PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus DDX58 CASP9 23484008 innatedb exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 PCBP1 22105485 innatedb exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 ZC3HAV1 21102435 innatedb,intact exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 RAI14 21903422 innatedb,biogrid,intact exp GP GP GP G G GP G GP GP GP G G G GP G P G GP GP G P G G GP GP G DDX58 RNF31 21292167 biogrid exp P P G G GP GP P G GP GP GP P GP GP P P G GP P P GP GP GP P GP DDX58 UBE2D2 17719635 biogrid exp GP G G G GP GP G G GP G GP GP GP GP G G GP GP P G GP GP G GP G GP GP GP G TSPAN6 DDX58 22908223 innatedb,biogrid exp GP G G G G GP G G GP G GP GP GP G G GP GP G P G GP GP GP G GP G GP GP G DDX58 IKBKG 23950712 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G DDX58 UBE2K 17719635 biogrid exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 CASP1 23592984 innatedb exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP G GP GP G DDX58 TRIM32 22745133 biogrid exp GP GP G G G GP G G GP G GP GP G GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 PRKCA 22114345 biogrid exp G GP G G GP GP G G GP G GP G G GP G GP GP G P G GP G G GP GP G GP GP G DDX58 PRKCG 22114345 biogrid exp G G G G G GP G G G G G G G GP G G G G G G G DDX58 RBCK1 21292167 biogrid exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 WRNIP1 21903422 innatedb,biogrid,intact exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 NOD2 21690088 innatedb exp P G GP P P GP P P P P P P P P P GP P DDX3X DDX58 20127681 innatedb,intact exp G GP G G GP GP G G GP G G G GP GP G GP GP G P G GP GP GP G GP GP GP GP G DDX58 G3BP1 22912779 innatedb exp GP GP G G GP GP G G GP G GP G GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 UBA52 24590070 dip exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 SRC 19419966 biogrid exp GP GP G GP G G G GP G G G G GP GP G G GP GP G GP GP GP GP G DDX58 CASP8 21419663 innatedb exp GP GP G GP P G GP GP GP GP GP G GP P GP P G GP GP GP P GP GP GP GP G DDX58 RNF5 19285439 innatedb exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP G P G GP GP GP GP GP G GP GP G DDX58 USP15 26061460 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G PRKRIR DDX58 21910972 biogrid exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 VAPA 26496610 biogrid,intact exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 BIRC2 21419663 innatedb exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP G P G GP G GP GP GP GP GP GP G DDX58 USP3 24366338 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G PRKRA DDX58 23870315 intact exp GP GP G G GP GP G G GP G GP G GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 PYCARD 23592984,19915568 innatedb exp GP GP G G GP P G G GP G P GP GP GP G GP P GP P G GP GP GP P GP GP GP P G DDX58 TIA1 26344197 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G DDX58 SEC14L1 23843640 innatedb exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 USP21 24493797 biogrid exp GP GP G G G GP G G GP G GP GP GP G G GP GP G P G GP GP GP G GP G GP GP G DDX58 MBP 23264040 biogrid exp G G G G G GP G G G G G G G GP G G G G G G G G DDX58 ELAVL1 22912779 innatedb exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP G GP GP G DDX58 TNFAIP3 16306043 innatedb exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP G GP GP G DDX58 CC2D1A 22833682 innatedb exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 PRKCB 22114345 biogrid exp GP GP G G GP GP G G GP G GP G GP GP G G GP GP P G G GP GP G G GP GP GP G DDX58 NLRC5 20434986 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G DDX58 PPP1R3A 23499489 innatedb exp G G G DDX58 UBC 20403326,23264040,18636086 biogrid,mint,intact exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 TIAL1 22912779 innatedb exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G DDX58 MEX3C 24706898 biogrid exp P P GP GP P G GP P P P G P P GP P GP G DDX58 DDX58 23264040,25259935,18948594,21102435,17190814 innatedb,biogrid,intact,dip exp, ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 USP4 23388719 innatedb,biogrid exp, ortho G GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP G GP GP GP G GP GP G DDX58 TRIM25 25172487,21292167,20818395,22114345,17392790,24478431,19675569,23264040,20406818,18948594,20071582,19484123,23950712, 25402006, 21836163 innatedb,biogrid,intact exp, ortho, pred G GP G G GP GP G G GP G GP G GP GP G GP GP GP P G GP GP GP G GP GP GP GP G DDX58 TBK1 16281057,21419663,23950712, 25402006 innatedb,biogrid exp, ortho, pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 MAVS 21903422,23499489,22022264,16585524,16127453,26061460,17190814,19454348,19193793,21292167,21844353,20554965,24478431,16177806,20406818,20007272,21419663,18207245,20434986,21102435,22623778,22301138,17020950,19164550,21200404,18948594,20071582,16153868,19881509,22844514,18977754,22114345,19036819,23843640, 25402006, 21836163 innatedb,hprd,biogrid,i2d,intact,dip exp, ortho, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 UBE2D1 17719635, 25402006 biogrid exp, pred GP G G G GP GP G G GP G GP GP GP GP G G GP GP P G GP GP G GP G GP GP GP G DDX58 UBE2D3 17719635, 25402006 biogrid exp, pred GP G G G GP GP G G GP G GP GP GP GP G G GP GP P G GP GP G GP G GP GP GP G DDX58 TRAF3 21844353, 25402006 innatedb,dip exp, pred G GP G G GP GP G G G G GP GP GP GP G GP GP GP P G GP G GP G GP G GP GP G DDX58 RNF125 17460044, 25402006, 21836163 innatedb,dip exp, pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP P G GP GP GP GP GP GP GP P G DDX58 ATG5 17709747, 25402006 innatedb,dip exp, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G ATG12 DDX58 17709747, 25402006 innatedb,dip exp, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 RNF135 19017631,19484123,23950712, 25402006, 21836163 innatedb,biogrid exp, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G P G GP GP GP GP GP G GP GP G DDX58 TMEM173 18818105,18724357, 25402006 innatedb,dip exp, pred GP G G G GP GP G G GP G G G GP GP G G GP G P G GP GP GP G G GP GP GP G IFIT3 DDX58 21813773, 25402006 innatedb,biogrid exp, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP G GP GP GP G GP G GP GP G DDX58 IKBKE 16281057,23950712, 25402006, 21836163 innatedb,biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G DDX58 AZI2 17142768, 25402006 innatedb exp, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 STAT1 24360797, 25402006 intact exp, pred G G G G GP GP G G GP G GP G GP GP G GP GP G P G GP GP G G GP GP G GP G DDX58 CYLD 