PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus EIF5 TBCB 22863883 biogrid exp GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G ISOC1 TBCB 22863883 biogrid exp G G G G GP GP G G GP G G G G GP G GP GP G GP G GP G G G GP G GP G G ANXA6 TBCB 26344197 biogrid exp GP G G G GP GP G G GP G GP GP G GP G G GP GP GP G GP GP G G G G G GP G CSE1L TBCB 22863883 biogrid exp GP G G G G G G G GP G G G G GP G G G G G G GP G G G G G GP GP G PTMA TBCB 22863883 biogrid exp GP G G G GP GP G G GP G GP GP G GP G GP GP G GP G GP GP G G GP G GP GP G CKB TBCB 22863883 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G G GP G G G G GP G G TBCB AARSD1 26344197 biogrid exp P P P P P P P P P P P P P P P P NTRK1 TBCB 25921289 biogrid exp P P G P P P P P P P P P P P P ASNS TBCB 22863883 biogrid exp GP G G G GP GP G G GP G G G GP G G GP G GP G P G G G G G GP GP G TBCB STK24 22863883 biogrid exp GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G OGFOD1 TBCB 22863883 biogrid exp GP G G G GP GP G G GP G GP G G GP G GP GP GP GP G GP G G G GP G GP GP G PPP1CA TBCB 22863883 biogrid exp GP G G G GP GP G G GP G GP G G GP G GP GP G GP G GP GP G G GP G GP GP G PLBD2 TBCB 26344197 biogrid exp P G P GP G G P G P GP P GP G GP G P P G G P P GP HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BI TBCB 25281560 biogrid exp GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G D2HGDH TBCB 26344197 biogrid exp G G G G G GP G G G G GP G G G G GP GP G G G GP G G G GP G G GP G GSS TBCB 22863883 biogrid exp GP G G G GP GP G G GP G GP GP G GP G GP GP G GP G GP GP G G GP G GP GP G PDIA4 TBCB 22863883 biogrid exp GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G TBCB SCPEP1 22863883 biogrid exp G G G G G GP G G GP G GP GP G GP G GP GP G GP G GP GP G G GP G GP GP G TBCB STK26 22863883 biogrid exp GP G G P GP G G G G G GP P P G G GP G GP G GP P G LGSN TBCB 26344197 biogrid exp P P P P P GP P P P P GP P P P P UBFD1 TBCB 22863883 biogrid exp GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G TPT1 TBCB 22939629 biogrid exp GP G G G GP GP G G GP G GP G G GP G GP GP GP GP G GP GP G G GP G GP GP G HK2 TBCB 26344197 biogrid exp GP G G G GP GP G G GP G P G GP G GP GP G GP GP GP G G GP G GP GP G TBCB XPNPEP1 26344197 biogrid exp G G G G G GP G G GP G GP GP G G G GP GP GP GP G GP GP G G GP G GP GP G IFI16 TBCB 25665578 intact exp G G G G GP GP G G GP G GP G G GP G G GP GP G G G G G G G G G G G ALDH7A1 TBCB 22863883 biogrid exp GP G G G G GP G G GP G GP GP G G G G GP GP GP G GP GP G G G G GP GP G SNRPF TBCB 22863883 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TWF2 TBCB 22863883 biogrid exp G G G G G G G G G G G G G GP G G G G G G G G G G G G GP GP G VCL TBCB 22863883 biogrid exp GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G PPP1R14B TBCB 26344197 biogrid exp GP G G G G GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G TBCB ERP44 22863883 biogrid exp GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G ELAVL1 TBCB 19322201 biogrid exp GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G FERMT2 TBCB 22863883 biogrid exp GP G G G G GP G G GP G GP GP G GP G GP GP G GP G GP GP G G GP G GP GP G PAK1 TBCB 17389360 dip exp GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G TXNDC5 