PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus BACH1 ANAPC5 21988832 biogrid,intact exp GP GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G GTF2E1 ANAPC5 26344197 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HECW2 ANAPC5 24163370 biogrid exp GP GP G G GP GP G GP GP G GP G GP G G P GP P GP G GP GP GP GP GP G GP GP ANAPC5 TRIM33 23160376 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G SH3KBP1 ANAPC5 19531213 biogrid exp G G G G GP GP G G G G G G G GP G G GP G G G GP G G G G GP G G G TTLL1 ANAPC5 26186194 biogrid exp GP GP G P GP G GP P G GP P GP P G GP GP GP P G P GP GP GP P GP GP G NFYC ANAPC5 20936779 i2d exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G LATS2 ANAPC5 24255178 biogrid exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G USP37 ANAPC5 21596315 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G P GP GP P G GP G GP G P G GP GP KNG1 ANAPC5 26186194 biogrid exp GP G G P PTEN ANAPC5 21241890 biogrid,intact exp GP GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP G GP G GP GP GP GP G NOTCH1 ANAPC5 23022380 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ANAPC15 ANAPC5 26496610,23007861 biogrid,intact exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TFDP1 ANAPC5 25368385 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G ESR2 ANAPC5 21182203 intact exp GP GP G GP GP G GP GP GP GP GP GP G P GP GP GP G GP P GP GP GP GP GP GP OFD1 ANAPC5 26638075 biogrid,intact exp GP GP G G GP GP G GP GP G GP G GP G G GP GP GP GP G GP GP GP GP GP GP GP GP G SMARCAD1 ANAPC5 21549307 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G CFAP97 ANAPC5 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ANAPC5 AXIN2 19888210 i2d exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ANAPC5 ANAPC5 17721511 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MAPK6 ANAPC5 21900206 biogrid,mint,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ANAPC5 PHF8 23979597 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PENK ANAPC5 26186194 biogrid exp GP GP G G GP GP G GP GP G P GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CREBBP ANAPC5 16319895 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G XPO1 ANAPC5 26673895 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MAGIX ANAPC5 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G GRAP2 ANAPC5 26186194 biogrid exp P P P P P P P P P P P P P P P TP53BP1 ANAPC5 22990118 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PABPC1 ANAPC5 15082755 hprd,biogrid,bci exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G BUB3 ANAPC5 20360068 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MDC1 ANAPC5 17827148,22990118 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MED19 ANAPC5 15175163 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PIFO ANAPC5 26186194 biogrid exp GP G G G GP GP G GP P GP G G GP G G GP G GP GP GP GP GP GP G ZBTB16 ANAPC5 16169070 hprd,biogrid,i2d,mint,intact exp G GP G G G GP G G GP G G G GP G G GP GP G GP G G GP GP G GP G G GP G SOX2 ANAPC5 23667531 biogrid exp P P G P GP G P GP G P P GP P GP GP P G P GP P GP P GP GP G TGFBR1 ANAPC5 15761153 hprd,i2d exp GP G G G GP GP G GP GP G GP GP GP G G GP GP G G G G G G G GP G GP G G EP300 ANAPC5 16319895 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G E2F1 ANAPC5 22580462,25368385 biogrid exp P GP G G GP GP G GP GP G GP GP GP GP GP GP GP GP G P P GP P GP P GP GP G CUL4A ANAPC5 21145461 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CDT1 ANAPC5 18162579 biogrid exp P P G GP P GP GP P P P P GP P GP GP G P P P P GP P GP P G PAXIP1 ANAPC5 22990118 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ANAPC5 ANAPC2 10922056,22939629,12956947,20360068, 25402006, 21836163 biogrid,intact exp, pred GP GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP GP G GP GP GP GP G ANAPC13 ANAPC5 22939629,20360068, 25402006 biogrid,intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G ANAPC5 FBXO5 16921029, 25402006 biogrid exp, pred P P G GP P P GP P P P P GP P GP P P P P P GP GP P P CDC23 ANAPC5 22939629,26496610,20360068, 25402006, 21836163 biogrid,intact exp, pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SMURF2 ANAPC5 15761153, 21836163 hprd,i2d,bci exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CDC20 ANAPC5 23160376,20360068, 25402006, 21836163 biogrid,intact exp, pred P G GP G GP P P GP G G P GP P GP GP BUB1B ANAPC5 20360068, 25402006 intact exp, pred P P G GP P GP GP P P P GP GP P GP P GP P P P GP P GP GP G ANAPC16 ANAPC5 26344197,20360068, 25402006 biogrid,intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ANAPC5 FZR1 12956947,23160376, 25402006 biogrid exp, pred G GP G G G GP G GP GP