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GP GP G G GP G G G GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G USP5 UBQLN3 23023127 pred G G G G G G GP G USP5 SUMO2 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G RPN1 USP5 21836163 pred G GP G G GP GP G GP GP G G GP GP GP G GP GP G GP G GP GP G GP GP GP GP GP G USP5 UBQLN4 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G USP5 USP15 23023127, 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G USP5 UBE4A 21836163 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP G GP GP G USP5 MIB1 23023127 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP G G GP G GP GP G USP5 OTUD7B 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G USP5 NEDD4 23023127 pred GP GP G GP P G GP GP GP G GP GP G GP GP GP GP G GP GP G GP GP GP GP P G USP5 UBE2D1 21836163 pred GP G G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP GP G GP G GP GP GP G PTPN4 USP5 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP G GP GP G GP GP G USP5 USP16 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP G GP GP GP GP GP G USP5 KAT2B 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G USP5 COPS8 21836163 pred G G G G G GP G GP G G G G GP G G G GP G G G G G G G G G G GP G WWP2 USP5 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP G GP GP G GP GP G ELANE USP5 23023127 pred G GP G G MDM4 USP5 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G USP5 PSMD4 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP G GP GP G GP GP G USP5 UBXN1 23023127 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G USP5 DDI2 23023127 pred P P P P P P P P P P P P P P UCHL1 USP5 23023127 pred G G G G G GP G G GP G GP G G G G G GP G GP G G G G G G G G GP G USP5 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G USP5 KLK5 23023127 pred G GP G G GP GP G GP P G GP GP G G G GP GP G GP G GP G G GP P P GP G USP5 USP25 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G USP5 UHRF2 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G AKT1 USP5 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G USP5 PHF20 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G TADA2A USP5 25402006 pred G G G G G G G G G G G G G G G G G G G G INS USP5 23023127 pred G GP G USP5 TBC1D26 23023127 pred P P P P P P P P P P P P P P P P P P P P GP USP5 TAF10 25402006, 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G USP5 UBE2G2 21836163 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP G G GP GP GP GP G USP5 USP49 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP G GP GP GP GP GP G USP5 UBXN2A 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G FABP1 USP5 23023127 pred GP GP GP GP G GP G USP5 HSPBP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP G GP GP GP GP GP G CBL USP5 23023127 pred G GP G G GP GP G G GP G GP G GP GP G G GP GP G G G G G G G GP G GP G CIDEA USP5 23023127 pred G G G G G G G G PSMC2 USP5 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G USP5 TRIM9 23023127 pred G G G G G G G G G G G USP5 XPC 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G USP5 FAF1 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G USP5 AMFR 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G TP53 USP5 25402006 pred G G G G G G G G G G G G G G G GP G G G G GP G G G GP G G GP G USP5 TNRC6C 23023127 pred G G G G GP G G G GP G G G G GP G P G G GP G P G G G GP GP GP GP G USP5 UBXN2B 23023127 pred G GP G G G G G G GP G GP G GP G G GP G GP G G G GP G G GP G GP GP G USP5 RBBP6 23023127 pred GP G G G G GP G GP GP G GP GP GP G G GP GP G G G GP G G G GP GP GP GP G PSMD14 USP5 25402006, 21836163 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G G GP GP G GP GP G USP5 RNF2 23023127 pred P P P P GP P P P P P P P P P P P USP5 CSNK1D 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G USP5 USP14 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G USP5 HUWE1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G IGF1 USP5 23023127 pred