DNA & RNA Element - UTRdb Gene Name Type ASPicDB UTRaspic Refseq ID Genome SPSB2 3'UTR c0b3dc189e BA103617 NM_001146316 chr12:6850360-6852325:- SPSB2 3'UTR 5c19291a29 BA103618 NM_001146316 chr12:6850360-6852325:- SPSB2 5'UTR c0b3dc189e CA163227 NM_001146316 chr12:6850618-6852713:- SPSB2 5'UTR 5c19291a29 CA163228 NM_001146316 chr12:6850618-6852710:-

DNA & RNA Element - circBase circRNA ID Chrom Start End Strand hsa_circ_0025281 chr12 6980099 6982449 -

DNA & RNA Element - CircNet Circ ID GITPosition Express Symbol Entrez Category Strand Refered Name hsa-circ-SPSB2-overlap.4 NM_001319670Tchr12:6981827-6982150 expressed SPSB2 84727 protein-coding - hsa_circ_0099119 hsa-circ-SPSB2.1 NM_001146316Tchr12:6980099-6982449 none SPSB2 84727 protein-coding - hsa_circ_0025281

DNA & RNA Element - TRANSFAC Accession AS Description Species Entrez Pubmed Binding Info G035378 SPSB2 Homo sapiens 84727

DNA & RNA Element - TargetScan Gene Name UTR Region Start UTR Region End AIR Total Normalized 3P-seq-tags & Pseudocounts Strand hg19_chromosome Genome Start Genome End SPSB2; GRCC9; SSB2 1 253 100 189.408 - chr12 6980102 6980355 SPSB2; GRCC9; SSB2 254 255 94.778 189.408 - chr12 6980100 6980102 SPSB2; GRCC9; SSB2 256 257 2.645 189.408 - chr12 6980098 6980100

DNA & RNA Element - RepTar Gene Name miRNA Begin End Profile SPSB2 hsa-miR-519e beg:57 end:71 pic:3' TTGTGAGATTTTCCTCCGTGAA 5'& ..||||||||| &5' ----------GGGGAGGCACT- 3' SPSB2 hsa-miR-1224-3p beg:49 end:64 pic:3' GACTCCTCTCTCCTCCACCCC 5'& |.|||||||||| &5' ---------GGGGAGGTGGGG 3' SPSB2 kshv-miR-K12-10astar beg:119 end:130 pic:3' TCACCACCATAGCGGGGTTCGG 5'& |||||||. &5' --------------CCCAAGCT 3' SPSB2 hsa-miR-220c beg:0 end:9 pic:3' TCAGAAGTGTTGTCGGGACACA 5'& |||||||| &5' -------------GCCCTGTG- 3' SPSB2 hsa-miR-513a-5p beg:0 end:10 pic:3' TACTGTGGAGGGACACTT 5'& |||||||| &5' ---------CCCTGTGA- 3' SPSB2 hsa-miR-24 beg:93 end:112 pic:3' GACAAGGACGACT-TGACTCGGT 5'& ||| ||| .||||||| &5' ------CTGGTGAGGCTGAGCC- 3' SPSB2 hsa-miR-4283 beg:101 end:114 pic:3' TTTGAGCGACTCGGGGT 5'& |||||||||| &5' ------GCTGAGCCCC- 3' SPSB2 hsa-miR-19b-1star beg:198 end:217 pic:3' CGACCTACGTTTGGA-CGTTTTGA 5'& |. .|. ||||||| &5' -------GTCTGCTACGCAAAAC- 3' SPSB2 hsa-miR-19b-2star beg:198 end:217 pic:3' ACTTTACGTTTGGA-CGTTTTGA 5'& |. .|. ||||||| &5' ------GTCTGCTACGCAAAAC- 3' SPSB2 hsa-miR-1226 beg:92 end:103 pic:3' GATCCCTTGTGTCCCGACCACT 5'& |||||||| &5' --------------GCTGGTGA 3' SPSB2 hcmv-miR-UL22Astar beg:81 end:103 pic:3' GATGTTTGATCGTAA---GACCACT 5'& |.|| || ||||||| &5' -----AGCT-GCTGAAAGCTGGTGA 3' SPSB2 hcmv-miR-UL70-5p beg:93 end:111 pic:3' AGACCTGCTCCGGCTCTGCGT 5'& |||| .|||||.||| | &5' -CTGG-TGAGGCTGAG-C--- 3' SPSB2 hcmv-miR-US25-2-5p beg:0 end:23 pic:3' AGTAGGTGGACT----TGTCTGGCGA 5'& || . ||| ||||||.|. &5' ----CCCTGTGATACCACAGACTGT- 3' SPSB2 hsa-let-7a-2star beg:88 end:111 pic:3' CCTTTCGATC-CTCCGACATGTC 5'& |||||||.| ||||||| .