G GP GP GP G G GP GP G P G G GP G GP GP G GP GP G CDC26 ANAPC5 20360068, 25402006 intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G G GP GP GP GP GP GP GP G CDC16 ANAPC5 26344197,22939629,26496610,20360068, 25402006, 21836163 biogrid,intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G ANAPC7 ANAPC5 22939629,23160376,20360068, 25402006, 21836163 biogrid,intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G ANAPC5 ANAPC4 25490258,26083744,26344197,22939629,12956947,25043029,23078409,20360068, 25402006, 21836163 biogrid,intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ANAPC1 ANAPC5 11076961,26344197,22939629,12956947,20360068, 25402006 biogrid,intact exp, pred P P P P P P P P P P P P P P P P P P P CDC27 ANAPC5 21241890,22939629,20686030,12956947,22792066,20360068,10922056,14657031,15082755,16364912,21043528,22193957, 25402006, 21836163 biogrid,intact exp, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SMURF1 ANAPC5 15761153, 21836163 hprd,i2d exp, pred G GP G G GP GP G G GP G GP G GP G G G GP GP G G GP G G G G GP G GP G NCAM1 ANAPC5 ortho G GP G G G GP G GP GP G G G G G G G GP GP G G G G G G G GP GP G CTNNB1 ANAPC5 ortho GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP G GP G GP GP G CCNB1 ANAPC5 25402006 pred P G G GP G G G GP G P GP GP G G G G GP G P GP P GP GP PSMD4 ANAPC5 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G NEK2 ANAPC5 25402006 pred P G G P P GP P P GP P P P G P P GP P P GP PAN2 ANAPC5 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ANAPC5 PRKAB1 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G PSMB8 ANAPC5 21836163 pred PSMB7 ANAPC5 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMA5 ANAPC5 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G BANF1 ANAPC5 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2C ANAPC5 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MAD2L1 ANAPC5 25402006 pred P G G P P GP P P P GP G GP P G P P GP P GP GP GP GP EIF3G ANAPC5 21836163 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMD1 ANAPC5 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMC1 ANAPC5 21836163 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G PSMB3 ANAPC5 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ANAPC5 ANAPC10 25402006, 21836163 pred GP G G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP GP GP GP G PTTG1 ANAPC5 25402006 pred GP G G G GP G G G GP G G G G GP G GP G G G G GP G G G GP GP G GP G PSMA4 ANAPC5 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ANAPC11 ANAPC5 25402006, 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SKP1 ANAPC5 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G PSMA6 ANAPC5 21836163 pred P P P P P P P P P P P P P P P P P P P P PCBP2 ANAPC5 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MAD2L2 ANAPC5 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G TMEM147 ANAPC5 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PSMB6 ANAPC5 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G EIF4G1 ANAPC5 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMA1 ANAPC5 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMB4 ANAPC5 21836163 pred G GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G G GP GP GP GP G PSMA7 ANAPC5 21836163 pred G GP G G G GP G G GP G GP GP G G G GP GP G GP G GP G G G GP G GP GP G NDUFB5 ANAPC5 21836163 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G EDF1 ANAPC5 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G APC2 ANAPC5 25402006 pred G G G G G G G G G G G G G PSMC4 ANAPC5 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PIN1 ANAPC5 25402006 pred G GP G G GP GP G G GP G G G G GP G G GP G P G P GP G G G G GP GP G ANAPC5 PSMD13 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G PSMC3 ANAPC5 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SCAMP3 ANAPC5 21836163 pred G G G G G GP G GP G G GP G GP GP G G GP G GP G G G G GP G G GP GP G CCNA1 ANAPC5 25402006 pred G G G G G G G G G G G G G G G PSMD9 ANAPC5 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PCBP1 ANAPC5 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CDH1 ANAPC5 25402006 pred GP G G G GP GP GP GP G G GP G GP G GP GP GP GP G GP G PSMB5 ANAPC5 21836163 pred G GP G G G GP G G GP G GP G G G G G GP G GP G G G GP G G G GP GP G RPS5 ANAPC5 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RPS27A ANAPC5 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMB10 ANAPC5 21836163 pred GP G G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP G G GP GP GP G G CUL7 ANAPC5 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSME3 ANAPC5 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G EIF3C ANAPC5 21836163 pred P GP P P P GP GP GP P GP