Drug & target - TTD Name Type of Target Synonyms Disease Drugs Inhibitor Antibody mRNA of Inhibitor of apoptosis protein Clinical trial target XIAP;X-linked IAP;X-linked inhibitor of apoptosis;X-linked inhibitor of apoptosis protein;Baculoviral IAP repeat-containing protein 4;HILP;IAP-like protein;Inhibitor of apoptosis protein 3 Ovarian cancer;Obesity;Hepatocellular carcinoma;Neoplasms AEG35156;GDC-0152 SM-131;ARPFAQK-FAM;EMBELIN;SM-122;BV-6;SM-337;AVPIAQKSEK-FAM X-linked inhibitor of apoptosis protein Clinical trial target E3 ubiquitinprotein ligase XIAP;Baculoviral IAP repeatcontaining protein 4;IAPlike protein;ILP;hILP;Inhibitor of apoptosis protein 3;IAP3;hIAP3;Xlinked IAP Hematological malignancies;Huntington's disease;Lymphoma;Retinopathy;Cancer HGS-1029;TL-32711;Debio 1143;Birinapant TL-32711;Debio 1143;Birinapant

Drug & target - GRAC X-linked inhibitor of apoptosis other_protein 889 Inhibitors of apoptosis (IAP) protein family 2790 Xq25

Drug & target - Manually collected Targeting Agent Target Stage Reference PMID GDC-0152; LCL-161; TL32711; HGS1029; AT-406 IAP phase I/II 22413863; 26919436 AEG-35156 XIAP phase II 24977690; 26919436 SM-406 IAP pre-clinical 21443232; 23813446