PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus TOM1 ME1 22863883 biogrid exp GP GP G G GP GP G GP GP G G GP GP G G GP GP G GP G G G G G GP GP GP GP G TOM1 UBE2D1 19578373 biogrid exp GP G G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP GP G GP G GP GP GP G TOM1 NEDD4 19953087 biogrid exp GP GP G GP P G GP GP GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP P G TOM1 GARS 22863883 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 RPS27 21988832 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TOM1 MYO19 26496610 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TOM1 HIST1H1E 22863883 biogrid exp P P G GP P P P P P P P GP P P P P P P P P P P P TOM1 WDR12 22863883 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TOM1 UBB i2d exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 SSBP2 21988832 biogrid,intact exp GP GP G G GP GP G GP GP G GP P GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ILVBL TOM1 21988832 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TOM1 EEA1 14613930 hprd,intact exp GP GP G G GP GP G G GP G GP G GP G G GP GP GP GP G GP GP GP GP GP G GP GP G TOM1 PTBP2 21988832 biogrid,intact exp G G G G G G G G G G G G G G G G G G GP G G G G G G G G GP G TOM1 TSG101 18367816 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 YAP1 22863883 biogrid exp GP GP G P GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 NTRK1 25921289 biogrid exp P P P G P P P P P P P P P P P P P P P TOM1 MYO6 23023224 biogrid exp GP GP G GP G G GP G GP GP GP G G GP GP G GP G GP GP GP P GP G GP GP TOM1 ZNF512B 15231748 biogrid,i2d,mint,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G TOM1 RPS27A i2d exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 RAC1 21291504 biogrid exp GP GP G G GP G G G GP G G G GP G G GP G G GP G GP GP G GP GP G GP GP G TOM1 APP 21832049 biogrid exp G GP G G GP GP G G GP G G G G G G GP GP G GP G GP GP G G GP G G GP G TOM1 MAP3K1 25260751 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 TBCD 22863883 biogrid exp G G G G G GP G GP GP G GP GP GP G G GP GP G G G GP G G GP GP G GP GP G TOM1 VCP 23383273 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 EXOSC4 22863883 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G XPO1 TOM1 26673895 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 DOHH 26344197 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 DDI2 26344197 biogrid exp P P P P P P P P P P P P P P P TOM1 UBA52 i2d exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 TOLLIP 25416956,20936779,15047686,16412388,14563850, 25402006, 21836163 hprd,biogrid,i2d,intact exp, ortho, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G TOM1 UBC 17550899,23314748,15047686,16196087,16199040, 21836163 biogrid,i2d exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 CLTC 16412388,14563850,15657082, 21836163 hprd,biogrid,bci exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G HGS TOM1 15611048, 25402006, 23023127 mint,intact exp, pred GP GP G G GP GP G GP GP G GP G GP G G GP GP GP GP G GP GP GP GP GP G GP GP G PARK2 TOM1 23503661, 23023127 biogrid exp, pred P GP G P GP G GP GP G GP P P G P GP GP P G P GP GP GP P GP G TOM1 IL1R1 17113392, 25402006 biogrid exp, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TOM1 TOM1L1 19798056, 25402006, 23023127 mint,intact exp, pred GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1 ZFYVE16 14613930, 21836163 hprd,biogrid,i2d,intact,bci exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G TOM1 YWHAE ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 EED ortho GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G TOM1 AP2B1 ortho G GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G TOM1 RAB9B 23023127 pred P P G GP G GP GP G P P P G GP GP GP GP G GP GP GP GP GP GP G TOM1 SQSTM1 23023127 pred GP GP G G GP G G G GP G GP GP GP GP G GP G GP GP G GP GP GP GP GP GP GP GP G TOM1 ATP6V0C 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TOM1 MYO7B 23023127 pred P P G G G P P P