GP P GP P P GP GP P P GP GP GP G PSMC2 ANAPC5 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ACO2 ANAPC5 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9UJX4 - 11076961 - C 8 Q9UJX4 - 15175163 - C 122 Q9UJX4 coimmunoprecipitation 9469815 association C 8 Q9UJX4 coimmunoprecipitation 10318877 association C 9 Q9UJX4 electron tomography 25043029 physical association C 13 Q9UJX4 electron tomography 25043029 physical association C 16 Q9UJX4 anti tag coimmunoprecipitation 21186364 - C 11 Q9UJX4 electron tomography 25043029 physical association C 14 P34244 Q9UJX4 anti tag coimmunoprecipitation 21186364 physical association X 2 Q9UJX4 anti tag coimmunoprecipitation 21241890 association C 5 Q9UJX4 anti bait coimmunoprecipitation 21241890 association C 5 Q9UJX4 anti bait coimmunoprecipitation 21241890 association C 5 Q9UJX4 anti tag coimmunoprecipitation 24255178 association C 32 Q9UJX4 anti tag coimmunoprecipitation 15175163 association C 113 Q9UJX4 tandem affinity purification 20360068 association C 17 Q9UJX4 tandem affinity purification 20360068 association C 11 Q9UJX4 tandem affinity purification 20360068 association C 8 Q9UJX4 tandem affinity purification 20360068 physical association C 22 Q9UJX4 proximity-dependent biotin identification 24255178 colocalization C 50 Q9UJX4 tandem affinity purification 20360068 physical association C 10 Q9UJX4 tandem affinity purification 20360068 association C 13 Q9UJX4 tandem affinity purification 20360068 physical association C 23 Q9UJX4 tandem affinity purification 20360068 association C 18 O14867 Q9UJX4 two hybrid array 21988832 physical association X 2 Q9UJX4 anti bait coimmunoprecipitation 20360068 association C 8 Q9UJX4 anti bait coimmunoprecipitation 20360068 association C 8 Q9UJX4 tandem affinity purification 20360068 association C 20 Q9UJX4 tandem affinity purification 20360068 physical association C 30 Q9UJX4 tandem affinity purification 20360068 physical association C 19 Q9UJX4 tandem affinity purification 20360068 association C 15 Q9UJX4 tandem affinity purification 20360068 association C 14 Q9UJX4 pull down 19124460 association C 14 Q9UJX4 tandem affinity purification 20360068 physical association C 19 Q9UJX4 A0A024R3C6 two hybrid pooling approach 16169070 physical association X 2 Q9UJX4 Q16659 two hybrid 21900206 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B CREBBP ANAPC5 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16319895 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_124966|BIOGRID_124959 bait|bait prey|prey MDC1 ANAPC5 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17827148,22990118 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_246158|BIOGRID_137174 bait|bait prey|prey CDC20 ANAPC5 MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0676(tandem affinity purification) 12956947,20360068,23160376 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0914(association) (intact)|(intact)|(intact)|(biogrid)|(biogrid)|(intact) UniProt_170234|UniProt_106539|UniProt_106543|BIOGRID_85260|BIOGRID_248549|UniProt_170230 bait|prey|bait|bait|bait|prey prey|bait|prey|prey|prey|bait UBC ANAPC5 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology) 21139048,21890473,21906983,21963094,21987572,22053931,22505724 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_173159|BIOGRID_224345|BIOGRID_178610|BIOGRID_264068|BIOGRID_222046|BIOGRID_162808|BIOGRID_169296 bait|bait|bait|bait|bait|bait|bait prey|prey|prey|prey|prey|prey|prey CDC27 ANAPC5 MI:0493(in vivo)|MI:0493(in vivo)|MI:0676(tandem affinity purification)|MI:0493(in vivo)|MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0004(affinity chromatography technology)|MI:0401(biochemical)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0401(biochemical)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0493(in vivo) 10318877,10500174,10922056,12956947,14657031,15082755,16364912,16648845,20360068,21043528,21241890,22193957,22792066,22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|-|MI:0914(association)|-|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|- MI:0468(hprd)|MI:0468(hprd)|(intact)|MI:0468(hprd)|(intact)|(intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd) HPRD_39295|HPRD_39519|UniProt_106539|HPRD_39294|UniProt_170230|UniProt_106537|BIOGRID_199766|BIOGRID_230284|BIOGRID_251977|BIOGRID_199375|BIOGRID_207327|BIOGRID_114250|BIOGRID_159909|BIOGRID_86727|BIOGRID_85258|BIOGRID_132829|HPRD_39911 -|-|prey|-|prey|bait|bait|prey|bait|bait|bait|bait|bait|prey|bait|bait|- -|-|bait|-|bait|prey|prey|bait|prey|prey|prey|prey|prey|bait|prey|prey|- ANAPC5 PHF8 MI:0004(affinity chromatography technology) 23979597 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_289134 