PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus MLH1 NCF4 20706999 intact exp G G G GP G GP GP G G G G GP G TXN NCF4 10397171 hprd,biogrid,bci exp G G G G G GP GP G G G G GP G XRCC6 NCF4 9914162 hprd,biogrid,bci exp G G G GP G GP GP G G G G GP G PRKDC NCF4 9914162 biogrid exp G G G GP G GP GP G G G G GP G NCF2 NCF4 16297854,16782902,10672014,9083043,9490029,12887891,12813044,8760383,11893732,10486263,11483497,11796733, 25402006, 23023127, 21836163 innatedb,hprd,biogrid,i2d,mint,intact,dip,bci exp, ortho, pred G G GP GP GP G G G GP G NCF1 NCF4 9083043,11893732,15657040,11258927,11796733, 25402006, 23023127, 21836163 hprd,biogrid,mint,intact exp, ortho, pred P P P P MSN NCF4 11716484, 25402006, 23023127, 21836163 hprd,biogrid,bci exp, pred G G G GP G GP GP G G G G GP G CYBA NCF4 17803994,11893732, 25402006, 21836163 hprd,mint,intact,bci exp, pred G G G GP G GP GP G G G G GP G CYBB NCF4 11893732, 25402006, 21836163 hprd,bci exp, pred G G G GP G GP G G G G G GP G CORO1A NCF4 9365277, 25402006 hprd,bci exp, pred G G GP G G GP G G G G GP G PRKCD NCF4 9804763, 25402006, 23023127 hprd,bci exp, pred G G G GP G GP GP G G G G GP G NCF4 GBP7 ortho P P HDAC4 NCF4 25402006 ortho, pred G G G GP G GP GP G G G GP G TGFB1I1 NCF4 23023127 pred G G G GP G GP GP G G G G GP G NCF4 THEMIS2 25402006 pred G G G G G GP G G G G G G G NCF4 SH3PXD2A 23023127 pred G G G GP G GP G G G G G G G SP100 NCF4 23023127 pred G G G GP G GP GP G G G G GP G NCF4 SORBS1 23023127 pred G G G GP G GP G G G G G G G NCF4 NOXO1 23023127 pred G G NCF4 TRIP10 23023127 pred G G G G G G G G G G G G G NCF4 SH3KBP1 23023127 pred G G G GP G G GP G G G G GP G CXCL1 NCF4 23023127 pred G G G G G G G G G G G G G MAP3K10 NCF4 23023127 pred P P P P S100A4 NCF4 23023127 pred G G G GP G GP GP G G G G GP G NCF4 NOX1 25402006, 21836163 pred G G GP G P GP P SYK NCF4 25402006, 23023127 pred G G G GP G GP GP G G G G GP G MAN2B1 NCF4 25402006 pred G G G GP G GP GP G G G G GP G ARHGDIB NCF4 25402006, 23023127 pred G G G GP G GP GP G G G G GP G NCF4 MAP3K11 23023127 pred G G G GP G GP GP G G G G GP G NCF4 UBLCP1 23023127 pred G G G GP G GP GP G G G G GP G FCHSD2 NCF4 23023127 pred G G G GP G GP G G G G G GP G NCF4 STAB1 25402006 pred G G G G G GP GP G G G G GP G NCF4 PEX13 23023127 pred G G G GP G GP GP G G G G GP G KALRN NCF4 23023127 pred P P P GP BTK NCF4 25402006, 23023127 pred G G GP G GP GP G GP G EMP3 NCF4 25402006 pred G G G G G G G G G G G G G NCF4 VAV3 23023127 pred G G G GP G GP GP G G G G GP G MNDA NCF4 25402006 pred G G G GP GP GP G G G GP G NCF4 MAPK14 21836163 pred G G G GP G GP GP G G G G GP G MYO1F NCF4 25402006, 23023127 pred G G G GP G G GP G G G G GP G NCF4 BAIAP2L2 23023127 pred G P P G G P G UBXN2B NCF4 23023127 pred G G G G G GP G G G G G G G NCF4 SGK3 23023127 pred P P P P TRIO NCF4 23023127 pred G G G G G GP GP G G G G GP G NCF4 NSFL1C 23023127 pred G G G GP G GP GP G G G G GP G CRK NCF4 23023127 pred G G G G G G G G G G G G G NCF4 VSIG4 25402006 pred G G G G G GP GP G G G G G G SELL NCF4 25402006 