GP G GP G G G G P GP G GP G P G TOM1 WBP2 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TOM1 SUMO3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 SPTBN1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KALRN TOM1 16082366 pred P P G P GP G P P G P P P P P GP P P P P P P GP P P TOM1 CHMP5 23023127 pred G GP G G G GP G GP GP G GP G G G G GP GP G GP G GP GP G G GP G GP GP G TOM1 TRAK1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TOM1 STX12 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP G GP GP G TOM1 EPN2 23023127 pred P P P P P P P TOM1 SNX1 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G G GP GP G GP G GP GP G TOM1 UBL4A 23023127 pred GP GP G G G GP G G GP G GP G G G G G GP G GP G GP G G G G G GP P G STX6 TOM1 23023127 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G TOM1 RAD23A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 PARD6A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G TOM1 SORL1 16082366 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 MAPK14 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G STX7 TOM1 23023127, 16082366 pred G G G G G G G G GP G GP G G GP G G G G G G G G G G G GP GP GP G TOM1 M6PR 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G STX10 TOM1 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 UBXN7 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G STX16 TOM1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 UBC 23023127 pred TOM1 C3 23023127 pred GP G G G G G G G GP GP G GP G G G G G G GP G G G G G GP G G TOM1 SF3A1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 SUMO4 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G G GP GP GP G GP GP GP GP G GP GP GP G TOM1 NSFL1C 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G TOM1 PICK1 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G TOM1 HERPUD1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G DCDC2B TOM1 23023127 pred P G G G G G G P TOM1 STX1A 23023127 pred G G G GP G G P G G G G GP GP GP G G G G G GP GP G G TOM1 ADRB2 23023127 pred GP G G G GP G G G GP G P GP GP G G GP G G GP G GP GP G G GP GP GP GP G TOM1 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G TOM1 SNX32 23023127 pred P P G P GP P P G P P P P P GP P P P P P P P P P TOM1 MACF1 23023127 pred TOM1 STX11 23023127 pred GP P G GP P P GP P P GP P G P P P P GP P P P P GP GP P TOM1 TMUB2 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 RASSF9 23023127 pred G P P P G GP P P P P P P P P P GP P P P P TOM1 LIN7B 23023127 pred G G G G G GP G G GP G G GP G G GP GP GP G G G G GP G GP GP G TOM1 UBXN2B 23023127 pred G GP G G G G G G GP G GP G GP G G GP G GP G G G GP G G GP G GP GP G RGS14 TOM1 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TOM1 STX5 23023127 pred GP GP G G GP GP G G G G GP GP GP GP G G GP G GP G GP GP GP G G G GP GP G TOM1 GHR 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G DCLK1 TOM1 23023127 pred G G G GP G G GP G GP G GP GP GP GP G P G G G GP GP GP P G TOM1 SNX15 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TOM1 APBA1 23023127 pred P GP G P GP G GP P G GP GP P GP G GP GP GP P G P P GP GP GP GP GP GP G ACTN4 TOM1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 UBQLN2 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 PICALM 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G TOM1 TIMM9 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 STX1B 23023127 pred G G G G G TOM1 MYO7A 23023127 pred GP GP G G GP GP G GP GP G GP GP G G G GP GP G GP G GP G GP GP GP G GP GP G TOM1 GOSR1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 SUMO2 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 GABARAPL2 23023127 pred G GP G G GP GP G GP GP G GP G G G G GP GP G GP G G GP GP G GP G GP GP G TOM1 SNX17 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G TOM1 UBTD1 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G G GP GP GP G P G GP G G G GP G TOM1 USP14 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 SH3GL3 23023127 pred G G G G GP