prey bait HDAC1 ANAPC5 MI:0004(affinity chromatography technology) 22318606 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0799(additive genetic interaction defined by inequality) (biogrid) BIOGRID_192628 bait prey PABPC1 ANAPC5 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0492(in vitro)|MI:0018(two hybrid) 15082755 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|-|MI:0407(direct interaction) (biogrid)|(biogrid)|MI:0468(hprd)|(biogrid) BIOGRID_77969|BIOGRID_86726|HPRD_13218|BIOGRID_86725 prey|prey|-|prey bait|bait|-|bait PAXIP1 ANAPC5 MI:0004(affinity chromatography technology) 22990118 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_246366 bait prey LATS2 ANAPC5 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 24255178 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_292922|BIOGRID_292923 bait|bait prey|prey ANAPC5 ANAPC2 MI:0493(in vivo)|MI:0492(in vitro)|MI:0493(in vivo)|MI:0676(tandem affinity purification)|MI:0493(in vivo)|MI:0676(tandem affinity purification)|MI:0492(in vitro)|MI:0096(pull down)|MI:0401(biochemical) 10318877,10500174,10922056,12956947,20360068,22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|-|-|MI:0914(association)|-|MI:0914(association)|-|MI:0407(direct interaction)|MI:0403(colocalization) MI:0468(hprd)|MI:0468(hprd)|MI:0468(hprd)|(intact)|MI:0468(hprd)|(intact)|MI:0468(hprd)|(biogrid)|(biogrid) HPRD_39295|HPRD_39949|HPRD_39519|UniProt_106539|HPRD_39294|UniProt_170230|HPRD_39948|BIOGRID_84799|BIOGRID_230283 -|-|-|bait|-|bait|-|prey|prey -|-|-|prey|-|prey|-|bait|bait ANAPC5 ANAPC4 MI:0493(in vivo)|MI:0492(in vitro)|MI:0493(in vivo)|MI:0676(tandem affinity purification)|MI:0493(in vivo)|MI:0676(tandem affinity purification)|MI:0492(in vitro)|MI:0096(pull down)|MI:0096(pull down)|MI:0401(biochemical)|MI:0493(in vivo) 10318877,10500174,10922056,12956947,16648845,20360068,22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|-|-|MI:0914(association)|-|MI:0914(association)|-|MI:0915(physical association)|MI:0407(direct interaction)|MI:0403(colocalization)|- MI:0468(hprd)|MI:0468(hprd)|MI:0468(hprd)|(intact)|MI:0468(hprd)|(intact)|MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd) HPRD_39295|HPRD_39949|HPRD_39519|UniProt_106539|HPRD_39294|UniProt_170230|HPRD_39948|BIOGRID_85259|BIOGRID_84800|BIOGRID_230207|HPRD_39911 -|-|-|bait|-|bait|-|prey|prey|prey|- -|-|-|prey|-|prey|-|bait|bait|bait|- ANAPC5 FBXO5 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16921029 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_221070|BIOGRID_221077 prey|prey bait|bait SOX2 ANAPC5 MI:0004(affinity chromatography technology) 23667531 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_274978 bait prey ANAPC5 TRIM33 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 23160376 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_248545|BIOGRID_248538 prey|bait bait|prey ANAPC5 FZR1 MI:0493(in vivo)|MI:0096(pull down) 10500174,12956947 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction) MI:0468(hprd)|(biogrid) HPRD_39294|BIOGRID_84795 -|bait -|prey EP300 ANAPC5 MI:0004(affinity chromatography technology) 16319895 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_124958 bait prey USP37 ANAPC5 MI:0004(affinity chromatography technology) 21596315 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_201401 bait prey TP53BP1 ANAPC5 MI:0004(affinity chromatography technology) 22990118 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_246454 bait prey APC2 ANAPC5 MI:0096(pull down)|MI:0493(in vivo) 12956947,16648845 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_85257|HPRD_39911 bait|- prey|- E2F1 ANAPC5 MI:0004(affinity chromatography technology) 22580462 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_188013 bait prey SH3KBP1 ANAPC5 MI:0004(affinity chromatography technology) 19531213 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_191157 bait prey HECW2 ANAPC5 MI:0004(affinity chromatography technology) 24163370 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_293915 bait prey PTEN ANAPC5 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21241890 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(biogrid)|(biogrid) UniProt_112252|UniProt_112253|UniProt_112246|BIOGRID_251969|BIOGRID_251973 bait|prey|bait|bait|bait prey|prey|prey|prey|prey SMURF2 ANAPC5 MI:0493(in vivo) 15761153 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_17269 - - PTTG1 ANAPC5 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20080579,22193957 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_146747|BIOGRID_159930 prey|prey bait|bait CDC16 ANAPC5 MI:0493(in vivo)|MI:0493(in vivo)|MI:0676(tandem