pred G G GP G GP GP G G G G GP G PRKCA NCF4 25402006 pred G G G GP G G GP G G G G G G NCF4 ARHGEF19 23023127 pred G G G G G G G G NCF4 LY96 25402006 pred G G G G G G G G G G G G G ARHGEF7 NCF4 23023127 pred G G G GP G GP GP G G G G GP G POU2F2 NCF4 25402006 pred G G G GP G G GP G G G G G G PRKCB NCF4 25402006 pred G G G GP G GP GP G G G G GP G LIG4 NCF4 25402006 pred G G G GP G GP GP G G G GP G GMFG NCF4 25402006 pred G G G GP G GP GP G G G G G G NCF4 UBASH3B 23023127 pred G GP GP P G GP RAC1 NCF4 25402006 pred G G G GP G GP G G G G G G G NCF4 UBXN11 23023127 pred G G G G GP G G G G G G G NCF4 MLK4 23023127 pred G G GP G GP GP G G G G P G PLCG2 NCF4 23023127 pred G G G GP G GP GP G G G G GP G NCF4 SNX9 23023127 pred G G G GP G GP GP G G G G GP G NCF4 STAC 23023127 pred G G G GP G GP GP G G G G GP G ITGB2 NCF4 25402006 pred G G G GP G GP GP G G G G GP G NCKAP1L NCF4 25402006 pred G G G GP G GP GP G G G G GP G ARHGEF37 NCF4 23023127 pred G G G G G G G G G G G G G FGR NCF4 25402006 pred G G G GP G GP GP G G G GP G NCF4 CD2AP 23023127 pred G G G GP G GP GP G G G G GP G NEDD9 NCF4 23023127 pred G G G GP G GP GP G G G G GP G RIMBP3B NCF4 23023127 pred NCF4 NAA15 25402006 pred G G G GP G GP GP G G G G GP G SLA NCF4 25402006, 23023127 pred G G G GP G GP GP G G G G GP G NCF4 MS4A4A 25402006 pred G G G GP G GP G G G G GP G CFD NCF4 23023127 pred G G G G G GP GP G G G G G G CTSS NCF4 25402006, 23023127 pred G G G GP G GP GP G G G G GP G CCL5 NCF4 25402006, 23023127 pred G G G G G G G G G G G G G CSF1R NCF4 25402006 pred G G G GP G GP GP G G G G GP G FGL2 NCF4 25402006 pred G G G GP G GP GP G G G G GP G LY86 NCF4 25402006 pred G G G GP G GP GP G G G G GP G PRKCI NCF4 16082366 pred G G G G G GP G G G G G G G HLX NCF4 23023127 pred G G G GP G GP GP G G G G GP G NCF4 MYO15B 23023127 pred GRAP NCF4 23023127 pred P G GP GP G GP NCF4 ITSN2 23023127 pred G G G G G G G G G G G G G NCF4 ARHGEF16 23023127 pred G G G GP G GP GP G G G G GP G CTSC NCF4 25402006 pred G G G GP G GP GP G G G G GP G NCF4 NR2E3 21836163 pred SH2D1A NCF4 23023127 pred G G C1QB NCF4 25402006 pred G G G G G G G G G G G G G NCF4 ABI2 23023127 pred G G G G G G G G G G G G G NCF4 UBQLNL 23023127 pred P P P IGSF6 NCF4 23023127 pred G G GP GP GP G G G G NCF4 MYO15A 23023127 pred G G G G G G G G G G G G RHOG NCF4 25402006 pred G G G GP G GP GP G G G G GP G SASH3 NCF4 25402006, 23023127 pred G G G G G GP GP G G G G GP G NCF4 C3AR1 25402006 pred G G G GP G GP GP G G G G G G NCF4 LIMS2 23023127 pred G G G G G G G G G G G G G ALOX5 NCF4 25402006 pred G G G GP G GP GP G G G G GP G NCF4 SLC7A7 25402006 pred G G G G G GP G G G G G G G NCF4 SNX18 23023127 pred G G G GP G GP GP G G G G G G CCL23 NCF4 23023127 pred G G G G G G TYROBP NCF4 25402006 pred G G G GP G GP GP G G G G GP G HCLS1 NCF4 25402006, 23023127 pred G G G GP G GP GP G G G G GP G LST1 NCF4 25402006 pred G G G GP G GP GP G G G G GP G NCF4 STAC2 23023127 pred G G G GP G GP GP G G G G GP G UBASH3A NCF4 23023127 pred G G NCF1C NCF4 23023127 pred NCF4 ABI3 