18467330,18636086, 25402006 innatedb,hprd,biogrid,mint,intact exp, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP DDX58 PCBP2 19881509, 25402006 innatedb exp, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 ISG15 24448099,16009940, 25402006 innatedb,biogrid exp, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 MAP3K14 18550535, 25402006 innatedb exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G DDX58 IRF3 18636086,16153868, 25402006 innatedb,biogrid exp, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP G GP GP GP GP G DDX58 DHX58 17020950,17190814, 25402006, 23023127 innatedb,dip exp, pred P P P P P P P P P P P P P P DDX58 DLD ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 NPEPPS ortho GP GP G G GP GP G G GP G GP GP G G G GP GP G P G G GP G GP GP G GP GP G DDX58 TKTL2 ortho P P P P P P P P P P P P P P P P GP DDX58 GPKOW ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 CCT8 ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 SNRPD1 ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G DDX58 PTPN11 ortho GP GP G G G GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP G GP GP GP GP G DDX58 TUBB4B ortho GP G G G G GP G G GP G G G G GP G GP GP G P G GP GP GP G GP GP GP GP G DDX58 TANK ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 ENO1 ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 PCCB ortho GP GP G G G GP G G GP G GP GP GP GP G GP GP G P G GP GP GP G GP G GP GP G DUSP11 DDX58 ortho G GP G G G GP G G GP G GP G G G G GP GP G P G GP G GP G GP G GP GP G DDX58 CBL ortho G GP G G GP GP G G GP G GP G GP GP G G GP GP G G G G G G GP G GP G DDX58 PC ortho GP GP G GP G P G GP GP P G G P GP P G GP GP GP P P P GP G DDX58 TCP1 ortho P P P P P P P P P P P P P P P P P P P P P DDX58 HSPD1 ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP G GP GP GP GP G DDX58 SNRPN ortho G GP G GP DDX58 GCDH ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 EEF2 ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 NACA2 ortho G DDX58 GBE1 ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 RPS12 ortho GP GP G G GP GP G G GP G GP G GP GP G GP GP GP P G GP GP GP G GP GP GP GP G DDX58 CCT7 ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 RPL3 ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP G GP GP GP GP G DDX58 ATP5B ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 COPB2 ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP G P G GP GP GP GP GP G GP GP G DDX58 CCT2 ortho GP GP G G GP GP G G GP G G GP GP GP G GP GP G P G GP GP G G GP GP GP GP G DDX58 CTSZ ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G G GP GP GP GP GP GP GP G DDX58 TRIM71 ortho P P P P P P P P P P P P P P P P P DDX58 SIGLEC10 ortho G G G GP GP G P G GP GP G G GP P P G G P G GP GP P G DDX58 TROVE2 ortho G GP G G GP GP G G G G GP GP GP G G GP GP G P G GP GP GP G GP GP GP GP G DDX58 TAF6 ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 ST13 ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 RPL8 ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 ERI1 ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G SNRNP200 DDX58 ortho GP G G G GP GP G G GP G GP G GP GP G GP GP G P G GP GP GP G GP GP GP GP G DDX58 PSMD13 ortho GP GP G G GP GP G G GP G GP G GP GP G GP GP G P G GP GP GP GP GP GP GP GP G DDX58 RPS13 ortho P P P P P P P P P P P P P DDX58 HSPE1 25402006 ortho, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 DDX60 25402006 ortho, pred GP GP G GP P G G GP GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP P G DDX58 PIN1 25402006 pred G GP G G GP GP G G GP G G G G GP G G GP G P G P GP G G G G GP GP G DDX58 FADD 25402006 pred GP GP G G G GP G G GP G GP G GP GP G GP GP G P G GP G GP GP GP GP GP GP G DDX58 SP110 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 HERC5 25402006 pred G GP G G G GP G G GP G GP GP G G G GP GP G G GP G G GP GP G GP GP G DDX58 IFI27 25402006 pred GP GP G G GP GP G G GP G GP G G GP G GP GP G P G GP G G GP GP GP GP G G DDX58 TNFSF10 25402006 pred GP GP G G G GP G G GP G GP G GP GP G GP GP GP P G GP GP GP G GP G GP P G DDX58 IRF7 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 TECPR1 25402006 pred GP GP G G GP GP G G GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G DDX58 ATG3 25402006 pred GP GP G G GP GP G G GP G GP GP GP G G GP GP G P G GP GP GP G GP GP GP GP G DDX58 OTUD5 25402006 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP G GP GP G DDX58 ATG10 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP P GP GP P G GP GP GP GP GP P P P G DDX58 PITX2 25402006 pred G G G G G G DDX58 MX1 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP G GP GP GP GP G DDX58 PSMC1 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP G GP GP GP GP G DDX58 TRIM22 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 TRAF6 25402006 pred GP GP G G GP G G G GP G GP GP GP G G GP G GP G GP GP GP G GP GP GP GP G ATG7 DDX58 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 IRF5 25402006 pred G G G G GP GP G G G G G G G GP G G GP G G G G G G G GP G GP G DDX58 PPIB 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP G GP GP GP GP G DDX58 IRF9 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP G GP GP G DDX58 CREBBP 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 USP18 25402006 pred GP P G G GP G G G G G P GP P G G G GP G DDX58 HDAC6 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G IKBKB DDX58 25402006 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP P G GP GP GP G GP GP GP GP G DDX58 IFIT1 25402006 pred G GP G GP G G GP G GP GP GP GP G GP GP G P G G GP GP GP GP G GP GP DDX58 RSAD2 25402006 pred G GP G G GP GP G G GP G GP GP GP G G P GP GP P G GP G G GP GP GP GP P G DDX58 TICAM1 25402006 pred GP GP G P G G GP GP GP GP GP G GP P GP P GP GP GP GP GP GP GP P G DDX58 TRAF2 25402006 pred P P P P P P P P P P P P P P P P P P GP GP P DDX58 IFI44 25402006 pred G GP G G GP GP G G GP G GP GP GP G G G GP G P G GP G GP GP G GP G GP G DDX58 IFI44L 25402006 pred GP GP G G GP GP G G GP G GP G G G G GP GP G P G P GP GP GP GP GP GP GP DDX58 HERC6 25402006 pred G G G P GP G G GP G GP G G GP G G GP G P G GP G G G G GP G G G DDX58 OAS2 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 XAF1 25402006 pred G GP G G GP GP G G GP G GP GP G G G GP GP GP P G GP G GP G GP G GP GP G DDX58 ESR1 25402006 pred GP G G G G G G G G G G G G G G G G G G G G G G G G G G G DDX58 OAS3 25402006 pred GP G G G G G G G GP G GP G GP GP G GP G G P G GP G GP G GP G GP GP G DDX58 RARRES3 25402006 pred GP G G G G GP G G G G GP G GP G G G GP G