affinity purification)|MI:0401(biochemical)|MI:0493(in vivo)|MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0493(in vivo) 10318877,10500174,10922056,16648845,20360068,22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|-|MI:0914(association)|MI:0403(colocalization)|-|MI:0914(association)|MI:0914(association)|MI:0914(association)|- MI:0468(hprd)|MI:0468(hprd)|(intact)|(biogrid)|MI:0468(hprd)|(intact)|(intact)|(intact)|MI:0468(hprd) HPRD_39295|HPRD_39519|UniProt_106539|BIOGRID_230537|HPRD_39294|UniProt_170231|UniProt_170230|UniProt_106540|HPRD_39911 -|-|prey|prey|-|bait|prey|bait|- -|-|bait|bait|-|prey|bait|prey|- SMARCAD1 ANAPC5 MI:0004(affinity chromatography technology) 21549307 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_165300 bait prey CUL4A ANAPC5 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_202966 bait prey BACH1 ANAPC5 MI:0004(affinity chromatography technology)|MI:0397(two hybrid array) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_287675|UniProt_117353 prey|unspecified role bait|unspecified role UBE2C ANAPC5 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20080579,22193957 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_221603|BIOGRID_222939 prey|prey bait|bait ANAPC7 ANAPC5 MI:0493(in vivo)|MI:0493(in vivo)|MI:0676(tandem affinity purification)|MI:0493(in vivo)|MI:0676(tandem affinity purification)|MI:0401(biochemical)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0493(in vivo) 10318877,10500174,10922056,12956947,16648845,20360068,22939629,23160376 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|-|MI:0914(association)|-|MI:0914(association)|MI:0403(colocalization)|MI:0407(direct interaction)|MI:0915(physical association)|- MI:0468(hprd)|MI:0468(hprd)|(intact)|MI:0468(hprd)|(intact)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd) HPRD_39295|HPRD_39519|UniProt_106539|HPRD_39294|UniProt_170230|BIOGRID_230309|BIOGRID_85057|BIOGRID_248543|HPRD_39911 -|-|prey|-|prey|prey|prey|bait|- -|-|bait|-|bait|bait|bait|prey|- ANAPC13 ANAPC5 MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0401(biochemical) 20360068,22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0403(colocalization) (intact)|(intact)|(biogrid) UniProt_170235|UniProt_106544|BIOGRID_232971 bait|bait|bait prey|prey|prey NOTCH1 ANAPC5 MI:0004(affinity chromatography technology) 23022380 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_246677 bait prey CCNB1 ANAPC5 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20080579,22193957 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_159922|BIOGRID_146760 prey|prey bait|bait TGFBR1 ANAPC5 MI:0493(in vivo) 15761153 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_17270 - - ANAPC1 ANAPC5 MI:0493(in vivo)|MI:0493(in vivo)|MI:0676(tandem affinity purification)|MI:0493(in vivo)|MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0492(in vitro)|MI:0401(biochemical)|MI:0401(biochemical)|MI:0096(pull down)|MI:0676(tandem affinity purification)|MI:0493(in vivo) 10318877,10500174,10922056,11076961,12956947,16648845,20360068,22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|-|MI:0914(association)|-|MI:0914(association)|MI:0914(association)|-|MI:0403(colocalization)|MI:0914(association)|MI:0407(direct interaction)|MI:0914(association)|- MI:0468(hprd)|MI:0468(hprd)|(intact)|MI:0468(hprd)|(intact)|(intact)|MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid)|(intact)|MI:0468(hprd) HPRD_39295|HPRD_39519|UniProt_106539|HPRD_39294|UniProt_170229|UniProt_170230|HPRD_39948|BIOGRID_230266|BIOGRID_105785|BIOGRID_84798|UniProt_106538|HPRD_39911 -|-|prey|-|bait|prey|-|bait|bait|bait|bait|- -|-|bait|-|prey|bait|-|prey|prey|prey|prey|- UBE2D1 ANAPC5 MI:0004(affinity chromatography technology) 20080579 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_222952 prey bait CDT1 ANAPC5 MI:0004(affinity chromatography technology) 18162579 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_117698 bait prey ZBTB16 ANAPC5 MI:0492(in vitro)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|MI:0471(mint)|MI:0471(mint)|(intact) HPRD_30013|BIOGRID_93339|MINT_36372|MINT_65488|UniProt_155901 -|prey|prey|prey|prey -|bait|bait|bait|bait CDC23 ANAPC5 MI:0493(in vivo)|MI:0493(in vivo)|MI:0676(tandem affinity purification)|MI:0493(in vivo)|MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0401(biochemical)|MI:0676(tandem affinity purification)|MI:0493(in vivo) 10318877,10500174,10922056,16648845,20360068,22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|-|MI:0914(association)|-|MI:0914(association)|MI:0914(association)|MI:0403(colocalization)|MI:0914(association)|- MI:0468(hprd)|MI:0468(hprd)|(intact)|MI:0468(hprd)|(intact)|(intact)|(biogrid)|(intact)|MI:0468(hprd) HPRD_39295|HPRD_39519|UniProt_106539|HPRD_39294|UniProt_170230|UniProt_106541|BIOGRID_230514|UniProt_170232|HPRD_39911 -|-|prey|-|prey|bait|prey|bait|- -|-|bait|-|bait|prey|bait|prey|- SMURF1 ANAPC5 MI:0493(in vivo) 15761153 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_17267 - - CDH1 ANAPC5 MI:0004(affinity chromatography technology) 23160376 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_248552 bait prey ANAPC15 ANAPC5 MI:0004(affinity chromatography technology) 23007861 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_247774 bait prey