G G G G G G G G G GP G GP G G G G G G GP GP G TOM1 FRMD4A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G G GP GP GP GP GP GP GP G TOM1 UBL4B 23023127 pred P P P P P P P P P P P P P P P P P P P P TOM1 IL1RAP 25402006 pred GP P P P P P G GP P G P P G G G P P G GP P G TOM1 RCAN1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G GOSR2 TOM1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G TOM1 UBQLNL 23023127 pred P P P P P P P P G P P P P GP TOM1 HIP1R 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G TOM1 ASCC2 25402006 pred GP GP G G P GP GP GP GP GP GP G GP P GP P G GP GP GP GP GP GP GP GP G TOM1 UPF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TOM1 IGF2R 16082366 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G SPTBN2 TOM1 23023127 pred GP GP G GP G G GP GP P P GP GP G GP GP P P P GP SNX2 TOM1 23023127 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP G G GP GP GP GP G TOM1 SUMO1 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 CLINT1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G TOM1 MSR1 23023127 pred G G GP G G GP G GP G P TOM1 UBXN2A 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TOM1 TOM1L2 23023127 pred G GP G G GP GP G GP GP G GP GP G GP G GP GP G GP G GP GP GP G GP G GP GP G TOM1 PRKCI 23023127 pred GP GP G G G GP G G GP G GP G GP G G GP GP G GP G GP GP G G GP G GP GP G UBFD1 TOM1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 STAM2 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 CHMP3 23023127 pred P P P P P P P P P P P P P P P P P P P P P P TOM1 SH3GL2 23023127 pred G GP G G G GP GP G G TOM1 DNAJC6 23023127 pred G G G G GP G G G G G G GP G G G G DVL1 TOM1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 RHOA 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 DRAP1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 EPB41L3 23023127 pred G GP G GP G G GP G GP G GP G GP GP GP GP G GP G GP G GP TOM1 ITSN1 16082366 pred G GP G G G GP G GP GP G GP GP GP GP G GP GP G G G GP G GP GP GP G GP GP G TOM1 EPB41L4B 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP P GP GP G TOM1 FAF1 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 MIDN 23023127 pred GP GP G G GP GP G GP GP G GP G G G G GP GP G G G GP GP GP GP GP G GP GP G TOM1 CHMP6 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 PPP2R1A 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CIDEA TOM1 23023127 pred G G G G G G G G TOM1 EPB41L5 23023127 pred G GP G G GP GP G G G G GP GP G G G GP GP G GP G GP G G G GP P GP GP G TOM1 UBLCP1 23023127 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 EPN1 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP G GP G GP GP GP GP GP G GP GP G TOM1 VPS4A 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 TLN1 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 FRMD7 23023127 pred P P P P P P P P P P P P P P P P P P P TOM1 GGA1 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G TOM1 UBXN10 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP GP GP GP G GP GP GP GP GP G GP GP G TOM1 UBL7 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G TOM1 RAD23B 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CLTCL1 TOM1 21836163 pred TOM1 BAG6 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 ITSN2 23023127, 16082366 pred G G G G G GP G G GP G GP GP G G G GP GP G GP G GP GP G G GP G GP GP G TOM1 STAM 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP G GP GP G TOM1 ARAF 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TOM1 GGA2 25402006, 23023127 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G TOM1 MCM5 21836163 pred GP P G GP G GP G G GP GP G GP G GP G G GP GP G GP G TOM1 EPN3 23023127 pred GP P P G G GP GP P P GP P GP P GP GP GP P GP P TOM1 UBTD2 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TOM1 EPS15 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 ARFIP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 KRT73 23023127 pred P P P P P P P P P P P P P P P P P P P P TOM1 CHMP7 