23023127 pred G G G GP G GP GP G G G G GP G RAB27A NCF4 23023127 pred G G G GP G GP GP G G G G GP G NCF4 NGEF 23023127 pred G P G P GP G G G P G TLR2 NCF4 25402006 pred G G G G G G G G G G G G NCF4 SH3GLB2 23023127 pred G G G G G G GP G G G G GP G S100A11 NCF4 25402006 pred G G G GP G GP GP G G G G GP G NCF4 FCHSD1 23023127 pred P P GP GP NCF4 TMUB2 23023127 pred G G G GP G GP GP G G G G GP G PRKCZ NCF4 16082366 pred G G G GP GP G G G G GP G HLA-DPA1 NCF4 25402006 pred G G G G G GP GP G G G G GP G NCF4 BAIAP2 23023127 pred G GP GP GP G P G NCF4 STAC3 23023127 pred G G G G G G G IRF8 NCF4 23023127 pred G G G GP G GP GP G G G G GP G FYN NCF4 23023127 pred G G G GP G G GP G G G G GP G NCF4 RHOH 23023127 pred G G GP G GP GP G G G G GP G ARHGAP4 NCF4 23023127 pred G G G GP G GP GP G G G GP G MYO1E NCF4 23023127 pred G G GP G GP GP G G G G G G NCK1 NCF4 23023127 pred G G G GP G GP GP G G G G GP G NCF4 MIA2 23023127 pred NCF4 SH3RF1 23023127 pred G G G G G G G G G G G G G CD14 NCF4 25402006 pred G G G GP G GP GP G G G G GP G NCF4 MAPK11 21836163 pred G G G GP G GP GP G G GP G ARPC1B NCF4 25402006 pred G G G GP G GP GP G G G G GP G VCAM1 NCF4 21836163 pred G G G G G G GP G G G G GP G NCF4 ARAP1 25402006 pred G G G GP G GP GP G G G G G G WAS NCF4 23023127 pred G G G GP G GP GP G G G G GP G NCF4 DEF6 23023127 pred G G G G GP GP G G G G GP G LCP1 NCF4 25402006 pred G G G GP G GP GP G G G G GP G IKZF1 NCF4 23023127 pred G G G GP G G GP G G G G GP G NCF4 NDRG1 25402006 pred G G G GP G GP GP G G G G GP G LIMS1 NCF4 23023127 pred G G G G G GP GP G G G G GP G NCF4 XRCC6BP1 25402006 pred G G G G G GP GP G G G G GP G RIMBP3C NCF4 23023127 pred HLA-DRA NCF4 25402006 pred G G G GP G GP GP G G G G GP G PTPN6 NCF4 25402006 pred G G G GP G GP GP G G G G GP G NCF4 UBTD1 23023127 pred G G G G G GP G G G G G G MAP3K9 NCF4 23023127 pred G P G P G G G G G GP G NCF4 25402006 pred LYN NCF4 25402006, 23023127 pred G G G GP G GP GP G G G G GP G CCR1 NCF4 25402006 pred G G G G G G G G G G G G G NCF4 SAMSN1 25402006, 23023127 pred G G G GP G GP GP G G GP G FASLG NCF4 25402006 pred G G GP G P G G GP CLU NCF4 25402006 pred G G G GP G G G G G G G G G NCF4 NOXA1 25402006 pred G G G G G G G G G G G G G ARHGEF9 NCF4 23023127 pred G G P G G G G G G G GP G ABL1 NCF4 23023127 pred G G G GP G GP GP G G G G GP G HOXC4 NCF4 25402006 pred G G G G G G G G G G G G G IL10RA NCF4 25402006 pred G G G G G G G G G G G G G NCF4 NOX3 21836163 pred BCAR1 NCF4 23023127 pred G G P G GP GP G G G GP G NCF4 RIMBP3 23023127 pred C1QA NCF4 25402006 pred G G G G G G G G G G G G G LASP1 NCF4 23023127 pred G G G GP G GP GP G G G G GP G CRKL NCF4 23023127 pred G G G GP G GP GP G G G G GP G NPHP1 NCF4 23023127 pred P P LSP1 NCF4 25402006 pred G G G GP G GP GP G G G G GP G SOCS3 NCF4 23023127 pred G G G GP G GP G G G G G G G LYZ NCF4 25402006 pred G G G GP G GP GP G G G G GP G LCP2 NCF4 25402006 pred G G G GP G GP GP G G G G GP G UBC NCF4 23023127 pred NCF4 TMUB1 23023127 pred G G G GP G GP GP G G G G G G ARRB2 NCF4 25402006 pred