Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change BLCA 22 21272283 21272283 + Missense_Mutation SNP C C T TCGA-KQ-A41R-01A-21D-A34U-08 TCGA-KQ-A41R-10G-01D-A34X-08 g.chr22:21272283C>T c.61C>T c.(61-63)Cgc>Tgc p.R21C BLCA 22 21272303 21272303 + Silent SNP G G A TCGA-DK-A2I4-01A-11D-A21A-08 TCGA-DK-A2I4-10A-01D-A21A-08 g.chr22:21272303G>A c.81G>A c.(79-81)cgG>cgA p.R27R BRCA 22 21272296 21272296 + Missense_Mutation SNP A A G TCGA-C8-A130-01A-31D-A10Y-09 TCGA-C8-A130-10A-01D-A110-09 g.chr22:21272296A>G c.74A>G c.(73-75)cAg>cGg p.Q25R CHOL 22 21304043 21304043 + Missense_Mutation SNP G G T TCGA-W5-AA2G-01A-11D-A417-09 TCGA-W5-AA2G-10A-01D-A41A-09 g.chr22:21304043G>T c.822G>T c.(820-822)caG>caT p.Q274H COAD 22 21272358 21272358 + Missense_Mutation SNP G G T TCGA-G4-6628-01A-11D-1835-10 TCGA-G4-6628-10A-01D-1835-10 g.chr22:21272358G>T c.136G>T c.(136-138)Ggg>Tgg p.G46W COAD 22 21288098 21288098 + Missense_Mutation SNP G G A TCGA-G4-6304-01A-11D-1924-10 TCGA-G4-6304-10A-01D-1924-10 g.chr22:21288098G>A c.343G>A c.(343-345)Gca>Aca p.A115T COAD 22 21288189 21288189 + Missense_Mutation SNP A A C TCGA-AA-A00N-01A-02W-A00E-09 TCGA-AA-A00N-10A-01W-A00E-09 g.chr22:21288189A>C c.434A>C c.(433-435)aAa>aCa p.K145T COAD 22 21288369 21288369 + Missense_Mutation SNP A A G TCGA-AA-3492-01A-01D-1408-10 TCGA-AA-3492-11A-01D-1408-10 g.chr22:21288369A>G c.614A>G c.(613-615)cAt>cGt p.H205R COAD 22 21304066 21304066 + Missense_Mutation SNP G G A TCGA-AA-3877-01A-01W-0995-10 TCGA-AA-3877-10A-01W-0995-10 g.chr22:21304066G>A c.845G>A c.(844-846)cGc>cAc p.R282H COADREAD 22 21272358 21272358 + Missense_Mutation SNP G G T TCGA-G4-6628-01A-11D-1835-10 TCGA-G4-6628-10A-01D-1835-10 g.chr22:21272358G>T c.136G>T c.(136-138)Ggg>Tgg p.G46W COADREAD 22 21288098 21288098 + Missense_Mutation SNP G G A TCGA-G4-6304-01A-11D-1924-10 TCGA-G4-6304-10A-01D-1924-10 g.chr22:21288098G>A c.343G>A c.(343-345)Gca>Aca p.A115T COADREAD 22 21288189 21288189 + Missense_Mutation SNP A A C TCGA-AA-A00N-01A-02W-A00E-09 TCGA-AA-A00N-10A-01W-A00E-09 g.chr22:21288189A>C c.434A>C c.(433-435)aAa>aCa p.K145T COADREAD 22 21288369 21288369 + Missense_Mutation SNP A A G TCGA-AA-3492-01A-01D-1408-10 TCGA-AA-3492-11A-01D-1408-10 g.chr22:21288369A>G c.614A>G c.(613-615)cAt>cGt p.H205R COADREAD 22 21288475 21288475 + Silent SNP G G A TCGA-AG-A002-01A-01W-A00K-09 TCGA-AG-A002-10A-01W-A00K-09 g.chr22:21288475G>A c.720G>A c.(718-720)gcG>gcA p.A240A COADREAD 22 21304066 21304066 + Missense_Mutation SNP G G A TCGA-AA-3877-01A-01W-0995-10 TCGA-AA-3877-10A-01W-0995-10 g.chr22:21304066G>A c.845G>A c.(844-846)cGc>cAc p.R282H DLBC 22 21272249 21272249 + Silent SNP G G A TCGA-G8-6325-01A-11D-2210-10 TCGA-G8-6325-10A-01D-2210-10 g.chr22:21272249G>A c.27G>A c.(25-27)tcG>tcA p.S9S ESCA 22 21272499 21272499 + Silent SNP C C T TCGA-LN-A4A6-01A-11D-A27G-09 TCGA-LN-A4A6-10A-01D-A27G-09 g.chr22:21272499C>T c.277C>T c.(277-279)Ctg>Ttg p.L93L GBM 22 21272527 21272527 + Missense_Mutation SNP C C T TCGA-32-2638-01A-01D-1495-08 TCGA-32-2638-10A-01D-1495-08 g.chr22:21272527C>T c.305C>T c.(304-306)gCg>gTg p.A102V GBMLGG 22 21272527 21272527 + Missense_Mutation SNP C C T TCGA-32-2638-01A-01D-1495-08 TCGA-32-2638-10A-01D-1495-08 g.chr22:21272527C>T c.305C>T c.(304-306)gCg>gTg p.A102V GBMLGG 22 21288371 21288371 + Missense_Mutation SNP G G A TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr22:21288371G>A c.616G>A c.(616-618)Gca>Aca p.A206T GBMLGG 22 21304088 21304088 + Silent SNP G G A TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr22:21304088G>A c.867G>A c.(865-867)acG>acA p.T289T HNSC 22 21272519 21272519 + Missense_Mutation SNP C C G TCGA-CV-A6JE-01A-11D-A31L-08 TCGA-CV-A6JE-10A-01D-A31J-08 g.chr22:21272519C>G c.297C>G c.(295-297)atC>atG p.I99M HNSC 22 21304053 21304053 + Missense_Mutation SNP G G A TCGA-CV-5444-01A-02D-1512-08 TCGA-CV-5444-11A-01D-1512-08 g.chr22:21304053G>A c.832G>A c.(832-834)Gaa>Aaa p.E278K HNSC 22 21304075 21304075 + Frame_Shift_Del DEL T T - TCGA-IQ-A61H-01A-11D-A30E-08 TCGA-IQ-A61H-10A-01D-A30H-08 g.chr22:21304075delT c.854delT c.(853-855)cttfs p.L285fs LGG 22 21288371 21288371 + Missense_Mutation SNP G G A TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr22:21288371G>A c.616G>A c.(616-618)Gca>Aca p.A206T LGG 22 21304088 21304088 + Silent SNP G G A TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr22:21304088G>A c.867G>A c.(865-867)acG>acA p.T289T LUAD 22 21272460 21272460 + Missense_Mutation SNP C C G TCGA-69-A59K-01A-11D-A25L-08 TCGA-69-A59K-10A-01D-A25L-08 g.chr22:21272460C>G c.238C>G c.(238-240)Cat>Gat p.H80D LUAD 22 21288146 21288146 + Missense_Mutation SNP C C G TCGA-49-4486-01A-01D-1265-08 TCGA-49-4486-11A-01D-1265-08 g.chr22:21288146C>G c.391C>G c.(391-393)Ctg>Gtg p.L131V LUAD 22 21288246 21288246 + Missense_Mutation SNP G G A TCGA-55-8203-01A-11D-2238-08 TCGA-55-8203-10A-01D-2238-08 g.chr22:21288246G>A c.491G>A c.(490-492)cGg>cAg p.R164Q LUAD 22 21288427 21288427 + Silent SNP G G T TCGA-86-8673-01A-11D-2393-08 TCGA-86-8673-10A-01D-2393-08 g.chr22:21288427G>T c.672G>T c.(670-672)ggG>ggT p.G224G LUAD 22 21288428 21288428 + Missense_Mutation SNP G G T TCGA-86-8673-01A-11D-2393-08 TCGA-86-8673-10A-01D-2393-08 g.chr22:21288428G>T c.673G>T c.(673-675)Gca>Tca p.A225S LUSC 22 21288203 21288203 + Silent SNP C C T TCGA-85-6561-01A-11D-1817-08 TCGA-85-6561-10A-01D-1817-08 g.chr22:21288203C>T c.448C>T c.