PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus KDM5A GATAD1 20850016,26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G KDM5A EZH2 18483221 biogrid exp GP P G GP GP P GP G GP G P P P GP GP GP GP KDM5A MORF4L2 17573780 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TBP KDM5A 7935440 hprd,biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP GP GP GP GP G NR3C1 KDM5A 11358960 hprd,biogrid,i2d,bci exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SIN3B KDM5A 17573780,26496610 biogrid,intact exp GP GP G G G GP G GP GP G GP G GP G G G GP G GP G GP GP G G G G GP GP G KDM5A RBBP7 26186194 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A TM9SF4 26496610 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP GP GP GP G EED KDM5A 18483221 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G KDM5A HIST3H3 20850016 biogrid exp P P P P P P P P P P P P P P P P P P P P P P VDR KDM5A 11358960 hprd,biogrid,i2d,bci exp G G G G G G G G G G G G G G G G G G G G KDM5A MXD1 19762557 biogrid exp GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G RARA KDM5A 11358960 hprd,biogrid,i2d,bci exp G G G G G G G G G G G G G G G G G G G G G G G G G G KDM5A FOXK2 25609649 intact exp GP GP G G GP GP G GP GP G GP GP G G G GP GP G GP G GP GP G GP GP G GP GP G KDM5A CCT6A 23414517 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A PHF12 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A RBPJ 20231316 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KDM5A HIST2H3A, HIST2H3C, HIST2H3D 17320161 biogrid exp, ortho P P P P P P P P P P P P P P P P P P P P P P KDM5A HDAC1 26496610,23752268, 25402006 biogrid,intact exp, ortho, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G KDM5A SUZ12 18483221, 25402006 biogrid exp, ortho, pred G G G G GP G G G GP G GP G G GP G GP G G G G GP G G G GP G GP G G RBL1 KDM5A 7935440, 25402006 hprd,biogrid,bci exp, pred P P G GP P P GP P P P GP P P P P P P GP GP GP GP P ESR1 KDM5A 11358960, 21836163 hprd,biogrid,bci exp, pred GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G RB1 KDM5A 11358960,7935440,22615382,15949438, 25402006, 21836163 hprd,biogrid,i2d,dip,bci exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A HDAC2 17573780, 25402006 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A MORF4L1 17573780,26186194, 25402006 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G LMO2 KDM5A 9129143, 21836163 hprd,biogrid,bci exp, pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G KDM5A KDM5A 17884155, 23023127 intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A FUBP3 ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A ASH2L ortho GP GP G G GP GP G GP GP G GP G G G G GP GP GP GP G GP GP G G GP G GP GP G KDM5A EXOC2 ortho G G G G G GP G G GP G GP GP G G G GP GP G GP G GP G G G GP G GP GP G KDM5A SIN3A ortho GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A MCM7 ortho GP GP G G GP G G G GP G G G G GP G GP G GP G G GP GP GP G GP G GP GP G KDM5A PPP2R2D ortho GP GP G P GP P GP P G GP GP GP GP G P P P P GP GP GP P KDM5A MCM6 ortho GP GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G KDM5A CHD5 ortho P P G P GP P P G P P P P P GP P P G P P P P P P P GP KDM5A MCM4 ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A NAP1L1 ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A SLC35G1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KDM5A CTBP2 ortho GP G G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP G GP GP G KDM5A NF2 ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A ASF1A ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KDM5A SNAPC3 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KDM5A THOC1 25402006 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP G GP GP G GP GP G KDM5A PRMT2 25402006 pred G GP G G GP GP G GP GP G GP G G GP G GP GP GP GP G GP GP GP GP GP