| &5' -GAAAGCTGGTGAGGCTGAGC-- 3' SPSB2 hsa-miR-103-2star beg:158 end:181 pic:3' GTTCCGTCGTGACATTTCTTCGA 5'& .||| || | ||.|.||| &5' -GAGGGAGGAAGA-AAGGGAGC- 3' SPSB2 hsa-miR-1227 beg:48 end:70 pic:3' GACCCCTTT-TCCCACCGTGC 5'& ||||||.. .||| ||||| &5' -TGGGGAGGTGGGGAGGCAC- 3' SPSB2 hsa-miR-1229 beg:88 end:105 pic:3' GACACCCTCCCGTCACCACTCTC 5'& || || |||||||. &5' ------GAAAGC--TGGTGAGG- 3' SPSB2 hsa-miR-1234 beg:94 end:109 pic:3' CACCCCACCCACCAGTCCGGCT 5'& |||| ||||.|| &5' ----------TGGTGAGGCTGA 3' SPSB2 hsa-miR-125b-1star beg:141 end:161 pic:3' TCGAGGGTTCTCGGATTGGGCA 5'& ||| ||| |||||| ||..| &5' AGC-CCC-AGAGCC--ACTTG- 3' SPSB2 hsa-miR-1260 beg:48 end:64 pic:3' ACCACCGTCTCCACCCTA 5'& ||| .||||||||. &5' ---TGG-GGAGGTGGGG- 3' SPSB2 hsa-miR-1260b beg:48 end:64 pic:3' TACCACCGTCACCACCCTA 5'& ||| || ||||||. &5' -TGG-GGA---GGTGGGG- 3' SPSB2 hsa-miR-1281 beg:50 end:68 pic:3' CCCTCTCCTCCTCCGCT 5'& |||||. |.|||||| &5' GGGAGGTGGGGAGGC-- 3' SPSB2 hsa-miR-1282 beg:162 end:186 pic:3' TTCG-TCTTTTTC-CGTTTGCT 5'& .|| |||||..| || .|| &5' GAGGAAGAAAGGGAGCCGGCG- 3' SPSB2 hsa-miR-1306 beg:142 end:161 pic:3' GTGGTGGTCTCGGTT-GCA 5'& .|| ||||||||| .| &5' -GCC-CCAGAGCCACTTG- 3' SPSB2 hsa-miR-1308 beg:145 end:160 pic:3' GGTGACTTGGTGGGTACG 5'& ||| ||.||||.. &5' CCA--GAGCCACTT---- 3' SPSB2 hsa-miR-130bstar beg:158 end:178 pic:3' CATCACGTTGTCC--CTTTCTCA 5'& | . ||| |||||.| &5' -----GAGGGAGGAAGAAAGGG- 3' SPSB2 hsa-miR-130bstar beg:150 end:168 pic:3' CATCACGTTGTCCCTTTCTCA 5'& || || |||..||| &5' -----GCCACTTGGAGGGAG- 3' SPSB2 hsa-miR-151-3p beg:183 end:206 pic:3' GGAGTTCCTCGAA-GTCAGATC 5'& .|||||| ||||||. &5' -TTCAAGGCTATGACAGTCTG- 3' SPSB2 hsa-miR-154 beg:59 end:80 pic:3' GCTTCCGTTGTGCCTATTGGAT 5'& |.||||| .| |..|||| &5' -GGAGGCACTGC---TGGCCTA 3' SPSB2 hsa-miR-1825 beg:51 end:71 pic:3' CCTCT-CCTC-CCGTGACCT 5'& ||||. ||.| ||||||| &5' GGAGGTGGGGAGGCACTG-- 3' SPSB2 hsa-miR-1910 beg:53 end:76 pic:3' TCCG-CCGTCCGTGTCCTGACC 5'& |||. || |||||| .|||| &5' AGGTGGGGAGGCACT--GCTGG 3' SPSB2 hsa-miR-194 beg:237 end:253 pic:3' AGGTGTACCTCAACGACAATGT 5'& ||| ||.|||||.| &5' --------GAGATGTTGTTATA 3' SPSB2 hsa-miR-19astar beg:197 end:217 pic:3' ACATCACGTTGATACGTTTTGA 5'& ||| | .||| ||||||| &5' ---AGT-CTGCTACGCAAAAC- 3' SPSB2 hsa-miR-200cstar beg:92 end:106 pic:3' GGTTTGTGACGACCCATTCTGC 5'& ||| |||.||.| &5' ---------GCT-GGTGAGGC- 3' SPSB2 hsa-miR-204 beg:157 end:180 pic:3' TCCGTATCCTACTG-TTTCCCTT 5'& || .||| || |||||||. &5' -GGA--GGGAGGAAGAAAGGGAG 3' SPSB2 hsa-miR-2052 beg:195 end:217 pic:3' TGTAATGACAATA-GTTTTGT 5'& ||| ||| ||||||| &5' ACAGT-CTGCTACGCAAAACA 3' SPSB2 hsa-miR-211 beg:158 end:180 pic:3' TCCGCTTCCTACTG-TTTCCCTT 5'& ||.||| || |||||||. &5' ----GAGGGAGGAAGAAAGGGAG 3' SPSB2 hsa-miR-23astar beg:133 end:156 pic:3' TTTAGG-GTAGGGGTCCTTGGGG 5'& ||||| || ||||| ||.|| &5' AAATCAACAGCCCCA-GAGCC-- 3' SPSB2 hsa-miR-27a beg:0 end:10 pic:3' CGCCTTGAATCGGTGACACTT 5'& ||| |||||| &5' ----------GCC-CTGTGA- 3' SPSB2 hsa-miR-27astar beg:92 end:113 pic:3' ACGAGTGTTCGTCGATTCGGGA 5'& ||| . || |||.