PTM - CPLM Gene Name UniProt ID Type Position Code DMXL2; KIAA0856 Q8TDJ6 Acetylation 1049 K DMXL2; KIAA0856 Q8TDJ6 Ubiquitination 1876 K DMXL2; KIAA0856 Q8TDJ6 Ubiquitination 2591 K DMXL2; KIAA0856 Q8TDJ6 Ubiquitination 1907 K

PTM - dbPAF Gene Name UniProt ID Position Type Species DMXL2; KIAA0856 Q8TDJ6 1077 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1140 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1143 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1151 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1221 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1251 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1287 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1288 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1299 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1300 T Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1398 T Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1400 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1402 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1404 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1405 T Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1409 T Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1456 Y Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1468 Y Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1515 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1516 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1521 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1857 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1861 T Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1915 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1918 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1960 Y Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 198 Y Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 1984 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 2062 Y Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 2074 Y Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 2101 T Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 2102 Y Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 2103 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 2197 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 2235 Y Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 2330 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 2331 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 2399 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 2434 T Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 246 Y Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 2717 Y Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 2753 T Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 2777 Y Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 451 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 463 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 473 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 585 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 588 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 614 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 743 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 925 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 929 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 930 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 944 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 945 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 948 T Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 949 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 951 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 960 S Homo sapiens(Human) DMXL2; KIAA0856 Q8TDJ6 966 T Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q8TDJ6 K1049-ac Acetylation EKEIYHWkRWPLMND Q8TDJ6 K1876-ac Acetylation TEKNFVDkINLIERK Q8TDJ6 K2602-m1 Methylation EPENTPFkSRDSSAF Q8TDJ6 Y198-p Phosphorylation DCLLKVWyPMTGWKS Q8TDJ6 Y246-p Phosphorylation SWRKTSKyMPRGSVC Q8TDJ6 S325-p Phosphorylation LRKGQRRsSVLVTHA Q8TDJ6 S434-p Phosphorylation DREDEEHsQEDRERG Q8TDJ6 S451-p Phosphorylation MKLDHDLsLDRESEA Q8TDJ6 S473-p Phosphorylation EDGEREGsPRTYSRL Q8TDJ6 S481-p Phosphorylation PRTYSRLsVPMPLPT Q8TDJ6 S588-p Phosphorylation QEGMSVGsPHGSQPH Q8TDJ6 S685-p Phosphorylation ELDCQWDsDNKLSRL Q8TDJ6 S743-p Phosphorylation LSYTGGVsELARINS Q8TDJ6 S925-p Phosphorylation QACLAKAsEGAssEs Q8TDJ6 S929-p Phosphorylation AKAsEGAssEsLLSV Q8TDJ6 S930-p Phosphorylation KAsEGAssEsLLSVP Q8TDJ6 S932-p Phosphorylation sEGAssEsLLSVPGQ Q8TDJ6 S944-p Phosphorylation PGQKNVDssPETsPS Q8TDJ6 S945-p Phosphorylation GQKNVDssPETsPSV Q8TDJ6 S949-p Phosphorylation VDssPETsPSVSPMP Q8TDJ6 S960-p Phosphorylation SPMPHSSsIANLQtA Q8TDJ6 T966-p Phosphorylation SsIANLQtASKLILS Q8TDJ6 S1140-p Phosphorylation SVLDSRVsVDsNLFV Q8TDJ6 S1143-p Phosphorylation DSRVsVDsNLFVYSK Q8TDJ6 S1151-p Phosphorylation NLFVYSKsDALLSKD Q8TDJ6 S1251-p Phosphorylation GTPSLPVsLSWVRDG Q8TDJ6 S1299-p Phosphorylation EAAMQDHstFKSNML Q8TDJ6 T1300-p Phosphorylation AAMQDHstFKSNMLA Q8TDJ6 T1398-p Phosphorylation TKRHLSRtIsVsGsT Q8TDJ6 S1400-p Phosphorylation RHLSRtIsVsGsTAK Q8TDJ6 S1402-p Phosphorylation LSRtIsVsGsTAKET Q8TDJ6 S1404-p Phosphorylation RtIsVsGsTAKETVT Q8TDJ6 Y1456-p Phosphorylation STKIPQSyEDQTVSQ Q8TDJ6 Y1468-p Phosphorylation VSQPEDQySELFQIQ Q8TDJ6 S1515-p Phosphorylation QEHARVLssHLMHsS Q8TDJ6 S1516-p Phosphorylation EHARVLssHLMHsSL Q8TDJ6 S1521-p Phosphorylation LssHLMHsSLPGLTR Q8TDJ6 S1857-p Phosphorylation LIRRNLAsPEGtLAT Q8TDJ6 T1861-p Phosphorylation NLAsPEGtLATLGLK Q8TDJ6 Y1960-p Phosphorylation SNVTSSQyDWSQPIV Q8TDJ6 S1984-p Phosphorylation DWGEDHDsALDEEED Q8TDJ6 Y2062-p Phosphorylation LRTLATGyEVDGGKL Q8TDJ6 T2101-p Phosphorylation IKEYSSKtysKVESD Q8TDJ6 Y2102-p Phosphorylation KEYSSKtysKVESDL Q8TDJ6 S2103-p Phosphorylation EYSSKtysKVESDLL Q8TDJ6 S2123-p Phosphorylation VDKPDIGsYERHQIE Q8TDJ6 S2197-p Phosphorylation TTVKQLQsPLPLPTT Q8TDJ6 S2330-p Phosphorylation SSLINLLssAQDEDQ Q8TDJ6 S2331-p Phosphorylation SLINLLssAQDEDQP Q8TDJ6 S2399-p Phosphorylation VVKPRRQsENISAPP Q8TDJ6 T2434-p Phosphorylation GRPVKDAtPPPVPAE Q8TDJ6 Y2717-p Phosphorylation KSSDDVDyRGSTTTL Q8TDJ6 Y2777-p Phosphorylation TSHPVHQyYLTGAQD Q8TDJ6 K1876-ub Ubiquitination TEKNFVDkINLIERK Q8TDJ6 K1907-ub Ubiquitination LALEVLSkIPKVTKT