TBCB 22939629 biogrid exp P P P P P P P OTUB1 TBCB unassigned1260 intact exp GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G PROSC TBCB 22863883 biogrid exp GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G YWHAE TBCB 22863883 biogrid exp, ortho GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G YWHAH TBCB 22863883 biogrid exp, ortho GP G G G GP GP G G GP G GP GP G G G GP GP GP GP G GP GP G G GP G GP GP G MAPRE1 TBCB 22863883, 21836163 biogrid exp, pred GP G G G G GP G G GP G GP G G GP G GP GP GP GP G GP GP G G GP G GP GP G TBCB GAN 16303566, 21836163 hprd,biogrid,intact exp, pred P P P P P P P P P P P P P P USP7 TBCB 16713569, 25402006 hprd,biogrid,mint,intact exp, pred GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G TUBA4A TBCB 9265649, 16082366 hprd exp, pred GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G MYO1E TBCB 22863883, 23023127 biogrid exp, pred GP G GP GP G G GP G GP GP G GP G GP GP G GP G GP GP G G GP G GP GP G CAPNS1 TBCB 22863883, 25402006 biogrid exp, pred GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G PSMC2 TBCB ortho GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G TSPO TBCB ortho GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G CNBP TBCB ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CCT5 TBCB 16082366 ortho, pred G G G G GP GP G G GP G GP G G GP G GP GP GP GP G GP GP G G GP G GP GP G TBCB TUBA1C 16082366 ortho, pred GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G KATNA1 TBCB 21836163 pred GP G G G GP GP G G GP G GP GP G GP G GP GP G GP G GP G G G GP G GP GP G DCTN1 TBCB 25402006, 23023127 pred GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G CLASP1 TBCB 21836163 pred GP G G G G GP G G GP G GP GP G G G GP GP G GP G GP GP G G GP G GP GP G TBCB TBCD 21836163 pred G G G G G GP G G GP G GP GP G G G GP GP G G G GP G G G GP G GP GP G TBCB ARL8B 21836163 pred GP G G G GP GP G G GP G GP GP G GP G GP GP G GP G GP GP G G GP G GP GP G TBCB MAPRE3 21836163 pred P G GP G G P G P GP GP GP G GP P G P GP TBCC TBCB 21836163 pred GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G TBCB SNX15 21836163 pred GP G G G GP GP G G GP G GP G G GP G GP GP G GP G GP GP G G GP G GP GP G CKAP5 TBCB 21836163 pred GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G TUBA1B TBCB 16082366 pred GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G PPP2R1A TBCB 21836163 pred GP G G G G GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G TAOK1 TBCB 21836163 pred GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G ARL8A TBCB 21836163 pred GP G G G GP GP G G GP G GP GP G G G GP GP G GP G GP GP G G GP G GP GP G HMGN2 TBCB 16082366 pred GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G MAP1B TBCB 25402006 pred G G G G G GP G G GP G GP G G G G G GP G GP G GP GP G G G G G GP G SET TBCB 21836163 pred GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G POLR2I TBCB 25402006 pred GP G G G GP GP G G GP G GP GP G G G GP GP GP GP G GP GP G G GP G GP GP G TP53 TBCB 25402006 pred G G G G G G G G G G G G G G G GP G G G G GP G G G GP G G GP G BIN1 TBCB 23023127 pred GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G CLIP3 TBCB 21836163 pred GP G G P GP G G GP G GP G GP G GP GP GP GP G P G GP G GP GP G PSMD8 