||||| &5' -GCTGGTGAG--GCTGAGCCC- 3' SPSB2 hsa-miR-27b beg:0 end:10 pic:3' CGTCTTGAATCGGTGACACTT 5'& ||| |||||| &5' ----------GCC-CTGTGA- 3' SPSB2 hsa-miR-3065-3p beg:9 end:28 pic:3' GAGGTTGTTATAGGACCACGACT 5'& || |||. || ||||||| &5' --CC-ACAGA---CT-GTGCTGA 3' SPSB2 hsa-miR-31 beg:16 end:37 pic:3' TCGATACGGTCGTAGAACGGA 5'& ||.|||.. .||||||| &5' --CTGTGCTGAGGTCTTGCC- 3' SPSB2 hsa-miR-3183 beg:47 end:68 pic:3' AGGCTCGCTGAGGCTCTCTCCG 5'& || | |. .|.||||| &5' -CCTTGGGGAGGT-GGGGAGGC 3' SPSB2 hsa-miR-330-5p beg:131 end:154 pic:3' CGGATTCTG----TGTCCGGGTCTCT 5'& .|| |||| ||||||| &5' -----GGAAATCAACAGCCCCAGAG- 3' SPSB2 hsa-miR-338-5p beg:231 end:251 pic:3' GTGAGTCGTGGTC-CTATAACAA 5'& .||.| || |||.||||| &5' ----TAGTA--AGAGATGTTGTT 3' SPSB2 hsa-miR-33bstar beg:50 end:71 pic:3' CCCGACGTGACGGCTCCGTGAC 5'& ||| . || ||||||||| &5' GGGA---GGTGGGGAGGCACTG 3' SPSB2 hsa-miR-4257 beg:102 end:120 pic:3' GAGTCAGGGGTGGAGACC 5'& || || |||.||| | &5' CTGAGCCCCTACCCC--- 3' SPSB2 hsa-miR-4260 beg:131 end:152 pic:3' AC-CCTGAGGTA--CGGGGTTC 5'& | ||| .|| ||||||. &5' -GCGGAAATCAACAGCCCCAG- 3' SPSB2 hsa-miR-4263 beg:142 end:164 pic:3' CCGG---TTCCGTGAATCTTA 5'& ||| .|| |||||.||. &5' -GCCCCAGAGCCACTTGGAG- 3' SPSB2 hsa-miR-4264 beg:95 end:110 pic:3' TTACTGGTACTGACTCA 5'& ..||| |.||||| &5' GGTGA----GGCTGAG- 3' SPSB2 hsa-miR-4274 beg:54 end:75 pic:3' GTC-CCCCTCCCTGACGAC 5'& .| ||||||| ||||||| &5' -GGTGGGGAGGCACTGCTG 3' SPSB2 hsa-miR-4283 beg:141 end:151 pic:3' TTTGAGCGACTCGGGGT 5'& ||||||| &5' ----------AGCCCCA 3' SPSB2 hsa-miR-4290 beg:158 end:178 pic:3' CTCCCTTCTTTCCTCCCGT 5'& ||||||.|||. |||| &5' GAGGGAGGAAGAAAGGG-- 3' SPSB2 hsa-miR-4296 beg:97 end:113 pic:3' ACTCGGACTCGGGTGTA 5'& |||| |||||||| &5' TGAGGCTGAGCCC---- 3' SPSB2 hsa-miR-4323 beg:86 end:108 pic:3' AGACTC-CGA-CACCCCGAC 5'& |||| ||| ||| ||||| &5' -CTGAAAGCTGGTGAGGCTG 3' SPSB2 hsa-miR-432star beg:51 end:71 pic:3' TCTGTACCTCCTCGGTAGGTC 5'& .|| .||| |||| || |. &5' GGAGGTGG-GGAGGCA-CT-- 3' SPSB2 hsa-miR-516a-3p beg:55 end:69 pic:3' TGGGAGACTTTCCTTCGT 5'& | .|||.||| &5' -------GTGGGGAGGCA 3' SPSB2 hsa-miR-516bstar beg:55 end:69 pic:3' TGGGAGACTTTCCTTCGT 5'& | .|||.||| &5' -------GTGGGGAGGCA 3' SPSB2 hsa-miR-601 beg:66 end:84 pic:3' GAGGAGGTTGTTAGGATCTGGT 5'& | .| ||||||||| &5' ------CTGCTGGCCTAGACCA 3' SPSB2 hsa-miR-608 beg:23 end:45 pic:3' TGCCTCGACAGGGTTGTGGTGGGGA 5'& ||| |||.. |||||||||| &5' ---GAG--GTCTTGCCACCACCCCT 3' SPSB2 hsa-miR-621 beg:57 end:78 pic:3' TCCATTCGCGACAACGATCGG 5'& || || || ||||.||| &5' -GGGGAG-GCAC-TGCTGGCC 3' SPSB2 hsa-miR-653 beg:231 end:253 pic:3' GTCA-TCTCTAACAAAGTTGTG 5'& .||| ||||| |||| |.| &5' TAGTAAGAGA-TGTTGTTATA- 3' SPSB2 hsa-miR-657 beg:93 end:118 pic:3' GGATCTCTCCCACTCTTGGACGG 5'& ||.| |||| |||| ||| || &5' -CTGGTGAGGCTGAGCCCCTACC 3' SPSB2 hsa-miR-760 beg:136 end:156 pic:3' AGGGGTGTCTGGGTCTCGGC 5'& .| |||| ||||||||| &5' --TCAACAGCCCCAGAGCC- 3' SPSB2 hsa-miR-876-3p beg:19 end:41 pic:3' ACTTAATGAAA-CATT-TGGTGGT 5'& |.|| || .|||||| &5' -----TGCTGAGGTCTTGCCACCA 3' SPSB2 hsa-miR-890 beg:215 end:230 pic:3' GTTGACTACGGAAAGGTTCAT 5'& ..|||.|||||| &5' ---------TTTTTTCAAGTA 3'

