PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus TCP1 SEC31B 26186194 biogrid exp P P P P P P P P P P P P P P P P P P P BMI1 SEC31B 24457600 biogrid exp P P P P P P P P P P P P P P P P P P P YBX1 SEC31B 23986595 intact exp P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP SNW1 SEC31B 20467437 intact exp P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP CCT7 SEC31B 26186194 biogrid exp P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP SF3A2 SEC31B 17332742 biogrid,intact exp P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP CCT3 SEC31B 26186194 biogrid exp P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP MYC SEC31B 21150319 biogrid,i2d,intact exp P GP G GP P G GP GP GP P GP GP P P P P P GP P G GP GP CCT6B SEC31B 26186194 biogrid exp P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP ALDH5A1 SEC31B 26344197 biogrid exp P GP G GP GP G GP G GP GP P GP GP GP P G P P GP P G GP GP CCT4 SEC31B 26186194 biogrid exp, ortho P GP G G GP G GP G GP G GP G GP P G P G G GP GP CCT6A SEC31B 26186194 biogrid exp, ortho P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP CCT2 SEC31B 26186194 biogrid exp, ortho P GP G GP GP G GP G G GP P GP GP GP P G P P G P G GP GP RPLP0 SEC31B ortho P GP G G GP G GP G G G P G GP GP P G P G P G GP GP PSMD4 SEC31B ortho P GP G GP GP G GP G GP GP P GP GP GP P G P P GP P G GP GP DDX5 SEC31B ortho P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP RPS13 SEC31B ortho P P P P P P P P P P P P TMED2 SEC31B ortho P GP G GP GP G GP G GP GP P GP GP GP P P G P P G P G GP GP HSPA4 SEC31B ortho P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP SEC22B SEC31B ortho G G G G G G G G G G G G G G G G G DNAJA2 SEC31B ortho P GP G GP GP G GP G GP GP GP GP GP P P G P P GP P G GP GP TMED10 SEC31B ortho P GP G GP GP G GP G GP GP P GP GP GP P P G P P G P G GP GP CSNK1D SEC31B ortho P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP RPL3 SEC31B ortho P GP G GP GP G GP G GP GP P GP GP GP P P G P P G P G GP GP CAD SEC31B ortho P GP G GP GP G GP G GP GP P GP GP GP P P G P P P P G GP GP CSNK2A2 SEC31B ortho G G G G G G G G G G G G G G G G G PPP6C SEC31B ortho P GP G G GP G GP G GP G P GP GP GP P G P P GP P G GP GP PSMD2 SEC31B ortho P GP G GP GP G GP G GP GP P G GP GP P P G P P GP P G GP GP DDX54 SEC31B ortho GP G G GP G GP G GP G P G G GP P G P GP G GP GP RPL30 SEC31B ortho P GP G GP GP G GP G GP G P GP GP GP P G P P G P G GP GP SEC31B SEC31B ortho P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP ATP6V1B2 SEC31B ortho GP G GP GP G GP G GP GP P GP GP GP P G P P G P G GP GP HSPA5 SEC31B ortho P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP PRDX2 SEC31B ortho P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP RPL5 SEC31B ortho P P P P P P P P P P P P P P P P P P P SEC31B CORO1C ortho P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP CSNK2A1 SEC31B ortho P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP SEC13 SEC31B 21836163, 16082366 ortho, pred P GP G GP GP G GP G G G G GP GP P G P P G P G GP G SEC23A SEC31B 21836163, 16082366 ortho, pred G G G G G G G G G G G G G G G G G SEC24B SEC31B 21836163, 16082366 ortho, pred P GP G GP GP G GP G GP G P GP GP GP P G P P GP P G GP GP SEC31B SAR1A 21836163 ortho, pred P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP GBF1 SEC31B 21836163 pred P GP G G GP G GP G GP G GP GP GP P P G P P GP P G G GP SEC31B HCN2 21836163 pred G G G G SPINT2 SEC31B 21836163 pred P GP G GP GP G GP G GP GP P GP GP GP P P G P P P P G GP GP DMXL2 SEC31B 21836163 pred P GP G GP GP G GP G GP GP P GP GP GP P G P P P P G GP GP SRGAP2 SEC31B 21836163 pred G G G G G G G G G G SYN2 