TBCB 25402006 pred GP G G G G GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G TBCB TRAF6 25402006 pred GP G G G GP G G G GP G GP GP G G G GP G GP G G GP GP G G GP G GP GP G AP2M1 TBCB 21836163 pred GP G G G G GP G G GP G GP GP G GP G GP GP G GP G GP G G G GP G GP GP G RNF220 TBCB 25402006 pred G G G G GP GP G G GP G GP GP G G G G GP G GP G GP GP G G G G GP G G USP11 TBCB 25402006 pred G G G G G GP G G GP G GP G G G G G GP G G G G G G G G G G GP G NME9 TBCB 21836163 pred GP G G G GP GP G G GP G GP GP G P G GP GP GP G GP P G G GP G GP GP G CLASP2 TBCB 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G TBCB TUBA8 16082366 pred P G GP P GP P P P P P P GP P P G P P P FIBP TBCB 25402006 pred GP G G G GP GP G G GP G GP GP G GP G GP GP G GP G GP GP G G GP G GP GP G UBA1 TBCB 25402006 pred GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G TUBA1A TBCB 25402006, 21836163, 16082366 pred GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G RAE1 TBCB 25402006 pred GP G G G GP GP G G GP G GP G G GP G GP GP GP GP G GP G G G GP G GP GP G TBCB 16082366 pred ERP29 TBCB 21836163 pred GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G MAP7 TBCB 21836163 pred GP G G P GP GP G GP GP G P G GP GP GP G GP GP G GP GP GP MDM4 TBCB 25402006 pred GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G GDI1 TBCB 25402006 pred GP G G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G GMPS TBCB 25402006 pred G G G G GP GP G G G G G G G G G G GP G G G G G G G G G G GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P55060 Q99426 biochemical 22863883 colocalization X 2 P62306 Q99426 biochemical 22863883 colocalization X 2 Q99426 Q93009 two hybrid 16713569 direct interaction X 2 Q99426 Q93009 affinity chromatography technology 16713569 physical association X 2 Q99426 Q8NBS9 biochemical 22939629 colocalization X 2 Q99426 P49419-3 biochemical 22863883 colocalization X 2 Q99426 P12277 biochemical 22863883 colocalization X 2 Q99426 A0A090N8Y2 biochemical 22863883 colocalization X 2 Q99426 Q9BS26 biochemical 22863883 colocalization X 2 Q99426 P48637 biochemical 22863883 colocalization X 2 Q99426 Q12965 biochemical 22863883 colocalization X 2 Q99426 Q6IBS0 biochemical 22863883 colocalization X 2 Q99426 O14562 biochemical 22863883 colocalization X 2 Q99426 A0A024R1K7 biochemical 22863883 colocalization X 2 P13693 Q99426 biochemical 22939629 colocalization X 2 Q15691 Q99426 biochemical 22863883 colocalization X 2 Q9HB40 Q99426 biochemical 22863883 colocalization X 2 Q8N543 Q99426 biochemical 22863883 colocalization X 2 P0CG48 Q99426 affinity chromatography technology 16303566 physical association X 2 P0CG48 Q99426 affinity chromatography technology 22053931 physical association X 2 P0CG48 Q99426 affinity chromatography technology 23000965 physical association X 2 P0CG48 Q99426 affinity chromatography technology 24816145 physical association X 2 P0CG48 Q99426 affinity chromatography technology 21139048 physical association X 2 P0CG48 Q99426 affinity chromatography technology 21890473 physical association X 2 P0CG48 Q99426 affinity chromatography technology 21906983 physical association X 2 Q99426 Q9H2C0 two hybrid 16303566 direct interaction X 2 Q99426 Q9H2C0 affinity chromatography technology 