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP GP GP GP GP GP GP GP G TOM1 UBQLN1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TOM1 STX3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TOM1 EHD1 23023127 pred G G G G G GP G GP GP G GP G GP GP G G GP GP G G GP G G G G GP G GP G TOM1 PACSIN1 23023127 pred G GP G G P G P GP G TOM1 TMUB1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G TOM1 MYB 21836163 pred P P G GP P P GP P P GP GP G GP P GP P P GP GP P GP P GP P G TOM1 UBXN11 23023127 pred G GP G G G GP G GP P G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G TOM1 AMPH 23023127 pred G G G G GP G G GP G G G G G GP G GP G G G G G G G G G TOM1 GABARAP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G FRMD3 TOM1 23023127 pred GP GP G G G GP G GP G G GP GP GP G GP GP GP GP G GP GP G G GP GP GP GP G TOM1 LYST 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TOM1 CIDEC 23023127 pred G GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants O60784 Q96KM6 - 15231748 - X 2 O60784 - 14613930 - X 2 O60784 - 16199040 - X 2 O60784 Q7Z3T8 cosedimentation through density gradient 14613930 physical association X 2 O60784 Q7Z3T8 anti tag coimmunoprecipitation 14613930 physical association X 2 O60784 Q7Z3T8 anti bait coimmunoprecipitation 14613930 physical association X 2 O60784 Q7Z3T8 two hybrid 14613930 physical association X 2 O60784 Q7Z3T8 pull down 14613930 physical association X 2 O60784 Q96KM6 two hybrid 15231748 physical association X 2 O60784 O14964 two hybrid 15611048 physical association X 2 O60784 P0CG53 pull down 16199040 direct interaction X 2 O60784 P0CG53 pull down 16199040 direct interaction X 2 O60784 P0CG53 surface plasmon resonance 16199040 direct interaction X 2 O60784 P0CG53 nuclear magnetic resonance 16199040 direct interaction X 2 O60784 P0CG53 biophysical 16199040 direct interaction X 2 O60784 P0CG53 surface plasmon resonance 20150893 direct interaction X 2 O60784 P42677 two hybrid array 21988832 physical association X 2 O60784 A1L0T0 two hybrid array 21988832 physical association X 2 Q6FIE9 O60784 coimmunoprecipitation 14563850 physical association X 2 Q6FIE9 O60784 two hybrid prey pooling approach 25416956 physical association X 2 Q6FIE9 O60784 two hybrid prey pooling approach 25416956 physical association X 2 Q6FIE9 O60784 two hybrid array 25416956 physical association X 2 Q6FIE9 O60784 two hybrid array 25416956 physical association X 2 Q6FIE9 O60784 validated two hybrid 25416956 physical association X 2 Q6FIE9 O60784 validated two hybrid 25416956 physical association X 2 O60784 ubiquitinase assay 25260751 ubiquitination reaction C 5 O60784 Q15075 cosedimentation through density gradient 14613930 physical association X 2 O75674 O60784 pull down 19798056 physical association X 2 O75674 O60784 pull down 19798056 physical association X 2 P81877 O60784 two hybrid array 21988832 physical association X 2 Q9UKA9 O60784 two hybrid array 21988832 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B HGS TOM1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15611048 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint)|MI:0471(mint) UniProt_81030|MINT_31202|MINT_59798 bait|bait|bait prey|prey|prey TOM1 UBE2D1 MI:0096(pull down) 19578373 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_221539 bait prey TOM1 TOLLIP MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0492(in vitro)|MI:0004(affinity chromatography technology) 14563850,15047686,16412388 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact)|MI:0468(hprd)|(biogrid) BIOGRID_195240|BIOGRID_87807|BIOGRID_87806|BIOGRID_77971|BIOGRID_195245|UniProt_72240|HPRD_13243|BIOGRID_194905 bait|prey|bait|bait|prey|bait|-|bait prey|bait|prey|prey|bait|prey|-|prey TOM1 WDR12 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304406 prey bait TOM1 ILVBL MI:0004(affinity chromatography technology)|MI:0397(two hybrid array) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_286939|UniProt_118191 prey|unspecified role