SEC31B 21836163 pred G G G G G G G G G G G G G G G G ARFIP1 SEC31B 21836163 pred P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP ARHGAP12 SEC31B 21836163 pred P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP SEC31B WDR7 21836163 pred P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP RFWD2 SEC31B 21836163 pred G G G GP G GP G G G G G GP G P G G GP G SRGAP1 SEC31B 21836163 pred GP GP G GP G GP GP G GP GP P G P G G GP KRT32 SEC31B 21836163 pred GP G GP P G P G P P GP P G P G GP PLEKHB2 SEC31B 21836163 pred G G G G G G G G G G G G G G G G G SCAMP5 SEC31B 21836163 pred GP G G GP G GP G GP G P G G GP P G P GP G GP GP APBA3 SEC31B 21836163 pred P GP G GP GP G GP G GP GP P GP GP GP P P G P GP P G GP GP SPINT1 SEC31B 21836163 pred P P P GP GP P P GP P P P G P P P P GP P SEC31B GMIP 21836163 pred P P G GP P GP P GP P GP GP P P P P P P P G GP P SEC24C SEC31B 21836163 pred P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP GOSR2 SEC31B 21836163 pred P GP G GP GP G GP G GP GP P GP GP GP P G P P GP P G GP GP ARHGAP22 SEC31B 21836163 pred P P GP P G P P G GP P P P P P P P DOC2A SEC31B 21836163 pred G G G G G CHID1 SEC31B 21836163 pred P GP G GP GP G GP G GP GP P GP GP GP P P G P P G P G GP GP IQGAP1 SEC31B 21836163 pred P GP G GP GP G GP G GP GP P GP GP GP P P G P P G P G GP GP CLTA SEC31B 21836163 pred P GP G GP GP G GP G GP GP P GP GP GP P G P P G P G GP GP TBL1X SEC31B 21836163 pred P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP SEC31B RPH3A 21836163 pred G G G GP G G G G G P G G GP G G G G SEC31B AP1M2 21836163 pred G G G G G G G G SEC31A SEC31B 21836163 pred P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP SEC23B SEC31B 16082366 pred P GP G G GP G GP G GP GP P GP GP GP P G P P GP P G GP GP SDF4 SEC31B 21836163 pred P GP G G GP G GP G GP GP G GP GP P G P P G P G GP GP ERGIC1 SEC31B 21836163 pred P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP COPE SEC31B 21836163 pred P GP G GP GP G GP G GP GP P G GP GP P G P P G P G GP GP MYO1G SEC31B 21836163 pred GP G GP GP G GP G GP G P GP G GP G P G G GP GP COG3 SEC31B 21836163 pred P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP HGFAC SEC31B 21836163 pred P P G G KRT35 SEC31B 21836163 pred SEC31B ARHGAP20 21836163 pred P GP P GP G GP G P GP P GP GP GP P P G P P P P GP GP CLTB SEC31B 21836163 pred P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP SEC31B ERGIC3 21836163 pred P GP G GP GP G GP G GP GP P GP GP GP P G P P G P G GP GP SEC24A SEC31B 21836163, 16082366 pred GP G G G G GP G GP GP P GP GP G P G P P G P G GP GP ARHGAP19 SEC31B 21836163 pred P GP G GP GP G GP G GP GP P G GP GP P P P P P G GP GP CST9 SEC31B 21836163 pred P P P P P P P P P P P P P P P P P P P STAMBPL1 SEC31B 21836163 pred GP G GP GP G GP G GP G P GP GP GP P G P P GP P G GP GP SEC31B DNAJC5B 21836163 pred G G G G G G G G G G G G G G G G G ATL2 SEC31B 21836163 pred GP G G GP G GP G GP G P G GP GP P G P GP P G GP GP ARHGAP25 SEC31B 21836163 pred G GP P GP G P GP P P G G GP P STX17 SEC31B 21836163 pred P GP G GP GP G GP G GP GP P GP GP GP P P G P P G P G GP GP AP1G2 SEC31B 21836163 pred P GP G GP GP G GP G GP GP P GP GP GP P P G P P P P G GP GP TMEM163 SEC31B 21836163 pred G GP G P G P G G GP G P P G GP GP EXOC6 SEC31B 21836163 pred P GP G GP GP G GP G GP GP P GP GP GP P P G P P GP P G GP GP HMHA1 SEC31B 21836163 pred G G GP P G P G GP G P P G G SEC24D SEC31B 21836163 pred P GP G GP P G GP GP GP P GP GP P P P G P P P G GP GP NUP133 SEC31B 21836163 pred G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P01106 Q9NQW1 affinity chromatography technology 21150319 physical association X 2 Q15428 Q9NQW1 affinity