16303566 physical association X 2 Q99426 Q9H2C0 affinity chromatography technology 16303566 physical association X 2 Q99426 P08243-3 biochemical 22863883 colocalization X 2 Q99426 P04632 biochemical 22863883 colocalization X 2 Q99426 Q96CN7 biochemical 22863883 colocalization X 2 Q99426 P62136-3 biochemical 22863883 colocalization X 2 Q99426 O94903 biochemical 22863883 colocalization X 2 Q99426 Q5U0E6 biochemical 22863883 colocalization X 2 Q99426 A0A024R6Q1 biochemical 22863883 colocalization X 2 Q99426 biochemical 22863883 colocalization X 2 Q99426 Q9P289-2 biochemical 22863883 colocalization X 2 Q99426 P06454 biochemical 22863883 colocalization X 2 Q99426 biochemical 22863883 colocalization X 2 Q99426 P62258 biochemical 22863883 colocalization X 2 Q99426 P61956-2 affinity chromatography technology 25027693 physical association X 2 Q99426 A0A024R5P0 two hybrid 17389360 physical association X 2 P68366 Q99426 in vitro 9265649 - X 2 P68366 Q99426 in vitro 9265649 - X 2 Q99426 Q93009 two hybrid 16713569 - X 2 Q99426 Q93009 two hybrid 16713569 - X 2 Q99426 Q9H2C0 in vivo 16303566 - X 2 Q99426 Q9H2C0 two hybrid 16303566 - X 2 Q99426 Q9H2C0 in vivo 16303566 - X 2 Q99426 Q9H2C0 two hybrid 16303566 - X 2 Q99426 Q93009 two hybrid array 16713569 physical association X 2 Q99426 Q93009 pull down 16713569 physical association X 2 Q99426 Q9H2C0 anti tag coimmunoprecipitation 16303566 physical association X 2 Q99426 Q9H2C0 anti tag coimmunoprecipitation 16303566 physical association X 2 Q99426 Q9H2C0 two hybrid 16303566 physical association X 2 Q81K51 Q99426 two hybrid pooling approach 20711500 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B SNRPF TBCB MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304058 prey bait ISOC1 TBCB MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_300667 prey bait TUBA4A TBCB MI:0492(in vitro) 9265649 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_4372 - - FERMT2 TBCB MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304287 bait prey UBFD1 TBCB MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304787 prey bait OGFOD1 TBCB MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304291 bait prey TBCB SCPEP1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_303800 bait prey CKB TBCB MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_299008 prey bait PROSC TBCB MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_302298 prey bait MAPRE1 TBCB MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_301027 prey bait YWHAH TBCB MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_305192 prey bait TBCB GAN MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0493(in vivo)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 16303566 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|MI:0468(hprd)|(intact)|(intact)|(intact) BIOGRID_199148|BIOGRID_199147|BIOGRID_199146|HPRD_32560|UniProt_82094|UniProt_82096|UniProt_82095 bait|prey|prey|-|prey|prey|bait prey|bait|bait|-|bait|bait|prey USP7 TBCB MI:0018(two hybrid)|MI:0096(pull down)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0397(two hybrid array)|MI:0096(pull down)|MI:0397(two hybrid array) 16713569 