bait|unspecified role TOM1 ZNF512B MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15231748 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|MI:0471(mint)|(biogrid)|MI:0471(mint) UniProt_78497|MINT_31408|BIOGRID_259279|MINT_60173 prey|prey|prey|prey bait|bait|bait|bait TOM1 HIST1H1E MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304388 prey bait TOM1 NEDD4 MI:0415(enzymatic study) 19953087 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_148285 prey bait TOM1 YAP1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_305117 bait prey TOM1 APP MI:0096(pull down) 21832049 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_228516 bait prey PARK2 TOM1 MI:0004(affinity chromatography technology) 23503661 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_271178 bait prey TOM1 RAC1 MI:0004(affinity chromatography technology) 21291504 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_194669 prey bait TOM1 TSG101 MI:0004(affinity chromatography technology) 18367816 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_192330 bait prey TOM1 DIAPH2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22933573 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_220944|BIOGRID_220945|BIOGRID_220943 prey|bait|bait bait|prey|prey TOM1 PTBP2 MI:0004(affinity chromatography technology)|MI:0397(two hybrid array) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_286941|UniProt_118193 prey|unspecified role bait|unspecified role TOM1 MYO6 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 23023224 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_260137|BIOGRID_260135 prey|prey bait|bait TOM1 CLTC MI:0096(pull down)|MI:0492(in vitro)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid) 14563850,15657082,16412388 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|-|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0468(hprd)|(biogrid)|(biogrid) BIOGRID_206983|HPRD_20008|BIOGRID_194908|BIOGRID_87808 bait|-|bait|bait prey|-|prey|prey TOM1 TBCD MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304405 prey bait TOM1 UBC MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 15047686,16196087,16199040,18781797,21139048,21890473,21906983,21963094,21987572,22053931,22505724,23000965,23314748 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_180538|BIOGRID_171370|BIOGRID_267966|BIOGRID_163174|BIOGRID_223210|BIOGRID_264304|BIOGRID_161747|BIOGRID_194620|BIOGRID_247925|BIOGRID_194619|BIOGRID_143088|BIOGRID_223139|BIOGRID_195238|BIOGRID_176446 prey|prey|prey|prey|prey|prey|prey|bait|prey|bait|prey|prey|bait|prey bait|bait|bait|bait|bait|bait|bait|prey|bait|prey|bait|bait|prey|bait TOM1 ME1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_301111 bait prey TOM1 IL1R1 MI:0004(affinity chromatography technology) 17113392 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_122146 prey bait TOM1 SSBP2 MI:0004(affinity chromatography technology)|MI:0397(two hybrid array) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_286940|UniProt_118192 prey|unspecified role bait|unspecified role TOM1 GARS MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304387 prey bait TOM1 EEA1 MI:0018(two hybrid)|MI:0492(in vitro) 14613930 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (intact)|MI:0468(hprd) UniProt_74129|HPRD_13242 neutral component|- neutral component|- TOM1 TOM1L1 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0096(pull down)|MI:0096(pull down) 10,19798056 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(intact)|(intact) MINT_78559|MINT_78558|MINT_46822|MINT_46821|UniProt_103972|UniProt_103973 bait|bait|bait|bait|bait|bait prey|prey|prey|prey|prey|prey TOM1 EXOSC4 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304386 prey bait TOM1 ZFYVE16 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0492(in vitro)|MI:0018(two hybrid)|MI:0018(two hybrid) 14613930 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(intact)|(biogrid)|(intact)|(intact)|MI:0468(hprd)|(intact)|(intact) BIOGRID_87509|BIOGRID_87508|BIOGRID_87507|UniProt_74125|BIOGRID_87506|UniProt_74124|UniProt_74123|HPRD_13244|UniProt_74126|UniProt_74127 bait|prey|bait|prey|prey|bait|prey|-|bait|neutral component prey|bait|prey|bait|bait|prey|bait|-|prey|neutral component TOM1 RPS27 MI:0397(two hybrid array)|MI:0004(affinity chromatography technology) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_117547|BIOGRID_285607 unspecified role|prey unspecified role|bait TOM1 VCP MI:0004(affinity chromatography technology) 23383273 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_249938 prey bait