(448-450)Cta>Tta p.L150L LUSC 22 21288386 21288386 + Missense_Mutation SNP C C G TCGA-63-5131-01A-01D-1441-08 TCGA-63-5131-10A-01D-1441-08 g.chr22:21288386C>G c.631C>G c.(631-633)Cag>Gag p.Q211E LUSC 22 21288526 21288526 + Silent SNP A A C TCGA-46-3769-01A-01D-0983-08 TCGA-46-3769-10A-01D-0983-08 g.chr22:21288526A>C c.771A>C c.(769-771)gcA>gcC p.A257A PAAD 22 21288172 21288172 + Silent SNP C C A TCGA-2J-AAB8-01A-12D-A40W-08 TCGA-2J-AAB8-10A-01D-A40W-08 g.chr22:21288172C>A c.417C>A c.(415-417)gcC>gcA p.A139A READ 22 21288475 21288475 + Silent SNP G G A TCGA-AG-A002-01A-01W-A00K-09 TCGA-AG-A002-10A-01W-A00K-09 g.chr22:21288475G>A c.720G>A c.(718-720)gcG>gcA p.A240A SKCM 22 21288222 21288222 + Missense_Mutation SNP C C T TCGA-ER-A198-06A-11D-A196-08 TCGA-ER-A198-10A-01D-A198-08 g.chr22:21288222C>T c.467C>T c.(466-468)cCt>cTt p.P156L SKCM 22 21304075 21304075 + Frame_Shift_Del DEL T T - TCGA-D3-A1Q3-06A-11D-A196-08 TCGA-D3-A1Q3-10A-01D-A198-08 g.chr22:21304075delT c.854delT c.(853-855)cttfs p.L285fs

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-CN 22 21272248 21272248 single base substitution C T exon_variant BLCA-CN 22 21272248 21272248 single base substitution C T missense_variant S9L 26C>T BLCA-CN 22 21288096 21288096 single base substitution C T exon_variant BLCA-CN 22 21288096 21288096 single base substitution C T missense_variant S114L 341C>T BLCA-US 22 21272303 21272303 single base substitution G A exon_variant BLCA-US 22 21272303 21272303 single base substitution G A synonymous_variant R27R 81G>A BRCA-EU 22 21266734 21266734 single base substitution C G upstream_gene_variant BRCA-EU 22 21268563 21268563 single base substitution A G upstream_gene_variant BRCA-EU 22 21269038 21269038 single base substitution G A upstream_gene_variant BRCA-EU 22 21271532 21271532 single base substitution G A upstream_gene_variant BRCA-EU 22 21272382 21272382 single base substitution G A exon_variant BRCA-EU 22 21272382 21272382 single base substitution G A missense_variant E54K 160G>A BRCA-EU 22 21273134 21273134 single base substitution T G intron_variant BRCA-EU 22 21274046 21274046 single base substitution C T intron_variant BRCA-EU 22 21274340 21274340 single base substitution G C intron_variant BRCA-EU 22 21274680 21274680 single base substitution C T intron_variant BRCA-EU 22 21274682 21274682 single base substitution C T intron_variant BRCA-EU 22 21275702 21275702 single base substitution G A intron_variant BRCA-EU 22 21276659 21276659 single base substitution A C intron_variant BRCA-EU 22 21277664 21277664 single base substitution A G intron_variant BRCA-EU 22 21277735 21277735 single base substitution T C intron_variant BRCA-EU 22 21277800 21277800 single base substitution C T intron_variant BRCA-EU 22 21280024 21280024 single base substitution A G intron_variant BRCA-EU 22 21280574 21280574 single base substitution G T intron_variant BRCA-EU 22 21281599 21281599 single base substitution C T intron_variant BRCA-EU 22 21281803 21281803 single base substitution T G intron_variant BRCA-EU 22 21283214 21283214 single base substitution A G intron_variant BRCA-EU 22 21283644 21283644 single base substitution G T intron_variant BRCA-EU 22 21283901 21283901 single base substitution G A intron_variant BRCA-EU 22 21284001 21284001 single base substitution G A intron_variant BRCA-EU 22 21285676 21285676 single base substitution G A intron_variant BRCA-EU 22 21288172 21288172 single base substitution C G exon_variant BRCA-EU 22 21288172 21288172 single base substitution C G synonymous_variant A139A 417C>G BRCA-EU 22 21289179 21289179 single base substitution G C intron_variant BRCA-EU 22 21291532 21291532 single base substitution G C intron_variant BRCA-EU 22 21291669 21291669 single base substitution C T intron_variant BRCA-EU 22 21292549 21292549 single base substitution C G intron_variant BRCA-EU 22 21294465 21294465 single base substitution A G intron_variant BRCA-EU 22 21297247 21297247 single base substitution C A intron_variant BRCA-EU 22 21297296 21297296 deletion of <=200bp A - intron_variant BRCA-EU 22 21297562 21297562 single base substitution C T intron_variant BRCA-EU 22 21299647 21299647 single base substitution C T intron_variant BRCA-EU 22 21303288 21303288 single base substitution G C intron_variant BRCA-EU 22 21304874 21304874 single base substitution T C 3_prime_UTR_variant BRCA-EU 22 21304874 21304874 single base substitution T C intron_variant BRCA-EU 22 21305076 21305076 single base substitution T C 3_prime_UTR_variant BRCA-EU 22 21305076 21305076 single base substitution T C intron_variant BRCA-EU 22 21305547 21305547 single base substitution A G 3_prime_UTR_variant BRCA-EU 22 21305547 21305547 single base substitution A G intron_variant BRCA-EU 22 21305686 21305686 single base substitution G A 3_prime_UTR_variant BRCA-EU 22 21305686 21305686 single base substitution G A intron_variant BRCA-EU 22 21305716 21305716 single base substitution G C 3_prime_UTR_variant BRCA-EU 22 21305716 21305716 single base substitution G C intron_variant BRCA-EU 22 21306764 21306764 single base substitution T G 3_prime_UTR_variant BRCA-EU 22 21306764 21306764 single base substitution T G intron_variant BRCA-EU 22 21308405 21308405 single base substitution C T downstream_gene_variant BRCA-EU 22 21308470 21308470 single base substitution G C downstream_gene_variant BRCA-EU 22 21308648 21308648 single base substitution C T downstream_gene_variant BRCA-EU 22 21309983 