PPI - HINT Gene A Gene B PMID Method Quality B4DL80 ANAPC5 22792066,16364912,10922056,22193957,15082755,12956947,14657031 0004,0004,0004,0004,0004,0004,0004 LC OFD1 ANAPC5 26638075,26638075 1314,1313 HT GRAP2 ANAPC5 26186194 0004 HT TTLL1 ANAPC5 26186194 0004 HT KNG1 ANAPC5 26186194 0004 HT PENK ANAPC5 26186194 0004 HT GTF2E1 ANAPC5 26344197 0401 HT CDC27 ANAPC5 26811472,20360068,20360068,16364912,10922056,20686030,21241890,25306918,22193957,15082755,27114510,21241890,14657031,12956947,21043528,22939629,22792066 0004,0006,0676,0004,0004,0004,0004,0004,0004,0004,0004,0006,0004,0004,0401,0401,0004 LC,HT ANAPC15 ANAPC5 26496610,23007861,26496610 0007,0004,0004 HT,LC CDC20 ANAPC5 23160376,20360068,12956947,27114510,25306918,26811472 0004,0676,0096,0004,0004,0004 LC CDC16 ANAPC5 26496610,20360068,26344197,26496610,22939629 0007,0676,0401,0004,0401 HT,LC CUL4A ANAPC5 21145461 0004 HT MDC1 ANAPC5 22990118,17827148 0004,0004 LC USP37 ANAPC5 26299517,21596315 1313,0004 LC PIFO ANAPC5 26186194 0004 HT ANAPC16 ANAPC5 26344197,20360068,20360068 0401,0676,0006 HT,LC ANAPC13 ANAPC5 20360068,22939629 0676,0401 LC,HT Q9BSD8 ANAPC5 25368385,22580462 0004,0004 LC ANAPC1 ANAPC5 26344197,12956947,20360068,11076961,12956947,22939629 0401,0096,0676,0401,0004,0401 HT,LC MAGIX ANAPC5 26186194 0004 HT LATS2 ANAPC5 24255178,24255178 0004,1313 HT CFAP97 ANAPC5 26496610,26496610 0007,0004 HT CDC23 ANAPC5 26496610,20360068,26496610,22939629 0007,0676,0004,0401 HT,LC ANAPC7 ANAPC5 20360068,22939629,23160376 0676,0401,0004 LC,HT ANAPC5 ANAPC4 26344197,23078409,25043029,20360068,26083744,25490258,12956947,22939629,12956947 0401,0401,0401,0676,0401,0004,0004,0401,0096 HT,LC ANAPC5 ANAPC2 12956947,12956947,10922056,20360068,22939629 0004,0096,0004,0676,0401 LC,HT ANAPC5 FZR1 12956947,23160376 0096,0004 LC OFD1 ANAPC5 26638075,26638075 1314,1313 HT GRAP2 ANAPC5 26186194 0004 HT TTLL1 ANAPC5 26186194 0004 HT KNG1 ANAPC5 26186194 0004 HT PENK ANAPC5 26186194 0004 HT GTF2E1 ANAPC5 26344197 0401 HT CDC27 ANAPC5 22939629 0401 HT ANAPC15 ANAPC5 26496610,26496610 0007,0004 HT CDC16 ANAPC5 26496610,26344197,26496610,22939629 0007,0401,0004,0401 HT CUL4A ANAPC5 21145461 0004 HT PIFO ANAPC5 26186194 0004 HT ANAPC16 ANAPC5 26344197 0401 HT ANAPC13 ANAPC5 22939629 0401 HT ANAPC1 ANAPC5 26344197,22939629 0401,0401 HT MAGIX ANAPC5 26186194 0004 HT LATS2 ANAPC5 24255178,24255178 0004,1313 HT CFAP97 ANAPC5 26496610,26496610 0007,0004 HT CDC23 ANAPC5 26496610,26496610,22939629 0007,0004,0401 HT ANAPC7 ANAPC5 22939629 0401 HT ANAPC5 ANAPC4 26344197,22939629 0401,0401 HT ANAPC5 ANAPC2 22939629 0401 HT B4DL80 ANAPC5 22792066,16364912,10922056,22193957,15082755,12956947,14657031 0004,0004,0004,0004,0004,0004,0004 LC CDC27 ANAPC5 26811472,20360068,20360068,16364912,10922056,20686030,21241890,25306918,22193957,15082755,27114510,21241890,14657031,12956947,21043528,22792066 0004,0006,0676,0004,0004,0004,0004,0004,0004,0004,0004,0006,0004,0004,0401,0004 LC ANAPC15 ANAPC5 23007861 0004 LC CDC20 ANAPC5 23160376,20360068,12956947,27114510,25306918,26811472 0004,0676,0096,0004,0004,0004 LC CDC16 ANAPC5 20360068 0676 LC MDC1 ANAPC5 22990118,17827148 0004,0004 LC USP37 ANAPC5 26299517,21596315 1313,0004 LC ANAPC16 ANAPC5 20360068,20360068 0676,0006 LC ANAPC13 ANAPC5 20360068 0676 LC Q9BSD8 ANAPC5 25368385,22580462 0004,0004 LC ANAPC1 ANAPC5 12956947,20360068,11076961,12956947 0096,0676,0401,0004 LC CDC23 ANAPC5 20360068 0676 LC ANAPC7 ANAPC5 20360068,23160376 0676,0004 LC ANAPC5 ANAPC4 23078409,25043029,20360068,26083744,25490258,12956947,12956947 0401,0401,0676,0401,0004,0004,0096 LC ANAPC5 ANAPC2 12956947,12956947,10922056,20360068 0004,0096,0004,0676 LC ANAPC5 FZR1 12956947,23160376 0096,0004 LC BACH1 ANAPC5 21988832,21988832 0397,0018 HT PTTG1 ANAPC5 20080579,22193957 0415,0415 LC PABPC1 ANAPC5 15082755,15082755,15082755 0018,0004,0096 LC CCNB1 ANAPC5 20080579,22193957 0415,0415 LC GTF2E1 ANAPC5 26344197 0401 LC CDC27 ANAPC5 21043528,22939629 0401,0401 LC TGFBR1 ANAPC5 15761153 0019 HT ZBTB16 ANAPC5 16169070,16169070 0018,0398 HT CDC16 ANAPC5 26344197,22939629 