DNA & RNA Element - SomamiR Gene Name Mutation Mutation ID miR ID Chromosome Location Ref Alt mirsite mirseed Seed Class Sample Name Cancer Type SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-101-3p chr12 6871125 C T ggggagGTACTGctg UACAGUAC m6c PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-1271-3p chr12 6871125 C T ggggAGGCACTgctg AGUGCCUG m7a PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-1281 chr12 6871125 C T ggGGAGGCactgctg UCGCCUCC m6c PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-130a-3p chr12 6871125 C T ggggagGCACTGctg CAGUGCAA m6a PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-130b-3p chr12 6871125 C T ggggagGCACTGctg CAGUGCAA m6a PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-148a-3p chr12 6871125 C T ggggagGCACTGctg UCAGUGCA m6b PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-148b-3p chr12 6871125 C T ggggagGCACTGctg UCAGUGCA m6b PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-152-3p chr12 6871125 C T ggggagGCACTGctg UCAGUGCA m6b PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-1825 chr12 6871125 C T ggggagGCACTGctg UCCAGUGC m6c PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-1909-5p chr12 6871125 C T ggggaGGCACTgctg UGAGUGCC m6c PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-1911-5p chr12 6871125 C T ggggaGGTACTgctg UGAGUACC m6c PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-301a-3p chr12 6871125 C T ggggagGCACTGctg CAGUGCAA m6a PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-301b-3p chr12 6871125 C T ggggagGCACTGctg CAGUGCAA m6a PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-3129-5p chr12 6871125 C T ggggaggTACTGCtg GCAGUAGU m6a PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-3152-5p chr12 6871125 C T gggGAGGCActgctg AUUGCCUC m6c PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-33b-3p chr12 6871125 C T ggggAGGCACTGctg CAGUGCCU m8a PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-34a-5p chr12 6871125 C T ggggaggCACTGCtg UGGCAGUG m6c PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-34c-5p chr12 6871125 C T ggggaggCACTGCtg AGGCAGUG m6c PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-3666 chr12 6871125 C T ggggagGCACTGctg CAGUGCAA m6a PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-371a-3p chr12 6871125 C T ggggaGGCACTgctg AAGUGCCG m6b PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-371b-3p chr12 6871125 C T ggggaGGCACTgctg AAGUGCCC m6b PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-4295 chr12 6871125 C T ggggagGCACTGctg CAGUGCAA m6a PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-449a chr12 6871125 C T ggggaggCACTGCtg UGGCAGUG m6c PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-449b-5p