G G G G G G G G G G G G G HLA-DQB1 NCF4 25402006 pred G G G GP G GP GP G G G G GP G NCF4 EPS8L1 23023127 pred G G G G G G G G G G G NCF4 CD163 25402006 pred G G G GP G GP GP G G G G GP G LCK NCF4 23023127 pred G G GP G G GP G G G GP G NCF4 RUSC1 23023127 pred G G G GP G GP GP G G G G G G ZAP70 NCF4 23023127 pred G G GP G G GP G G GP G NCF4 PARD6G 16082366 pred G G G G G GP G G G G G G G NCF4 RGL3 23023127 pred G G G GP G GP GP G G G G GP G SQSTM1 NCF4 23023127 pred G G G GP G GP GP G G G G GP G NCF4 MAP3K2 16082366 pred G G G G G G G G G G G G G NPC2 NCF4 25402006 pred G G G GP G GP GP G G G G GP G PLEK NCF4 25402006, 23023127 pred G G G GP G GP GP G G G G G G NCF4 NOD2 23023127 pred G GP GP P GP HCK NCF4 25402006, 23023127 pred G G G GP G GP G G G G G GP G NCF4 SH2B3 23023127 pred G G G GP G GP GP G G G G GP G NCF4 NCF4 23023127 pred G G G GP G GP GP G G G G GP G NCF4 SH3RF2 23023127 pred P GRN NCF4 25402006 pred G G G GP G GP GP G G G G GP G GZMA NCF4 25402006, 23023127 pred G G G GP G G G G G G G G RASA1 NCF4 23023127 pred G G G GP G G G G G G G G G NCF4 PARD6A 16082366 pred G G G GP G GP GP G G G GP G ALOX5AP NCF4 25402006 pred G G G GP G GP GP G G G G GP G HLA-E NCF4 25402006 pred G G G GP G GP GP G G G G GP G AIF1 NCF4 25402006 pred G G G GP GP GP G G G G GP G TNFRSF1B NCF4 25402006 pred G G G GP G GP GP G G G G GP G NCF4 SNX11 23023127 pred G G G G G GP GP G G G G GP G CSF2RB NCF4 25402006 pred G G GP G GP GP G G G G GP G NCF4 OSTF1 23023127 pred G G G GP G GP GP G G G G GP G CCL8 NCF4 23023127 pred G G G G G G G G G G G G G NEB NCF4 23023127 pred G P P G G P GRAP2 NCF4 23023127 pred P P P P NCK2 NCF4 23023127 pred G G G GP G GP GP G G G G GP G CEBPA NCF4 25402006 pred G G G GP G GP G G G G G G G EVI2B NCF4 25402006 pred G G G GP G GP GP G G G G GP G FCGR2A NCF4 25402006 pred G G G GP G GP GP G G G G GP G UBXN2A NCF4 23023127 pred G G G G G G G G G G G G G ITK NCF4 23023127 pred G G G G G G G G G G G G MPP1 NCF4 23023127 pred G G G GP G GP G G G G G G G NCF4 SH3RF3 23023127 pred G G G GP G GP GP G G G G GP G FCGR2B NCF4 23023127 pred G G G GP G G GP G G G G GP G NCF4 NOSTRIN 23023127 pred G G P G GP GP G G G G GP G PLD2 NCF4 23023127 pred G G G GP G GP G G G G G G G CD86 NCF4 25402006, 23023127 pred G G G GP GP GP G G G GP G ACTB NCF4 25402006 pred G G G GP G GP GP G G G G GP G SORBS3 NCF4 23023127 pred G G G G G G G G G G G G G LAPTM5 NCF4 25402006 pred G G G GP G GP GP G G G G GP G MAPK8IP2 NCF4 23023127 pred G G G GP G GP GP G G G G GP G TNFAIP8 NCF4 25402006 pred G G G GP G GP GP G G G G GP G NCF4 OBSCN 23023127 pred G P G P GP G G GP G NCF4 BLNK 23023127 pred G G GP G G GP G G G G GP G NCF4 VAMP8 25402006 pred G G G GP G GP GP G G G G GP G NCF4 EPS8L3 23023127 pred G G G GP G GP G G G G G G NCF4 SHE 23023127 pred G G G GP G GP GP G G G G GP G NBR1 NCF4 23023127 pred G G G G G GP GP G G G G G G NCF4 SGSM3 23023127 pred G G G GP G GP GP G G G G GP G BAG6 NCF4 23023127 pred G G G GP G GP GP G G G G GP G FCER1G NCF4 25402006 pred G G G GP G GP GP