Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 19 44511389 rs2191566 G T rs2191566 4.00E-07 METHOTREXATE POLYGLUTAMIC ACID|ANTIMETABOLITES, ANTINEOPLASTIC|DOPA DECARBOXYLASE|MKL1 PROTEIN, HUMAN|IKAROS TRANSCRIPTION FACTOR|ARID5B PROTEIN, HUMAN|TRANSCRIPTION FACTORS|IKZF1 PROTEIN, HUMAN|ONCOGENE PROTEINS, FUSION|DNA-BINDING PROTEINS Acute lymphoblastic leukemia (childhood) HPOID:0006721 DOID:9952|DOID:12603 A,C intron GWASdb_drug 11 10534866 rs10770123 C T rs10770123 9.31E-04 Prostate cancer mortality HPOID:0012125 DOID:10283 C UTR-3 GWASdb_trait 11 10540343 rs1993819 A G rs1993819 4.96E-04 Prostate cancer mortality HPOID:0012125 DOID:10283 A intron GWASdb_trait 19 44511389 rs2191566 G T rs2191566 5.90E-04 Multiple complex diseases HPOID:0000118 NA A,C intron GWASdb_trait 19 44511389 rs2191566 G T rs2191566 4.00E-07 Acute lymphoblastic leukemia (childhood) HPOID:0006721 DOID:9952|DOID:12603 A,C intron GWASdb_trait 19 44511389 rs2191566 G T rs2191566 4.00E-07 Nasopharyngeal carcinoma HPOID:0100630 DOID:9261 A,C intron GWASdb_trait 19 44511589 rs454904 A G rs454904 6.72E-04 Multiple complex diseases HPOID:0000118 NA A intron GWASdb_trait

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000110315.6 RNF141 616641