G G G G GP G G G G G G G G G G G G G G G G G G G G G GP G USP5 YOD1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G GP GP G GP GP GP GP GP G USP5 LATS2 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP G GP GP G USP8 USP5 23023127 pred G GP G G GP GP G G GP G GP G GP G G GP GP G GP G GP GP G GP GP G GP GP G PTPN3 USP5 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP G GP GP P GP GP G USP5 ARIH1 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G USP5 UBE2K 23023127, 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G PARK2 USP5 23023127 pred P GP G P GP G GP GP G GP P P G P GP GP P G P G GP GP P GP G USP5 POLDIP3 23023127 pred G GP G G GP GP G GP GP G GP GP GP GP G GP GP GP G G G G G GP GP G GP GP G USP5 USP20 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G USP5 PRPF19 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G USP5 TAF9 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G USP5 NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G USP5 USP7 25402006, 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G USP5 SUMO4 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G G GP GP GP G GP GP G GP G GP GP GP G USP5 SENP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G TRIM21 USP5 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G USP5 HDAC6 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP G GP GP GP GP GP G USP5 PIAS4 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G USP5 RNF5 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP G GP GP G GP GP G USP5 RNF220 23023127 pred G GP G G GP GP G G GP G GP GP GP G G G GP G GP G GP GP G GP G G GP G G USP5 PSMC1 21836163 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP G G GP GP GP GP G USP5 DDI1 23023127 pred P P P P G GP GP P G P P GP PSMD3 USP5 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G LATS1 USP5 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP G GP GP G USP5 NEDD4L 23023127 pred GP GP G GP G GP GP G GP G GP P G GP GP GP GP G GP GP G G GP G GP G USP5 CUL4B 21836163 pred GP GP G G GP GP G GP GP G GP GP G GP G GP GP G GP G GP GP G GP GP GP GP GP G USP5 NSFL1C 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G G GP GP GP GP G USP5 UBC 23023127 pred USP5 SENP2 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G USP5 USP44 23023127 pred P P P P P P P P P P P P P GP G P P P P P GP USP5 TRIM33 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP G G GP GP GP GP G USP5 RNF41 23023127 pred GP GP G G G GP G GP GP G GP P G G GP GP P P G P G GP GP GP GP P PSMC3 USP5 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G USP5 UBQLN2 23023127, 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G USP5 GABARAPL2 23023127 pred G GP G G GP GP G GP GP G GP G G G G GP GP G GP G G GP G G GP G GP GP G USP5 BAG6 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G UBL4A USP5 23023127 pred GP GP G G G GP G G GP G GP G G G G G GP G GP G GP G G G G G GP P G USP5 COPS5 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G PIK3CA USP5 23023127 pred GP GP G P GP G GP GP G GP GP GP GP G P GP GP GP G P GP G GP GP GP GP GP USP5 ITCH 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G UBA7 USP5 21836163 pred P P P P P P P P P P P P P P P P P PSMD11 USP5 21836163 pred G GP G G GP GP G GP GP G GP G GP G G G GP G G G GP G G G G G G GP G USP5 UBL4B 23023127 pred P P P P P P P P P P P P P P P P P P P USP5 MAPK15 23023127 pred GP GP G G G GP GP GP G GP GP GP P GP GP P GP G GP P G GP GP GP GP G USP5 UBASH3A 23023127 pred P P G P P P G USP5 PRKCQ 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G USP5 SUMO1 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P45974 P62987 pull down 16007098 direct interaction X 2 Q8WW34 P45974 two hybrid prey pooling approach 25416956 physical association X 2 Q8WW34 P45974 two hybrid array 25416956 physical association X 2 Q8WW34 P45974 validated two hybrid 25416956 physical association X 2 P45974 Q9Y3C5 two hybrid 15231748 physical