Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 10 102256197 rs9420790 G A rs9420790 2.00E-06 HYDROCHLOROTHIAZIDE BLOOD GLUCOSE|TRIGLYCERIDES|ANTIHYPERTENSIVE AGENTS|NELL1 PROTEIN, HUMAN|NERVE TISSUE PROTEINS Thiazide-induced adverse metabolic effects in hypertensive patients HPOID:0000822 DOID:10763 A intron GWASdb_drug 10 102247408 rs2298075 C A rs2298075 2.00E-04 Breast cancer HPOID:0003002 DOID:1612 G missense GWASdb_trait 10 102256197 rs9420790 G A rs9420790 2.00E-06 Thiazide-induced adverse metabolic effects in hypertensive patients HPOID:0000822 DOID:10763 A intron GWASdb_trait 10 102259706 rs2273696 T G rs2273696 5.20E-04 Type 2 diabetes and 6 quantitative traits HPOID:0005978 DOID:9352 T intron GWASdb_trait 10 102279294 rs3750631 A G rs3750631 4.78E-05 Heart rate HPOID:0005150|HPOID:0001645|HPOID:0001644|HPOID:0011704|HPOID:0005110 DOID:10273 G intron GWASdb_trait

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000075826.16 SEC31B 610258