G G G G G G G G G G DDX58 RBBP4 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G DDX58 SIKE1 21836163 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP G GP GP G DDX58 TRIM21 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G UBE2L6 DDX58 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP G GP GP GP GP G DDX58 PLK1 25402006 pred P P G G GP P G G GP P P P GP GP GP GP P G GP P GP GP GP P P GP DDX58 IFIT5 25402006 pred G G G G G GP G G G G G G G G G G GP G G G G G G G GP G G DDX58 IFIH1 25402006, 23023127 pred GP GP P P G GP GP GP GP GP G GP P G P G GP GP GP P GP GP GP P DDX58 CCL5 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G MFN2 DDX58 25402006 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP G P G GP GP GP GP GP GP GP GP G DDX58 IFIT2 25402006 pred G G G G GP G G G G G GP G G GP G G G G G G G G G G G G G G DDX58 TDRD7 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G P G GP G G GP GP GP GP GP G DDX58 CXCL10 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G DDX58 OAS1 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP P G DDX58 ATG16L1 25402006 pred GP G GP GP G G GP GP G G G GP G G G G G GP G G G DDX58 PARP12 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP G GP GP GP GP G TRAF5 DDX58 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G DDX58 MX2 25402006 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP G P G GP GP G G GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P61077-3 O95786 enzymatic study 17719635 direct interaction X 2 P12931 O95786 affinity chromatography technology 19419966 physical association X 2 P05129 O95786 enzymatic study 22114345 direct interaction X 2 A0A024R843 O95786 affinity chromatography technology 22745133 physical association X 2 A0A087WW00 O95786 enzymatic study 17719635 direct interaction X 2 A0A024R384 O95786 affinity chromatography technology 23264040 physical association X 2 A0A024R384 O95786 affinity chromatography technology 23264040 physical association X 2 Q61510 O95786 enzymatic study 23209422 direct interaction X 2 Q61510 O95786 affinity chromatography technology 20818395 physical association X 2 O95786 E2GIM6 affinity chromatography technology 16153868 physical association X 2 O95786 Q13107-3 affinity chromatography technology 23388719 physical association X 2 O95786 Q13107-3 affinity chromatography technology 23388719 physical association X 2 O95786 O08736 affinity chromatography technology 20818395 physical association X 2 O95786 O08736 pull down 20818395 direct interaction X 2 O95786 Q8IUD6-3 affinity chromatography technology 23950712 physical association X 2 O95786 Q8IUD6-3 affinity chromatography technology 19484123 physical association X 2 O95786 Q8IUD6-3 affinity chromatography technology 19484123 physical association X 2 O95786 Q8IUD6-3 two hybrid 19484123 direct interaction X 2 O95786 Q8IUD6-3 enzymatic study 19484123 direct interaction X 2 O95786 E2GIM6 affinity chromatography technology 18636086 physical association X 2 O95786 affinity chromatography technology 21292167 physical association X 2 O95786 P05771 enzymatic study 22114345 direct interaction X 2 O95786 P05771 affinity chromatography technology 22114345 physical association X 2 O95786 P05771 affinity chromatography technology 22114345 physical association X 2 Q96EP0 O95786 affinity chromatography technology 21292167 physical association X 2 Q96EP0 O95786 affinity chromatography technology 21292167 physical association X 2 O43422 O95786 pull down 21910972 direct interaction X 2 Q7Z434-4 O95786 affinity chromatography technology 16177806 physical association X 2 Q7Z434-4 O95786 affinity chromatography technology 16153868 physical association X 2 Q7Z434-4 O95786 affinity chromatography technology 20434986 physical association X 2 Q7Z434-4 O95786 affinity chromatography technology 20554965 physical association X 2 Q7Z434-4 O95786 affinity chromatography technology 20071582 physical association X 2 Q7Z434-4 O95786 affinity chromatography technology 19454348 physical association X 2 Q7Z434-4 O95786 affinity chromatography technology 20406818 physical association X 2 Q7Z434-4 O95786 affinity chromatography technology 16127453 physical association X 2 Q7Z434-4 O95786 affinity chromatography technology 21903422 physical association X 2 Q7Z434-4 O95786 affinity chromatography technology 21903422 physical association X 2 Q7Z434-4 O95786 affinity chromatography technology 21292167 physical association X 2 Q7Z434-4 O95786 affinity chromatography technology 22022264 physical association X 2 Q7Z434-4 O95786 affinity chromatography technology 22114345 physical association X 2 O95786 enzymatic study 22114345 direct interaction X 2 O95786 affinity chromatography technology 22114345 physical association X 2 O95786 affinity chromatography technology 22114345 physical association X 2 P05161 O95786 affinity chromatography technology 16009940 physical association X 2 P05161 O95786 affinity chromatography technology 16009940 physical association X 2 P05161 O95786 affinity chromatography technology 17719635 physical association X 2 O95786 affinity chromatography technology 23950712 physical association X 2 O43657 O95786 affinity chromatography technology 22908223 physical association X 2 Q9UHD2 O95786 affinity chromatography technology 23950712 physical association X 2 A0A024R6T1 O95786 affinity chromatography technology 18636086 physical association X 2 Q86WI3 O95786 affinity chromatography technology 20434986 physical association X 2 Q14258 O95786 enzymatic study 23209422 direct interaction X 2 Q14258 O95786 affinity chromatography technology 23950712 physical association X 2 Q14258 O95786 enzymatic study 25172487 direct interaction X 2 Q14258 O95786 enzymatic study 19675569 direct interaction X 2 Q14258 O95786 pull down 23264040 direct interaction X 2 Q14258 O95786 affinity chromatography technology 19484123 physical association X 2 Q14258 O95786 affinity chromatography technology 19484123 physical association X 2 Q14258 O95786 affinity chromatography technology 17392790 physical association X 2 Q14258 O95786 pull down 17392790 direct interaction X 2 Q14258 O95786 enzymatic study 17392790 direct interaction X 2 Q14258 O95786 affinity chromatography technology 20071582 physical association X 2 Q14258 O95786 affinity chromatography technology 20406818 physical association X 2 Q14258 O95786 affinity chromatography technology 20406818 physical association X 2 Q14258 O95786 affinity chromatography technology 21292167 physical