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|MI:0471(mint)|(biogrid)|MI:0468(hprd)|MI:0471(mint)|(intact)|MI:0471(mint)|(intact) BIOGRID_215991|MINT_82376|MINT_50088|BIOGRID_215418|HPRD_334|MINT_82301|UniProt_85834|MINT_50013|UniProt_86556 bait|bait|bait|bait|-|bait|prey|bait|unspecified role prey|prey|prey|prey|-|prey|bait|prey|unspecified role ELAVL1 TBCB MI:0096(pull down) 19322201 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_187502 bait prey UBC TBCB MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16303566,21139048,21890473,21906983,22053931,23000965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_168447|BIOGRID_199149|BIOGRID_222139|BIOGRID_177821|BIOGRID_174403|BIOGRID_268900 bait|prey|bait|bait|bait|bait prey|bait|prey|prey|prey|prey ALDH7A1 TBCB MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_298397 prey bait CAPNS1 TBCB MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_298888 prey bait CSE1L TBCB MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304284 bait prey TBCB STK24 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304182 bait prey EIF5 TBCB MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304285 bait prey GSS TBCB MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304288 bait prey PTMA TBCB MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304292 bait prey NRF1 TBCB MI:0428(imaging technique) 24250222 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_296688 bait prey TWF2 TBCB MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304293 bait prey VCL TBCB MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304915 prey bait PDIA4 TBCB MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_301864 prey bait TPT1 TBCB MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_240901 prey bait PPP1CA TBCB MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_302106 prey bait MYO1E TBCB MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304290 bait prey TBCB ERP44 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304286 prey bait YWHAE TBCB MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_305160 prey bait TXNDC5 TBCB MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_239826 prey bait ASNS TBCB MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_298645 prey bait

PPI - HINT Gene A Gene B PMID Method Quality UBFD1 TBCB 22863883 0401 HT PROSC TBCB 22863883 0401 HT CAPNS1 TBCB 22863883 0401 HT ANXA6 TBCB 26344197 0401 HT ASNS TBCB 22863883 0401 HT PDIA4 TBCB 22863883 0401 HT TPT1 TBCB 22939629 0401 HT ALDH7A1 TBCB 22863883 0401 HT HK2 TBCB 26344197 0401 HT EIF5 TBCB 22863883 0401 HT CSE1L TBCB 22863883 0401 HT PPP1CA TBCB 22863883 0401 HT SNRPF TBCB 22863883 0401 HT MYO1E TBCB 22863883 0401 HT MAPRE1 TBCB 22863883 0401 HT PTMAP7 TBCB 22863883 0401 HT LGSN TBCB 26344197 0401 HT TWF2 TBCB 22863883 0401 HT D2HGDH TBCB 26344197 0401 HT OGFOD1 TBCB 22863883 0401 HT TXNDC5 TBCB 22939629 0401 HT PLBD2 TBCB 26344197 0401 HT FERMT2 TBCB 22863883 0401 HT PPP1R14B TBCB 26344197 0401 HT ISOC1 TBCB 22863883 0401 HT TBCB ERP44 22863883 0401 HT TBCB AARSD1 26344197 0401 HT TBCB Q9H4N8 22863883 0401 HT TBCB SCPEP1 22863883 0401 HT TBCB XPNPEP1 26344197 0401 HT TBCB STK26 22863883 0401 HT TBCB STK24 22863883 0401 HT TBCB HEL2 22863883 0401 HT TBCB HEL-S-29 22863883 0401 HT TBCB