G G G G GP G NCF4 NOTCH4 23023127 pred G G G G G G G G G G G G G NCF4 RNASE6 25402006 pred G G G GP G G G G G NCF4 SLAMF8 25402006 pred G G G G G G G G G G G CD52 NCF4 25402006 pred G G G G G G G G G G G NCF4 SLA2 23023127 pred G G G G G G G G G G CD53 NCF4 25402006 pred G G G GP G GP GP G G G G GP G CASP1 NCF4 25402006 pred G G G GP G GP GP G G G G G G NCF1B NCF4 23023127 pred VAV1 NCF4 25402006, 23023127 pred G G G GP GP GP G G G GP G CD74 NCF4 25402006, 23023127 pred G G G GP G GP GP G G G G GP G RAC2 NCF4 25402006, 23023127 pred G G G GP G GP GP G G G G GP G NCF4 NOX5 21836163 pred G G GP P G G G NCF4 DOCK2 25402006 pred G G GP G GP GP GP G NCF4 SH3GLB1 23023127 pred G G G GP G GP GP G G G G GP G NCF4 SUMO4 23023127 pred G G G GP G GP GP G G G G GP G NCF4 MS4A6A 25402006 pred G G G GP G GP GP G G G G GP G NCF4 SH3YL1 23023127 pred G G G G G GP GP G G G G G G PSTPIP1 NCF4 23023127 pred G G GP G GP GP G G GP G SRGN NCF4 25402006 pred G G G GP G GP GP G G G G GP G NCF4 LILRB1 25402006 pred G G G G G G NCF4 SKAP1 23023127 pred G G G GP G GP GP G G G G GP G NCF4 MAPK8IP1 23023127 pred P P P P SASH1 NCF4 23023127 pred G G G GP G GP G G G G G G G FYB NCF4 25402006, 23023127 pred G G GP G G GP G G G G GP G NCF4 RUSC2 23023127 pred G G P G GP GP G G GP G NCF4 DNMBP 23023127 pred G G G G G GP G G G G G G G TNFRSF1A NCF4 23023127 pred G G G GP G GP GP G G G G GP G MAPK12 NCF4 21836163 pred G G G G G G GP G G GP G NCF4 OASL 23023127 pred G G G GP G GP GP G G G G G G NCF4 PARD6B 16082366 pred P GP P G G G G G NCF4 EPS8L2 23023127 pred G G G GP G G G G G P G SH3PXD2B NCF4 23023127 pred G G G G G GP G G G G G G G RIMBP2 NCF4 23023127 pred P P G G P G SH3D21 NCF4 23023127 pred G G GP G P GP G G G P NCF4 LAIR1 25402006 pred G G G GP G GP GP G G G G GP G PTPRC NCF4 25402006 pred G G G GP G G GP G G G G GP G NCF4 UBL7 23023127 pred G G G GP G GP GP G G G G GP G ARHGEF6 NCF4 23023127 pred G G G GP G GP GP G G G G G G NCF4 DBNL 23023127 pred G G G GP G GP GP G G G G GP G CD37 NCF4 25402006 pred G G G G G GP G G G G GP G HERPUD1 NCF4 23023127 pred G G G GP G GP GP G G G G GP G PRDX6 NCF4 25402006 pred G G G GP G GP GP G G G G GP G VAV2 NCF4 23023127 pred G G G GP G GP G G G G G GP G NCF4 PLEKHO2 23023127 pred G G G GP G GP GP G G G G GP G LTBP2 NCF4 23023127 pred G G G G G GP G G G G G G G NCF4 ABI1 25402006, 23023127 pred G G G GP G GP GP G G G G GP G RGS14 NCF4 23023127 pred G G G G G GP GP G G G G GP G HLA-DPB1 NCF4 25402006 pred G G G GP G GP GP G G G G GP G NCF4 ITSN1 23023127 pred G G G G G GP GP G G G G G G HLA-DMB NCF4 25402006 pred G G G G G GP GP G G G G GP G KDM4B NCF4 23023127 pred G G G G G G G G G G G G G NCF4 CASS4 23023127 pred P P P G P CXCL12 NCF4 23023127 pred G G G GP G GP GP G G G G GP G NCF4 LILRB2 25402006 pred G G G G G G G G G CTTN NCF4 23023127 pred G G G GP G GP GP G G G G GP G AMPH NCF4 23023127 pred G G G G G G G G G C2 NCF4 23023127 pred G G G G G G G G G G G G G NCF4 AHI1 23023127 pred G G G G G GP GP G G G G GP G CDC42 NCF4 25402006 pred G G G