association X 2 Q14258 O95786 affinity chromatography technology 21292167 physical association X 2 Q14258 O95786 affinity chromatography technology 22114345 physical association X 2 Q9P0K7-3 O95786 affinity chromatography technology 21903422 physical association X 2 Q9Y6I4 O95786 affinity chromatography technology 24366338 physical association X 2 Q9Y6I4 O95786 enzymatic study 24366338 direct interaction X 2 P61086 O95786 enzymatic study 17719635 direct interaction X 2 O95786 O95786 pull down 23264040 direct interaction X 2 O95786 P0CG50 affinity chromatography technology 20818395 physical association X 2 O95786 affinity chromatography technology 23950712 physical association X 2 O95786 Q9UK80 affinity chromatography technology 24493797 physical association X 2 O95786 Q9UK80 affinity chromatography technology 24493797 physical association X 2 O95786 Q9UK80 imaging technique 24493797 colocalization X 2 O95786 P62837 enzymatic study 17719635 direct interaction X 2 P0CG48 O95786 affinity chromatography technology 23209422 physical association X 2 P0CG48 O95786 affinity chromatography technology 23388719 physical association X 2 P0CG48 O95786 affinity chromatography technology 23399697 physical association X 2 P0CG48 O95786 affinity chromatography technology 23000965 physical association X 2 P0CG48 O95786 affinity chromatography technology 23950712 physical association X 2 P0CG48 O95786 affinity chromatography technology 24493797 physical association X 2 P0CG48 O95786 affinity chromatography technology 24622840 physical association X 2 P0CG48 O95786 affinity chromatography technology 24366338 physical association X 2 P0CG48 O95786 affinity chromatography technology 24706898 physical association X 2 P0CG48 O95786 affinity chromatography technology 19484123 physical association X 2 P0CG48 O95786 pull down 23264040 direct interaction X 2 P0CG48 O95786 pull down 20403326 direct interaction X 2 P0CG48 O95786 affinity chromatography technology 18636086 physical association X 2 P0CG48 O95786 affinity chromatography technology 17719635 physical association X 2 P0CG48 O95786 affinity chromatography technology 17392790 physical association X 2 P0CG48 O95786 affinity chromatography technology 21835791 physical association X 2 P0CG48 O95786 affinity chromatography technology 19996094 physical association X 2 P0CG48 O95786 affinity chromatography technology 20071582 physical association X 2 P0CG48 O95786 affinity chromatography technology 19454348 physical association X 2 P0CG48 O95786 affinity chromatography technology 21292167 physical association X 2 P0CG48 O95786 affinity chromatography technology 22022264 physical association X 2 P0CG48 O95786 affinity chromatography technology 21910972 physical association X 2 P0CG48 O95786 affinity chromatography technology 22114345 physical association X 2 P0CG48 O95786 affinity chromatography technology 21906983 physical association X 2 Q5U5Q3 O95786 affinity chromatography technology 24706898 physical association X 2 Q96S55-2 O95786 affinity chromatography technology 21903422 physical association X 2 Q96S55-2 O95786 pull down 21903422 direct interaction X 2 Q14258 O95786 pull down 17392790 association X 2 O95786 anti tag coimmunoprecipitation 17460044 - C 3 O95786 anti bait coimmunoprecipitation 20080758 - C 5 O94817 O95786 anti tag coimmunoprecipitation 17709747 physical association X 2 O94817 O95786 anti tag coimmunoprecipitation 17709747 physical association X 2 A9UGY9 O95786 anti tag coimmunoprecipitation 17709747 direct interaction X 2 A9UGY9 O95786 anti tag coimmunoprecipitation 17709747 direct interaction X 2 A9UGY9 O95786 pull down 17709747 direct interaction X 2 A9UGY9 O95786 anti tag coimmunoprecipitation 17709747 direct interaction X 2 Q13114 O95786 anti bait coimmunoprecipitation 21844353 physical association X 2 O95786 O95786 comigration in non denaturing gel electrophoresis 24590070 direct interaction Y 1 O95786 O95786 anti tag coimmunoprecipitation 17190814 direct interaction Y 1 O95786 O95786 anti tag coimmunoprecipitation 17190814 direct interaction Y 1 O95786 O95786 x-ray crystallography 20581823 direct interaction Y 1 O95786 P62987 pull down 17460044 direct interaction X 2 O95786 P62987 x-ray crystallography 24590070 direct interaction X 2 O95786 P62987 anti tag coimmunoprecipitation 17460044 direct interaction X 2 O95786 anti bait coimmunoprecipitation 21844353 - C 3 O95786 anti tag coimmunoprecipitation 17709747 - C 3 O95786 anti tag coimmunoprecipitation 17709747 - C 4 A0A024R1Y5 O95786 anti tag coimmunoprecipitation 17190814 physical association X 2 Q7Z434 O95786 anti tag coimmunoprecipitation 19164550 physical association X 2 Q7Z434 O95786 anti bait coimmunoprecipitation 21844353 physical association X 2 Q7Z434 O95786 anti tag coimmunoprecipitation 17709747 physical association X 2 Q7Z434 O95786 anti tag coimmunoprecipitation 16585524 physical association X 2 Q7Z434 O95786 anti bait coimmunoprecipitation 18200010 physical association X 2 Q7Z434 O95786 anti tag coimmunoprecipitation 17190814 physical association X 2 Q7Z434 O95786 anti tag coimmunoprecipitation 17709747 physical association X 2 Q7Z434 O95786 anti bait coimmunoprecipitation 20080758 physical association X 2 Q96EQ8 O95786 anti tag coimmunoprecipitation 17460044 physical association X 2 Q96EQ8 O95786 anti tag coimmunoprecipitation 17460044 physical association X 2 Q96EQ8 O95786 anti tag coimmunoprecipitation 17460044 physical association X 2 Q96EQ8 O95786 anti tag coimmunoprecipitation 17460044 physical association X 2 Q96EQ8 O95786 anti bait coimmunoprecipitation 17460044 physical association X 2 Q86WV6 O95786 anti bait coimmunoprecipitation 18724357 physical association X 2 Q86WV6 O95786 anti tag coimmunoprecipitation 18724357 physical association X 2 Q7Z434-4 O95786 in vivo 16177806 - X 2 Q7Z434-4 O95786 in vivo 16177806 - X 2 A0A024R6T1 O95786 in vivo 18636086 - X 2 A0A024R6T1 O95786 in vitro 18636086 - X 2 A0A024R6T1 O95786 in vivo 18636086 - X 2 A0A024R6T1 O95786 in vitro 18636086 - X 2 O95786 pull down 20818395 association C 3 O95786 anti tag coimmunoprecipitation 21903422 association C 4 O95786 bimolecular fluorescence complementation 24478431 colocalization C 3 O95786 anti tag coimmunoprecipitation 24478431 association C 3 O95786 bimolecular fluorescence complementation 24478431 colocalization C 3 O95786 anti tag coimmunoprecipitation 22301138 physical association C 3 O95786 anti tag coimmunoprecipitation 22301138 physical association C 3 O95786 confocal