G GP GP G HDAC3 KDM5A 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A KDM7A 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A CHD6 23023127 pred G G G G G GP G GP GP G G G GP G G G GP G G G G G G GP G G G G G E2F3 KDM5A 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G KDM5A FOXP3 23023127 pred G G G P P G G G P P KDM5A CUX1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CBX4 KDM5A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G KDM5A AATF 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KDM5A BBX 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM4A KDM5A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP G G GP GP G GP GP GP GP GP G KDM5A LDB1 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G KDM5A SMARCC1 23023127 pred GP G G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP G G GP GP GP GP G KDM5A PRDM2 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G TAL1 KDM5A 25402006 pred G G G G GP GP G G G G G G G G G G GP G G G G G G G G G G G KDM5A KAT2B 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G KDM5A TRIP11 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G KDM5A NUP98 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G KDM5A RLIM 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A NEDD4 23023127 pred GP GP G GP P G GP GP GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP P G SERPINB2 KDM5A 25402006 pred G P G G P P P P P P P GP G P P P KDM5A NCOA6 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM4B KDM5A 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KDM5A CBX5 25402006 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G KDM5A ARID2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SP1 KDM5A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A BPTF 25402006, 23023127 pred G GP G G G GP G G GP G GP GP GP G G GP GP GP G G GP G GP G GP G GP GP G KDM5A CDYL 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G GATA1 KDM5A 25402006 pred G GP KDM5A MRPS18B 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ARID4A KDM5A 25402006 pred G P G GP G P G P GP G G P GP G P G P G G GP GP G G P G KDM5A BRF1 25402006 pred G G G G G G G G G G G G G KDM5A PURA 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G AR KDM5A 25402006 pred GP G G G G G G G G G G G G G G G G G G G G G G G GP G KDM5A PA2G4 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A USP4 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP G GP GP G KDM5A CCND2 25402006 pred GP GP G G G GP G GP GP G GP GP G G G GP GP G GP G G G G GP GP G GP G G KDM5A E2F2 25402006 pred GP GP G G G GP G G G P P G G G GP GP G P P G G G GP GP BRD1 KDM5A 23023127 pred G G G G G GP G G G G G G G G G G GP G G G G G G G G G G GP G HBP1 KDM5A 25402006 pred G GP G G G GP G GP GP G GP G G G G G GP G G G GP GP G GP G G GP GP G UBTF KDM5A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A SMARCA4 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A KMT2E 23023127 pred G G G G GP G G G G G G G G G G G G G G G G G G G G G G GP G KDM5A SNAPC1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G KDM5A E4F1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CCNT2 KDM5A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A EP300 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A RBBP4 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A FRK 25402006 pred P P P P P P P P P P P P P P P P P P P KDM5A KDM4D 23023127 pred P P P P P P P P P P GP KDM5A JADE2 23023127 pred G GP G G G GP G G GP G G G G G G GP GP GP G G GP GP G GP GP G G G G ATF2 KDM5A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G KDM5A BAZ1A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TAF1 KDM5A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A KDM5B 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A TLE4 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KDM5A