PTM - CPLM Gene Name UniProt ID Type Position Code WDR59; KIAA1923; FP977 Q6PJI9 Ubiquitination 863 K WDR59; KIAA1923; FP977 Q6PJI9 Ubiquitination 226 K WDR59; KIAA1923; FP977 Q6PJI9 Ubiquitination 646 K WDR59; KIAA1923; FP977 Q6PJI9 Ubiquitination 298 K WDR59; KIAA1923; FP977 Q6PJI9 Ubiquitination 466 K WDR59; KIAA1923; FP977 Q6PJI9 Ubiquitination 864 K WDR59; KIAA1923; FP977 Q6PJI9 Ubiquitination 159 K WDR59; KIAA1923; FP977 Q6PJI9 Ubiquitination 140 K WDR59; KIAA1923; FP977 Q6PJI9 Ubiquitination 609 K WDR59; KIAA1923; FP977 Q6PJI9 Ubiquitination 679 K WDR59; KIAA1923; FP977 Q6PJI9 Ubiquitination 588 K WDR59; KIAA1923; FP977 Q6PJI9 Ubiquitination 91 K WDR59; KIAA1923; FP977 Q6PJI9 Ubiquitination 239 K WDR59; KIAA1923; FP977 Q6PJI9 Ubiquitination 381 K WDR59; KIAA1923; FP977 Q6PJI9 Ubiquitination 894 K

PTM - dbPAF Gene Name UniProt ID Position Type Species WDR59; KIAA1923; FP977 Q6PJI9 181 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 182 T Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 564 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 577 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 600 Y Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 601 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 603 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 605 T Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 607 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 624 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 629 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 772 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 778 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 780 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 782 Y Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 784 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 786 T Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 787 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 788 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 790 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 792 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 793 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 795 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 816 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 821 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 822 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 830 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 832 T Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 833 Y Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 834 S Homo sapiens(Human) WDR59; KIAA1923; FP977 Q6PJI9 887 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q6PJI9 K863-ac Acetylation TQQFDDFkkCYGEIL Q6PJI9 T142-p Phosphorylation IKDTRKPtVALsAVA Q6PJI9 S146-p Phosphorylation RKPtVALsAVAGASQ Q6PJI9 S181-p Phosphorylation IWDKRKPsTAVEYLA Q6PJI9 S564-p Phosphorylation MTMHRAVsPtEPTPR Q6PJI9 T566-p Phosphorylation MHRAVsPtEPTPRSL Q6PJI9 S577-p Phosphorylation PRSLSALsAYHTGLI Q6PJI9 S603-p Phosphorylation NLRLYSGsPtRsEKE Q6PJI9 T605-p Phosphorylation RLYSGsPtRsEKEQV Q6PJI9 S607-p Phosphorylation YSGsPtRsEKEQVSI Q6PJI9 S624-p Phosphorylation FYYKERKsRRWKsKR Q6PJI9 S629-p Phosphorylation RKsRRWKsKREGSDS Q6PJI9 S772-p Phosphorylation FGPFPNRssNLVVsH Q6PJI9 S773-p Phosphorylation GPFPNRssNLVVsHs Q6PJI9 S778-p Phosphorylation RssNLVVsHsRyPsF Q6PJI9 S780-p Phosphorylation sNLVVsHsRyPsFts Q6PJI9 Y782-p Phosphorylation LVVsHsRyPsFtssG Q6PJI9 S784-p Phosphorylation VsHsRyPsFtssGsC Q6PJI9 T786-p Phosphorylation HsRyPsFtssGsCss Q6PJI9 S787-p Phosphorylation sRyPsFtssGsCssM Q6PJI9 S788-p Phosphorylation RyPsFtssGsCssMs Q6PJI9 S790-p Phosphorylation PsFtssGsCssMsDP Q6PJI9 S792-p Phosphorylation FtssGsCssMsDPGL Q6PJI9 S793-p Phosphorylation tssGsCssMsDPGLN Q6PJI9 S795-p Phosphorylation sGsCssMsDPGLNTG Q6PJI9 S821-p Phosphorylation LSSPWGEssPEELRF Q6PJI9 S822-p Phosphorylation SSPWGEssPEELRFG Q6PJI9 S830-p Phosphorylation PEELRFGsLtysDPR Q6PJI9 T832-p Phosphorylation ELRFGsLtysDPRER Q6PJI9 Y833-p Phosphorylation LRFGsLtysDPRERE Q6PJI9 S834-p Phosphorylation RFGsLtysDPRERER Q6PJI9 S887-p Phosphorylation AEVLKFVsCPPDPHk Q6PJI9 K159-ub Ubiquitination SQVKWNKkNANCLAT Q6PJI9 K226-ub Ubiquitination WDYRQPRkYLNILPC Q6PJI9 K381-ub Ubiquitination RNLLEERkSDQLGLP Q6PJI9 K863-ub Ubiquitination TQQFDDFkkCYGEIL Q6PJI9 K864-ub Ubiquitination QQFDDFkkCYGEILY Q6PJI9 K894-ub Ubiquitination sCPPDPHkGIEFGVY