association X 2 P45974 P54727 pull down 16712842 physical association X 2 P45974 P54727 pull down 16712842 physical association X 2 P45974 A0A024RBN1 anti bait coimmunoprecipitation 17353931 physical association X 2 P45974 P0CG48 enzymatic study 19373254 deubiquitination reaction X 2 O14641 P45974 two hybrid pooling approach 16189514 physical association X 2 O75528 P45974 pull down 16189514 physical association X 2 O75528 P45974 two hybrid pooling approach 16189514 physical association X 2 Q9UBN6 P45974 anti bait coimmunoprecipitation 17353931 physical association X 2 P45974 Q92995 anti tag coimmunoprecipitation 19615732 physical association X 2 P45974 A0A024R110 two hybrid prey pooling approach 25416956 physical association X 2 P45974 A0A024R110 two hybrid array 25416956 physical association X 2 P45974 A0A024R110 validated two hybrid 25416956 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B USP5 PMS1 MI:0004(affinity chromatography technology) 17148452 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_122102 prey bait USP5 CLNS1A MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304875 prey bait USP5 RAD23B MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down) 16712842 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|MI:0471(mint)|(intact)|MI:0471(mint)|(biogrid)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(intact) UniProt_200122|UniProt_167479|UniProt_84978|UniProt_200131|MINT_49535|UniProt_167488|MINT_81736|BIOGRID_226275|MINT_49528|MINT_81743|BIOGRID_226270|UniProt_84987 prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait USP5 RAD23A MI:0401(biochemical)|MI:0415(enzymatic study) 19013454,22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_302871|BIOGRID_188742 bait|prey prey|bait TXNL1 USP5 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_236764 bait prey ATP6V1A USP5 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_242577 prey bait USP5 UBR1 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_236499 bait prey USP5 UBE2S MI:0415(enzymatic study) 20622874 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_165029 bait prey USP5 TNFRSF10D MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_145037 prey bait USP5 TXNDC17 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_238574 prey bait OXSR1 USP5 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304878 bait prey USP5 TRIM5 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248189 bait prey USP5 TRIM55 MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_223022 prey bait USP5 TRIM54 MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_223039 prey bait USP5 NT5C2 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304877 prey bait USP5 MCTS1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304876 prey bait USP5 URM1 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_237473 bait prey USP5 THTPA MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_236128 prey bait WARS USP5 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304960 prey bait USP5 CDC34 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_298965 bait prey DVL2 USP5 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0468(hprd)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(intact) HPRD_21719|MINT_36782|MINT_65936|BIOGRID_78724|UniProt_151581 -|bait|bait|bait|unspecified role -|prey|prey|prey|unspecified role USP5 UBP1 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_240015 prey bait USP5 XIAP MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_237777 bait prey CCT6A USP5 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_242471 bait prey KDM5C USP5 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_242910 bait prey USP5 RAD18 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 24454762 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_309264|BIOGRID_309263 bait|prey prey|bait USP5 SIRT7 MI:0004(affinity chromatography technology) 22586326 