0401,0401 LC MAPK6 ANAPC5 21900206 0018 HT ANAPC16 ANAPC5 26344197 0401 LC ANAPC13 ANAPC5 22939629 0401 LC ANAPC1 ANAPC5 26344197,11076961,22939629 0401,0401,0401 LC SMURF2 ANAPC5 15761153 0019 HT SMURF1 ANAPC5 15761153 0019 HT CDC23 ANAPC5 22939629 0401 LC ANAPC7 ANAPC5 22939629 0401 LC ANAPC5 ANAPC4 26344197,23078409,25043029,26083744,22939629 0401,0401,0401,0401,0401 LC ANAPC5 ANAPC2 22939629 0401 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9UJX4 Q09472 ANAPC5 EP300 0.21 16319895 Q9UJX4 Q9H4L7 ANAPC5 SMARCAD1 0.126 21549307 Q9UJX4 Q8TCI5 ANAPC5 PIFO 0.126 26186194 Q9UJX4 Q9H211 ANAPC5 CDT1 0.21 18162579 Q9UJX4 Q9H6Y5 ANAPC5 MAGIX 0.126 26186194 Q9UJX4 O75791 ANAPC5 GRAP2 0.126 26186194 Q9UJX4 Q6ZW49 ANAPC5 PAXIP1 0.126 22990118 Q9UJX4 Q6P5F9 ANAPC5 XPO1 0.126 26673895 Q9UJX4 P01042 ANAPC5 KNG1 0.126 26186194 Q9UJX4 Q8BTZ4 ANAPC5 ANAPC5 0.126 20360068 Q9UJX4 P01210 ANAPC5 PENK 0.126 26186194 Q9UJX4 O95922 ANAPC5 TTLL1 0.126 26186194 Q9Z1B5 Q9UJX4 MAD2L1 ANAPC5 0.236 20360068 Q9UJX4 Q9P2B7 ANAPC5 KIAA1430 0.236 26496610 Q9Z1S0 Q9UJX4 BUB1B ANAPC5 0.236 20360068 Q9UJX4 Q9NRM7 ANAPC5 LATS2 0.236 24255178 Q9UJX4 O43684 ANAPC5 BUB3 0.236 20360068 Q9UJX4 O14867 ANAPC5 BACH1 0.286 21988832 Q9UJX4 Q13042 ANAPC5 CDC16 0.569 20360068,26344197,26496610,22939629 Q9UJX4 Q12834 ANAPC5 CDC20 0.74 25306918,26811472,20360068,27114510,23160376 Q9UJX6 Q9UJX4 ANAPC2 ANAPC5 0.576 10922056,20360068,12956947,22939629 Q9UKT4 Q9UJX4 FBXO5 ANAPC5 0.454 16921029 Q9UM11 Q9UJX4 FZR1 ANAPC5 0.354 23160376,12956947 Q9UJX4 Q92793 ANAPC5 CREBBP 0.454 16319895 Q9UJX4 Q96DE5 ANAPC5 ANAPC16 0.531 20360068,26344197 Q9UJX4 Q16659 ANAPC5 MAPK6 0.332 21900206 Q9UJX4 Q9BS18 ANAPC5 ANAPC13 0.236 20360068 Q9UJX4 Q14676 ANAPC5 MDC1 0.309 22990118,17827148 Q9UJX4 Q7TSJ6 ANAPC5 LATS2 0.196 24255178 Q9UJX4 Q86T82 ANAPC5 USP37 0.309 26299517,21596315 Q9UJX4 O55234 ANAPC5 PSMB5 0.236 26496610 Q9UJX4 O75665 ANAPC5 OFD1 0.236 26638075 Q9UJX4 P60006 ANAPC5 ANAPC15 0.396 26496610,23007861 Q9UJX4 P60484 ANAPC5 PTEN 0.507 21241890 Q9UJX4 Q8BZQ7 ANAPC5 ANAPC2 0.332 26496610,20360068 Q9UJX4 Q8R034 ANAPC5 ANAPC13 0.332 26496610,20360068 Q9UJX4 Q9UJX2 ANAPC5 CDC23 0.531 22939629,20360068,26496610 Q9UJX4 P11940 ANAPC5 PABPC1 0.623 15082755 Q9UJX4 Q9H1A4 ANAPC5 ANAPC1 0.61 20360068,26344197,11076961,12956947,22939629 Q9UJX5 Q9UJX4 ANAPC4 ANAPC5 0.808 12956947,22939629,23078409,25043029,25490258,20360068,26344197,26083744 Q9UJX4 Q99JP4 ANAPC5 CDC26 0.332 26496610,20360068 Q9UJX4 Q9CPV2 ANAPC5 ANAPC16 0.416 26496610,20360068 Q9UJX4 Q9JJ66 ANAPC5 CDC20 0.416 26496610,20360068 Q9UJX4 Q8BGZ4 ANAPC5 CDC23 0.416 26496610,20360068 Q9UJX4 Q8R349 ANAPC5 CDC16 0.416 26496610,20360068 Q9UJX4 P30260 ANAPC5 CDC27 0.972 21043528,10922056,22193957,20360068,27114510,15082755,25306918,16364912,21241890,26811472,20686030,12956947,22939629,22792066 Q9UJX4 Q92731 ANAPC5 ESR2 0.126 21182203 Q9UJX4 Q96B97 ANAPC5 SH3KBP1 0.126 19531213 Q9UJX4 P29083 ANAPC5 GTF2E1 0.081 26344197 Q9UJX4 Q9P2P5 ANAPC5 HECW2 0.126 24163370 Q9UJX4 Q9UJX3 ANAPC5 ANAPC7 0.445 22939629,23160376,20360068 Q9UJX4 O60566 ANAPC5 BUB1B 0.236 20360068 Q9UJX4 Q01094 ANAPC5 E2F1 0.376 22580462,25368385 Q9UJX4 Q05516 ANAPC5 ZBTB16 0.286 16169070 Q9UJX4 Q8NHZ8 ANAPC5 CDC26 0.332 20360068 Q9UPN9 Q9UJX4 TRIM33 ANAPC5 0.376 23160376 Q9UPP1 Q9UJX4 PHF8 ANAPC5 0.21 23979597 Q9UJX4 P46531 ANAPC5 NOTCH1 0.126 23022380 Q9UJX4 Q13619 ANAPC5 CUL4A 0.126 21145461 Q9UJX4 P48431 ANAPC5 SOX2 0.126 23667531 Q9UJX4 Q12888 ANAPC5 TP53BP1 0.126 22990118 Q9UJX4 P53995 ANAPC5 ANAPC1 0.126 20360068 Q9UJX4 Q16763 ANAPC5 UBE2S 0.309 25306923 Q9UJX4 A0JLT2 ANAPC5 MED19 0.126 15175163

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 MED19 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database UBE2C ANAPC5 MI:0362 inference MI:1106 pathways database BACH1 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database AURKA ANAPC5 MI:0362 inference MI:1106 pathways database XPO1 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database BUB3 ANAPC5 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database BUB1B ANAPC5 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database OFD1 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database GRAP2 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database TTLL1 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database APC2 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database PTTG1 ANAPC5 MI:0362 inference MI:1106 pathways database ABL1 ANAPC5 MI:0362 inference MI:0461 interaction database KNG1 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database PENK ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database CDK1 ANAPC5 MI:0362 