microscopy 22623778 colocalization C 3 Q6UY71 O95786 anti bait coimmunoprecipitation 20007272 direct interaction X 2 Q6UY71 O95786 anti tag coimmunoprecipitation 20007272 physical association X 2 Q6UY71 O95786 anti tag coimmunoprecipitation 20007272 physical association X 2 Q7Z2W4 O95786 anti bait coimmunoprecipitation 21102435 physical association X 2 Q7Z2W4 O95786 anti tag coimmunoprecipitation 21102435 physical association X 2 Q7Z2W4 O95786 anti bait coimmunoprecipitation 21102435 physical association X 2 O95786 Q920D5 pull down 20818395 direct interaction X 2 O95786 Q920D5 fluorescence microscopy 20818395 colocalization X 2 O95786 Q920D5 fluorescence microscopy 20818395 colocalization X 2 O95786 O95786 comigration in gel electrophoresis 21102435 physical association Y 1 O95786 Q6WB94 anti tag coimmunoprecipitation 23015697 physical association X 2 O95786 O75569 anti tag coimmunoprecipitation 23870315 physical association X 2 O95786 O75569 anti bait coimmunoprecipitation 23870315 physical association X 2 P04487 O95786 anti tag coimmunoprecipitation 22301138 physical association X 2 P04487 O95786 anti tag coimmunoprecipitation 22301138 physical association X 2 P04487 O95786 anti bait coimmunoprecipitation 22301138 physical association X 2 P04487 O95786 anti tag coimmunoprecipitation 22301138 physical association X 2 P21699 O95786 anti tag coimmunoprecipitation 23552410 physical association X 2 P21699 O95786 anti tag coimmunoprecipitation 23552410 physical association X 2 P21699 O95786 anti tag coimmunoprecipitation 23552410 physical association X 2 P42224 O95786 anti bait coimmunoprecipitation 24360797 physical association X 2 P42224 O95786 anti bait coimmunoprecipitation 24360797 physical association X 2 P42224 O95786 anti bait coimmunoprecipitation 24360797 physical association X 2 P42224 O95786 anti bait coimmunoprecipitation 24360797 physical association X 2 O95786 anti tag coimmunoprecipitation 21903422 association C 11 Q6UY62 O95786 anti tag coimmunoprecipitation 20007272 physical association X 2 Q6UY62 O95786 anti tag coimmunoprecipitation 20007272 physical association X 2 O00571 O95786 anti tag coimmunoprecipitation 20127681 physical association X 2 O00571 O95786 anti tag coimmunoprecipitation 20127681 physical association X 2 Q9NQC7 O95786 anti tag coimmunoprecipitation 18636086 physical association X 2 Q9NQC7 O95786 anti bait coimmunoprecipitation 18636086 physical association X 2 Q14258 O95786 bimolecular fluorescence complementation 24478431 physical association X 2 Q7Z2W4-2 O95786 anti tag coimmunoprecipitation 21102435 physical association X 2 Q7Z2W4-2 O95786 surface plasmon resonance 21102435 physical association X 2 Q7Z2W4-2 O95786 confocal microscopy 21102435 colocalization X 2 Q7Z2W4-2 O95786 fluorescent resonance energy transfer 21102435 physical association X 2 P04543 O95786 anti tag coimmunoprecipitation 19193793 physical association X 2 P04543 O95786 anti tag coimmunoprecipitation 19193793 physical association X 2 O95786 Q6IVU5 anti tag coimmunoprecipitation 20007272 physical association X 2 O95786 Q6IUF9 anti tag coimmunoprecipitation 20007272 physical association X 2 O95786 Q6IVU5 anti bait coimmunoprecipitation 20007272 direct interaction X 2 O95786 Q6IVU5 anti tag coimmunoprecipitation 20007272 physical association X 2 O95786 Q6IUF9 anti bait coimmunoprecipitation 20007272 direct interaction X 2 O95786 Q6IUF9 anti tag coimmunoprecipitation 20007272 physical association X 2 O95786 O95786 anti tag coimmunoprecipitation 21102435 physical association X 2 O95786 F1BA49 confocal microscopy 24478431 colocalization X 2 O95786 F1BA49 anti tag coimmunoprecipitation 24478431 physical association X 2 O95786 F1BA49 confocal microscopy 24478431 colocalization X 2 Q7Z434 O95786 anti tag coimmunoprecipitation 16177806 physical association X 2 Q7Z434 O95786 anti tag coimmunoprecipitation 19164550 physical association X 2 Q7Z434 O95786 anti tag coimmunoprecipitation 19193793 physical association X 2 Q7Z434 O95786 anti tag coimmunoprecipitation 19193793 physical association X 2 Q7Z434 O95786 anti bait coimmunoprecipitation 20007272 physical association X 2 Q7Z434 O95786 anti tag coimmunoprecipitation 21102435 physical association X 2 Q7Z434 O95786 anti tag coimmunoprecipitation 22301138 physical association X 2 Q7Z434 O95786 bimolecular fluorescence complementation 24478431 physical association X 2 P0CG48 O95786 anti tag coimmunoprecipitation 18636086 physical association X 2 Q96S55 O95786 anti tag coimmunoprecipitation 21903422 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B DDX58 RAI14 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 21903422 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association)|MI:0914(association) (biogrid)|(intact)|(intact) BIOGRID_155716|UniProt_115777|UniProt_172519 bait|bait|bait prey|prey|prey DDX58 WRNIP1 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 21903422 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|(biogrid)|(intact)|(intact)|(biogrid) UniProt_115777|UniProt_172519|BIOGRID_155717|UniProt_172654|UniProt_115918|BIOGRID_155968 bait|bait|bait|prey|prey|bait prey|prey|prey|bait|bait|prey DDX58 RNF31 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21292167 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_158747|BIOGRID_158748 prey|bait bait|prey DDX58 SRC MI:0004(affinity chromatography technology) 19419966 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_214759 bait prey DDX58 RNF135 MI:0004(affinity chromatography technology) 23950712 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_284776 bait prey DDX58 ISG15 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16009940,17719635 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_118750|BIOGRID_196259|BIOGRID_196139 bait|bait|prey prey|prey|bait DDX58 PRKCG MI:0004(affinity chromatography technology) 22114345 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_160766 prey bait DDX58 PRKCB MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22114345 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_160770|BIOGRID_160768|BIOGRID_160765 prey|bait|prey bait|prey|bait DDX58 UBE2K MI:0004(affinity chromatography technology) 17719635 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_118752 prey bait DDX58 UBE2D3 MI:0004(affinity chromatography technology) 17719635 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_118755 prey bait DDX58 ATG5 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 17709747 