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_189694 prey bait PLA2G2A USP5 MI:0415(enzymatic study) 22118674 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_160305 prey bait APP USP5 MI:0096(pull down) 21832049 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_229202 prey bait USP5 USP13 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119998|UniProt_100683 bait|bait prey|prey USP5 TRIM39 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248188 bait prey USP5 UBE2H MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_243467 prey bait USP5 RNF11 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid) 15231748,23751493 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0471(mint)|MI:0468(hprd)|(intact)|(biogrid)|(biogrid)|MI:0471(mint) MINT_31420|HPRD_37394|UniProt_78509|BIOGRID_282474|BIOGRID_259412|MINT_60185 prey|-|prey|prey|prey|prey bait|-|bait|bait|bait|bait USP5 PRKAB1 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_149618 prey bait USP5 TRAF6 MI:0415(enzymatic study) 20622874 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_165044 bait prey USP5 TWF1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304880 prey bait USP5 UBA5 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_236230 prey bait TADA3 USP5 MI:0018(two hybrid)|MI:0096(pull down)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(intact)|(intact)|MI:0468(hprd)|(biogrid)|MI:0471(mint)|(biogrid) MINT_40205|UniProt_153947|UniProt_82523|HPRD_21720|BIOGRID_81124|MINT_69578|BIOGRID_81393 prey|unspecified role|bait|-|prey|prey|prey bait|unspecified role|prey|-|bait|bait|bait UCHL3 USP5 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_238272 prey bait USP5 TRIM26 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248187 bait prey PSMA3 USP5 MI:0004(affinity chromatography technology) 22079093 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_156034 bait prey USP5 GNPDA1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_300002 bait prey USP5 PJA1 MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_222982 prey bait USP5 HERC4 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_300144 bait prey UBC USP5 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0096(pull down)|MI:0686(unspecified method)|MI:0415(enzymatic study)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0114(x-ray crystallography)|MI:0004(affinity chromatography technology)|MI:0096(pull down) 10,15852347,16007098,16196087,17980597,18482987,18781797,19285159,19373254,20622874,20639865,21139048,21890473,21906983,21963094,21987572,22053931,22118674,22216260,22428841,22505724,22878415,23000965,23287719,23314748,8841133 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0204(deubiquitination reaction)|MI:0204(deubiquitination reaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0204(deubiquitination reaction)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0471(mint)|(intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0471(mint)|(biogrid)|(biogrid) BIOGRID_190907|BIOGRID_158845|BIOGRID_225202|BIOGRID_197618|BIOGRID_166473|BIOGRID_270451|BIOGRID_142937|BIOGRID_200659|BIOGRID_178270|BIOGRID_160208|BIOGRID_168940|MINT_74132|UniProt_100028|BIOGRID_196826|BIOGRID_249557|BIOGRID_163209|BIOGRID_160897|BIOGRID_160898|BIOGRID_117761|BIOGRID_247917|BIOGRID_165015|BIOGRID_175183|BIOGRID_220639|BIOGRID_208443|BIOGRID_160379|BIOGRID_222405|MINT_43920|BIOGRID_161972|BIOGRID_117688 prey|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|neutral component|neutral component|prey|prey|bait|prey|bait|bait|bait|prey|bait|prey|bait|bait|bait|neutral component|bait|prey bait|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|neutral component|neutral component|bait|bait|prey|bait|prey|prey|prey|bait|prey|bait|prey|prey|prey|neutral component|prey|bait PCNA USP5 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_301793 prey bait USP5 RFFL MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_222970 prey bait P4HB USP5 