GP G GP GP G G G G GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q15080 P78527-2 enzymatic study 9914162 direct interaction X 2 Q15080 P10599-2 two hybrid 10397171 direct interaction X 2 P19878-4 Q15080 x-ray crystallography 12887891 association X 2 P19878-4 Q15080 two hybrid 12813044 direct interaction X 2 P19878-4 Q15080 affinity chromatography technology 12813044 physical association X 2 P19878-4 Q15080 affinity chromatography technology 16782902 physical association X 2 P19878-4 Q15080 biochemical 11893732 colocalization X 2 P19878-4 Q15080 affinity chromatography technology 11893732 physical association X 2 P19878-4 Q15080 pull down 11796733 direct interaction X 2 P19878-4 Q15080 two hybrid 9083043 direct interaction X 2 P19878-4 Q15080 two hybrid 11483497 direct interaction X 2 P19878-4 Q15080 pull down 11483497 direct interaction X 2 P14598 Q15080 pull down 11796733 direct interaction X 2 P14598 Q15080 pull down 11258927 direct interaction X 2 P14598 Q15080 two hybrid 9083043 direct interaction X 2 P26038 Q15080 affinity chromatography technology 11716484 physical association X 2 P26038 Q15080 pull down 11716484 direct interaction X 2 P0CG48 Q15080 affinity chromatography technology 21890473 physical association X 2 A0A024R1N4 Q15080 two hybrid 9914162 direct interaction X 2 A0A024R1N4 Q15080 pull down 9914162 direct interaction X 2 Q15080 affinity chromatography technology 9490029 physical association X 2 Q15080 two hybrid 9490029 physical association X 2 Q15080 affinity chromatography technology 9490029 physical association X 2 Q15080 filter binding 9490029 physical association X 2 Q15080 two hybrid 9490029 physical association X 2 P13498 Q15080 in vivo 11893732 - X 2 P13498 Q15080 in vivo 11893732 - X 2 Q15080 in vivo 11258927,11893732,7938008,9083043 - C 4 Q15080 in vivo 11258927,11893732,7938008,9083043 - C 4 Q15080 in vivo 11258927,11893732,7938008,9083043 - C 4 Q15080 in vivo 11258927,11893732,7938008,9083043 - C 4 Q15080 in vivo 11258927,11893732,7938008,9083043 - C 4 Q15080 in vivo 11258927,11893732,7938008,9083043 - C 4 Q15080 in vivo 11258927,11893732,7938008,9083043 - C 4 Q15080 in vivo 11258927,11893732,7938008,9083043 - C 4 Q15080 A0A024R611 in vitro 9365277 - X 2 Q15080 A0A024R611 in vitro 9365277 - X 2 P04839 Q15080 in vivo 11893732 - X 2 P04839 Q15080 in vivo 11893732 - X 2 H9ZYJ2 Q15080 two hybrid 10397171 - X 2 H9ZYJ2 Q15080 in vitro 10397171 - X 2 H9ZYJ2 Q15080 two hybrid 10397171 - X 2 H9ZYJ2 Q15080 in vitro 10397171 - X 2 P14598 Q15080 in vitro 11258927,11893732,9083043 - X 2 P14598 Q15080 in vivo 11258927,11893732,9083043 - X 2 P14598 Q15080 in vivo 11258927,11893732,9083043 - X 2 P14598 Q15080 in vitro 11258927,11893732,9083043 - X 2 Q15080 in vitro 9804763 - X 2 Q15080 in vivo 9804763 - X 2 Q15080 in vitro 9804763 - X 2 Q15080 in vivo 9804763 - X 2 P19878 Q15080 in vitro 10486263,10672014,11796733,11893732,12813044 - X 2 P19878 Q15080 two hybrid 10486263,10672014,11796733,11893732,12813044 - X 2 P19878 Q15080 in vivo 