PTM - CPLM Gene Name UniProt ID Type Position Code KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 425 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 152 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 713 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 733 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 135 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 238 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 820 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 1151 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 339 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 347 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 789 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 805 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 191 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 1294 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 1209 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 106 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 137 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 159 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 982 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 1302 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 45 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 127 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 113 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 924 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 895 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 247 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 714 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 1275 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 847 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 1087 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 1029 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 1094 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 222 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 774 K KDM5A; JARID1A; RBBP2; RBP2 P29375 Ubiquitination 758 K

PTM - dbPAF Gene Name UniProt ID Position Type Species KDM5A; JARID1A; RBBP2; RBP2 P29375 1075 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1111 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1143 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1280 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1327 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1329 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1330 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1331 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1335 T Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1338 Y Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 134 T Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1343 T Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1345 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1352 T Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1365 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1366 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1368 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1404 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1410 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1414 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1415 T Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1423 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1438 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 148 Y Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1488 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1579 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1580 T Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1595 Y Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1598 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1603 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1666 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1674 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 1679 Y Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 201 T Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 203 T Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 204 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 223 T Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 225 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 399 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 46 T Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 868 T Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 871 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 918 T Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 970 S Homo sapiens(Human) KDM5A; JARID1A; RBBP2; RBP2 P29375 973 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA P29375 K924-ac Acetylation VtLDVMKkLIDSGVG P29375 T46-p Phosphorylation IRPLAEktGICKIRP P29375 T134-p Phosphorylation KGGFEMVtKEKKWSK P29375 S160-p Phosphorylation GTGSLLKsHyERILY P29375 Y162-p Phosphorylation GSLLKsHyERILYPY P29375 T203-p Phosphorylation VLSTDTQtsPEPGTR P29375 S204-p Phosphorylation LSTDTQtsPEPGTRM P29375 S225-p Phosphorylation TRRVkTQsESGDVSR P29375 T285-p Phosphorylation QMRQRKGtLsVNFVD P29375 S287-p Phosphorylation RQRKGtLsVNFVDLY P29375 S399-p Phosphorylation KEFWRLVsSIEEDVI P29375 T918-p Phosphorylation LSDPQQVtLDVMKkL P29375 S970-p Phosphorylation LQARPRHsVAsLESI P29375 S973-p Phosphorylation RPRHsVAsLESIVNE P29375 S1066-p Phosphorylation RTFLKKNsSHtLLQV P29375 T1069-p Phosphorylation LKKNsSHtLLQVLsP P29375 S1075-p Phosphorylation HtLLQVLsPRTDIGV P29375 S1111-p Phosphorylation DLDLEPLsDLEEGLE P29375 S1143-p Phosphorylation KEIEAMHsLRAANLA P29375 T1225-p Phosphorylation SRRPRLEtILSLLVS P29375 S1255-p Phosphorylation CLTERAMsWQDRARQ P29375 S1280-p Phosphorylation LAKLSVLsQRMVEQA P29375 S1327-p Phosphorylation AFNRVVSsVsssPRQ P29375 S1329-p Phosphorylation NRVVSsVsssPRQTM P29375 S1330-p Phosphorylation RVVSsVsssPRQTMD P29375 S1331-p Phosphorylation VVSsVsssPRQTMDY P29375 T1343-p Phosphorylation MDYDDEEtDsDEDIR P29375 S1345-p Phosphorylation YDDEEtDsDEDIRET P29375 S1365-p Phosphorylation KDTASVKsSSSLEPN P29375 S1410-p Phosphorylation SSASKSCsQGSstPR P29375 S1414-p Phosphorylation KSCsQGSstPRKQPR P29375 T1415-p Phosphorylation SCsQGSstPRKQPRK P29375 S1423-p Phosphorylation PRKQPRKsPLVPRSL P29375 S1438-p Phosphorylation EPPVLELsPGAKAQL P29375 S1488-p Phosphorylation LHIMEDDsMEEKPLK P29375 S1579-p Phosphorylation KVELVKEsTEKKREK P29375 S1598-p Phosphorylation IPSKYDWsGAEEsDD P29375 S1603-p Phosphorylation DWsGAEEsDDENAVC P29375 S1666-p Phosphorylation AKKQGPVsPGPAPPP P29375 S1674-p Phosphorylation PGPAPPPsFIMSYKL P29375 K191-sm Sumoylation PNLDLKEkVEPEVLS P29375 K222-sm Sumoylation PKRTRRVkTQsESGD P29375 K895-sm Sumoylation LPELPRLkQELQQAR P29375 K1382-sm Sumoylation CDEEIPIkSEEVVTH P29375 K45-ub Ubiquitination RIRPLAEktGICKIR P29375 K106-ub Ubiquitination ELQGSTLkIPVVERK P29375 K152-ub Ubiquitination RLGYLPGkGTGSLLK P29375 K222-ub Ubiquitination PKRTRRVkTQsESGD P29375 K347-ub Ubiquitination CVAEECSkPREAFGF P29375 K425-ub Ubiquitination FGSGFPVkDGRRKIL