chr12 6871125 C T ggggaggCACTGCtg AGGCAGUG m6c PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-4519 chr12 6871125 C T ggggaggCACTGCTg CAGCAGUG m7b PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-4712-5p chr12 6871125 C T ggggagGTACTGctg UCCAGUAC m6c PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-4724-3p chr12 6871125 C T ggggAGGTACtgctg GUACCUUC m6a PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-4777-3p chr12 6871125 C T gggGAGGTActgctg AUACCUCA m6b PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-515-3p chr12 6871125 C T ggggAGGCACTgctg GAGUGCCU m7b PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-519e-3p chr12 6871125 C T ggggAGGCACTgctg AAGUGCCU m7b PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-550a-3-5p chr12 6871125 C T ggggAGGCACTgctg AGUGCCUG m7a PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-550a-5p chr12 6871125 C T ggggAGGCACTgctg AGUGCCUG m7a PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-550b-2-5p chr12 6871125 C T ggggAGGCACtgctg AUGUGCCU m6c PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-5693 chr12 6871125 C T ggggaggCACTGCtg GCAGUGGC m6a PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-624-5p chr12 6871125 C T ggggaGGTACTgctg UAGUACCA m6b PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-6499-3p chr12 6871125 C T ggggaggCACTGCTg AGCAGUGU m7a PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-660-3p chr12 6871125 C T ggGGAGGTactgctg ACCUCCUG m6a PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-6778-3p chr12 6871125 C T gGGGAGGCActgctg UGCCUCCC m8a PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-6781-3p chr12 6871125 C T gggGAGGCActgctg UGCCUCUU m6a PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-6791-3p chr12 6871125 C T ggGGAGGCActgctg UGCCUCCU m7a PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-6829-3p chr12 6871125 C T ggGGAGGCActgctg UGCCUCCU m7a PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-6836-3p chr12 6871125 C T ggGGAGGCActgctg AUGCCUCC m7b PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-770-5p chr12 6871125 C T ggggagGTACTGctg UCCAGUAC m6c PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN4892226 hsa-miR-875-5p chr12 6871125 C T gggGAGGTActgctg UAUACCUC m6c PCSI_0090_Pa_P [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-101-3p chr12 6871125 C T ggggagGTACTGctg UACAGUAC m6c PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-1271-3p chr12 6871125 C T ggggAGGCACTgctg AGUGCCUG m7a PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-1281 chr12 6871125 C T ggGGAGGCactgctg UCGCCUCC m6c PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-130a-3p chr12 6871125 C T ggggagGCACTGctg CAGUGCAA m6a PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-130b-3p chr12 6871125 C T ggggagGCACTGctg CAGUGCAA m6a PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-148a-3p chr12 6871125 C T ggggagGCACTGctg