PPI - HINT Gene A Gene B PMID Method Quality TOM1 UBC 15047686,17550899,16199040,16199040,15047686,23314748 0004,0004,0114,0004,0096,0096 LC TOM1 HIST1H1E 22863883 0401 HT TOM1 GARS 22863883 0401 HT TOM1 ME1 22863883 0401 HT TOM1 CLTC 14563850,14563850,15657082,16412388 0018,0004,0096,0004 LC TOM1 DDI2 26344197 0401 HT TOM1 DKFZP451O0517 22863883 0401 HT TOM1 MYO19 26496610,26496610 0007,0004 HT TOM1 TBCD 22863883 0401 HT TOM1 DOHH 26344197 0401 HT TOM1 WDR12 22863883 0401 HT TOM1 TOLLIP 15047686,14563850,15047686,14563850,14563850,16412388,26320582,14563850,26320582 0096,0004,0004,0019,0018,0004,0114,0096,0096 LC TOM1 EXOSC4 22863883 0401 HT TOM1 HIST1H1E 22863883 0401 HT TOM1 GARS 22863883 0401 HT TOM1 ME1 22863883 0401 HT TOM1 DDI2 26344197 0401 HT TOM1 DKFZP451O0517 22863883 0401 HT TOM1 MYO19 26496610,26496610 0007,0004 HT TOM1 TBCD 22863883 0401 HT TOM1 DOHH 26344197 0401 HT TOM1 WDR12 22863883 0401 HT TOM1 EXOSC4 22863883 0401 HT TOM1 UBC 15047686,17550899,16199040,16199040,15047686,23314748 0004,0004,0114,0004,0096,0096 LC TOM1 CLTC 14563850,14563850,15657082,16412388 0018,0004,0096,0004 LC TOM1 TOLLIP 15047686,14563850,15047686,14563850,14563850,16412388,26320582,14563850,26320582 0096,0004,0004,0019,0018,0004,0114,0096,0096 LC ILVBL TOM1 21988832,21988832 0397,0018 HT HGS TOM1 15611048 0018 LC TOM1 TOM1 10985773 0114 LC TOM1 UBC 16199040,16199040,26320582 0114,0004,0114 LC TOM1 HIST1H1E 22863883 0401 LC TOM1 GARS 22863883 0401 LC TOM1 RPS27 21988832,21988832 0397,0018 HT TOM1 NEDD4 19953087 0415 HT TOM1 ME1 22863883 0401 LC TOM1 UBA52 16199040 0114 LC TOM1 SSBP2 21988832,21988832 0397,0018 HT TOM1 CLTC 14563850,14563850 0018,0004 LC TOM1 MAP3K1 25260751 0415 LC TOM1 EEA1 14613930 0029 LC TOM1 DDI2 26344197 0401 LC TOM1 ZFYVE16 14613930,14613930,14613930,14613930,14613930,14613930,14613930 0029,0004,0018,0019,0006,0007,0096 LC TOM1 DKFZP451O0517 22863883 0401 LC TOM1 ZNF512B 15231748 0018 HT TOM1 TBCD 22863883 0401 LC TOM1 DOHH 26344197 0401 LC TOM1 WDR12 22863883 0401 LC TOM1 TOLLIP 14563850,14563850,14563850,25416956,25416956,25416956,26320582,14563850,25416956,26320582 0004,0019,0018,0397,0018,1356,0114,0096,1112,0096 LC,HT TOM1 SMURF1 20804422 0415 LC TOM1 EXOSC4 22863883 0401 LC TOM1 PTBP2 21988832,21988832 0397,0018 HT TOM1 MYO6 23023224,23023224 0004,0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID O60784 O14964 TOM1 HGS 0.309 15611048 Q5TDH0 O60784 DDI2 TOM1 0.081 26344197 Q9HCE7 O60784 SMURF1 TOM1 0.183 20804422 O60784 O60260 TOM1 PARK2 0.126 23503661 Q9GZL7 O60784 WDR12 TOM1 0.081 22863883 Q9NPD3 O60784 EXOSC4 TOM1 0.081 22863883 O75674 O60784 TOM1L1 TOM1 0.376 19798056 P05067 O60784 APP TOM1 0.183 21832049 P0CH28 O60784 UBC TOM1 0.309 20150893 P46937 O60784 YAP1 TOM1 0.081 22863883 P48163 O60784 ME1 TOM1 0.081 22863883 P51668 O60784 UBE2D1 TOM1 0.309 19578373 Q6FIE9 O60784 TOLLIP {ECO:0000313|EMBL:CAG38508.1} TOM1 0.332 25416956 Q99816 O60784 TSG101 TOM1 0.21 18367816 Q9BU89 O60784 DOHH TOM1 0.081 26344197 Q62925 O60784 MAP3K1 TOM1 0.033 25260751 P10412 O60784 HIST1H1E TOM1 0.081 22863883 Q6P5F9 O60784 XPO1 TOM1 0.126 26673895 P04629 O60784 NTRK1 TOM1 0.126 25921289 Q9WTI7 O60784 MYO1C TOM1 0.236 26496610 Q9UKA9 O60784 PTBP2 TOM1 0.286 21988832 Q9UM54 O60784 MYO6 TOM1 0.454 23023224 Q8TCA0 O60784 LRRC20 TOM1 0.236 unassigned1304 Q96H55 O60784 MYO19 TOM1 0.236 26496610 Q15038 O60784 DAZAP2 TOM1 0.236 