21309983 single base substitution G A downstream_gene_variant BRCA-EU 22 21310153 21310153 single base substitution T C downstream_gene_variant BRCA-EU 22 21312009 21312009 single base substitution C T downstream_gene_variant BRCA-EU 22 21312403 21312403 single base substitution G A downstream_gene_variant BRCA-FR 22 21266734 21266734 single base substitution C G upstream_gene_variant BRCA-FR 22 21269038 21269038 single base substitution G A upstream_gene_variant BRCA-FR 22 21271307 21271307 single base substitution C T upstream_gene_variant BRCA-FR 22 21271532 21271532 single base substitution G A upstream_gene_variant BRCA-FR 22 21272382 21272382 single base substitution G A exon_variant BRCA-FR 22 21272382 21272382 single base substitution G A missense_variant E54K 160G>A BRCA-FR 22 21274046 21274046 single base substitution C T intron_variant BRCA-FR 22 21274680 21274680 single base substitution C T intron_variant BRCA-FR 22 21274682 21274682 single base substitution C T intron_variant BRCA-FR 22 21277664 21277664 single base substitution A G intron_variant BRCA-FR 22 21288814 21288814 single base substitution A G intron_variant BRCA-FR 22 21303288 21303288 single base substitution G C intron_variant BRCA-FR 22 21308648 21308648 single base substitution C T downstream_gene_variant BRCA-FR 22 21312009 21312009 single base substitution C T downstream_gene_variant BRCA-UK 22 21275702 21275702 single base substitution G A intron_variant BRCA-UK 22 21289179 21289179 single base substitution G C intron_variant BRCA-UK 22 21312217 21312217 single base substitution C G downstream_gene_variant BRCA-US 22 21272296 21272296 single base substitution A G exon_variant BRCA-US 22 21272296 21272296 single base substitution A G missense_variant Q25R 74A>G CLLE-ES 22 21275672 21275672 single base substitution A T intron_variant CLLE-ES 22 21279369 21279369 single base substitution C T intron_variant CLLE-ES 22 21308321 21308321 single base substitution C A downstream_gene_variant COAD-US 22 21272358 21272358 single base substitution G T exon_variant COAD-US 22 21272358 21272358 single base substitution G T missense_variant G46W 136G>T COAD-US 22 21288369 21288369 single base substitution A G exon_variant COAD-US 22 21288369 21288369 single base substitution A G missense_variant H205R 614A>G COCA-CN 22 21311531 21311531 single base substitution C T downstream_gene_variant ESAD-UK 22 21269721 21269721 single base substitution G C upstream_gene_variant ESAD-UK 22 21270937 21270939 deletion of <=200bp AAG - upstream_gene_variant ESAD-UK 22 21272750 21272750 single base substitution C T intron_variant ESAD-UK 22 21275075 21275075 single base substitution C T intron_variant ESAD-UK 22 21276445 21276445 single base substitution G A intron_variant ESAD-UK 22 21277970 21277970 single base substitution C T intron_variant ESAD-UK 22 21280381 21280381 single base substitution A T intron_variant ESAD-UK 22 21281873 21281873 single base substitution G A intron_variant ESAD-UK 22 21281991 21281991 single base substitution C T intron_variant ESAD-UK 22 21282774 21282774 single base substitution A C intron_variant ESAD-UK 22 21283649 21283649 single base substitution T G intron_variant ESAD-UK 22 21284222 21284222 single base substitution C G intron_variant ESAD-UK 22 21284921 21284921 single base substitution C T intron_variant ESAD-UK 22 21285694 21285694 single base substitution C G intron_variant ESAD-UK 22 21287219 21287219 single base substitution T G intron_variant ESAD-UK 22 21293231 21293231 single base substitution C T intron_variant ESAD-UK 22 21298341 21298341 deletion of <=200bp G - intron_variant ESAD-UK 22 21301001 21301001 insertion of <=200bp - C intron_variant ESAD-UK 22 21301021 21301021 single base substitution A C intron_variant ESAD-UK 22 21302990 21302990 single base substitution G A intron_variant ESAD-UK 22 21306886 21306886 single base substitution C T 3_prime_UTR_variant ESAD-UK 22 21306886 21306886 single base substitution C T intron_variant ESAD-UK 22 21311502 21311502 single base substitution C G downstream_gene_variant ESCA-CN 22 21272413 21272413 single base substitution A T exon_variant ESCA-CN 22 21272413 21272413 single base substitution A T missense_variant N64I 191A>T GBM-US 22 21272527 21272527 single base substitution C T exon_variant GBM-US 22 21272527 21272527 single base substitution C T missense_variant A102V 305C>T KIRP-US 22 21272259 21272259 single base substitution G C exon_variant KIRP-US 22 21272259 21272259 single base substitution G C missense_variant A13P 37G>C LAML-KR 22 21276076 21276076 single base substitution A C intron_variant LAML-KR 22 21276100 21276100 single base substitution C T intron_variant LAML-KR 22 21279234 21279234 single base substitution G T intron_variant LAML-KR 22 21289998 21289998 single base substitution G T intron_variant LAML-KR 22 21293535 21293535 single base substitution T C intron_variant LICA-FR 22 21269297 21269297 single base substitution T A upstream_gene_variant LICA-FR 22 21272404 21272416 deletion of <=200bp ACATCATCAACTC - exon_variant LICA-FR 22 21272404 21272416 deletion of <=200bp ACATCATCAACTC - frameshift_variant YIINS61 LICA-FR 22 21298449 21298449 single base substitution A T intron_variant LICA-FR 22 21301965 21301967 deletion of <=200bp TTT - intron_variant LINC-JP 22 21272730 21272730 single base substitution T C intron_variant LINC-JP 22 