PTM - dbPTM UniProt ID Position Code Type Resources References Q6PJI9 564 S Phosphorylation Swiss-Prot 1010711 19413330 Q6PJI9 821 S Phosphorylation Swiss-Prot 1010711 18669648 Q6PJI9 822 S Phosphorylation Swiss-Prot 1010711 18669648 Q6PJI9 830 S Phosphorylation Swiss-Prot 1010711 19690332 Q6PJI9 821 S Phosphorylation PhosphoELM.10011 18669648 Q6PJI9 822 S Phosphorylation PhosphoELM.10011 18669648 Q6PJI9 381 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6PJI9 863 K Ubiquitylation Phosphositeplus.1010730 21906983 Q6PJI9 564 S Phosphorylation Phosphositeplus.1010730 19664994;22115753 Q6PJI9 603 S Phosphorylation Phosphositeplus.1010730 20068231;22115753 Q6PJI9 607 S Phosphorylation Phosphositeplus.1010730 20068231 Q6PJI9 821 S Phosphorylation Phosphositeplus.1010730 18669648;21406692 Q6PJI9 822 S Phosphorylation Phosphositeplus.1010730 18669648;19690332;21406692 Q6PJI9 830 S Phosphorylation Phosphositeplus.1010730 19690332 Q6PJI9 564 S Phosphorylation HPRD 9.0 19413330,19664994 Q6PJI9 601 S Phosphorylation HPRD 9.0 20068231 Q6PJI9 603 S Phosphorylation HPRD 9.0 20068231 Q6PJI9 607 S Phosphorylation HPRD 9.0 20068231 Q6PJI9 821 S Phosphorylation HPRD 9.0 18669648,20068231 Q6PJI9 822 S Phosphorylation HPRD 9.0 18669648 Q6PJI9 600 Y Phosphorylation HPRD 9.0 20068231 Q6PJI9 821 S Phosphorylation SysPTM 1.1 18669648 Q6PJI9 822 S Phosphorylation SysPTM 1.1 18669648

PTM - HPRD Symbol Position Code Type References WDR59 564 S Phosphorylation 19413330,19664994 WDR59 600 Y Phosphorylation 20068231 WDR59 601 S Phosphorylation 20068231 WDR59 603 S Phosphorylation 20068231 WDR59 607 S Phosphorylation 20068231 WDR59 821 S Phosphorylation 18669648,20068231 WDR59 822 S Phosphorylation 18669648

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q6PJI9 821 S 18669648 HTP Phosphorylation Q6PJI9 822 S 18669648 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q6PJI9 564 Phosphoserine 23186163;24275569 Q6PJI9 821 Phosphoserine 18669648 Q6PJI9 822 Phosphoserine 18669648;23186163 Q6PJI9 830 Phosphoserine 23186163

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type WDR59 IPI00242841 S 603 LRLYSGpSPTRSEK phosphorylation WDR59 IPI00242841 S 607 SGSPTRpSEKEQVS phosphorylation WDR59 IPI00242841 Y 600 PGNLRLpYSGSPTR phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 79726 122841 - K Ubiquitination 21139048 79726 122841 - K Ubiquitination 21906983 79726 122841 - K Ubiquitination 22505724

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID WDR59 Homo sapiens (Human) 308 "308,QQFDDFKKCYGEI" 308:21906983 WDR59 Homo sapiens (Human) 455 "455,QQFDDFKKCYGEI" 455:21906983 WDR59 Homo sapiens (Human) 381 "381,NLLEERKSDQLGL" 381:21906983 WDR59 Homo sapiens (Human) 381; 863 "381,NLLEERKSDQLGL; 863,QQFDDFKKCYGEI" 381:21906983; 863:21906983