unassigned1304 O60784 C9JJ79 TOM1 PILRA {ECO:0000313|ENSEMBL:ENSP00000390026} 0.236 unassigned1304 O60784 A1L0T0 TOM1 ILVBL 0.286 21988832 Q9BSU3 O60784 NAA11 TOM1 0.236 unassigned1304 Q7Z3T8 O60784 ZFYVE16 TOM1 0.92 14613930 P42677 O60784 RPS27 TOM1 0.286 21988832 P0CG48 O60784 UBC TOM1 0.765 16196087,26320582,23314748,17550899,16199040 P0CG53 O60784 UBB TOM1 0.891 16199040,20150893 Q00610 O60784 CLTC TOM1 0.569 14563850,16412388,15657082 Q99732 O60784 LITAF TOM1 0.396 unassigned1304,25963657 Q9H0E2 O60784 TOLLIP TOM1 0.963 25416956,16412388,26320582,14563850,unassigned1304,15047686 Q96KM6 O60784 ZNF512B TOM1 0.332 15231748 Q9BTW9 O60784 TBCD TOM1 0.081 22863883 P46934 O60784 NEDD4 TOM1 0.183 19953087 P41250 O60784 GARS TOM1 0.081 22863883 P81877 O60784 SSBP2 TOM1 0.286 21988832 P14778 O60784 IL1R1 TOM1 0.21 17113392 P63000 O60784 RAC1 TOM1 0.21 21291504 Q15075 O60784 EEA1 TOM1 0.21 14613930 Q13233 O60784 MAP3K1 TOM1 0.183 25260751 Q2TBE6 O60784 PI4K2A TOM1 0.21 23146885 P55072 O60784 VCP TOM1 0.126 23383273

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 ILVBL TOM1 MI:0045 experimental interaction detection MI:0461 interaction database MYO1C TOM1 MI:0362 inference MI:0461 interaction database HGS TOM1 MI:0045 experimental interaction detection MI:0461 interaction database XPO1 TOM1 MI:0045 experimental interaction detection MI:0461 interaction database PARK2 TOM1 MI:0045 experimental interaction detection MI:0461 interaction database TOM1 EED MI:0362 inference MI:0461 interaction database TOM1 TOM1L1 MI:0045 experimental interaction detection MI:0461 interaction database TOM1 NTRK1 MI:0045 experimental interaction detection MI:0461 interaction database TOM1 APP MI:0045 experimental interaction detection MI:0461 interaction database TOM1 UBB MI:0045 experimental interaction detection MI:0461 interaction database TOM1 UBC MI:0045 experimental interaction detection MI:0461 interaction database TOM1 IL1R1 MI:0045 experimental interaction detection MI:0461 interaction database TOM1 ATF2 MI:0045 experimental interaction detection MI:0461 interaction database TOM1 HNF4A MI:0045 experimental interaction detection MI:0461 interaction database TOM1 RPS27 MI:0045 experimental interaction detection MI:0461 interaction database TOM1 NEDD4 MI:0045 experimental interaction detection MI:0461 interaction database TOM1 UBE2D1 MI:0045 experimental interaction detection MI:0461 interaction database TOM1 APLP1 MI:0362 inference MI:0461 interaction database TOM1 VCP MI:0045 experimental interaction detection MI:0461 interaction database TOM1 RPS27A MI:0045 experimental interaction detection MI:0461 interaction database TOM1 UBA52 MI:0045 experimental interaction detection MI:0461 interaction database TOM1 RAC1 MI:0045 experimental interaction detection MI:0461 interaction database TOM1 AP2B1 MI:0362 inference MI:0461 interaction database TOM1 SSBP2 MI:0045 experimental interaction detection MI:0461 interaction database TOM1 CLTC MI:0045 experimental interaction detection MI:0461 interaction database TOM1 MAP3K1 MI:0045 experimental interaction detection MI:0461 interaction database TOM1 EEA1 MI:0045 experimental interaction detection MI:0461 interaction database TOM1 TOM1L2 MI:0362 inference MI:0461 interaction database TOM1 ZFYVE16 MI:0045 experimental interaction detection MI:0461 interaction database TOM1 MYO19 MI:0045 experimental interaction detection MI:0461 interaction database TOM1 ZNF512B MI:0045 experimental interaction detection MI:0461 interaction database TOM1 LITAF MI:0045 experimental interaction detection MI:0461 interaction database TOM1 TSG101 MI:0045 experimental interaction detection MI:0461 interaction database TOM1 PI4K2A MI:0362 inference MI:0461 interaction database TOM1 TOLLIP MI:0045 experimental interaction detection MI:0461 interaction database TOM1 PTBP2 MI:0045 experimental interaction detection MI:0461 interaction database TOM1 MYO6 MI:0045 experimental interaction detection MI:0461 interaction database