chromatography technology 17332742 physical association X 2 Q9NQW1 P35226 affinity chromatography technology 24457600 physical association X 2 Q9NQW1 tandem affinity purification 21150319 association C 49 Q9NQW1 anti tag coimmunoprecipitation 23986595 physical association C 45 Q15428 Q9NQW1 affinity chromatography technology 17332742 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality TCP1 SEC31B 26186194 0004 HT CCT6A SEC31B 26186194 0004 HT CCT4 SEC31B 26186194 0004 HT ALDH5A1 SEC31B 26344197 0401 HT Q59H77 SEC31B 26186194 0004 HT CCT6B SEC31B 26186194 0004 HT CCT7 SEC31B 26186194 0004 HT SEC31B HEL-S-100N 26186194 0004 HT TCP1 SEC31B 26186194 0004 HT CCT6A SEC31B 26186194 0004 HT CCT4 SEC31B 26186194 0004 HT ALDH5A1 SEC31B 26344197 0401 HT Q59H77 SEC31B 26186194 0004 HT CCT6B SEC31B 26186194 0004 HT CCT7 SEC31B 26186194 0004 HT SEC31B HEL-S-100N 26186194 0004 HT ALDH5A1 SEC31B 26344197 0401 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9NQW1 P17987 SEC31B TCP1 0.126 26186194 Q9NQW1 P40227 SEC31B CCT6A 0.126 26186194 Q9NQW1 P49368 SEC31B CCT3 0.126 26186194 Q9NQW1 P50991 SEC31B CCT4 0.126 26186194 Q9NQW1 P78371 SEC31B CCT2 0.126 26186194 Q9NQW1 Q92526 SEC31B CCT6B 0.126 26186194 Q9NQW1 Q99832 SEC31B CCT7 0.126 26186194 Q9NQW1 P01106 SEC31B MYC 0.236 21150319 Q9NQW1 Q13573 SEC31B SNW1 0.236 20467437 Q9NQW1 Q15428 SEC31B SF3A2 0.236 17332742

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 PPP6C SEC31B MI:0362 inference MI:0461 interaction database DNAJA2 SEC31B MI:0362 inference MI:0461 interaction database EED SEC31B MI:0362 inference MI:0461 interaction database SEC24D SEC31B MI:0362 inference MI:0461,MI:1106 interaction database,pathways database SEC31A SEC31B MI:0362 inference MI:1106 pathways database SEC24A SEC31B MI:0362 inference MI:0461,MI:1106 interaction database,pathways database SEC24B SEC31B MI:0362 inference MI:0461,MI:1106 interaction database,pathways database CPSF4 SEC31B MI:0362 inference MI:0461 interaction database HSPA4L SEC31B MI:0362 inference MI:0461 interaction database OTC SEC31B MI:0362 inference MI:0461 interaction database MYC SEC31B MI:0045 experimental interaction detection MI:0461 interaction database HIST1H2AB SEC31B MI:0362 inference MI:0461 interaction database RPLP2 SEC31B MI:0362 inference MI:0461 interaction database RPLP0 SEC31B MI:0362 inference MI:0461 interaction database ENO1 SEC31B MI:0362 inference MI:0461 interaction database HSP90AA1 SEC31B MI:0362 inference MI:0461 interaction database PFKM SEC31B MI:0362 inference MI:0461 interaction database HSP90AB1 SEC31B MI:0362 inference MI:0461 interaction database RPS17 SEC31B MI:0362 inference MI:0461 interaction database ENO2 SEC31B MI:0362 inference MI:0461 interaction database HIST1H2AG SEC31B MI:0362 inference MI:0461 interaction database UBC SEC31B MI:0362 inference MI:0461 interaction database HSPA1A SEC31B MI:0362 inference MI:0461 interaction database HSPA1B SEC31B MI:0362 inference MI:0461 interaction database HSPA5 SEC31B MI:0362 inference MI:0461 interaction database HSPA8 SEC31B MI:0362 inference MI:0461 interaction database IMPDH2 SEC31B MI:0362 inference MI:0461 interaction database ENO3 SEC31B MI:0362 inference MI:0461 interaction database ATP6V1B1 SEC31B MI:0362 inference MI:0461 interaction database H2AFX SEC31B MI:0362 inference MI:0461 interaction database HSPA6 SEC31B MI:0362 inference MI:0461 interaction database DDX5 SEC31B MI:0362 inference MI:0461 interaction database PFKL SEC31B MI:0362 inference MI:0461 interaction database TCP1 SEC31B MI:0045 experimental interaction detection MI:0461 interaction database RPL35A SEC31B MI:0362 inference