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_301644 prey bait USP5 TRIML1 MI:0096(pull down)|MI:0096(pull down) 19156909 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_192198|BIOGRID_192199 prey|bait bait|prey USP5 TRIM63 MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_222997 prey bait USP5 PSME1 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_240283 prey bait USP5 TCEAL4 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304311 bait prey USP5 PRDX1 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_238984 prey bait USP5 PBK MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_239145 prey bait USP5 ZFP91 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_237023 bait prey USP5 IPO9 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_300627 bait prey USP5 TRNT1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304879 prey bait USP5 SUMO2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19471022,21252943 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_183988|BIOGRID_183445 prey|prey bait|bait USP5 USP28 MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_223112 prey bait ZNF593 USP5 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_236502 prey bait

PPI - HINT Gene A Gene B PMID Method Quality ZNF593 USP5 22939629 0401 HT OXSR1 USP5 22863883 0401 HT P4HB USP5 22863883 0401 HT UBC USP5 16007098,17550899,25970461,22428841,18482987,23314748,22878415,24424410,17980597,8841133,16564012,22216260,19285159,16564012,22216260 0096,0004,0096,0096,0096,0096,0096,0096,0004,0096,0114,0096,0096,0096,0415 LC PCNA USP5 22863883 0401 HT UCHL3 USP5 22939629 0401 HT WARS USP5 22863883 0401 HT AGL USP5 26344197 0401 HT ATP6V1A USP5 22939629 0401 HT CCT6A USP5 22939629 0401 HT KDM5C USP5 22939629 0401 HT USP5 GNPDA1 22863883 0401 HT USP5 CDC34 22863883 0401 HT USP5 NT5C2 22863883 0401 HT USP5 CLNS1A 22863883 0401 HT USP5 RAD23A 19013454,22863883 0004,0401 LC,HT USP5 UBE2H 22939629 0401 HT USP5 XIAP 22939629 0401 HT USP5 PRDX1 22939629 0401 HT USP5 TWF1 22863883 0401 HT USP5 LAGE3 26344197 0401 HT USP5 Q59EG3 26344197 0401 HT USP5 HERC4 22863883 0401 HT USP5 Q86SZ9 22939629 0401 HT USP5 UBR1 22939629 0401 HT USP5 USP13 19615732,19615732 0004,0007 HT USP5 TCEAL4 22863883 0401 HT USP5 ZFP91 22939629 0401 HT USP5 CEP19 26638075,26638075 1314,1313 HT USP5 IPO9 22863883 0401 HT USP5 TRNT1 22863883 0401 HT USP5 TXNDC17 22939629 0401 HT USP5 URM1 22939629 0401 HT USP5 THTPA 22939629 0401 HT USP5 YTHDF1 26344197 0401 HT USP5 UBA5 22939629 0401 HT USP5 TMOD3 26344197 0401 HT USP5 UBP1 22939629 0401 HT USP5 TNFRSF10D 17353931 0006 HT USP5 MCTS1 22863883 0401 HT USP5 STUB1 26344197 0401 HT USP5 PRKAB1 17353931 0006 HT USP5 YTHDF2 26344197 0401 HT USP5 HEL-S-114 22939629 0401 HT USP5 HEL164 22939629 0401 HT ZNF593 USP5 22939629 0401 HT OXSR1 USP5 22863883 0401 HT P4HB USP5 22863883 0401 HT PCNA USP5 22863883 0401 HT UCHL3 USP5 22939629 0401 HT WARS USP5 22863883 0401 HT AGL USP5 26344197 0401 HT ATP6V1A USP5 22939629 0401 HT CCT6A USP5 22939629 0401 HT KDM5C USP5 22939629 0401 HT USP5 GNPDA1 22863883 0401 HT USP5 CDC34 22863883 0401 HT USP5 NT5C2 22863883 0401 HT USP5 CLNS1A 22863883 0401 HT USP5 RAD23A 22863883 0401 HT USP5 UBE2H 22939629 0401 HT USP5 XIAP 22939629 0401 HT USP5 PRDX1 22939629 0401 HT USP5 TWF1 22863883 0401 HT USP5 LAGE3 26344197 0401 HT USP5 Q59EG3 26344197 0401 HT USP5 HERC4 22863883 0401 HT USP5 Q86SZ9 22939629 0401 HT USP5 UBR1 22939629 0401 HT USP5 USP13 19615732,19615732 0004,0007 HT USP5 TCEAL4 22863883 0401 HT USP5 ZFP91 22939629 0401 HT USP5 CEP19 26638075,26638075 1314,1313 HT USP5 IPO9 22863883 0401 HT USP5 TRNT1 22863883 0401 HT USP5 TXNDC17 22939629 0401 HT USP5 URM1 22939629 0401 HT USP5 THTPA 22939629 0401 HT USP5 YTHDF1 26344197 0401 HT USP5 UBA5 22939629 0401 HT USP5 TMOD3 26344197 0401 HT USP5 UBP1 22939629 0401 HT USP5 TNFRSF10D 17353931 0006 HT USP5 MCTS1 22863883 0401 HT USP5 STUB1 26344197 0401 HT USP5 PRKAB1 17353931 0006 