PTM - dbPTM UniProt ID Position Code Type Resources References Q8TDJ6 944 S Phosphorylation Swiss-Prot 1010711 18669648;19690332 Q8TDJ6 945 S Phosphorylation Swiss-Prot 1010711 18669648;19690332 Q8TDJ6 949 S Phosphorylation Swiss-Prot 1010711 18669648 Q8TDJ6 1049 K Acetylation Swiss-Prot 1010711 19608861 Q8TDJ6 1140 S Phosphorylation Swiss-Prot 1010711 19690332 Q8TDJ6 1143 S Phosphorylation Swiss-Prot 1010711 19690332 Q8TDJ6 1400 S Phosphorylation Swiss-Prot 1010711 15144186;18669648 Q8TDJ6 1404 S Phosphorylation Swiss-Prot 1010711 15144186 Q8TDJ6 1857 S Phosphorylation Swiss-Prot 1010711 18669648;18691976;19690332 Q8TDJ6 1984 S Phosphorylation Swiss-Prot 1010711 18669648;19690332 Q8TDJ6 944 S Phosphorylation PhosphoELM.10011 18669648 Q8TDJ6 945 S Phosphorylation PhosphoELM.10011 18669648 Q8TDJ6 949 S Phosphorylation PhosphoELM.10011 18669648 Q8TDJ6 1400 S Phosphorylation PhosphoELM.10011 18669648;15144186 Q8TDJ6 1404 S Phosphorylation PhosphoELM.10011 15144186 Q8TDJ6 1857 S Phosphorylation PhosphoELM.10011 18669648 Q8TDJ6 1984 S Phosphorylation PhosphoELM.10011 18669648 Q8TDJ6 948 T Phosphorylation PhosphoELM.10011 18669648 Q8TDJ6 1049 K Acetylation Phosphositeplus.1010730 19608861 Q8TDJ6 1140 S Phosphorylation Phosphositeplus.1010730 19690332;20393185;21659604 Q8TDJ6 1143 S Phosphorylation Phosphositeplus.1010730 19690332;20393185;21659604 Q8TDJ6 1400 S Phosphorylation Phosphositeplus.1010730 14729942;15144186;18669648 Q8TDJ6 1404 S Phosphorylation Phosphositeplus.1010730 14729942;15144186 Q8TDJ6 1857 S Phosphorylation Phosphositeplus.1010730 18669648;18691976;19690332;20068231;20886841;21659604 Q8TDJ6 1984 S Phosphorylation Phosphositeplus.1010730 18669648;19690332;22115753 Q8TDJ6 473 S Phosphorylation Phosphositeplus.1010730 21659604 Q8TDJ6 588 S Phosphorylation Phosphositeplus.1010730 20068231 Q8TDJ6 929 S Phosphorylation Phosphositeplus.1010730 20058876 Q8TDJ6 944 S Phosphorylation Phosphositeplus.1010730 18669648;19690332;20363803;22115753 Q8TDJ6 945 S Phosphorylation Phosphositeplus.1010730 18669648;19690332;20363803;22115753 Q8TDJ6 949 S Phosphorylation Phosphositeplus.1010730 18669648 Q8TDJ6 1049 K Acetylation HPRD 9.0 19608861 Q8TDJ6 585 S Phosphorylation HPRD 9.0 20068231 Q8TDJ6 588 S Phosphorylation HPRD 9.0 20068231 Q8TDJ6 929 S Phosphorylation HPRD 9.0 20058876 Q8TDJ6 944 S Phosphorylation HPRD 9.0 18669648 Q8TDJ6 945 S Phosphorylation HPRD 9.0 18669648 Q8TDJ6 949 S Phosphorylation HPRD 9.0 18669648 Q8TDJ6 1400 S Phosphorylation HPRD 9.0 15144186,18669648 Q8TDJ6 1404 S Phosphorylation HPRD 9.0 15144186 Q8TDJ6 1857 S Phosphorylation HPRD 9.0 18669648,18691976,20068231 Q8TDJ6 1984 S Phosphorylation HPRD 9.0 18669648 Q8TDJ6 948 T Phosphorylation HPRD 9.0 18669648 Q8TDJ6 944 S Phosphorylation SysPTM 1.1 18669648 Q8TDJ6 945 S Phosphorylation SysPTM 1.1 18669648 Q8TDJ6 949 S Phosphorylation SysPTM 1.1 18669648 Q8TDJ6 1400 S Phosphorylation SysPTM 1.1 18669648 Q8TDJ6 1857 S Phosphorylation SysPTM 1.1 18691976;18669648 Q8TDJ6 1984 S Phosphorylation SysPTM 1.1 18669648