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|-|MI:0407(direct interaction) MI:0465(dip)|MI:0465(dip)|MI:0465(dip) DIP_54557|DIP_54561|DIP_54562 -|-|- -|-|- ATG12 DDX58 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 17709747 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|- MI:0465(dip)|MI:0465(dip)|MI:0465(dip) DIP_54579|DIP_54557|DIP_54561 -|-|- -|-|- DDX58 MEX3C MI:0004(affinity chromatography technology) 24706898 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_310115 bait prey DDX58 MAVS MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0807(comigration in gel electrophoresis)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0493(in vivo)|MI:0663(confocal microscopy)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 16127453,16153868,16177806,17709747,19164550,19193793,19454348,20007272,20071582,20080758,20406818,20434986,21102435,21292167,21903422,22022264,22114345,22301138,22623778 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0914(association)|MI:0914(association) (intact)|(intact)|MI:0465(dip)|(biogrid)|(intact)|(intact)|MI:0465(dip)|(biogrid)|(biogrid)|(intact)|(biogrid)|(intact)|(intact)|(biogrid)|(biogrid)|(intact)|(biogrid)|(biogrid)|(intact)|MI:0468(hprd)|(intact)|(biogrid)|(biogrid)|(biogrid)|(intact)|(intact)|(biogrid)|MI:0465(dip)|(intact)|(intact) UniProt_115777|UniProt_172519|DIP_55477|BIOGRID_149439|UniProt_109935|UniProt_98289|DIP_54100|BIOGRID_153311|BIOGRID_155623|UniProt_120569|BIOGRID_155715|UniProt_98362|UniProt_98363|BIOGRID_255875|BIOGRID_147121|UniProt_120570|BIOGRID_158754|BIOGRID_214768|UniProt_102232|HPRD_31192|UniProt_122918|BIOGRID_211854|BIOGRID_160763|BIOGRID_153433|UniProt_81686|UniProt_120574|BIOGRID_158897|DIP_54561|UniProt_115769|UniProt_172511 bait|bait|-|bait|prey|bait|-|bait|prey|prey|bait|bait|prey|prey|bait|prey|bait|bait|prey|-|neutral component|bait|bait|prey|bait|prey|prey|-|prey|prey prey|prey|-|prey|bait|prey|-|prey|bait|bait|prey|prey|bait|bait|prey|bait|prey|prey|bait|-|neutral component|prey|prey|bait|prey|bait|bait|-|bait|bait DDX58 UBC MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17392790,17719635,18636086,19454348,19675569,19996094,20071582,21292167,21835791,21906983,21910972,22022264,22114345,23000965,23209422,23264040,23388719,23399697,23950712,24366338,24493797,24622840,24706898 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(intact)|(biogrid)|(biogrid)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_307967|BIOGRID_307966|BIOGRID_144931|UniProt_97826|BIOGRID_310069|BIOGRID_159316|MINT_39855|MINT_69148|BIOGRID_118751|BIOGRID_247865|BIOGRID_284780|BIOGRID_248576|BIOGRID_149438|BIOGRID_149732|BIOGRID_250053|BIOGRID_250805|BIOGRID_144792|BIOGRID_116650|BIOGRID_181406|BIOGRID_147120|BIOGRID_158753|BIOGRID_121845|BIOGRID_309412|BIOGRID_310116|BIOGRID_160761|BIOGRID_267541|BIOGRID_158896 bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|prey|bait|bait|bait|bait|bait|bait|prey|prey prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|bait|prey|prey|prey|prey|prey|prey|bait|bait DDX3X DDX58 MI:0018(two hybrid)|MI:0018(two hybrid) 20127681 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_104205|UniProt_104204 bait|prey prey|bait DDX58 STAT1 MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 24360797 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact) UniProt_131463|UniProt_131464|UniProt_131465|UniProt_131466 prey|bait|bait|prey bait|prey|prey|bait DDX58 CYLD MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0493(in vivo)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 18636086 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact)|MI:0468(hprd)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint) BIOGRID_116648|UniProt_97820|UniProt_97827|HPRD_33415|MINT_69141|MINT_69140|MINT_39847|MINT_39848 bait|bait|prey|-|prey|bait|bait|prey prey|prey|bait|-|bait|prey|prey|bait DDX58 TBK1 MI:0004(affinity chromatography technology) 23950712 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_284777 bait prey DDX58 USP21 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 24493797 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization) (biogrid)|(biogrid)|(biogrid) BIOGRID_307963|BIOGRID_307964|BIOGRID_307965 prey|bait|prey bait|prey|bait DDX58 PRKCA MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22114345 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_160769|BIOGRID_160764|BIOGRID_160767 prey|prey|bait bait|bait|prey DDX58 RBCK1 MI:0004(affinity chromatography technology) 21292167 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_158746 bait prey DDX58 TRIM32 MI:0004(affinity chromatography technology) 22745133 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_197369 prey bait DDX58 USP4 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 23388719 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_250051|BIOGRID_250052 prey|bait bait|prey DDX58 MBP MI:0096(pull down)|MI:0096(pull down) 23264040 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_248579|BIOGRID_248578 bait|prey prey|bait PRKRIR DDX58 MI:0096(pull down) 21910972 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_159314 bait prey DDX58 TRIM25 MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17392790,20071582,20406818,20818395,21292167,22114345,23209422,23264040,23950712 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) UniProt_184501|UniProt_108391|BIOGRID_121847|BIOGRID_121848|BIOGRID_248577|BIOGRID_153310|BIOGRID_121846|BIOGRID_284778|BIOGRID_248091|BIOGRID_158749|BIOGRID_160762|BIOGRID_158759|BIOGRID_147122|BIOGRID_153309 bait|bait|bait|prey|prey|prey|prey|bait|prey|prey|bait|bait|bait|bait prey|prey|prey|bait|bait|bait|bait|prey|bait|bait|prey|prey|prey|prey DDX58 IKBKE MI:0004(affinity chromatography technology) 23950712 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_284779 bait prey DDX58 IRF3 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16153868,18636086 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_116649|BIOGRID_214769 bait|bait prey|prey TSPAN6 DDX58 MI:0004(affinity chromatography technology) 22908223 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_209574 prey bait DDX58 IKBKG MI:0004(affinity chromatography technology) 23950712 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_284781 bait prey DDX58 USP3 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 24366338 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_310067|BIOGRID_310072 bait|prey prey|bait DDX58 NLRC5 MI:0004(affinity chromatography technology) 20434986 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_255873 prey bait DDX58 UBE2D2 MI:0004(affinity chromatography technology) 17719635 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_118754 prey bait DDX58 UBE2D1 MI:0004(affinity chromatography technology) 17719635 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_118753 prey bait