HT USP5 YTHDF2 26344197 0401 HT USP5 HEL-S-114 22939629 0401 HT USP5 HEL164 22939629 0401 HT UBC USP5 16007098,17550899,25970461,22428841,18482987,23314748,22878415,24424410,17980597,8841133,16564012,22216260,19285159,16564012,22216260 0096,0004,0096,0096,0096,0096,0096,0096,0004,0096,0114,0096,0096,0096,0415 LC USP5 RAD23A 19013454 0004 LC ZNF593 USP5 22939629 0401 LC DVL2 USP5 16189514,16189514 0398,0018 HT TADA3 USP5 16189514,16189514,16189514,16189514 0004,0398,0096,0018 HT OXSR1 USP5 22863883 0401 LC P4HB USP5 22863883 0401 LC UBC USP5 20622874,19373254,27066941,PDB_3IHP,26876099,16564012,22216260,16564012,22216260 0415,0415,0415,0114,0415,0114,0096,0096,0415 LC PCNA USP5 22863883 0401 LC PLA2G2A USP5 22118674 0415 LC UCHL3 USP5 22939629 0401 LC WARS USP5 22863883 0401 LC AGL USP5 26344197 0401 LC ATP6V1A USP5 22939629 0401 LC CCT6A USP5 22939629 0401 LC KDM5C USP5 22939629 0401 LC USP5 USP5 PDB_3IHP,16564012 0114,0114 LC USP5 GNPDA1 22863883 0401 LC USP5 CDC34 22863883 0401 LC USP5 NT5C2 22863883 0401 LC USP5 CLNS1A 22863883 0401 LC USP5 RAD23A 22863883 0401 LC USP5 UBE2H 22939629 0401 LC USP5 XIAP 22939629 0401 LC USP5 PRDX1 22939629 0401 LC USP5 TWF1 22863883 0401 LC USP5 TRIM26 23105109 0018 LC USP5 LAGE3 26344197 0401 LC USP5 DAZAP2 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT USP5 UBE2S 20622874 0415 LC USP5 Q59EG3 26344197 0401 LC USP5 HERC4 22863883 0401 LC USP5 Q86SZ9 22939629 0401 LC USP5 UBR1 22939629 0401 LC USP5 PJA1 22626734 0415 HT USP5 UBTD2 25207809,25207809,25207809 0004,0114,0096 LC USP5 TMEM239 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT USP5 RFFL 22626734 0415 HT USP5 TRIM63 22626734 0415 HT USP5 TCEAL4 22863883 0401 LC USP5 ZFP91 22939629 0401 LC USP5 IPO9 22863883 0401 LC USP5 TRNT1 22863883 0401 LC USP5 USP28 22626734 0415 HT USP5 TXNDC17 22939629 0401 LC USP5 URM1 22939629 0401 LC USP5 THTPA 22939629 0401 LC USP5 YTHDF1 26344197 0401 LC USP5 TRIM54 22626734 0415 HT USP5 TRIM55 22626734 0415 HT USP5 TRIM5 23105109 0018 LC USP5 UBA5 22939629 0401 LC USP5 SMURF1 20804422 0415 LC USP5 TRIM39 23105109 0018 LC USP5 TMOD3 26344197 0401 LC USP5 UBP1 22939629 0401 LC USP5 MCTS1 22863883 0401 LC USP5 STUB1 26344197 0401 LC USP5 RNF11 15231748 0018 HT USP5 TRAF6 20622874 0415 LC USP5 YTHDF2 26344197 0401 LC USP5 HEL-S-114 22939629 0401 LC USP5 HEL164 22939629 0401 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P45974 O43396 USP5 TXNL1 0.081 22939629 P62256 P45974 UBE2H USP5 0.081 22939629 Q9HCE1 P45974 MOV10 USP5 0.126 22658674 Q8NG27 P45974 PJA1 USP5 0.183 22626734 Q9GZZ9 P45974 UBA5 USP5 0.081 22939629 Q9NRC8 P45974 SIRT7 USP5 0.126 22586326 Q9NZI7 P45974 UBP1 USP5 0.081 22939629 P45974 P25788 USP5 PSMA3 0.126 22079093 P45974 P0CG63 USP5 UBI4 0.309 15096053 P45974 P04629 USP5 NTRK1 0.126 25921289 P45974 O95747 USP5 OXSR1 0.081 22863883 Q96LK0 P45974 CEP19 USP5 0.236 26638075 Q9BYT3 P45974 STK33 USP5 0.454 22451720 Q92995 P45974 USP13 USP5 0.236 19615732 Q9BZR9 P45974 TRIM8 USP5 0.236 unassigned1304 Q9NWF9 P45974 RNF216 USP5 0.236 unassigned1304 P45974 O95180 USP5 CACNA1H 0.454 25889575 Q8WW34 P45974 TMEM239 USP5 0.583 25416956,unassigned1304 Q9Y3C5 P45974 RNF11 USP5 0.472 15231748,23751493 P45974 O75528 USP5 TADA3 0.454 16189514 P45974 P0CG48 USP5 UBC 0.999 17550899,8841133,17980597,16564012,16007098,23287719,24424410,27066941,22216260,18482987,20622874,25970461,22428841,19373254,22878415,23314748,26876099,19285159 Q969Q1 P45974 TRIM63 USP5 0.183 22626734 Q8WZ73 P45974 RFFL USP5 0.183 22626734 Q96J02 P45974 ITCH USP5 0.126 26508657 Q96KB5 P45974 PBK USP5 0.081 22939629 Q9BRA2 P45974 TXNDC17 USP5 0.081 22939629 Q96Q11 P45974 TRNT1 USP5 0.081 22863883 Q9BU02 P45974 THTPA USP5 0.081 22939629 Q96RU2 P45974 USP28 USP5 0.183 22626734 Q9BYV2 P45974 TRIM54 USP5 0.183 22626734 Q9BYV6 P45974 TRIM55 USP5 0.183 22626734 Q9UBN6 P45974 TNFRSF10D USP5 0.236 17353931 Q9UBU9 P45974 NXF1 USP5 0.126 22658674 Q9ULC4 P45974 MCTS1 USP5 0.081 22863883 Q9UNE7 