21275223 21275229 deletion of <=200bp CATTTTC - intron_variant LINC-JP 22 21283951 21283951 single base substitution A G intron_variant LINC-JP 22 21293158 21293158 single base substitution A G intron_variant LINC-JP 22 21295168 21295168 single base substitution A G intron_variant LINC-JP 22 21298454 21298454 single base substitution C T intron_variant LINC-JP 22 21304627 21304627 single base substitution C T 3_prime_UTR_variant LINC-JP 22 21304627 21304627 single base substitution C T intron_variant LIRI-JP 22 21269271 21269271 single base substitution A G upstream_gene_variant LIRI-JP 22 21271929 21271929 single base substitution G T 5_prime_UTR_variant LIRI-JP 22 21277350 21277350 single base substitution C A intron_variant LIRI-JP 22 21278415 21278415 single base substitution A T intron_variant LIRI-JP 22 21278588 21278588 single base substitution A G intron_variant LIRI-JP 22 21280168 21280168 single base substitution A G intron_variant LIRI-JP 22 21283218 21283218 single base substitution A T intron_variant LIRI-JP 22 21283359 21283359 single base substitution T G intron_variant LIRI-JP 22 21284429 21284429 single base substitution T A intron_variant LIRI-JP 22 21284817 21284817 single base substitution G A intron_variant LIRI-JP 22 21285668 21285668 single base substitution G A intron_variant LIRI-JP 22 21288220 21288220 single base substitution G A exon_variant LIRI-JP 22 21288220 21288220 single base substitution G A synonymous_variant K155K 465G>A LIRI-JP 22 21291298 21291298 single base substitution G A intron_variant LIRI-JP 22 21291967 21291967 single base substitution T A intron_variant LIRI-JP 22 21291971 21291971 single base substitution C G intron_variant LIRI-JP 22 21291972 21291972 single base substitution C T intron_variant LIRI-JP 22 21292966 21292966 single base substitution A G intron_variant LIRI-JP 22 21293468 21293468 single base substitution G A intron_variant LIRI-JP 22 21293814 21293814 single base substitution G A intron_variant LIRI-JP 22 21298068 21298068 single base substitution C T intron_variant LIRI-JP 22 21299745 21299745 single base substitution C T intron_variant LIRI-JP 22 21300040 21300040 single base substitution G A intron_variant LIRI-JP 22 21300240 21300240 single base substitution G A intron_variant LIRI-JP 22 21300380 21300380 single base substitution G T intron_variant LIRI-JP 22 21300418 21300418 single base substitution A T intron_variant LIRI-JP 22 21300975 21300975 single base substitution A G intron_variant LIRI-JP 22 21306958 21306980 deletion of <=200bp GCTCTGCTCTACCATGTTTAAAG - 3_prime_UTR_variant LIRI-JP 22 21306958 21306980 deletion of <=200bp GCTCTGCTCTACCATGTTTAAAG - intron_variant LIRI-JP 22 21307416 21307416 single base substitution G C 3_prime_UTR_variant LIRI-JP 22 21307416 21307416 single base substitution G C intron_variant LIRI-JP 22 21309300 21309300 single base substitution G A downstream_gene_variant LIRI-JP 22 21309842 21309842 single base substitution T G downstream_gene_variant LIRI-JP 22 21311264 21311264 single base substitution G A downstream_gene_variant LUSC-KR 22 21271215 21271215 single base substitution C A upstream_gene_variant LUSC-KR 22 21277854 21277854 single base substitution C T intron_variant LUSC-KR 22 21282511 21282511 single base substitution G A intron_variant LUSC-KR 22 21291532 21291532 single base substitution G T intron_variant LUSC-KR 22 21299320 21299320 single base substitution C T intron_variant LUSC-KR 22 21299603 21299603 single base substitution C T intron_variant LUSC-KR 22 21303460 21303460 single base substitution C G intron_variant LUSC-US 22 21288203 21288203 single base substitution C T exon_variant LUSC-US 22 21288203 21288203 single base substitution C T synonymous_variant L150L 448C>T LUSC-US 22 21288386 21288386 single base substitution C G exon_variant LUSC-US 22 21288386 21288386 single base substitution C G missense_variant Q211E 631C>G LUSC-US 22 21288526 21288526 single base substitution A C exon_variant LUSC-US 22 21288526 21288526 single base substitution A C synonymous_variant A257A 771A>C MALY-DE 22 21270371 21270371 single base substitution C A upstream_gene_variant MALY-DE 22 21274300 21274300 single base substitution T A intron_variant MALY-DE 22 21275250 21275250 single base substitution T G intron_variant MALY-DE 22 21275804 21275804 insertion of <=200bp - ACAGGAGGGACCTGTATA intron_variant MALY-DE 22 21278799 21278799 single base substitution C T intron_variant MALY-DE 22 21283037 21283037 single base substitution G A intron_variant MALY-DE 22 21284493 21284493 single base substitution A G intron_variant MALY-DE 22 21288578 21288578 single base substitution T C intron_variant MALY-DE 22 21290071 21290071 single base substitution G A intron_variant MALY-DE 22 21290976 21290976 single base substitution G T intron_variant MALY-DE 22 21303399 21303400 deletion of <=200bp TG - intron_variant MALY-DE 22 21308161 21308161 single base substitution C T downstream_gene_variant MALY-DE 22 21309737 21309737 single base substitution T G downstream_gene_variant MELA-AU 22 21266771 21266771 single base substitution C T upstream_gene_variant MELA-AU 22 21266803 21266803 single base substitution T A upstream_gene_variant MELA-AU 22 21267106 21267106 single base substitution A G upstream_gene_variant MELA-AU 22 21267251 21267252 multiple base substitution (>=2bp and <=200bp) GG AA upstream_gene_variant