Disease associated variation - ClinVar Allele ID Type Name RS#dbSNP Phenotype IDs Chromosome Start Stop Reference Alternate 76321 single nucleotide variant NM_006044.3(HDAC6):c.*282A>T 398122390 Gene:100820762,MedGen:C3275476,OMIM:300863,Orphanet:ORPHA163966 X 48683304 48683304 A T 76321 single nucleotide variant NM_006044.3(HDAC6):c.*282A>T 398122390 Gene:100820762,MedGen:C3275476,OMIM:300863,Orphanet:ORPHA163966 X 48824894 48824894 A T 205525 single nucleotide variant NM_006044.3(HDAC6):c.1538G>A (p.Arg513His) 782506012 Human Phenotype Ontology:HP:0002269,MedGen:CN002060 X 48674592 48674592 G A 205525 single nucleotide variant NM_006044.3(HDAC6):c.1538G>A (p.Arg513His) 782506012 Human Phenotype Ontology:HP:0002269,MedGen:CN002060 X 48816185 48816185 G A

Disease associated variation - GWAS Central Study Name Source Marker Accession Chromosome Marker Start Marker Stop Alleles Gene Section P-value -log(p-value) GWAS of prostate cancer rs2075840 X 48672788 48672788 intronic 0.280168 0.55258147011039

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000094631.18 HDAC6 300272