PPI - HINT Gene A Gene B PMID Method Quality DDX58 DDX58 18948594,21102435,21102435,17190814,18948594,23264040,21102435 0007,0807,0404,0007,0404,0096,0007 LC DDX58 ISG15 16009940,17719635 0004,0004 LC DDX58 UBC 19675569,18636086,20071582,18636086,21835791,19454348,17460044,21292167,22114345,23264040,22022264,21910972,20403326,17460044,19996094,17392790,17719635 0096,0004,0004,0007,0004,0004,0096,0004,0004,0096,0004,0004,0096,0007,0004,0004,0004 LC DDX58 TIA1 26344197 0401 HT DDX58 IKBKE 16281057,23950712 0007,0004 LC DDX58 TRIM25 17392790,20406818,20406818,19484123,20071582,17392790,17392790,21292167,27122586,22114345,18948594,23264040,23950712,20818395,17392790,17392790 0007,0007,0004,0004,0004,0096,0415,0004,0004,0004,0096,0096,0004,0096,0059,0004 LC DDX58 IRF3 20357099,18636086,16153868,16153868 0007,0004,0007,0004 LC DDX58 MAVS 17709747,22022264,20071582,21903422,22623778,17190814,21419663,19881509,20554965,26061460,20434986,16153868,21102435,18948594,16153868,16585524,22114345,16177806,18200010,20406818,16177806,20007272,22301138,21292167,16127453,18948594,16127453,18977754,19454348,20080758,21903422,20406818,18207245,21844353,17020950,16127453,22844514,19193793,19164550 0007,0004,0004,0007,0663,0007,0007,0007,0004,0004,0004,0004,0007,0007,0007,0007,0004,0007,0006,0004,0004,0006,0007,0004,0004,0096,0019,0007,0004,0006,0004,0007,0007,0006,0007,0007,0007,0007,0007 LC DDX58 TMEM173 18724357,18818105,18724357 0006,0007,0007 LC DDX58 RNF135 19484123,19017631,19484123,19484123,19017631,19017631,23950712,19484123,19017631 0415,0007,0004,0007,0018,0004,0004,0018,0415 LC DDX58 DHX58 17190814,17020950 0007,0007 LC DDX58 CYLD 18636086,18636086,18636086,18467330 0004,0007,0006,0007 LC DDX58 VAPA 26496610,26496610 0007,0004 HT DDX58 TBK1 16281057,21419663,23950712 0007,0007,0004 LC DDX58 TIA1 26344197 0401 HT DDX58 VAPA 26496610,26496610 0007,0004 HT DDX58 DDX58 18948594,21102435,21102435,17190814,18948594,23264040,21102435 0007,0807,0404,0007,0404,0096,0007 LC DDX58 ISG15 16009940,17719635 0004,0004 LC DDX58 UBC 19675569,18636086,20071582,18636086,21835791,19454348,17460044,21292167,22114345,23264040,22022264,21910972,20403326,17460044,19996094,17392790,17719635 0096,0004,0004,0007,0004,0004,0096,0004,0004,0096,0004,0004,0096,0007,0004,0004,0004 LC DDX58 IKBKE 16281057,23950712 0007,0004 LC DDX58 TRIM25 17392790,20406818,20406818,19484123,20071582,17392790,17392790,21292167,27122586,22114345,18948594,23264040,23950712,20818395,17392790,17392790 0007,0007,0004,0004,0004,0096,0415,0004,0004,0004,0096,0096,0004,0096,0059,0004 LC DDX58 IRF3 20357099,18636086,16153868,16153868 0007,0004,0007,0004 LC DDX58 MAVS 17709747,22022264,20071582,21903422,22623778,17190814,21419663,19881509,20554965,26061460,20434986,16153868,21102435,18948594,16153868,16585524,22114345,16177806,18200010,20406818,16177806,20007272,22301138,21292167,16127453,18948594,16127453,18977754,19454348,20080758,21903422,20406818,18207245,21844353,17020950,16127453,22844514,19193793,19164550 0007,0004,0004,0007,0663,0007,0007,0007,0004,0004,0004,0004,0007,0007,0007,0007,0004,0007,0006,0004,0004,0006,0007,0004,0004,0096,0019,0007,0004,0006,0004,0007,0007,0006,0007,0007,0007,0007,0007 LC DDX58 TMEM173 18724357,18818105,18724357 0006,0007,0007 LC DDX58 RNF135 19484123,19017631,19484123,19484123,19017631,19017631,23950712,19484123,19017631 0415,0007,0004,0007,0018,0004,0004,0018,0415 LC DDX58 DHX58 17190814,17020950 0007,0007 LC DDX58 CYLD 18636086,18636086,18636086,18467330 0004,0007,0006,0007 LC DDX58 TBK1 16281057,21419663,23950712 0007,0007,0004 LC DDX58 DDX58 18948594,25084375,21102435,21102435,24590070,18948594,20581823,21102435 0007,0114,0807,0404,0404,0404,0114,0007 LC DDX58 PRKCG 22114345 0415 LC DDX58 PRKCB 22114345,22114345 0415,0004 LC DDX58 UBC 24590070 0114 LC DDX58 PRKCA 22114345,22114345 0415,0004 LC DDX58 TIA1 26344197 0401 LC DDX58 UBE2D1 17719635 0415 LC DDX58 UBE2D3 17719635 0415 LC DDX58 UBE2K 17719635 0415 LC DDX58 UBE2D2 17719635 0415 LC DDX58 TRIM25 17392790,17392790,17392790,25172487,19675569,24478431,17392790,17392790 0007,0096,0415,0415,0415,0809,0059,0004 LC DDX58 ZC3HAV1 21102435,21102435,21102435,21102435,21102435 0107,0663,0055,0007,0006 LC DDX58 MAVS 24478431,19036819,16127453,16127453,16127453 0809,0055,0004,0019,0007 LC DDX58 RNF135 19484123,19017631,19484123,19484123,19017631,19017631,19484123,19017631 0415,0007,0004,0007,0018,0004,0018,0415 LC DDX58 USP3 24366338,24366338 0004,0415 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P61077 O95786 UBE2D3 DDX58 0.309 17719635 P61086 O95786 UBE2K DDX58 0.309 17719635 O95786 O43422 DDX58 PRKRIR 0.309 21910972 O95786 O15205 DDX58 UBD 0.376 26996158 Q9P0L0 O95786 VAPA DDX58 0.126 26496610 Q9Y6I4 O95786 USP3 DDX58 0.454 24366338 O95786 O94817 DDX58 ATG12 0.033 17709747 Q86WI3 O95786 NLRC5 DDX58 0.21 20434986 P02686 O95786 MBP DDX58 0.376 23264040 P05129 O95786 PRKCG DDX58 0.309 22114345 P05161 O95786 ISG15 DDX58 0.236 16009940 Q14164 O95786 IKBKE DDX58 0.21 23950712 O95786 O14879 DDX58 IFIT3 0.21 21813773 P03418 O95786 N DDX58 0.126 22623778 O95786 A1A4Y4 DDX58 IRGM 0.21 25891078 O95786 O95786 DDX58 DDX58 0.332 23264040 O95786 O43657 DDX58 TSPAN6 0.21 22908223 P17252 O95786 PRKCA DDX58 0.569 22114345 P05771 O95786 PRKCB DDX58 0.569 22114345 P0CG50 O95786 UBC DDX58 0.21 20818395 P12931 O95786 SRC DDX58 0.21 19419966 P42224 O95786 STAT1 DDX58 0.21 24360797 P31483 O95786 TIA1 DDX58 0.081 26344197 Q9BYM8 O95786 RBCK1 DDX58 0.21 21292167 Q5U5Q3 O95786 MEX3C DDX58 0.21 24706898 Q61510 O95786 TRIM25 DDX58 0.21 20818395 Q9UK80 O95786 USP21 DDX58 0.454 24493797 Q9UHD2 O95786 TBK1 DDX58 0.21 23950712 Q9Y6K9 O95786 IKBKG DDX58 0.21 23950712 Q9NQC7 O95786 CYLD DDX58 0.692 18636086 O95786 O08736 DDX58 CASP12 0.454 20818395 P0CG48 O95786 UBC DDX58 0.454 23264040,18636086 Q14653 O95786 IRF3 DDX58 0.376 16153868,18636086 Q9P0K7 O95786 RAI14 DDX58 0.236 21903422 Q9Y4E8 O95786 USP15 DDX58 0.454 26061460 Q9H1Y0 O95786 ATG5 DDX58 0.472 17709747 Q8IUD6 O95786 RNF135 DDX58 0.93 19017631,23950712,19484123 Q96S55 O95786 WRNIP1 DDX58 0.454 21903422 Q7Z434 O95786 MAVS DDX58 0.982 26061460,21292167,22114345,20080758,16127453,17709747,16153868,21903422,20406818,22623778,20434986,20554965,20071582,22022264,16177806,19454348 Q14258 O95786 TRIM25 DDX58 0.981 27122586,23264040,21292167,22114345,17392790,20071582,19675569,20406818,23950712,25172487 Q96EP0 O95786 RNF31 DDX58 0.376 21292167 P62837 O95786 UBE2D2 DDX58 0.309 17719635 Q13049 O95786 TRIM32 DDX58 0.21 22745133 Q13107 O95786 USP4 DDX58 0.376 23388719 P51668 O95786 UBE2D1 DDX58 0.309 17719635