UCAGUGCA m6b PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-148b-3p chr12 6871125 C T ggggagGCACTGctg UCAGUGCA m6b PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-152-3p chr12 6871125 C T ggggagGCACTGctg UCAGUGCA m6b PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-1825 chr12 6871125 C T ggggagGCACTGctg UCCAGUGC m6c PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-1909-5p chr12 6871125 C T ggggaGGCACTgctg UGAGUGCC m6c PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-1911-5p chr12 6871125 C T ggggaGGTACTgctg UGAGUACC m6c PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-301a-3p chr12 6871125 C T ggggagGCACTGctg CAGUGCAA m6a PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-301b-3p chr12 6871125 C T ggggagGCACTGctg CAGUGCAA m6a PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-3129-5p chr12 6871125 C T ggggaggTACTGCtg GCAGUAGU m6a PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-3152-5p chr12 6871125 C T gggGAGGCActgctg AUUGCCUC m6c PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-33b-3p chr12 6871125 C T ggggAGGCACTGctg CAGUGCCU m8a PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-34a-5p chr12 6871125 C T ggggaggCACTGCtg UGGCAGUG m6c PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-34c-5p chr12 6871125 C T ggggaggCACTGCtg AGGCAGUG m6c PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-3666 chr12 6871125 C T ggggagGCACTGctg CAGUGCAA m6a PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-371a-3p chr12 6871125 C T ggggaGGCACTgctg AAGUGCCG m6b PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-371b-3p chr12 6871125 C T ggggaGGCACTgctg AAGUGCCC m6b PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-4295 chr12 6871125 C T ggggagGCACTGctg CAGUGCAA m6a PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-449a chr12 6871125 C T ggggaggCACTGCtg UGGCAGUG m6c PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-449b-5p chr12 6871125 C T ggggaggCACTGCtg AGGCAGUG m6c PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-4519 chr12 6871125 C T ggggaggCACTGCTg CAGCAGUG m7b PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-4712-5p chr12 6871125 C T ggggagGTACTGctg UCCAGUAC m6c PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-4724-3p chr12 6871125 C T ggggAGGTACtgctg GUACCUUC m6a PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-4777-3p chr12 6871125 C T gggGAGGTActgctg AUACCUCA m6b PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-515-3p chr12 6871125 C T ggggAGGCACTgctg GAGUGCCU m7b PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-519e-3p chr12 6871125 C T ggggAGGCACTgctg AAGUGCCU m7b PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-550a-3-5p chr12 6871125 C T ggggAGGCACTgctg AGUGCCUG m7a PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-550a-5p chr12 6871125 C T ggggAGGCACTgctg AGUGCCUG m7a PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-550b-2-5p