PTM - HPRD Symbol Position Code Type References DMXL2 1049 K Acetylation 19608861 DMXL2 1400 S Phosphorylation 15144186,18669648 DMXL2 1404 S Phosphorylation 15144186 DMXL2 1857 S Phosphorylation 18669648,18691976,20068231 DMXL2 1984 S Phosphorylation 18669648 DMXL2 585 S Phosphorylation 20068231 DMXL2 588 S Phosphorylation 20068231 DMXL2 929 S Phosphorylation 20058876 DMXL2 944 S Phosphorylation 18669648 DMXL2 945 S Phosphorylation 18669648 DMXL2 948 T Phosphorylation 18669648 DMXL2 949 S Phosphorylation 18669648

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q8TDJ6 944 S 18669648 HTP Phosphorylation Q8TDJ6 1857 S 18669648 HTP Phosphorylation Q8TDJ6 1984 S 18669648 HTP Phosphorylation Q8TDJ6 949 S 18669648 HTP Phosphorylation Q8TDJ6 948 T 18669648 HTP Phosphorylation Q8TDJ6 945 S 18669648 HTP Phosphorylation Q8TDJ6 1400 S 18669648 HTP Phosphorylation Q8TDJ6 1400 S 15144186 HTP Phosphorylation Q8TDJ6 1404 S 15144186 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q8TDJ6 473 Phosphoserine 23186163 Q8TDJ6 944 Phosphoserine 18669648;19690332 Q8TDJ6 945 Phosphoserine 18669648;19690332 Q8TDJ6 1140 Phosphoserine 19690332 Q8TDJ6 1143 Phosphoserine 19690332 Q8TDJ6 1151 Phosphoserine 23186163 Q8TDJ6 1400 Phosphoserine 18669648 Q8TDJ6 1857 Phosphoserine 18669648;18691976;20068231;23186163 Q8TDJ6 1984 Phosphoserine 19690332 Q8TDJ6 2399 Phosphoserine 23186163

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type DMXL2 IPI00152542 K 1049 KEIYHWaKRWPLMN acetylation DMXL2 IPI00152542 S 1077 PVAVSCpSYTGRLA phosphorylation DMXL2 IPI00152542 S 1857 IRRNLApSPEGTLA phosphorylation DMXL2 IPI00152542 S 743 SYTGGVpSELARIN phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 23312 116903 - K Ubiquitination 21139048 23312 116903 - K Ubiquitination 24816145