MELA-AU 22 21267500 21267500 single base substitution C T upstream_gene_variant MELA-AU 22 21267593 21267593 single base substitution C T upstream_gene_variant MELA-AU 22 21267604 21267604 single base substitution G A upstream_gene_variant MELA-AU 22 21268129 21268129 single base substitution G A upstream_gene_variant MELA-AU 22 21268362 21268362 single base substitution G A upstream_gene_variant MELA-AU 22 21268488 21268488 single base substitution C T upstream_gene_variant MELA-AU 22 21269110 21269110 single base substitution G A upstream_gene_variant MELA-AU 22 21269302 21269302 single base substitution G A upstream_gene_variant MELA-AU 22 21270019 21270019 single base substitution G A upstream_gene_variant MELA-AU 22 21270044 21270044 single base substitution C T upstream_gene_variant MELA-AU 22 21270439 21270439 single base substitution G A upstream_gene_variant MELA-AU 22 21270899 21270899 single base substitution G A upstream_gene_variant MELA-AU 22 21272136 21272136 deletion of <=200bp C - 5_prime_UTR_variant MELA-AU 22 21272826 21272826 single base substitution A G intron_variant MELA-AU 22 21272853 21272853 single base substitution G A intron_variant MELA-AU 22 21273576 21273576 single base substitution C T intron_variant MELA-AU 22 21274890 21274890 single base substitution T C intron_variant MELA-AU 22 21275085 21275085 single base substitution C T intron_variant MELA-AU 22 21275333 21275333 single base substitution C T intron_variant MELA-AU 22 21275436 21275436 single base substitution A G intron_variant MELA-AU 22 21276335 21276335 single base substitution T G intron_variant MELA-AU 22 21276410 21276410 single base substitution C T intron_variant MELA-AU 22 21276835 21276835 single base substitution G A intron_variant MELA-AU 22 21277186 21277186 single base substitution C A intron_variant MELA-AU 22 21277959 21277959 single base substitution T C intron_variant MELA-AU 22 21278262 21278262 single base substitution C T intron_variant MELA-AU 22 21278632 21278632 single base substitution C T intron_variant MELA-AU 22 21279504 21279504 single base substitution C T intron_variant MELA-AU 22 21279580 21279580 single base substitution C G intron_variant MELA-AU 22 21279804 21279804 single base substitution G A intron_variant MELA-AU 22 21279936 21279936 single base substitution G A intron_variant MELA-AU 22 21280098 21280098 single base substitution T A intron_variant MELA-AU 22 21280476 21280476 single base substitution G A intron_variant MELA-AU 22 21280773 21280773 single base substitution G T intron_variant MELA-AU 22 21281383 21281383 single base substitution G A intron_variant MELA-AU 22 21281393 21281393 single base substitution C T intron_variant MELA-AU 22 21282815 21282815 single base substitution A G intron_variant MELA-AU 22 21283228 21283228 single base substitution G A intron_variant MELA-AU 22 21283688 21283688 single base substitution C T intron_variant MELA-AU 22 21283831 21283831 single base substitution A C intron_variant MELA-AU 22 21284083 21284083 single base substitution G A intron_variant MELA-AU 22 21284347 21284347 single base substitution T A intron_variant MELA-AU 22 21288836 21288836 single base substitution T C intron_variant MELA-AU 22 21289297 21289297 single base substitution T C intron_variant MELA-AU 22 21290070 21290070 single base substitution C T intron_variant MELA-AU 22 21290371 21290371 single base substitution C T intron_variant MELA-AU 22 21290464 21290464 single base substitution A T intron_variant MELA-AU 22 21290837 21290837 single base substitution C T intron_variant MELA-AU 22 21291793 21291793 single base substitution G A intron_variant MELA-AU 22 21292245 21292245 single base substitution C T intron_variant MELA-AU 22 21292540 21292540 single base substitution T A intron_variant MELA-AU 22 21292545 21292545 single base substitution T C intron_variant MELA-AU 22 21293253 21293253 single base substitution A T intron_variant MELA-AU 22 21293845 21293845 single base substitution C T intron_variant MELA-AU 22 21293969 21293969 single base substitution G A intron_variant MELA-AU 22 21295334 21295334 single base substitution G A intron_variant MELA-AU 22 21297281 21297281 single base substitution C T intron_variant MELA-AU 22 21298076 21298077 multiple base substitution (>=2bp and <=200bp) TT AG intron_variant MELA-AU 22 21299046 21299046 single base substitution T C intron_variant MELA-AU 22 21299267 21299267 single base substitution C T intron_variant MELA-AU 22 21299312 21299312 single base substitution C T intron_variant MELA-AU 22 21299652 21299652 single base substitution C T intron_variant MELA-AU 22 21300445 21300446 multiple base substitution (>=2bp and <=200bp) CC TT intron_variant MELA-AU 22 21302066 21302066 single base substitution C T intron_variant MELA-AU 22 21302267 21302267 single base substitution C T intron_variant MELA-AU 22 21302375 21302375 single base substitution C T intron_variant MELA-AU 22 21303344 21303344 single base substitution C T intron_variant MELA-AU 22 21303909 21303909 single base substitution C T intron_variant MELA-AU 22 21304107 21304108 multiple base substitution (>=2bp and <=200bp) CC TT exon_variant MELA-AU 22 21304107 21304108 multiple base substitution (>=2bp and <=200bp) CC TT missense_variant P296F 886CC>TT MELA-AU 22 21305292 21305292 single base substitution C T 3_prime_UTR_variant MELA-AU 22 21305292 