P45974 STUB1 USP5 0.081 26344197 P45974 P40227 USP5 CCT6A 0.081 P45974 P40692 USP5 MLH1 0.081 26344197 P45974 O00488 USP5 ZNF593 0.081 22939629 P45974 O14641 USP5 DVL2 0.286 16189514 P45974 P05067 USP5 APP 0.183 21832049 P45974 P07237 USP5 P4HB 0.081 22863883 P45974 P12004 USP5 PCNA 0.081 22863883 P45974 P14555 USP5 PLA2G2A 0.309 22118674 P45974 P15374 USP5 UCHL3 0.081 22939629 P45974 P22314 USP5 UBA1 0.21 25207809 P45974 P23381 USP5 WARS 0.081 22863883 P45974 P35573 USP5 AGL 0.081 26344197 P45974 P38606 USP5 ATP6V1A 0.081 P46926 P45974 GNPDA1 USP5 0.081 22863883 P49427 P45974 CDC34 USP5 0.081 22863883 P54727 P45974 RAD23B USP5 0.332 16712842 P98170 P45974 XIAP USP5 0.081 22939629 Q08050 P45974 FOXM1 USP5 0.376 26912724 Q12899 P45974 TRIM26 USP5 0.183 23105109 Q14657 P45974 LAGE3 USP5 0.081 26344197 Q16763 P45974 UBE2S USP5 0.309 20622874 Q5GLZ8 P45974 HERC4 USP5 0.081 22863883 Q8IWV7 P45974 UBR1 USP5 0.081 22939629 Q8N9V2 P45974 TRIML1 USP5 0.454 19156909 Q8WUN7 P45974 UBTD2 USP5 0.702 25207809 Q96EI5 P45974 TCEAL4 USP5 0.081 22863883 Q96JP5 P45974 ZFP91 USP5 0.081 22939629 Q96P70 P45974 IPO9 USP5 0.081 22863883 Q9BTM9 P45974 URM1 USP5 0.081 22939629 Q9BYJ9 P45974 YTHDF1 USP5 0.081 26344197 Q9C035 P45974 TRIM5 USP5 0.183 23105109 Q9HCE7 P45974 SMURF1 USP5 0.49 20804422,27133717 Q9HCM9 P45974 TRIM39 USP5 0.183 23105109 Q9NS91 P45974 RAD18 USP5 0.376 24454762 Q9NYL9 P45974 TMOD3 USP5 0.081 26344197 Q9Y478 P45974 PRKAB1 USP5 0.236 17353931 Q9Y4K3 P45974 TRAF6 USP5 0.309 20622874 Q9Y5A9 P45974 YTHDF2 USP5 0.081 26344197 P45974 P41229 USP5 KDM5C 0.081 22939629 Q12792 P45974 TWF1 USP5 0.081 22863883 P49902 P45974 NT5C2 USP5 0.081 22863883 Q15038 P45974 DAZAP2 USP5 0.454 25416956 Q06323 P45974 PSME1 USP5 0.081 22939629 Q06830 P45974 PRDX1 USP5 0.081 22939629 P54105 P45974 CLNS1A USP5 0.081 22863883 P54277 P45974 PMS1 USP5 0.126 17148452 P54725 P45974 RAD23A USP5 0.126 19013454

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 EIF3CL USP5 MI:0362 inference MI:0461 interaction database PSMD14 USP5 MI:0362 inference MI:0461 interaction database FBP2 USP5 MI:0362 inference MI:0461 interaction database DVL2 USP5 MI:0045 experimental interaction detection MI:0461 interaction database DDX3Y USP5 MI:0362 inference MI:0461 interaction database TADA3 USP5 MI:0045 experimental interaction detection MI:0461 interaction database EED USP5 MI:0362 inference MI:0461 interaction database CACNA1H USP5 MI:0045 experimental interaction detection MI:0461 interaction database PGLS USP5 MI:0362 inference MI:0461 interaction database MOCS3 USP5 MI:0362 inference MI:0461 interaction database NTRK1 USP5 MI:0045 experimental interaction detection MI:0461 interaction database APP USP5 MI:0045 experimental interaction detection MI:0461 interaction database ISG15 USP5 MI:0362 inference MI:0461 interaction database RPLP0 USP5 MI:0362 inference MI:0461 interaction database MYL1 USP5 MI:0362 inference MI:0461 interaction database FBP1 USP5 MI:0362 inference MI:0461 interaction database UBB USP5 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database UBC USP5 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database HSPA1B USP5 MI:0362 inference MI:0461 interaction database HSPA8 USP5 MI:0362 inference MI:0461 interaction database TOP1 USP5 MI:0362 inference MI:0461 interaction database PABPC1 USP5 MI:0362 inference MI:0461 interaction database PLA2G2A USP5 MI:0045 experimental interaction detection MI:0461 interaction database ATP6V1B1 USP5 MI:0362 inference MI:0461 interaction database HSPA6 USP5 MI:0362 inference MI:0461 interaction database ATP6V1B2 USP5 MI:0362 inference MI:0461 interaction database GPD1 USP5 MI:0362 inference MI:0461 interaction database UBA1 USP5 MI:0045 experimental interaction detection MI:0461 interaction database PSMA3 USP5 MI:0045 experimental interaction detection MI:0461 interaction database HSPA1L USP5 MI:0362 inference MI:0461 interaction database RPL4 USP5 MI:0362 inference