Q9UNX4 S645-p Phosphorylation YLQFVPKsHLFFTAG Q9UNX4 Y723-p Phosphorylation EMEREAEyEEsVAKE Q9UNX4 S726-p Phosphorylation REAEyEEsVAKEDQP Q9UNX4 T941-p Phosphorylation KREKLILtLt_____ Q9UNX4 T943-p Phosphorylation EKLILtLt_______ Q9UNX4 K529-sm Sumoylation FWDFELVkDENSTQK Q9UNX4 K57-ub Ubiquitination WDLRKGEkILILQGL Q9UNX4 K238-ub Ubiquitination EPDPkKIkGssPGIQ Q9UNX4 K289-ub Ubiquitination VVNLAVDkTGRILAC Q9UNX4 K474-ub Ubiquitination RQVVIGTkTGKLQLY Q9UNX4 K521-ub Ubiquitination GGADKSVkFWDFELV

PTM - dbPTM UniProt ID Position Code Type Resources References Q9UNX4 240 S Phosphorylation Swiss-Prot 1010711 16565220;18669648 Q9UNX4 241 S Phosphorylation Swiss-Prot 1010711 18669648 Q9UNX4 247 T Phosphorylation Swiss-Prot 1010711 19413330 Q9UNX4 723 Y Phosphorylation Swiss-Prot 1010711 17053785 Q9UNX4 240 S Phosphorylation PhosphoELM.10011 18669648;16565220 Q9UNX4 241 S Phosphorylation PhosphoELM.10011 18669648 Q9UNX4 333 S Phosphorylation PhosphoELM.10011 18669648 Q9UNX4 247 T Phosphorylation PhosphoELM.10011 18669648 Q9UNX4 238 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9UNX4 521 K Ubiquitylation Phosphositeplus.1010730 21890473 Q9UNX4 57 K Ubiquitylation Phosphositeplus.1010730 21890473 Q9UNX4 240 S Phosphorylation Phosphositeplus.1010730 16565220;18669648;19664995 Q9UNX4 241 S Phosphorylation Phosphositeplus.1010730 18669648;19415658;19664995;19690332;20068231;20815410;21659604 Q9UNX4 102 T Phosphorylation Phosphositeplus.1010730 20068231 Q9UNX4 247 T Phosphorylation Phosphositeplus.1010730 19664995;20815410 Q9UNX4 723 Y Phosphorylation Phosphositeplus.1010730 17053785 Q9UNX4 13 S Phosphorylation HPRD 9.0 20068231 Q9UNX4 96 S Phosphorylation HPRD 9.0 20068231 Q9UNX4 240 S Phosphorylation HPRD 9.0 16565220,18669648,19664995,18452278,20068231 Q9UNX4 241 S Phosphorylation HPRD 9.0 18669648,19415658,19664995,19651622,18452278,20068231 Q9UNX4 333 S Phosphorylation HPRD 9.0 18669648 Q9UNX4 743 S Phosphorylation HPRD 9.0 20068231 Q9UNX4 102 T Phosphorylation HPRD 9.0 20068231 Q9UNX4 247 T Phosphorylation HPRD 9.0 17081983,18669648,19413330,19664995,18452278 Q9UNX4 941 T Phosphorylation HPRD 9.0 20068231 Q9UNX4 10 Y Phosphorylation HPRD 9.0 20068231 Q9UNX4 240 S Phosphorylation SysPTM 1.1 16565220

PTM - HPRD Symbol Position Code Type References WDR3 10 Y Phosphorylation 20068231 WDR3 102 T Phosphorylation 20068231 WDR3 13 S Phosphorylation 20068231 WDR3 240 S Phosphorylation 16565220,18669648,19664995,18452278,20068231 WDR3 241 S Phosphorylation 18669648,19415658,19664995,19651622,18452278,20068231 WDR3 247 T Phosphorylation 17081983,18669648,19413330,19664995,18452278 WDR3 333 S Phosphorylation 18669648 WDR3 743 S Phosphorylation 20068231 WDR3 941 T Phosphorylation 20068231 WDR3 96 S Phosphorylation 20068231

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q9UNX4 240 S 18669648 HTP Phosphorylation Q9UNX4 240 S 16565220 HTP Phosphorylation Q9UNX4 247 T 18669648 HTP Phosphorylation Q9UNX4 333 S 18669648 HTP Phosphorylation Q9UNX4 241 S 18669648 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q9UNX4 240 Phosphoserine 18669648 Q9UNX4 241 Phosphoserine 18669648 Q9UNX4 257 Phosphothreonine 23186163 Q9UNX4 726 Phosphoserine 23186163

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type WDR3 IPI00009471 S 241 KKIKGSpSPGIQDT phosphorylation WDR3 IPI00009471 T 580 KIFYVDpTLKFFLS phosphorylation WDR3 IPI00009471 Y 577 CTVKIFpYVDTLKF phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 10885 116092 - K Ubiquitination 22178446 10885 116092 - K Sumoylation 21693764 10885 116092 - K Ubiquitination 21963094 10885 116092 - K Ubiquitination 21139048 10885 116092 - K Ubiquitination 21890473 10885 116092 - K Ubiquitination 21906983 10885 116092 - K Sumoylation 19471022 10885 116092 - K Sumoylation 21252943 10885 116092 - K Ubiquitination 22505724 10885 116092 - K Ubiquitination 24816145

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID WDR3 Homo sapiens (Human) 57; 521 "57,DLRKGEKILILQG; 521,GADKSVKFWDFEL" 57:21890473; 521:21890473 WDR3 Homo sapiens (Human) 57; 521 "57,DLRKGEKILILQG; 521,GADKSVKFWDFEL" 57:21890473; 521:21890473 WDR3 Homo sapiens (Human) 57; 521 "57,DLRKGEKILILQG; 521,GADKSVKFWDFEL" 57:21890473; 521:21890473 WDR3 Homo sapiens (Human) 238; 57; 521 "238,PDPKKIKGSSPGI; 57,DLRKGEKILILQG; 521,GADKSVKFWDFEL" 238:21906983; 57:21890473; 521:21890473