21305292 single base substitution C T intron_variant MELA-AU 22 21305476 21305476 single base substitution C T 3_prime_UTR_variant MELA-AU 22 21305476 21305476 single base substitution C T intron_variant MELA-AU 22 21305940 21305940 single base substitution C T 3_prime_UTR_variant MELA-AU 22 21305940 21305940 single base substitution C T intron_variant MELA-AU 22 21308173 21308173 single base substitution C T downstream_gene_variant MELA-AU 22 21308530 21308530 single base substitution G T downstream_gene_variant ORCA-IN 22 21270399 21270399 single base substitution G A upstream_gene_variant ORCA-IN 22 21272471 21272471 single base substitution C A exon_variant ORCA-IN 22 21272471 21272471 single base substitution C A synonymous_variant A83A 249C>A ORCA-IN 22 21288487 21288487 single base substitution G C exon_variant ORCA-IN 22 21288487 21288487 single base substitution G C missense_variant Q244H 732G>C ORCA-IN 22 21298795 21298795 single base substitution C T intron_variant ORCA-IN 22 21299191 21299191 single base substitution A G intron_variant ORCA-IN 22 21307712 21307712 single base substitution A C 3_prime_UTR_variant OV-AU 22 21268426 21268426 single base substitution C T upstream_gene_variant OV-AU 22 21270792 21270792 single base substitution G A upstream_gene_variant OV-AU 22 21270972 21270972 single base substitution A C upstream_gene_variant OV-AU 22 21283502 21283502 single base substitution G C intron_variant OV-AU 22 21289740 21289740 single base substitution T C intron_variant OV-AU 22 21292521 21292521 single base substitution C A intron_variant OV-AU 22 21298739 21298739 single base substitution C G intron_variant OV-AU 22 21304678 21304678 single base substitution G T 3_prime_UTR_variant OV-AU 22 21304678 21304678 single base substitution G T intron_variant OV-AU 22 21309134 21309134 single base substitution C G downstream_gene_variant OV-AU 22 21311250 21311250 single base substitution G C downstream_gene_variant PACA-AU 22 21266725 21266725 single base substitution G A upstream_gene_variant PACA-AU 22 21268459 21268459 single base substitution G A upstream_gene_variant PACA-AU 22 21270632 21270632 single base substitution T A upstream_gene_variant PACA-AU 22 21276974 21276974 deletion of <=200bp T - intron_variant PACA-AU 22 21281336 21281336 single base substitution A T intron_variant PACA-AU 22 21281696 21281696 single base substitution T G intron_variant PACA-AU 22 21283437 21283441 deletion of <=200bp ATTTT - intron_variant PACA-AU 22 21293382 21293382 single base substitution C T intron_variant PACA-AU 22 21296819 21296826 deletion of <=200bp ACATTGAC - intron_variant PACA-AU 22 21297542 21297542 single base substitution G C intron_variant PACA-AU 22 21297548 21297548 single base substitution G T intron_variant PACA-AU 22 21301391 21301391 single base substitution G A intron_variant PACA-AU 22 21308433 21308433 single base substitution C T downstream_gene_variant PACA-CA 22 21271475 21271475 single base substitution C T upstream_gene_variant PACA-CA 22 21279009 21279009 single base substitution G A intron_variant PACA-CA 22 21280218 21280218 single base substitution T C intron_variant PACA-CA 22 21286731 21286731 insertion of <=200bp - T intron_variant PACA-CA 22 21287369 21287369 deletion of <=200bp A - intron_variant PACA-CA 22 21288409 21288409 single base substitution A C exon_variant PACA-CA 22 21288409 21288409 single base substitution A C synonymous_variant A218A 654A>C PACA-CA 22 21292538 21292538 deletion of <=200bp T - intron_variant PACA-CA 22 21303483 21303483 single base substitution G A intron_variant PACA-CA 22 21304678 21304678 single base substitution G T 3_prime_UTR_variant PACA-CA 22 21304678 21304678 single base substitution G T intron_variant PACA-CA 22 21311521 21311521 single base substitution T G downstream_gene_variant PBCA-DE 22 21270517 21270517 single base substitution G T upstream_gene_variant PBCA-DE 22 21275256 21275256 single base substitution T A intron_variant PBCA-DE 22 21285230 21285231 deletion of <=200bp AA - intron_variant PBCA-DE 22 21312295 21312295 single base substitution C T downstream_gene_variant PBCA-DE 22 21312429 21312429 single base substitution G A downstream_gene_variant PRAD-UK 22 21300112 21300112 single base substitution T A intron_variant PRAD-UK 22 21302729 21302729 single base substitution C T intron_variant PRAD-UK 22 21304201 21304201 single base substitution C G 3_prime_UTR_variant PRAD-UK 22 21307651 21307651 single base substitution C G 3_prime_UTR_variant READ-US 22 21288457 21288457 single base substitution G A exon_variant READ-US 22 21288457 21288457 single base substitution G A synonymous_variant Q234Q 702G>A READ-US 22 21304053 21304053 single base substitution G A exon_variant READ-US 22 21304053 21304053 single base substitution G A missense_variant E278K 832G>A RECA-EU 22 21286617 21286617 single base substitution C T intron_variant RECA-EU 22 21290437 21290437 single base substitution G A intron_variant RECA-EU 22 21302944 21302944 single base substitution A G intron_variant RECA-EU 22 21308649 21308649 single base substitution A G downstream_gene_variant SKCA-BR 22 21267591 21267591 single base substitution T G upstream_gene_variant SKCA-BR 22 21268644 21268644 single base substitution C T upstream_gene_variant SKCA-BR 22 21269693 21269694 deletion of <=200bp TA - upstream_gene_variant SKCA-BR 22 21270964 21270967 