MI:0461 interaction database RPL7 SEC31B MI:0362 inference MI:0461 interaction database CSNK2A2 SEC31B MI:0362 inference MI:0461 interaction database HIST1H2AD SEC31B MI:0362 inference MI:0461 interaction database IMPDH1 SEC31B MI:0362 inference MI:0461 interaction database ATP6V1B2 SEC31B MI:0362 inference MI:0461 interaction database RPS4Y1 SEC31B MI:0362 inference MI:0461 interaction database RPL13 SEC31B MI:0362 inference MI:0461 interaction database RPL10 SEC31B MI:0362 inference MI:0461 interaction database CAD SEC31B MI:0362 inference MI:0461 interaction database RPL12 SEC31B MI:0362 inference MI:0461 interaction database CORO1A SEC31B MI:0362 inference MI:0461 interaction database DNAJA1 SEC31B MI:0362 inference MI:0461 interaction database PRDX2 SEC31B MI:0362 inference MI:0461 interaction database HSPA1L SEC31B MI:0362 inference MI:0461 interaction database HSPA4 SEC31B MI:0362 inference MI:0461 interaction database BMI1 SEC31B MI:0045 experimental interaction detection MI:0461 interaction database CBS SEC31B MI:0362 inference MI:0461 interaction database RPL4 SEC31B MI:0362 inference MI:0461 interaction database PPP1CC SEC31B MI:0362 inference MI:0461 interaction database SREBF1 SEC31B MI:0362 inference MI:1106 pathways database RPL3 SEC31B MI:0362 inference MI:0461 interaction database CCT6A SEC31B MI:0045 experimental interaction detection MI:0461 interaction database RPL5 SEC31B MI:0362 inference MI:0461 interaction database RPS9 SEC31B MI:0362 inference MI:0461 interaction database CSNK1A1 SEC31B MI:0362 inference MI:0461 interaction database CSNK1D SEC31B MI:0362 inference MI:0461 interaction database CCT3 SEC31B MI:0045 experimental interaction detection MI:0461 interaction database CSNK1E SEC31B MI:0362 inference MI:0461 interaction database TMED10 SEC31B MI:0362 inference MI:0461 interaction database TAF6 SEC31B MI:0362 inference MI:0461 interaction database RPL14 SEC31B MI:0362 inference MI:0461 interaction database CCT4 SEC31B MI:0045 experimental interaction detection MI:0461 interaction database PAPOLA SEC31B MI:0362 inference MI:0461 interaction database SEC24C SEC31B MI:0362 inference MI:0461,MI:1106 interaction database,pathways database HSPA2 SEC31B MI:0362 inference MI:0461 interaction database PSMD4 SEC31B MI:0362 inference MI:0461 interaction database SEC13 SEC31B MI:0362 inference MI:0461,MI:1106 interaction database,pathways database NUP107 SEC31B MI:0362 inference MI:0461 interaction database ACTB SEC31B MI:0362 inference MI:0461 interaction database RPL37A SEC31B MI:0362 inference MI:0461 interaction database STXBP1 SEC31B MI:0362 inference MI:0461 interaction database RPS7 SEC31B MI:0362 inference MI:0461 interaction database PPP1CA SEC31B MI:0362 inference MI:0461 interaction database PPP1CB SEC31B MI:0362 inference MI:0461 interaction database RPS15A SEC31B MI:0362 inference MI:0461 interaction database RPS14 SEC31B MI:0362 inference MI:0461 interaction database RPS18 SEC31B MI:0362 inference MI:0461 interaction database RPS13 SEC31B MI:0362 inference MI:0461 interaction database RPS4X SEC31B MI:0362 inference MI:0461 interaction database ACTA2 SEC31B MI:0362 inference MI:0461 interaction database RPL23A SEC31B MI:0362 inference MI:0461 interaction database HIST1H4A SEC31B MI:0362 inference MI:0461 interaction database RPS24 SEC31B MI:0362 inference MI:0461 interaction database RPL30 SEC31B MI:0362 inference MI:0461 interaction database RPL31 SEC31B MI:0362 inference MI:0461 interaction database ACTG1 SEC31B MI:0362 inference MI:0461 interaction database ACTG2 SEC31B MI:0362 inference MI:0461 interaction database YBX1 SEC31B MI:0045 