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 IRGM DDX58 MI:0045 experimental interaction detection MI:0461 interaction database DDX3X DDX58 MI:0045 experimental interaction detection MI:0461 interaction database IFIT3 DDX58 MI:0045 experimental interaction detection MI:0461 interaction database IKBKB DDX58 MI:0362 inference MI:1106 pathways database UBE2L6 DDX58 MI:0362 inference MI:1106 pathways database CHUK DDX58 MI:0362 inference MI:1106 pathways database THAP12 DDX58 MI:0045 experimental interaction detection MI:0461 interaction database TSPAN6 DDX58 MI:0045 experimental interaction detection MI:0461 interaction database PRKRA DDX58 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 DDX58 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database DDX58 MYC MI:0045 experimental interaction detection MI:0461 interaction database DDX58 MBP MI:0045 experimental interaction detection MI:0461 interaction database DDX58 PRKCG MI:0045 experimental interaction detection MI:0461 interaction database DDX58 ISG15 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database DDX58 PRKCB MI:0045 experimental interaction detection MI:0461 interaction database DDX58 UBB MI:0362 inference MI:0461 interaction database DDX58 UBC MI:0045 experimental interaction detection MI:0461 interaction database DDX58 SRC MI:0045 experimental interaction detection MI:0461 interaction database DDX58 PRKCA MI:0045 experimental interaction detection MI:0461 interaction database DDX58 TAF1 MI:0045 experimental interaction detection MI:0461 interaction database DDX58 CBL MI:0362 inference MI:0461 interaction database DDX58 CDC25A MI:0362 inference MI:1106 pathways database DDX58 UBA7 MI:0362 inference MI:1106 pathways database DDX58 HNF4A MI:0045 experimental interaction detection MI:0461 interaction database DDX58 STAT1 MI:0045 experimental interaction detection MI:0461 interaction database DDX58 UBE2D1 MI:0045 experimental interaction detection MI:0461 interaction database DDX58 UBE2D3 MI:0045 experimental interaction detection MI:0461 interaction database DDX58 UBE2K MI:0045 experimental interaction detection MI:0461 interaction database DDX58 MAX MI:0045 experimental interaction detection MI:0461 interaction database DDX58 UBE2D2 MI:0045 experimental interaction detection MI:0461 interaction database DDX58 RPS27A MI:0362 inference MI:0461 interaction database DDX58 UBA52 MI:0362 inference MI:0461 interaction database DDX58 PTPN11 MI:0362 inference MI:0461 interaction database DDX58 TRIM26 MI:0045 experimental interaction detection MI:0461 interaction database DDX58 TRAF2 MI:0362 inference MI:1106 pathways database DDX58 TRIM32 MI:0045 experimental interaction detection MI:0461 interaction database DDX58 USP4 MI:0045 experimental interaction detection MI:0461 interaction database DDX58 TRAF3 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database DDX58 FADD MI:0362 inference MI:1106 pathways database DDX58 MAP3K1 MI:0362 inference MI:1106 pathways database DDX58 RIPK1 MI:0362 inference MI:1106 pathways database DDX58 IKBKE MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database DDX58 TRIM25 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database DDX58 IRF3 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database DDX58 CASP8 MI:0362 inference MI:1106 pathways database DDX58 PCBP2 MI:0362 inference MI:1106 pathways database DDX58 MEX3C MI:0045 experimental interaction detection MI:0461 interaction database DDX58 USP17L2 MI:0362 inference MI:1106 pathways database DDX58 CASP12 MI:0362 inference MI:0461 interaction database DDX58 ZC3HAV1 MI:0045 experimental interaction detection MI:0461 interaction database DDX58 MAVS MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database DDX58 NLRC5 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database DDX58 TMEM173 MI:0362 inference MI:0461 interaction database DDX58 RNF135 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database DDX58 DDX60 MI:0362 inference MI:0461 interaction database DDX58 TANK MI:0362 inference MI:1106 pathways database DDX58 CASP10 MI:0362 inference MI:1106 pathways database DDX58 IRF7 MI:0362 inference MI:1106 pathways database DDX58 DHX58 MI:0362 inference MI:0461 interaction database DDX58 RNF31 MI:0045 experimental interaction detection MI:0461 interaction database DDX58 RNF125 MI:0362 inference MI:0461 interaction database DDX58 OTUD5 MI:0362 inference MI:1106 pathways database DDX58 ITCH MI:0362 inference MI:1106 pathways database DDX58 SIGLEC10 MI:0362 inference MI:0461 interaction database DDX58 UBE2E2 MI:0362 inference MI:0461 interaction database DDX58 SIGLEC11 MI:0362 inference MI:0461 interaction database DDX58 WRNIP1 MI:0045 experimental interaction detection MI:0461 interaction database DDX58 SIKE1 MI:0362 inference MI:1106 pathways database DDX58 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database DDX58 IFIH1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database DDX58 ATG5 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database DDX58 CYLD MI:0045 experimental interaction detection MI:0461 interaction database DDX58 RAI14 MI:0045 experimental interaction detection MI:0461 interaction database DDX58 VAPA MI:0045 experimental interaction detection MI:0461 interaction database DDX58 ONECUT1 MI:0045 experimental interaction detection MI:0461 interaction database DDX58 RNF14 MI:0362 inference MI:0461 interaction database DDX58 TBK1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database DDX58 USP25 MI:0362 inference MI:1106 pathways database DDX58 HERC5 MI:0362 inference MI:1106 pathways database DDX58 USP21 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database DDX58 RCE1 MI:0362 inference MI:1106 pathways database DDX58 USP15 MI:0045 experimental interaction detection MI:0461 interaction database DDX58 TRAF6 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database DDX58 USP3 MI:0045 experimental interaction detection MI:0461 interaction database DDX58 IKBKG MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database