deletion of <=200bp AAAG - upstream_gene_variant SKCA-BR 22 21271653 21271653 single base substitution G A upstream_gene_variant SKCA-BR 22 21271657 21271657 single base substitution G A upstream_gene_variant SKCA-BR 22 21272730 21272730 single base substitution T C intron_variant SKCA-BR 22 21272733 21272734 deletion of <=200bp CT - intron_variant SKCA-BR 22 21273025 21273025 single base substitution T G intron_variant SKCA-BR 22 21274786 21274786 insertion of <=200bp - CA intron_variant SKCA-BR 22 21281801 21281801 insertion of <=200bp - CGTT intron_variant SKCA-BR 22 21281802 21281802 single base substitution T G intron_variant SKCA-BR 22 21285966 21285966 single base substitution C T intron_variant SKCA-BR 22 21286191 21286191 single base substitution C T intron_variant SKCA-BR 22 21286342 21286342 single base substitution G A intron_variant SKCA-BR 22 21288405 21288405 single base substitution C G exon_variant SKCA-BR 22 21288405 21288405 single base substitution C G missense_variant P217R 650C>G SKCA-BR 22 21289093 21289094 deletion of <=200bp AT - intron_variant SKCA-BR 22 21289810 21289810 insertion of <=200bp - CT intron_variant SKCA-BR 22 21290612 21290612 single base substitution C T intron_variant SKCA-BR 22 21293695 21293696 deletion of <=200bp AT - intron_variant SKCA-BR 22 21298427 21298427 insertion of <=200bp - CTT intron_variant SKCA-BR 22 21299767 21299767 single base substitution A T intron_variant SKCA-BR 22 21299995 21299995 single base substitution C T intron_variant SKCA-BR 22 21302109 21302109 single base substitution G T intron_variant SKCA-BR 22 21304950 21304950 single base substitution C T 3_prime_UTR_variant SKCA-BR 22 21304950 21304950 single base substitution C T intron_variant SKCA-BR 22 21307712 21307715 deletion of <=200bp AAAC - 3_prime_UTR_variant SKCA-BR 22 21307744 21307744 single base substitution A G 3_prime_UTR_variant SKCA-BR 22 21309771 21309771 single base substitution T G downstream_gene_variant SKCA-BR 22 21312153 21312153 single base substitution G A downstream_gene_variant SKCM-US 22 21288222 21288222 single base substitution C T exon_variant SKCM-US 22 21288222 21288222 single base substitution C T missense_variant P156L 467C>T SKCM-US 22 21288339 21288339 single base substitution C T exon_variant SKCM-US 22 21288339 21288339 single base substitution C T missense_variant S195F 584C>T SKCM-US 22 21304075 21304075 deletion of <=200bp T - exon_variant SKCM-US 22 21304075 21304075 deletion of <=200bp T - frameshift_variant L285 STAD-US 22 21272475 21272475 single base substitution C T exon_variant STAD-US 22 21272475 21272475 single base substitution C T synonymous_variant L85L 253C>T STAD-US 22 21288079 21288079 single base substitution A T exon_variant STAD-US 22 21288079 21288079 single base substitution A T synonymous_variant P108P 324A>T STAD-US 22 21288167 21288167 single base substitution G T exon_variant STAD-US 22 21288167 21288167 single base substitution G T missense_variant D138Y 412G>T UCEC-US 22 21272307 21272307 single base substitution C T exon_variant UCEC-US 22 21272307 21272307 single base substitution C T stop_gained Q29* 85C>T UCEC-US 22 21288128 21288128 single base substitution C A exon_variant UCEC-US 22 21288128 21288128 single base substitution C A missense_variant L125M 373C>A UCEC-US 22 21288222 21288222 single base substitution C A exon_variant UCEC-US 22 21288222 21288222 single base substitution C A missense_variant P156H 467C>A UCEC-US 22 21288426 21288426 single base substitution G T exon_variant UCEC-US 22 21288426 21288426 single base substitution G T missense_variant G224V 671G>T UCEC-US 22 21304053 21304053 single base substitution G A exon_variant UCEC-US 22 21304053 21304053 single base substitution G A missense_variant E278K 832G>A UCEC-US 22 21304087 21304087 single base substitution C T exon_variant UCEC-US 22 21304087 21304087 single base substitution C T missense_variant T289M 866C>T UCEC-US 22 21304088 21304088 single base substitution G A exon_variant UCEC-US 22 21304088 21304088 single base substitution G A synonymous_variant T289T 867G>A

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand ESCC_124 COSM5641012 c.124T>A p.S42T Substitution - Missense 22:20918058-20918058 + S12-11594-TP COSM4991464 c.109C>T p.L37F Substitution - Missense 22:20918043-20918043 + TCGA-G7-6790-01 COSM3992039 c.37G>C p.A13P Substitution - Missense 22:20917971-20917971 + TCGA-DK-A2I4-01 COSM3800050 c.81G>A p.R27R Substitution - coding silent 22:20918015-20918015 + TCGA-B5-A0JZ-01 COSM1032394 c.467C>A p.P156H Substitution - Missense 22:20933934-20933934 + TCGA-ER-A198-06 COSM3552347 c.467C>T p.P156L Substitution - Missense 22:20933934-20933934 + 29T COSM3713655 c.249C>A p.A83A Substitution - coding silent 22:20918183-20918183 + DM10 COSM5608150 c.490C>A p.R164R Substitution - coding silent 22:20933957-20933957 + 7T COSM3713623 c.732G>C p.Q244H Substitution - Missense 22:20934199-20934199 + TCGA-BS-A0UV-01 COSM1032396 c.832G>A p.E278K Substitution - Missense 22:20949765-20949765 + TCGA-C8-A130-01 COSM444739 c.74A>G p.Q25R Substitution - Missense 22:20918008-20918008 + TCGA-BG-A0M0-01 COSM1032392 c.85C>T p.Q29* Substitution - Nonsense 22:20918019-20918019 + TCGA-63-5131-01 COSM725526 c.631C>G p.Q211E Substitution - Missense 22:20934098-20934098 + CSCC-56-T COSM4550039 c.48G>A p.M16I Substitution - Missense 22:20917982-20917982 + S07-39193-TP