EID1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RBBP9 KDM5A 25402006 pred G GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G KDM5A E2F4 25402006 pred G GP G G G GP G G GP G GP GP GP G G GP GP G GP G GP GP GP G GP G GP G G TP73 KDM5A 25402006 pred G G G G G SUV39H1 KDM5A 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KDM5A WNK1 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G G G G GP G GP G GP G KDM5A MBD2 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G KDM5A CXXC1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KDM5A DGKZ 25402006 pred G G G G G GP G GP G G G G G GP G G GP G GP G G G GP G G G GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P29375 Q16695 unspecified method 20850016 direct interaction X 2 P29375 P25791 pull down 9129143 direct interaction X 2 P29375 P25791 affinity chromatography technology 9129143 physical association X 2 P29375 pull down 11358960 direct interaction X 2 P29375 P10276 pull down 11358960 direct interaction X 2 P29375 affinity chromatography technology 11358960 physical association X 2 P29375 P20226 pull down 7935440 direct interaction X 2 P29375 P25791 two hybrid 9129143 direct interaction X 2 P29375 Q05195 affinity chromatography technology 19762557 physical association X 2 P29375 affinity chromatography technology 18483221 physical association X 2 P29375 affinity chromatography technology 18483221 physical association X 2 P29375 Q9UBU8-3 affinity chromatography technology 17573780 physical association X 2 P29375 Q9UBU8-3 affinity chromatography technology 17573780 physical association X 2 P29375 Q9UBU8-3 affinity chromatography technology 17573780 physical association X 2 Q15014 P29375 affinity chromatography technology 17573780 physical association X 2 Q15014 P29375 affinity chromatography technology 17573780 physical association X 2 Q15022 P29375 affinity chromatography technology 18483221 physical association X 2 P29375 A0A024RDV3 two hybrid 15949438 direct interaction X 2 P29375 A0A024RDV3 affinity chromatography technology 15949438 physical association X 2 P29375 Q13547 affinity chromatography technology 23752268 physical association X 2 P29375 P55854 affinity chromatography technology 25391492 physical association X 2 P29375 Q8WUU5 affinity chromatography technology 20850016 physical association X 2 P29375 pull down 11358960 direct interaction X 2 P29375 A0A024RDV3 affinity chromatography technology 11358960 physical association X 2 P29375 A0A024RDV3 pull down 7935440 direct interaction X 2 P29375 P28749-2 pull down 7935440 direct interaction X 2 P29375 A0A024RDV3 affinity chromatography technology 7935440 physical association X 2 P29375 E9PJK2 affinity chromatography technology 18483221 physical association X 2 P29375 O75182 affinity chromatography technology 17573780 physical association X 2 P29375 Q92769 affinity chromatography technology 17573780 physical association X 2 P29375 Q06330-7 pull down 20231316 direct interaction X 2 P29375 Q06330-7 affinity chromatography technology 20231316 physical association X 2 P29375 Q06330-7 biochemical 20231316 association X 2 P29375 P61956-2 affinity chromatography technology 21693764 physical association X 2 P11473-2 P29375 pull down 11358960 direct interaction X 2 P0CG48 P29375 affinity chromatography technology 22505724 physical association X 2 P0CG48 P29375 affinity chromatography technology 21963094 physical association X 2 P0CG48 P29375 affinity chromatography technology 21139048 physical association X 2 P0CG48 P29375 affinity chromatography technology 21890473 physical association X 2 Q71DI3 P29375 pull down 17320161 direct interaction X 2 P29375 anti tag coimmunoprecipitation 23752268 association C 91 P29375 P89884 two hybrid array 22028648 physical association X 2 P29375 A0A024RDL1 two hybrid fragment pooling approach 23414517 