10486263,10672014,11796733,11893732,12813044 - X 2 P19878 Q15080 two hybrid 10486263,10672014,11796733,11893732,12813044 - X 2 P19878 Q15080 in vivo 10486263,10672014,11796733,11893732,12813044 - X 2 P19878 Q15080 in vitro 10486263,10672014,11796733,11893732,12813044 - X 2 P26038 Q15080 in vitro 11716484 - X 2 P26038 Q15080 in vivo 11716484 - X 2 P26038 Q15080 in vitro 11716484 - X 2 P26038 Q15080 in vivo 11716484 - X 2 A0A024R1N4 Q15080 in vitro 9914162 - X 2 A0A024R1N4 Q15080 two hybrid 9914162 - X 2 A0A024R1N4 Q15080 in vitro 9914162 - X 2 A0A024R1N4 Q15080 two hybrid 9914162 - X 2 P13498 Q15080 far western blotting 17803994 direct interaction X 2 Q15080 two hybrid 20706999 physical association C 78 Q15080 anti tag coimmunoprecipitation 16782902 association C 4 Q15080 P40692 two hybrid 20706999 physical association X 2 Q5NIP6 Q15080 two hybrid pooling approach 20711500 physical association X 2 P14598 Q15080 classical fluorescence spectroscopy 15657040 direct interaction X 2 P14598 Q15080 x-ray crystallography 15657040 direct interaction X 2 P19878 Q15080 two hybrid 11483497 physical association X 2 P19878 Q15080 x-ray crystallography 12887891 direct interaction X 2 P19878 Q15080 anti bait coimmunoprecipitation 16297854 physical association X 2 P19878 Q15080 anti tag coimmunoprecipitation 16782902 physical association X 2 P19878 Q15080 coimmunoprecipitation 9064349 - X 2

PPI - HINT Gene A Gene B PMID Method Quality NCF1 NCF4 11258927,11796733 0096,0096 LC NCF2 NCF4 11483497,9490029,11796733,16297854,11893732,11483497,11893732,16782902,12813044,12813044,11796733,16782902,12813044,9490029,9490029,11893732,8760383 0018,0004,0018,0006,0018,0096,0004,0004,0004,0018,0096,0007,0007,0018,0049,0401,0007 LC NCF1 NCF4 11258927,11796733 0096,0096 LC NCF2 NCF4 11483497,9490029,11796733,16297854,11893732,11483497,11893732,16782902,12813044,12813044,11796733,16782902,12813044,9490029,9490029,11893732,8760383 0018,0004,0018,0006,0018,0096,0004,0004,0004,0018,0096,0007,0007,0018,0049,0401,0007 LC TXN NCF4 10397171 0018 LC XRCC6 NCF4 9914162,9914162 0018,0096 LC CYBA NCF4 17803994 0047 LC NCF1 NCF4 15657040,15657040,9083043 0017,0114,0018 LC NCF2 NCF4 11483497,10486263,9490029,11796733,11893732,11483497,10672014,11893732,9083043,12813044,12813044,9064349,11796733,12887891,12813044,9490029,9490029,11893732 0018,0018,0004,0018,0018,0096,0018,0004,0018,0004,0018,0019,0096,0114,0007,0018,0049,0401 LC MLH1 NCF4 20706999 0018 LC PRKDC NCF4 9914162 0415 LC NCF4 NCF4 17290225,15657040 0114,0114 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q5NIP6 Q15080 GATA NCF4 0.126 20711500 Q15080 P10599 NCF4 TXN 0.309 10397171 Q15080 P12956 NCF4 XRCC6 0.523 9914162 Q15080 P14598 NCF4 NCF1 0.843 15657040,11258927,9083043,11796733 Q15080 P26038 NCF4 MSN 0.454 11716484 Q15080 P19878 NCF4 NCF2 0.99 9490029,16297854,9083043,11893732,11796733,16782902,12813044,12887891,11483497 Q15080 P40692 NCF4 MLH1 0.332 20706999 Q15080 P78527 NCF4 PRKDC 0.309 9914162 Q15080 P13498 NCF4 CYBA 0.309 17803994