COSM4991463 c.27G>A p.S9S Substitution - coding silent 22:20917961-20917961 + TCGA-CD-A4MG-01 COSM4102807 c.253C>T p.L85L Substitution - coding silent 22:20918187-20918187 + DM12 COSM5611250 c.200_201CC>TT p.P67L Substitution - Missense 22:20918134-20918135 + LUAD-B01811 COSM334358 c.731A>T p.Q244L Substitution - Missense 22:20934198-20934198 + TCGA-32-2638-01 COSM3405524 c.305C>T p.A102V Substitution - Missense 22:20918239-20918239 + DM10 COSM5608148 c.406G>T p.G136W Substitution - Missense 22:20933873-20933873 + B70-Tumor COSM1751749 c.341C>T p.S114L Substitution - Missense 22:20933808-20933808 + 37 COSM725526 c.631C>G p.Q211E Substitution - Missense 22:20934098-20934098 + YUDIVI COSM5393191 c.408G>A p.G136G Substitution - coding silent 22:20933875-20933875 + CHC303T COSM5347434 c.182_194del13 p.Y61fs*86 Deletion - Frameshift 22:20918116-20918128 + B70 COSM1751749 c.341C>T p.S114L Substitution - Missense 22:20933808-20933808 + NCI-H23 COSM1196270 c.353T>G p.L118R Substitution - Missense 22:20933820-20933820 + OSCC-GB_00290111 COSM3713655 c.249C>A p.A83A Substitution - coding silent 22:20918183-20918183 + TCGA-BR-8680-01 COSM4102809 c.412G>T p.D138Y Substitution - Missense 22:20933879-20933879 + T207 COSM4674734 c.382G>A p.V128I Substitution - Missense 22:20933849-20933849 + TCGA-EI-6917-01 COSM3424053 c.702G>A p.Q234Q Substitution - coding silent 22:20934169-20934169 + ESCC_BICR_033T COSM5439739 c.191A>T p.N64I Substitution - Missense 22:20918125-20918125 + ESO-0292 COSM1241041 c.347C>G p.P116R Substitution - Missense 22:20933814-20933814 + TCGA-AA-A00N-01 COSM274663 c.434A>C p.K145T Substitution - Missense 22:20933901-20933901 + LUAD-NYU802 COSM376394 c.822G>C p.Q274H Substitution - Missense 22:20949755-20949755 + MDS-08 COSM210955 c.440G>T p.G147V Substitution - Missense 22:20933907-20933907 + TCGA-AX-A0J1-01 COSM1032398 c.867G>A p.T289T Substitution - coding silent 22:20949800-20949800 + B101-Tumor COSM1751748 c.26C>T p.S9L Substitution - Missense 22:20917960-20917960 + TCGA-EB-A431-01 COSM3552348 c.584C>T p.S195F Substitution - Missense 22:20934051-20934051 + LUAD-S01345 COSM397149 c.530A>G p.Y177C Substitution - Missense 22:20933997-20933997 + Pat_41_B COSM5858976 c.375delG p.E126fs*25 Deletion - Frameshift 22:20933842-20933842 + TCGA-A5-A0VQ-01 COSM1032395 c.671G>T p.G224V Substitution - Missense 22:20934138-20934138 + LUAD-S01356 COSM398145 c.454A>T p.I152L Substitution - Missense 22:20933921-20933921 + TCGA-85-6561-01 COSM725527 c.448C>T p.L150L Substitution - coding silent 22:20933915-20933915 + PCSI_0174_Pa_P_526 COSM4962933 c.654A>C p.A218A Substitution - coding silent 22:20934121-20934121 + LUAD-RT-S01866 COSM385166 c.502G>T p.G168C Substitution - Missense 22:20933969-20933969 + TCGA-G4-6628-01 COSM1415031 c.136G>T p.G46W Substitution - Missense 22:20918070-20918070 + 1N62-VS-1T62 COSM4977897 c.114C>T p.V38V Substitution - coding silent 22:20918048-20918048 + TCGA-AA-3492-01 COSM1415033 c.614A>G p.H205R Substitution - Missense 22:20934081-20934081 + B101 COSM1751748 c.26C>T p.S9L Substitution - Missense 22:20917960-20917960 + 587220 COSM1202296 c.437A>G p.K146R Substitution - Missense 22:20933904-20933904 + TCGA-BR-6452-01 COSM4102808 c.324A>T p.P108P Substitution - coding silent 22:20933791-20933791 + TCGA-F5-6814-01 COSM1032396 c.832G>A p.E278K Substitution - Missense 22:20949765-20949765 + CHLA-258 COSM4582224 c.37G>A p.A13T Substitution - Missense 22:20917971-20917971 + TCGA-46-3769-01 COSM725525 c.771A>C p.A257A Substitution - coding silent 22:20934238-20934238 + OSCC-GB_00070111 COSM3713623 c.732G>C p.Q244H Substitution - Missense 22:20934199-20934199 + 2318491 COSM4776596 c.335C>G p.S112C Substitution - Missense 22:20933802-20933802 + H23 COSM1196270 c.353T>G p.L118R Substitution - Missense 22:20933820-20933820 + TCGA-AP-A051-01 COSM1032397 c.866C>T p.T289M Substitution - Missense 22:20949799-20949799 + RK211_C01 COSM3740360 c.465G>A p.K155K Substitution - coding silent 22:20933932-20933932 + PD13764a COSM5794264 c.417C>G p.A139A Substitution - coding silent 22:20933884-20933884 + TCGA-AP-A059-01 COSM1032393 c.373C>A p.L125M Substitution - Missense 22:20933840-20933840 + 1N62-VS-1T62 COSM4977898 c.270C>T p.I90I Substitution - coding silent 22:20918204-20918204 +

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.5613 22q11.21 602007 2421361|CGAP|BC043500|G/T|non-coding||4849|Candidate; 2421364|CGAP|BC043500|C/T|non-coding||4286|Validated; 2391049|dbSNP|BC043500|A/G|non-coding||1636|Validated; 2391049|dbSNP|BC043500|C/T|non-coding||1691|Validated

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A C Synonymous p.A257A c.771A>C 22 21288526 LUSC A G IntronicSNV . c.778-3024A>G 22 21300975 HC A G Missense p.Q25R c.74A>G 22 21272296 BRCA C A Missense p.P156H c.467C>A 22 21288222 UCEC C A Missense p.R11S c.31C>A 22 21272253 CM C A Synonymous p.L37L c.111C>A 22 21272333 LUAD C G Missense p.L131V c.391C>G 22 21288146 LUAD C G Missense p.Q211E c.631C>G 22 21288386 LUSC C T Missense p.A102V c.305C>T 22 21272527 GBM C T Missense p.P156L c.467C>T 22 21288222 CM C T Nonsense p.Q29* c.85C>T 22 21272307 UCEC C T Synonymous p.L150L c.448C>T 22 21288203 LUSC G A Missense p.E278K c.832G>A 22 21304053 HNSC G A Synonymous p.R27R c.81G>A 22 21272303 BLCA G C 3-UTRSNV . c.909+3286G>C 22 21307416 HC G T Missense p.G224V c.671G>T 22 21288426 UCEC T - Frameshift p.F286Sfs*46 c.857delT 22 21304075 CM