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B KDM5A HDAC2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17573780,22318606 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0799(additive genetic interaction defined by inequality)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_192769|BIOGRID_138093 prey|bait bait|prey KDM5A MXD1 MI:0004(affinity chromatography technology) 19762557 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_127633 prey bait KDM5A SUMO2 MI:0004(affinity chromatography technology) 21693764 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_165980 prey bait TBP KDM5A MI:0096(pull down)|MI:0492(in vitro) 7935440 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_92804|HPRD_6238 bait|- prey|- KDM5A RBPJ MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down) 20231316 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0914(association) (biogrid)|(biogrid)|(biogrid) BIOGRID_139226|BIOGRID_139225|BIOGRID_139227 bait|prey|prey prey|bait|bait SIN3B KDM5A MI:0004(affinity chromatography technology) 17573780 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_138092 prey bait KDM5A MORF4L1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17573780 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_138088|BIOGRID_138091|BIOGRID_137990 prey|bait|prey bait|prey|bait RARA KDM5A MI:0492(in vitro)|MI:0096(pull down) 11358960 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction) MI:0468(hprd)|(biogrid) HPRD_14413|BIOGRID_92797 -|bait -|prey EED KDM5A MI:0004(affinity chromatography technology) 18483221 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_132386 prey bait ESR1 KDM5A MI:0492(in vitro)|MI:0096(pull down)|MI:0096(pull down) 11358960 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(biogrid) HPRD_14894|BIOGRID_92796|BIOGRID_92801 -|bait|bait -|prey|prey KDM5A KDM5A MI:0870(demethylase assay) 18836456 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0465(dip) DIP_54475 - - RBL1 KDM5A MI:0096(pull down)|MI:0492(in vitro) 7935440 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_92805|HPRD_18697 bait|- prey|- VDR KDM5A MI:0096(pull down)|MI:0492(in vitro) 11358960 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_92799|HPRD_9823 bait|- prey|- NR3C1 KDM5A MI:0096(pull down)|MI:0492(in vitro) 11358960 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_92798|HPRD_34573 bait|- prey|- LMO2 KDM5A MI:0493(in vivo)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 9129143 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid) HPRD_2769|BIOGRID_92794|BIOGRID_77511|BIOGRID_92795 -|prey|bait|bait -|bait|prey|prey KDM5A HIST2H3A; MI:0096(pull down) 17320161 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_118663 bait prey KDM5A HDAC1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 23752268 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association) (biogrid)|(intact) BIOGRID_280521|UniProt_131412 prey|prey bait|bait UBC KDM5A MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21139048,21890473,21963094,22505724 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_264860|BIOGRID_175926|BIOGRID_224758|BIOGRID_172204 bait|bait|bait|bait prey|prey|prey|prey KDM5A CCT6A MI:0663(confocal microscopy) 23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_126896 prey bait RB1 KDM5A MI:0401(biochemical)|MI:0492(in vitro)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid) 11358960,15949438,7935440,8414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0465(dip)|MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) DIP_52291|HPRD_2641|BIOGRID_92802|BIOGRID_92803|BIOGRID_92806|BIOGRID_214170|BIOGRID_214171 -|-|bait|bait|prey|prey|prey -|-|prey|prey|bait|bait|bait KDM5A EZH2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 18483221 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_132385|BIOGRID_132387 bait|prey prey|bait KDM5A SUZ12 MI:0004(affinity chromatography technology) 18483221 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_132389 prey bait KDM5A MORF4L2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17573780 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_138087|BIOGRID_138023 prey|prey bait|bait