experimental interaction detection MI:0461 interaction database CSNK2B SEC31B MI:0362 inference MI:0461 interaction database ACTC1 SEC31B MI:0362 inference MI:0461 interaction database EEF1A1 SEC31B MI:0362 inference MI:0461 interaction database ACTA1 SEC31B MI:0362 inference MI:0461 interaction database CSNK2A1 SEC31B MI:0362 inference MI:0461 interaction database CCT2 SEC31B MI:0045 experimental interaction detection MI:0461 interaction database PFKP SEC31B MI:0362 inference MI:0461 interaction database RPL18A SEC31B MI:0362 inference MI:0461 interaction database EEF1A2 SEC31B MI:0362 inference MI:0461 interaction database RPL18 SEC31B MI:0362 inference MI:0461 interaction database CPSF1 SEC31B MI:0362 inference MI:0461 interaction database SCAP SEC31B MI:0362 inference MI:1106 pathways database SREBF2 SEC31B MI:0362 inference MI:1106 pathways database CSTF3 SEC31B MI:0362 inference MI:0461 interaction database PRDX4 SEC31B MI:0362 inference MI:0461 interaction database PSMD2 SEC31B MI:0362 inference MI:0461 interaction database SNW1 SEC31B MI:0045 experimental interaction detection MI:0461 interaction database TMED2 SEC31B MI:0362 inference MI:0461 interaction database SF3A2 SEC31B MI:0045 experimental interaction detection MI:0461 interaction database SEC23A SEC31B MI:0362 inference MI:0461,MI:1106 interaction database,pathways database SEC23B SEC31B MI:0362 inference MI:0461,MI:1106 interaction database,pathways database STXBP2 SEC31B MI:0362 inference MI:0461 interaction database HIST2H2AC SEC31B MI:0362 inference MI:0461 interaction database HIST2H2AA3 SEC31B MI:0362 inference MI:0461 interaction database CORO6 SEC31B MI:0362 inference MI:0461 interaction database HIST3H2A SEC31B MI:0362 inference MI:0461 interaction database HIST2H2AB SEC31B MI:0362 inference MI:0461 interaction database RPS4Y2 SEC31B MI:0362 inference MI:0461 interaction database DDX54 SEC31B MI:0362 inference MI:0461 interaction database DNAJA4 SEC31B MI:0362 inference MI:0461 interaction database CCT6B SEC31B MI:0045 experimental interaction detection MI:0461 interaction database HSPH1 SEC31B MI:0362 inference MI:0461 interaction database CORO2A SEC31B MI:0362 inference MI:0461 interaction database RPL3L SEC31B MI:0362 inference MI:0461 interaction database CLP1 SEC31B MI:0362 inference MI:0461 interaction database HIST1H2AC SEC31B MI:0362 inference MI:0461 interaction database SEH1L SEC31B MI:0362 inference MI:0461 interaction database HIST1H2AH SEC31B MI:0362 inference MI:0461 interaction database RPL10L SEC31B MI:0362 inference MI:0461 interaction database HIST1H2AA SEC31B MI:0362 inference MI:0461 interaction database HIST1H4G SEC31B MI:0362 inference MI:0461 interaction database CCT7 SEC31B MI:0045 experimental interaction detection MI:0461 interaction database HIST1H2AJ SEC31B MI:0362 inference MI:0461 interaction database CORO1B SEC31B MI:0362 inference MI:0461 interaction database H2AFJ SEC31B MI:0362 inference MI:0461 interaction database PAPOLG SEC31B MI:0362 inference MI:0461 interaction database WDR33 SEC31B MI:0362 inference MI:0461 interaction database SSU72 SEC31B MI:0362 inference MI:0461 interaction database SEC31B SAR1A MI:0362 inference MI:0461,MI:1106 interaction database,pathways database SEC31B PAPOLB MI:0362 inference MI:0461 interaction database SEC31B CPSF3 MI:0362 inference MI:0461 interaction database SEC31B CORO1C MI:0362 inference MI:0461 interaction database SEC31B CORO2B MI:0362 inference MI:0461 interaction database SEC31B RPL36 MI:0362 inference MI:0461 interaction database SEC31B SAR1B MI:0362 inference MI:0461,MI:1106 interaction database,pathways database