HEL-S-64P 22863883 0401 HT TBCB HEL114 22863883 0401 HT UBFD1 TBCB 22863883 0401 HT PROSC TBCB 22863883 0401 HT CAPNS1 TBCB 22863883 0401 HT ANXA6 TBCB 26344197 0401 HT ASNS TBCB 22863883 0401 HT PDIA4 TBCB 22863883 0401 HT TPT1 TBCB 22939629 0401 HT ALDH7A1 TBCB 22863883 0401 HT HK2 TBCB 26344197 0401 HT EIF5 TBCB 22863883 0401 HT CSE1L TBCB 22863883 0401 HT PPP1CA TBCB 22863883 0401 HT SNRPF TBCB 22863883 0401 HT MYO1E TBCB 22863883 0401 HT MAPRE1 TBCB 22863883 0401 HT PTMAP7 TBCB 22863883 0401 HT LGSN TBCB 26344197 0401 HT TWF2 TBCB 22863883 0401 HT D2HGDH TBCB 26344197 0401 HT OGFOD1 TBCB 22863883 0401 HT TXNDC5 TBCB 22939629 0401 HT PLBD2 TBCB 26344197 0401 HT FERMT2 TBCB 22863883 0401 HT PPP1R14B TBCB 26344197 0401 HT ISOC1 TBCB 22863883 0401 HT TBCB ERP44 22863883 0401 HT TBCB AARSD1 26344197 0401 HT TBCB Q9H4N8 22863883 0401 HT TBCB SCPEP1 22863883 0401 HT TBCB XPNPEP1 26344197 0401 HT TBCB STK26 22863883 0401 HT TBCB STK24 22863883 0401 HT TBCB HEL2 22863883 0401 HT TBCB HEL-S-29 22863883 0401 HT TBCB HEL-S-64P 22863883 0401 HT TBCB HEL114 22863883 0401 HT UBFD1 TBCB 22863883 0401 LC PROSC TBCB 22863883 0401 LC CAPNS1 TBCB 22863883 0401 LC ANXA6 TBCB 26344197 0401 LC ASNS TBCB 22863883 0401 LC PDIA4 TBCB 22863883 0401 LC TPT1 TBCB 22939629 0401 LC ALDH7A1 TBCB 22863883 0401 LC HK2 TBCB 26344197 0401 LC EIF5 TBCB 22863883 0401 LC CSE1L TBCB 22863883 0401 LC PPP1CA TBCB 22863883 0401 LC SNRPF TBCB 22863883 0401 LC MYO1E TBCB 22863883 0401 LC PAK1 TBCB 17389360 0018 LC MAPRE1 TBCB 22863883 0401 LC PTMAP7 TBCB 22863883 0401 LC LGSN TBCB 26344197 0401 LC TWF2 TBCB 22863883 0401 LC D2HGDH TBCB 26344197 0401 LC OGFOD1 TBCB 22863883 0401 LC TXNDC5 TBCB 22939629 0401 LC PLBD2 TBCB 26344197 0401 LC USP7 TBCB 16713569,16713569,16713569,16713569 0096,0397,0004,0018 HT FERMT2 TBCB 22863883 0401 LC PPP1R14B TBCB 26344197 0401 LC ISOC1 TBCB 22863883 0401 LC TBCB ERP44 22863883 0401 LC TBCB AARSD1 26344197 0401 LC TBCB GAN 16303566,16303566,16303566 0018,0007,0004 LC TBCB Q9H4N8 22863883 0401 LC TBCB SCPEP1 22863883 0401 LC TBCB XPNPEP1 26344197 0401 LC TBCB STK26 22863883 0401 LC TBCB STK24 22863883 0401 LC TBCB HEL2 22863883 0401 LC TBCB HEL-S-29 22863883 0401 LC TBCB HEL-S-64P 22863883 0401 LC TBCB HEL114 22863883 0401 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q99426 Q8N543 TBCB OGFOD1 0.081 22863883 Q99426 Q6IBS0 TBCB TWF2 0.081 22863883 Q99426 P04629 TBCB NTRK1 0.126 25921289 Q99426 P06454 TBCB PTMA 0.081 22863883 Q9H2C0 Q99426 GAN TBCB 0.765 16303566 Q99426 Q96AC1 TBCB FERMT2 0.081 22863883 Q99426 Q96FW1 TBCB OTUB1 0.126 26752685 Q9BS26 Q99426 ERP44 TBCB 0.081 22863883 Q9BTE6 Q99426 AARSD1 TBCB 0.081 26344197 Q99426 P04632 TBCB CAPNS1 0.081 22863883 Q99426 P08133 TBCB ANXA6 0.081 26344197 Q99426 O14562 TBCB UBFD1 0.081 22863883 Q99426 Q5TDP6 TBCB LGSN 0.081 26344197 Q99426 P49419 TBCB ALDH7A1 0.081 22863883 Q99426 P12277 TBCB CKB 0.081 22863883 Q99426 P08243 TBCB ASNS 0.081 22863883 Q99426 P18206 TBCB VCL 0.081 22863883 Q99426 P13667 TBCB PDIA4 0.081 22863883 Q99426 P13693 TBCB TPT1 0.081 22939629 Q99426 Q15691 TBCB MAPRE1 0.081 22863883 Q99426 P62136 TBCB PPP1CA 0.081 22863883 Q99426 P52789 TBCB HK2 0.081 26344197 Q99426 Q04917 TBCB YWHAH 0.081 22863883 Q99426 P62258 