PPI - HINT Gene A Gene B PMID Method Quality SIN3B KDM5A 26496610,17573780,26496610 0007,0004,0004 HT,LC RB1 KDM5A 15949438,22615382,7935440,15949438,8414517,7935440,11358960 0018,0006,0096,0004,0401,0004,0004 LC KDM5A FOXK2 25609649,25609649 0676,0004 HT KDM5A HDAC1 26496610,23752268,23752268,26496610 0007,0007,0004,0004 HT,LC KDM5A RBBP7 26186194 0004 HT KDM5A GATAD1 26496610,20850016,26496610 0007,0004,0004 HT,LC KDM5A TM9SF4 26496610,26496610 0007,0004 HT KDM5A PHF12 26496610,26496610 0007,0004 HT KDM5A MORF4L1 26186194,17573780 0004,0004 HT,LC SIN3B KDM5A 26496610,26496610 0007,0004 HT KDM5A FOXK2 25609649,25609649 0676,0004 HT KDM5A HDAC1 26496610,26496610 0007,0004 HT KDM5A RBBP7 26186194 0004 HT KDM5A GATAD1 26496610,26496610 0007,0004 HT KDM5A TM9SF4 26496610,26496610 0007,0004 HT KDM5A PHF12 26496610,26496610 0007,0004 HT KDM5A MORF4L1 26186194 0004 HT SIN3B KDM5A 17573780 0004 LC RB1 KDM5A 15949438,22615382,7935440,15949438,8414517,7935440,11358960 0018,0006,0096,0004,0401,0004,0004 LC KDM5A HDAC1 23752268,23752268 0007,0004 LC KDM5A GATAD1 20850016 0004 LC KDM5A MORF4L1 17573780 0004 LC RB1 KDM5A 15949438,15949438,8414517 0018,0004,0401 LC LMO2 KDM5A 9129143,9129143,9129143 0004,0018,0096 LC KDM5A KDM5A 27499454 0114 LC KDM5A CCT6A 23414517 0399 HT KDM5A RBPJ 20231316,20231316,20231316 0004,0401,0096 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q05195 P29375 MXD1 KDM5A 0.21 19762557 P29375 P10276 KDM5A RARA 0.309 11358960 P29375 P11473 KDM5A VDR 0.309 11358960 P29375 P04150 KDM5A NR3C1 0.309 11358960 Q8VE37 P29375 RCC1 KDM5A 0.236 26496610 Q8WUU5 P29375 GATAD1 KDM5A 0.236 26496610,20850016 P29375 P03372 KDM5A ESR1 0.454 11358960 P29375 P06400 KDM5A RB1 0.772 8414517,7935440,11358960,15949438 Q9CWZ3 P29375 RBM8A KDM5A 0.236 26496610 Q01167 P29375 FOXK2 KDM5A 0.236 25609649 Q13547 P29375 HDAC1 KDM5A 0.332 26496610,23752268 P29375 O75182 KDM5A SIN3B 0.236 26496610,17573780 P29375 O75530 KDM5A EED 0.21 18483221 P29375 P25791 KDM5A LMO2 0.623 9129143 P89884 P29375 V-BCL-2 KDM5A 0.126 22028648 Q06330 P29375 RBPJ KDM5A 0.569 20231316 Q15910 P29375 EZH2 KDM5A 0.376 18483221 Q71DI3 P29375 HIST2H3D KDM5A 0.309 17320161 Q92769 P29375 HDAC2 KDM5A 0.126 17573780 Q9UBU8 P29375 MORF4L1 KDM5A 0.332 17573780,26186194 Q92544 P29375 TM9SF4 KDM5A 0.126 26496610 Q96QT6 P29375 PHF12 KDM5A 0.126 26496610 P29375 P28749 KDM5A RBL1 0.309 7935440 P40227 P29375 CCT6A KDM5A 0.126 23414517 Q15014 P29375 MORF4L2 KDM5A 0.126 17573780 Q15022 P29375 SUZ12 KDM5A 0.21 18483221 P29375 P20226 KDM5A TBP 0.309 7935440 Q16576 P29375 RBBP7 KDM5A 0.126 26186194 Q16695 P29375 HIST3H3 KDM5A 0.183 20850016

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 SIN3B KDM5A MI:0045 experimental interaction detection MI:0461 interaction database EED KDM5A MI:0045 experimental interaction detection MI:0461 interaction database MYC KDM5A MI:0045 experimental interaction detection MI:0461 interaction database ESR1 KDM5A MI:0045 experimental interaction detection MI:0461 interaction database NR3C1 KDM5A MI:0045 experimental interaction detection MI:0461 interaction database RB1 KDM5A MI:0045 experimental interaction detection MI:0461 interaction database UBC KDM5A MI:0045 experimental interaction detection MI:0461 interaction database RARA KDM5A MI:0045 experimental interaction detection MI:0461 interaction database VDR KDM5A MI:0045 experimental interaction detection MI:0461 interaction database RCC1 KDM5A MI:0362 inference MI:0461 