PTM - dbPTM UniProt ID Position Code Type Resources References P29375 1111 S Phosphorylation Swiss-Prot 1010711 17081983;18669648;19690332 P29375 1331 S Phosphorylation Swiss-Prot 1010711 15302935;18669648 P29375 1343 T Phosphorylation Swiss-Prot 1010711 19690332 P29375 1345 S Phosphorylation Swiss-Prot 1010711 19690332 P29375 1598 S Phosphorylation Swiss-Prot 1010711 17081983 P29375 1603 S Phosphorylation Swiss-Prot 1010711 17081983 P29375 1666 S Phosphorylation Swiss-Prot 1010711 15302935 P29375 1111 S Phosphorylation PhosphoELM.10011 18669648;17081983 P29375 1330 S Phosphorylation PhosphoELM.10011 18669648 P29375 1331 S Phosphorylation PhosphoELM.10011 18669648;15302935 P29375 1666 S Phosphorylation PhosphoELM.10011 15302935 P29375 1382 K Sumoylation Phosphositeplus.1010730 15161980 P29375 425 K Ubiquitylation Phosphositeplus.1010730 21890473 P29375 1111 S Phosphorylation Phosphositeplus.1010730 18669648;19276368;19690332;20068231;20363803;20815410;21659604;22115753 P29375 1331 S Phosphorylation Phosphositeplus.1010730 15302935;18669648 P29375 1345 S Phosphorylation Phosphositeplus.1010730 19690332;21406692;22115753 P29375 1423 S Phosphorylation Phosphositeplus.1010730 19691289;20068231 P29375 1666 S Phosphorylation Phosphositeplus.1010730 15302935;21406692 P29375 1343 T Phosphorylation Phosphositeplus.1010730 19690332;21406692;22115753 P29375 46 T Phosphorylation Phosphositeplus.1010730 20068231 P29375 148 Y Phosphorylation Phosphositeplus.1010730 18083107 P29375 1679 Y Phosphorylation Phosphositeplus.1010730 18083107 P29375 1111 S Phosphorylation HPRD 9.0 17081983,18669648,19651622,18452278,20068231 P29375 1329 S Phosphorylation HPRD 9.0 19691289 P29375 1330 S Phosphorylation HPRD 9.0 18669648 P29375 1331 S Phosphorylation HPRD 9.0 15302935,18669648,19691289,20068231 P29375 1331 S Phosphorylation HPRD 9.0 18669648,19691289,20068231 P29375 1345 S Phosphorylation HPRD 9.0 18452278 P29375 1423 S Phosphorylation HPRD 9.0 19691289,20068231 P29375 1488 S Phosphorylation HPRD 9.0 18452278 P29375 1598 S Phosphorylation HPRD 9.0 17081983 P29375 1603 S Phosphorylation HPRD 9.0 17081983 P29375 46 T Phosphorylation HPRD 9.0 20068231 P29375 1343 T Phosphorylation HPRD 9.0 18452278 P29375 1111 S Phosphorylation SysPTM 1.1 17081983;18669648 P29375 1331 S Phosphorylation SysPTM 1.1 15302935;18669648 P29375 1666 S Phosphorylation SysPTM 1.1 15302935

PTM - HPRD Symbol Position Code Type References KDM5A 1111 S Phosphorylation 17081983,18669648,19651622,18452278,20068231 KDM5A 1329 S Phosphorylation 19691289 KDM5A 1330 S Phosphorylation 18669648 KDM5A 1331 S Phosphorylation 15302935,18669648,19691289,20068231 KDM5A 1331 S Phosphorylation 18669648,19691289,20068231 KDM5A 1343 T Phosphorylation 18452278 KDM5A 1345 S Phosphorylation 18452278 KDM5A 1423 S Phosphorylation 19691289,20068231 KDM5A 1428 S Phosphorylation 19691289,20068231 KDM5A 1488 S Phosphorylation 18452278 KDM5A 1493 S Phosphorylation 18452278 KDM5A 1598 S Phosphorylation 17081983 KDM5A 1603 S Phosphorylation 17081983 KDM5A 1608 S Phosphorylation 17081983 KDM5A 46 T Phosphorylation 20068231

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type P29375 1698 S 15302935 HTP Phosphorylation P29375 1331 S 18669648 HTP Phosphorylation P29375 1331 S 15302935 HTP Phosphorylation P29375 1330 S 18669648 HTP Phosphorylation P29375 1111 S 18669648 HTP Phosphorylation P29375 1111 S 17081983 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs P29375 204 Phosphoserine 23186163 P29375 1111 Phosphoserine 18669648;19690332;20068231;24275569 P29375 1330 Phosphoserine 23186163 P29375 1331 Phosphoserine 18669648 P29375 1438 Phosphoserine 23186163 P29375 1488 Phosphoserine 23186163 P29375 1598 Phosphoserine 17081983 P29375 1603 Phosphoserine 17081983 P29375 1666 Phosphoserine 23186163

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 5927 111862 - K Sumoylation 21693764 5927 111862 - K Ubiquitination 21139048 5927 111862 - K Ubiquitination 21890473 5927 111862 - K Ubiquitination 22505724 5927 111862 - K Ubiquitination 21963094 5927 111862 - K Sumoylation 25391492

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID KDM5A Homo sapiens (Human) 425 "425,GSGFPVKDGRRKI" 425:21890473 KDM5A Homo sapiens (Human) 425 "425,GSGFPVKDGRRKI" 425:21890473 KDM5A Homo sapiens (Human) 425 "425,GSGFPVKDGRRKI" 425:21890473 KDM5A Homo sapiens (Human) 425 "425,GSGFPVKDGRRKI" 425:21890473