PTM - CPLM Gene Name UniProt ID Type Position Code CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 Ubiquitination 121 K

PTM - dbPAF Gene Name UniProt ID Position Type Species CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 13 S Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 15 Y Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 22 Y Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 287 S Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 29 S Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 31 T Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 343 T Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 344 S Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 35 T Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 356 Y Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 362 S Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 376 Y Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 387 S Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 389 T Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 392 S Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 393 T Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 398 S Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 399 S Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 418 S Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 422 S Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 424 T Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 432 S Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 436 S Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 439 S Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 441 S Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 444 S Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 45 S Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 523 Y Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 547 S Homo sapiens(Human) CYLD; CYLD1; KIAA0849; HSPC057 Q9NQC7 772 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q9NQC7 S3-p Phosphorylation _____MSsGLWSQEK Q9NQC7 T12-p Phosphorylation LWSQEKVtsPyWEER Q9NQC7 S13-p Phosphorylation WSQEKVtsPyWEERI Q9NQC7 Y15-p Phosphorylation QEKVtsPyWEERIFy Q9NQC7 Y22-p Phosphorylation yWEERIFyLLLQECs Q9NQC7 S29-p Phosphorylation yLLLQECsVtDKQtQ Q9NQC7 T31-p Phosphorylation LLQECsVtDKQtQKL Q9NQC7 T35-p Phosphorylation CsVtDKQtQKLLKVP Q9NQC7 S45-p Phosphorylation LLKVPkGsIGQYIQD Q9NQC7 S287-p Phosphorylation FDGVQLCsFACVEST Q9NQC7 T343-p Phosphorylation KPKATGStsDPGNRN Q9NQC7 S344-p Phosphorylation PKATGStsDPGNRNR Q9NQC7 Y356-p Phosphorylation RNRSELFyTLNGSsV Q9NQC7 S362-p Phosphorylation FyTLNGSsVDSQPQs Q9NQC7 S369-p Phosphorylation sVDSQPQsKSKNTWy Q9NQC7 Y376-p Phosphorylation sKSKNTWyIDEVAED Q9NQC7 S387-p Phosphorylation VAEDPAKsLtEISTD Q9NQC7 T389-p Phosphorylation EDPAKsLtEISTDFD Q9NQC7 S399-p Phosphorylation STDFDRSsPPLQPPP Q9NQC7 S409-p Phosphorylation LQPPPVNsLTTENRF Q9NQC7 S418-p Phosphorylation TTENRFHsLPFsLtK Q9NQC7 S422-p Phosphorylation RFHsLPFsLtKMPNT Q9NQC7 T424-p Phosphorylation HsLPFsLtKMPNTNG Q9NQC7 S432-p Phosphorylation KMPNTNGsIGHsPLs Q9NQC7 S436-p Phosphorylation TNGsIGHsPLsLsAQ Q9NQC7 S439-p Phosphorylation sIGHsPLsLsAQsVM Q9NQC7 S441-p Phosphorylation GHsPLsLsAQsVMEE Q9NQC7 S444-p Phosphorylation PLsLsAQsVMEELNT Q9NQC7 Y523-p Phosphorylation GTFRGTRyFTCALKK Q9NQC7 S547-p Phosphorylation RPDSRFAsLQPVsNQ Q9NQC7 S552-p Phosphorylation FAsLQPVsNQIERCN Q9NQC7 S560-p Phosphorylation NQIERCNsLAFGGYL Q9NQC7 S772-p Phosphorylation LFKKIFPsLELNITD Q9NQC7 K43-ub Ubiquitination QKLLKVPkGsIGQYI Q9NQC7 K121-ub Ubiquitination KNRNRLSkGLQIDVG Q9NQC7 K141-ub Ubiquitination QLRSGEEkFPGVVRF Q9NQC7 K318-ub Ubiquitination TQERRPPkLAFMSRG

PTM - dbPTM UniProt ID Position Code Type Resources References Q9NQC7 399 S Phosphorylation Swiss-Prot 1010711 17081983 Q9NQC7 418 S Phosphorylation Swiss-Prot 1010711 15870263 Q9NQC7 393 T Phosphorylation PhosphoELM.10011 18669648 Q9NQC7 399 S Phosphorylation Phosphositeplus.1010730 21659604 Q9NQC7 418 S Phosphorylation Phosphositeplus.1010730 15870263;19276368 Q9NQC7 422 S Phosphorylation Phosphositeplus.1010730 15870263 Q9NQC7 432 S Phosphorylation Phosphositeplus.1010730 15870263 Q9NQC7 436 S Phosphorylation Phosphositeplus.1010730 15870263 Q9NQC7 439 S Phosphorylation Phosphositeplus.1010730 15870263 Q9NQC7 441 S Phosphorylation Phosphositeplus.1010730 15870263 Q9NQC7 444 S Phosphorylation Phosphositeplus.1010730 15870263 Q9NQC7 356 Y Phosphorylation Phosphositeplus.1010730 20090780 Q9NQC7 399 S Phosphorylation HPRD 9.0 17081983 Q9NQC7 393 T Phosphorylation HPRD 9.0 18669648 Q9NQC7 399 S Phosphorylation SysPTM 1.1 17081983

PTM - HPRD Symbol Position Code Type References CYLD 390 T Phosphorylation 18669648 CYLD 393 T Phosphorylation 18669648 CYLD 396 S Phosphorylation 17081983 CYLD 399 S Phosphorylation 17081983

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q9NQC7 393 T 18669648 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q9NQC7 387 Phosphoserine 24275569 Q9NQC7 418 Phosphoserine 23186163;15870263 Q9NQC7 422 Phosphoserine 23186163

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 1540 107920 - K Ubiquitination 21139048 1540 107920 - K Ubiquitination 22505724 1540 107920 - K Ubiquitination 18977328 1540 107920 - K Ubiquitination 23000965