interaction database TBP KDM5A MI:0045 experimental interaction detection MI:0461 interaction database TAF1 KDM5A MI:0045 experimental interaction detection MI:0461 interaction database LMO2 KDM5A MI:0045 experimental interaction detection MI:0461 interaction database RBL1 KDM5A MI:0045 experimental interaction detection MI:0461 interaction database KDM5A MCM4 MI:0362 inference MI:0461 interaction database KDM5A MCM7 MI:0362 inference MI:0461 interaction database KDM5A NF2 MI:0362 inference MI:0461 interaction database KDM5A CCT6A MI:0045 experimental interaction detection MI:0461 interaction database KDM5A LHX1 MI:0362 inference MI:0461 interaction database KDM5A NAP1L1 MI:0362 inference MI:0461 interaction database KDM5A SUMO3 MI:0045 experimental interaction detection MI:0461 interaction database KDM5A CTBP2 MI:0362 inference MI:0461 interaction database KDM5A MAX MI:0045 experimental interaction detection MI:0461 interaction database KDM5A SUMO2 MI:0045 experimental interaction detection MI:0461 interaction database KDM5A PPP2R2A MI:0362 inference MI:0461 interaction database KDM5A HIST1H3A MI:0362 inference MI:0461 interaction database KDM5A PPP2R2B MI:0362 inference MI:0461 interaction database KDM5A E2F1 MI:0045 experimental interaction detection MI:0461 interaction database KDM5A FOXK2 MI:0045 experimental interaction detection MI:0461 interaction database KDM5A EWSR1 MI:0362 inference MI:0461 interaction database KDM5A MXD1 MI:0045 experimental interaction detection MI:0461 interaction database KDM5A RBPJ MI:0045 experimental interaction detection MI:0461 interaction database KDM5A CTBP1 MI:0362 inference MI:0461 interaction database KDM5A HDAC1 MI:0045 experimental interaction detection MI:0461 interaction database KDM5A MCM6 MI:0362 inference MI:0461 interaction database KDM5A MORF4L2 MI:0045 experimental interaction detection MI:0461 interaction database KDM5A SUZ12 MI:0045 experimental interaction detection MI:0461 interaction database KDM5A EZH2 MI:0045 experimental interaction detection MI:0461 interaction database KDM5A RBBP7 MI:0045 experimental interaction detection MI:0461 interaction database KDM5A NFE2 MI:0362 inference MI:0461 interaction database KDM5A HIST3H3 MI:0362 inference MI:0461 interaction database KDM5A PPP2R2D MI:0362 inference MI:0461 interaction database KDM5A ARID2 MI:0362 inference MI:0461 interaction database KDM5A H3F3C MI:0362 inference MI:0461 interaction database KDM5A HIST2H3A MI:0045 experimental interaction detection MI:0461 interaction database KDM5A EMSY MI:0362 inference MI:0461 interaction database KDM5A GATAD1 MI:0045 experimental interaction detection MI:0461 interaction database KDM5A TM9SF4 MI:0045 experimental interaction detection MI:0461 interaction database KDM5A HDAC2 MI:0045 experimental interaction detection MI:0461 interaction database KDM5A LHX4 MI:0362 inference MI:0461 interaction database KDM5A ZBTB9 MI:0362 inference MI:0461 interaction database KDM5A FUBP3 MI:0362 inference MI:0461 interaction database KDM5A EXOC2 MI:0362 inference MI:0461 interaction database KDM5A PHF12 MI:0045 experimental interaction detection MI:0461 interaction database KDM5A SIN3A MI:0362 inference MI:0461 interaction database KDM5A LHX5 MI:0362 inference MI:0461 interaction database KDM5A EPB41L5 MI:0362 inference MI:0461 interaction database KDM5A ASF1B MI:0362 inference MI:0461 interaction database KDM5A ASH2L MI:0362 inference MI:0461 interaction database KDM5A LHX3 MI:0362 inference MI:0461 interaction database KDM5A MORF4L1 MI:0045 experimental interaction detection MI:0461 interaction database KDM5A GPN3 MI:0362 inference MI:0461 interaction database KDM5A ASF1A MI:0362 inference MI:0461 interaction database KDM5A PPP2R2C MI:0362 inference MI:0461 interaction database KDM5A RBM8A MI:0362 inference MI:0461 interaction database