inference MI:1106 pathways database UBB ANAPC5 MI:0362 inference MI:1106 pathways database UBC ANAPC5 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database PABPC1 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database CDH1 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database CCNB1 ANAPC5 MI:0362 inference MI:1106 pathways database CDK2 ANAPC5 MI:0362 inference MI:1106 pathways database PSMB5 ANAPC5 MI:0362 inference MI:0461 interaction database CDC27 ANAPC5 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database CTNNB1 ANAPC5 MI:0362 inference MI:0461 interaction database TGFBR1 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database NOTCH1 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database SOX2 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D1 ANAPC5 MI:0362 inference MI:1106 pathways database NEK2 ANAPC5 MI:0362 inference MI:1106 pathways database UBE2E1 ANAPC5 MI:0362 inference MI:1106 pathways database PLK1 ANAPC5 MI:0362 inference MI:1106 pathways database ANAPC15 ANAPC5 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database PTEN ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database RPS27A ANAPC5 MI:0362 inference MI:1106 pathways database UBA52 ANAPC5 MI:0362 inference MI:1106 pathways database E2F1 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database ZBTB16 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database EP300 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database CDC20 ANAPC5 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database TP53BP1 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database CDC16 ANAPC5 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database CHAF1A ANAPC5 MI:0362 inference MI:0461 interaction database MAD2L1 ANAPC5 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database SKP2 ANAPC5 MI:0362 inference MI:1106 pathways database CUL4A ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database TFDP1 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database MDC1 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database NEDD8 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database MAPK6 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database UBE2S ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database FIP1L1 ANAPC5 MI:0362 inference MI:0461 interaction database PAXIP1 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database USP37 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database CDC26 ANAPC5 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database PIFO ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database ESR2 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database CREBBP ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database SH3KBP1 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database ANAPC16 ANAPC5 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database AURKB ANAPC5 MI:0362 inference MI:1106 pathways database EHMT2 ANAPC5 MI:0362 inference MI:1106 pathways database MAP3K3 ANAPC5 MI:0362 inference MI:0461 interaction database ANAPC13 ANAPC5 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database WDR33 ANAPC5 MI:0362 inference MI:0461 interaction database ANAPC1 ANAPC5 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database CDT1 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database SMARCAD1 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database MAGIX ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database EHMT1 ANAPC5 MI:0362 inference MI:1106 pathways database SMURF2 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database SMURF1 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database LATS2 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database ANAPC11 ANAPC5 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database CFAP97 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database HECW2 ANAPC5 MI:0045 experimental interaction detection MI:0461 interaction database CDC23 ANAPC5 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ANAPC7 ANAPC5 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ANAPC5 ANAPC4 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ANAPC5 ANAPC2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ANAPC5 FBXO5 MI:0045 experimental interaction detection MI:0461 interaction database ANAPC5 FZR1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ANAPC5 ANAPC10 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database ANAPC5 TRIM33 MI:0045 experimental interaction detection MI:0461 interaction database ANAPC5 PHF8 MI:0045 experimental interaction detection MI:0461 interaction database