MI:0461 interaction database HNF4A USP5 MI:0045 experimental interaction detection MI:0461 interaction database IARS USP5 MI:0362 inference MI:0461 interaction database USP5 RPL5 MI:0362 inference MI:0461 interaction database USP5 MTNR1A MI:0362 inference MI:0461 interaction database USP5 IST1 MI:0362 inference MI:0461 interaction database USP5 PMS1 MI:0045 experimental interaction detection MI:0461 interaction database USP5 HSPA2 MI:0362 inference MI:0461 interaction database USP5 RAD23A MI:0045 experimental interaction detection MI:0461 interaction database USP5 RAD23B MI:0045 experimental interaction detection MI:0461 interaction database USP5 SUMO2 MI:0045 experimental interaction detection MI:0461 interaction database USP5 RPS27A MI:0362 inference MI:0461,MI:1106 interaction database,pathways database USP5 UBA52 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database USP5 RBL2 MI:0045 experimental interaction detection MI:0461 interaction database USP5 TRIM26 MI:0045 experimental interaction detection MI:0461 interaction database USP5 PABPC4 MI:0362 inference MI:0461 interaction database USP5 DAZAP2 MI:0045 experimental interaction detection MI:0461 interaction database USP5 E2F4 MI:0045 experimental interaction detection MI:0461 interaction database USP5 UBE2S MI:0045 experimental interaction detection MI:0461 interaction database USP5 PABPC1L MI:0362 inference MI:0461 interaction database USP5 PABPC1L2A MI:0362 inference MI:0461 interaction database USP5 GPD1L MI:0362 inference MI:0461 interaction database USP5 TRIML1 MI:0045 experimental interaction detection MI:0461 interaction database USP5 PJA1 MI:0045 experimental interaction detection MI:0461 interaction database USP5 UBTD2 MI:0045 experimental interaction detection MI:0461 interaction database USP5 LEO1 MI:0362 inference MI:0461 interaction database USP5 TMEM239 MI:0045 experimental interaction detection MI:0461 interaction database USP5 RFFL MI:0045 experimental interaction detection MI:0461 interaction database USP5 RAD54L MI:0362 inference MI:0461 interaction database USP5 USP13 MI:0045 experimental interaction detection MI:0461 interaction database USP5 USP7 MI:0362 inference MI:0461 interaction database USP5 TOP1MT MI:0362 inference MI:0461 interaction database USP5 TRIM63 MI:0045 experimental interaction detection MI:0461 interaction database USP5 PABPC5 MI:0362 inference MI:0461 interaction database USP5 ITCH MI:0045 experimental interaction detection MI:0461 interaction database USP5 CEP19 MI:0045 experimental interaction detection MI:0461 interaction database USP5 USP28 MI:0045 experimental interaction detection MI:0461 interaction database USP5 EIF3C MI:0362 inference MI:0461 interaction database USP5 STK33 MI:0045 experimental interaction detection MI:0461 interaction database USP5 TRIM54 MI:0045 experimental interaction detection MI:0461 interaction database USP5 TRIM55 MI:0045 experimental interaction detection MI:0461 interaction database USP5 TRIM5 MI:0045 experimental interaction detection MI:0461 interaction database USP5 PABPC3 MI:0362 inference MI:0461 interaction database USP5 MOV10 MI:0045 experimental interaction detection MI:0461 interaction database USP5 SMURF1 MI:0045 experimental interaction detection MI:0461 interaction database USP5 TRIM39 MI:0045 experimental interaction detection MI:0461 interaction database USP5 SIRT7 MI:0045 experimental interaction detection MI:0461 interaction database USP5 RAD18 MI:0045 experimental interaction detection MI:0461 interaction database USP5 TNFRSF10D MI:0045 experimental interaction detection MI:0461 interaction database USP5 NXF1 MI:0045 experimental interaction detection MI:0461 interaction database USP5 RNF11 MI:0045 experimental interaction detection MI:0461 interaction database USP5 PRKAB1 MI:0045 experimental interaction detection MI:0461 interaction database USP5 TRAF6 MI:0045 experimental interaction detection MI:0461 interaction database