chr12 6871125 C T ggggAGGCACtgctg AUGUGCCU m6c PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-5693 chr12 6871125 C T ggggaggCACTGCtg GCAGUGGC m6a PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-624-5p chr12 6871125 C T ggggaGGTACTgctg UAGUACCA m6b PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-6499-3p chr12 6871125 C T ggggaggCACTGCTg AGCAGUGU m7a PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-660-3p chr12 6871125 C T ggGGAGGTactgctg ACCUCCUG m6a PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-6778-3p chr12 6871125 C T gGGGAGGCActgctg UGCCUCCC m8a PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-6781-3p chr12 6871125 C T gggGAGGCActgctg UGCCUCUU m6a PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-6791-3p chr12 6871125 C T ggGGAGGCActgctg UGCCUCCU m7a PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-6829-3p chr12 6871125 C T ggGGAGGCActgctg UGCCUCCU m7a PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-6836-3p chr12 6871125 C T ggGGAGGCActgctg AUGCCUCC m7b PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-770-5p chr12 6871125 C T ggggagGTACTGctg UCCAGUAC m6c PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS] SPSB2 chr12:g.6871125C>T COSN14654122 hsa-miR-875-5p chr12 6871125 C T gggGAGGTActgctg UAUACCUC m6c PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS]

DNA & RNA Element - miRcode Gene Name Type microRNA Seed Position Seed Type Total Cons% Tr Region SPSB2 High_conserved miR-503 chr12:6981694 7-mer-m8 40 CDS SPSB2 High_conserved miR-132/212/212-3p chr12:6981905 7-mer-m8 13 CDS SPSB2 High_conserved miR-7/7ab chr12:6998482 7-mer-A1 9 ncRNA SPSB2 High_conserved miR-133abc chr12:6986671 7-mer-A1 7 5pUTR, ncRNA SPSB2 High_conserved miR-9/9ab chr12:6981911 7-mer-A1 11 CDS SPSB2 High_conserved miR-137/137ab chr12:6981220 7-mer-m8 20 3pUTR SPSB2 High_conserved miR-139-5p chr12:6980804 7-mer-A1 9 3pUTR SPSB2 High_conserved miR-140/140-5p/876-3p/1244 chr12:6981707 7-mer-A1 42 CDS SPSB2 High_conserved miR-143/1721/4770 chr12:6991379 7-mer-A1 9 5pUTR, ncRNA SPSB2 High_conserved miR-145 chr12:6982134 7-mer-m8 16 5pUTR SPSB2 High_conserved miR-146ac/146b-5p chr12:6981179 7-mer-m8 13 3pUTR SPSB2 High_conserved miR-148ab-3p/152 chr12:6981839 7-mer-A1 31 CDS SPSB2 High_conserved miR-150/5127 chr12:6981789 7-mer-A1 60 CDS SPSB2 High_conserved miR-192/215 chr12:6981887 7-mer-A1 31 CDS SPSB2 High_conserved miR-192/215 chr12:6982146 7-mer-A1 11 5pUTR SPSB2 High_conserved miR-193/193b/193a-3p chr12:6981170 8-mer 11 3pUTR SPSB2 High_conserved miR-193/193b/193a-3p chr12:6981437 7-mer-m8 40 CDS SPSB2 High_conserved miR-199ab-5p chr12:6980935 7-mer-m8 9 3pUTR SPSB2 High_conserved miR-204/204b/211 chr12:6980177 7-mer-m8 7 3pUTR SPSB2 High_conserved miR-214/761/3619-5p chr12:6980264 7-mer-A1 9 3pUTR SPSB2 High_conserved miR-221/222/222ab/1928 chr12:6984955 7-mer-A1 9 ncRNA SPSB2 High_conserved miR-223 chr12:6980850 