TBCB YWHAE 0.081 22863883 Q99426 P62306 TBCB SNRPF 0.081 22863883 Q99426 Q96CN7 TBCB ISOC1 0.081 22863883 Q99426 Q8NBS9 TBCB TXNDC5 0.081 22939629 Q99426 Q81K51 TBCB Q81K51 0.126 20711500 Q99426 Q8N465 TBCB D2HGDH 0.081 26344197 Q99426 Q96C90 TBCB PPP1R14B 0.081 26344197 Q99426 Q8NHP8 TBCB PLBD2 0.081 26344197 Q99426 Q93009 TBCB USP7 0.523 16713569 Q9NQW7 Q99426 XPNPEP1 TBCB 0.081 26344197 Q9HB40 Q99426 SCPEP1 TBCB 0.081 22863883 Q9Y6E0 Q99426 STK24 TBCB 0.081 22863883 Q9P289 Q99426 MST4 TBCB 0.081 22863883 Q99426 P62807 TBCB HIST1H2BI 0.126 25281560 Q99426 P48637 TBCB GSS 0.081 22863883 Q99426 Q12965 TBCB MYO1E 0.081 22863883 Q99426 Q15717 TBCB ELAVL1 0.126 19322201 Q99426 Q16666 TBCB IFI16 0.126 25665578 Q99426 P55010 TBCB EIF5 0.081 22863883 Q99426 P55060 TBCB CSE1L 0.081 22863883

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 TUBAL3 TBCB MI:0362 inference MI:0461,MI:1106 interaction database,pathways database NTRK1 TBCB MI:0045 experimental interaction detection MI:0461 interaction database UBC TBCB MI:0045 experimental interaction detection MI:0461 interaction database HSPA1A TBCB MI:0362 inference MI:0461 interaction database HSPA1B TBCB MI:0362 inference MI:0461 interaction database HSPA8 TBCB MI:0362 inference MI:0461 interaction database HSPA6 TBCB MI:0362 inference MI:0461 interaction database TSPO TBCB MI:0362 inference MI:0461 interaction database HSPA1L TBCB MI:0362 inference MI:0461 interaction database PSMC2 TBCB MI:0362 inference MI:0461 interaction database HNF4A TBCB MI:0045 experimental interaction detection MI:0461 interaction database CCT5 TBCB MI:0362 inference MI:0461 interaction database HSPA2 TBCB MI:0362 inference MI:0461 interaction database SUMO2 TBCB MI:0045 experimental interaction detection MI:0461 interaction database YWHAG TBCB MI:0362 inference MI:0461 interaction database CNBP TBCB MI:0362 inference MI:0461 interaction database HIST1H2BC TBCB MI:0045 experimental interaction detection MI:0461 interaction database TUBA1B TBCB MI:0362 inference MI:0461,MI:1106 interaction database,pathways database TUBA4A TBCB MI:0362 inference MI:0461,MI:1106 interaction database,pathways database YWHAH TBCB MI:0362 inference MI:0461 interaction database PAK1 TBCB MI:0362 inference MI:0461 interaction database TUBA3C TBCB MI:0362 inference MI:0461,MI:1106 interaction database,pathways database ELAVL1 TBCB MI:0045 experimental interaction detection MI:0461 interaction database TBCE TBCB MI:0362 inference MI:1106 pathways database IFI16 TBCB MI:0045 experimental interaction detection MI:0461 interaction database TUBA3E TBCB MI:0362 inference MI:0461,MI:1106 interaction database,pathways database TUBA1A TBCB MI:0362 inference MI:0461,MI:1106 interaction database,pathways database ZCCHC13 TBCB MI:0362 inference MI:0461 interaction database USP7 TBCB MI:0045 experimental interaction detection MI:0461 interaction database OTUB1 TBCB MI:0045 experimental interaction detection MI:0461 interaction database TBCB TUBA1C MI:0362 inference MI:1106 pathways database TBCB GAN MI:0045 experimental interaction detection MI:0461 interaction database TBCB TUBA4B MI:0362 inference MI:1106 pathways database TBCB TUBA8 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database