7-mer-m8 20 3pUTR SPSB2 High_conserved miR-122/122a/1352 chr12:6980469 7-mer-m8 42 CDS SPSB2 High_conserved miR-24/24ab/24-3p chr12:6980244 7-mer-m8 7 3pUTR SPSB2 High_conserved miR-24/24ab/24-3p chr12:6980453 7-mer-m8 42 CDS SPSB2 High_conserved miR-31 chr12:6980319 8-mer 18 3pUTR SPSB2 High_conserved miR-125a-5p/125b-5p/351/670/4319 chr12:6981592 7-mer-m8 31 CDS SPSB2 High_conserved miR-129-5p/129ab-5p chr12:6998515 7-mer-A1 7 ncRNA SPSB2 Medium_conserved miR-539/539-5p chr12:6981187 7-mer-A1 11 3pUTR SPSB2 Medium_conserved miR-590-3p chr12:6998504 7-mer-A1 2 ncRNA SPSB2 Medium_conserved miR-615-3p chr12:6980413 7-mer-m8 9 CDS SPSB2 Medium_conserved miR-136 chr12:6980942 7-mer-A1 9 3pUTR SPSB2 Medium_conserved miR-136 chr12:6981146 7-mer-m8 24 3pUTR SPSB2 Medium_conserved miR-149 chr12:6981032 7-mer-m8 11 3pUTR SPSB2 Medium_conserved miR-197 chr12:6981161 7-mer-A1 29 3pUTR SPSB2 Medium_conserved miR-197 chr12:6998496 7-mer-A1 7 ncRNA SPSB2 Medium_conserved miR-224 chr12:6985002 7-mer-m8 11 ncRNA SPSB2 Medium_conserved miR-28-5p/708/1407/1653/3139 chr12:6982072 7-mer-m8 16 5pUTR SPSB2 Medium_conserved miR-299/299-3p/3563-3p chr12:6980978 7-mer-A1 16 3pUTR SPSB2 Medium_conserved miR-299/299-3p/3563-3p chr12:6986711 7-mer-m8 7 5pUTR, ncRNA SPSB2 Medium_conserved miR-326/330/330-5p chr12:6980202 7-mer-m8 22 3pUTR SPSB2 Medium_conserved miR-326/330/330-5p chr12:6981570 7-mer-A1 31 CDS SPSB2 Medium_conserved miR-326/330/330-5p chr12:6981844 7-mer-m8 47 CDS SPSB2 Medium_conserved miR-328a/328b-3p chr12:6980792 7-mer-m8 13 3pUTR SPSB2 Medium_conserved miR-346 chr12:6981383 7-mer-m8 7 CDS SPSB2 Medium_conserved miR-370 chr12:6980874 7-mer-m8 7 3pUTR SPSB2 Medium_conserved miR-378/422a/378bcdefhi chr12:6986749 7-mer-m8 13 5pUTR, ncRNA SPSB2 Medium_conserved miR-379/1193-5p/3529 chr12:6980360 7-mer-A1 62 CDS SPSB2 Medium_conserved miR-411 chr12:6984992 7-mer-m8 11 ncRNA SPSB2 Medium_conserved miR-125a-3p/1554 chr12:6980457 7-mer-A1 49 CDS SPSB2 Medium_conserved miR-450a/451a chr12:6980141 7-mer-A1 11 3pUTR SPSB2 Medium_conserved miR-486-5p/3107 chr12:6981058 7-mer-m8 9 3pUTR SPSB2 Medium_conserved miR-491-5p chr12:6986713 8-mer 13 5pUTR, ncRNA

DNA & RNA Element - RAID2 Gene Name RAID ID Interactor 1 Category 1 ID 1 Interactor 2 Category 2 ID 2 Methods Score SPSB2 RAID00003478 hsa-miR-346 miRNA MIMAT0000773 SPSB2 mRNA 84727 CLIP-seq//Prediction 0.6308 SPSB2 RAID00635047 hsa-miR-185-3p miRNA MIMAT0004611 SPSB2 mRNA 84727 Prediction 0.1828 SPSB2 RAID01524330 hsa-miR-4291 miRNA MIMAT0016922 SPSB2 mRNA 84727 Prediction 0.1828 SPSB2 RAID01811003 hsa-miR-4283 miRNA MIMAT0016914 SPSB2 mRNA 84727 Prediction 0.1828 SPSB2 RAID02048423 hsa-miR-410-3p miRNA MIMAT0002171 SPSB2 mRNA 84727 Prediction 0.1828 SPSB2 RAID03087873 hsa-miR-31-5p miRNA MIMAT0000089 SPSB2 mRNA 84727 CLIP-seq//Prediction 0.6308 SPSB2 RAID04494300 TUG1 lncRNA 55000 SPSB2 protein 84727 Microarray//RNA-seq 0.6606