PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus MAGEA8 UBE3A 24722188 biogrid exp P G G P G P P P P P P GP P G P P GP G UBE3A NELFCD 21988832,17131388 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE3A IPO11 22863883 biogrid exp G UBE3A SACS 23671107 biogrid exp G GP G G GP GP G GP GP G P P GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G PLAUR UBE3A 26186194 biogrid exp G G G G GP GP G G GP G GP G G G G G GP G GP G G G G G G G G GP G SUMO3 UBE3A 21900206 biogrid,mint,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ARNTL UBE3A 24728990,25660546 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G AR UBE3A 16254014,9891052 hprd,biogrid,dip exp GP G G G G G G G G G G G G G G G G G G G G G G G GP G UBE3A PARVA 21900206 biogrid,mint,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PTPN3 UBE3A 17166906 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP P GP GP G PDE1B UBE3A 21900206 biogrid,mint,intact exp P P GP P P P P P P P MYH9 UBE3A 16051665 biogrid exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G ARHGEF15 UBE3A 21029865 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A UBE2V1 25260751 intact exp UBE3A ARNTL2 25660546 biogrid exp GP G GP G G G P P GP P GP G G GP GP P UBE3A DDX39B 22939629 biogrid exp P P P P P P P P P P P P P P P P P P P P P P UBC UBE3A 9575161,23439649 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ARPC1B UBE3A 22863883 biogrid exp G G G G GP GP G G GP G GP G GP GP G G GP G G G GP G G G G GP GP GP G UBE3A UFD1L 22939629 biogrid exp G GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP GP G GP GP G G GP G UBE3A NOMO2 21900206 biogrid,mint,intact exp P P P P P P P P P P P P P P P P P P P P P P ANXA1 UBE3A 19204938 biogrid exp GP G G G GP GP G G GP G GP G GP GP G G GP G G G GP GP GP G G GP G G G PHKA2 UBE3A 16051665 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A EID1 21900206 biogrid,mint,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G APP UBE3A 21832049 biogrid exp G GP G G GP GP G G GP G G G G G G GP GP G GP G GP GP G G GP G G GP G UBE3A AHSP 25416956 biogrid,intact exp G G GP G G G G G G GP G P G G G G G G G P P G G UBA52 UBE3A 21532592 dip exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A PHKG1 16051665 biogrid exp G G G G G GP G G G G GP GP G G GP G G G G GP G G G UBE3A EAPP 16713569 hprd,biogrid,mint,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HSPA8 UBE3A 19233847 biogrid exp P P P P P P P P P P P P P P P P UBE3A LRSAM1 22863883 biogrid exp P GP G P GP G P GP G GP GP P GP P GP GP GP G P GP P P P GP P P G SOD1 UBE3A 23040663 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A FAF2 18775313 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE3A SGK223 21900206 biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G UBE3A TRPV5 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G DR1 UBE3A 22863883 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HBA1, HBA2 UBE3A 21900206 biogrid,mint,intact exp P P P P P P UBE3A UNC45A 22939629 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G NTRK1 UBE3A 25921289 biogrid exp P P P G P P P P P P P P P P P P P P P CALM1, CALM2, CALM3 UBE3A 16051665 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A NDUFA13 21765936 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CEBPZ UBE3A 21900206 biogrid,mint,intact exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G LSM1 UBE3A 22863883 biogrid exp G GP G G GP GP G G GP G G G G G G G GP GP G G G G G G G G G G G UBE3A SF3B3 22939629 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A POLE4 21900206 biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE3A METTL1 22863883 biogrid exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP G G GP GP GP GP G UBE3A LSM5 22939629 biogrid exp GP GP G G GP GP G G GP G GP GP G G G GP GP GP GP G GP G G GP GP G GP GP G UBE3A AFTPH 21900206 biogrid,mint,intact exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP G GP GP G UBE3A PHKB 16051665 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MCM7 UBE3A 9852095 hprd,biogrid,bci exp GP GP G G GP G G G GP G G G G GP G GP G GP G G GP GP GP G GP G GP GP G UBE3A LEPRE1 22863883 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A SRSF9 22939629 biogrid exp P P P P P P P P P P P P P P P P P P P P P UBE3A HPCAL4 21900206 biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G UBE3A ASPM 21633703 biogrid exp P P G GP P P GP P P P P P P P P P P P P P P P GP ANXA2 UBE3A 16051665 biogrid exp GP G G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP GP G G G GP GP GP G UBE3A HIF1AN 22645313 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A UCHL5 24743594,26186194 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMC3 UBE3A 24743594 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A NPLOC4 22863883 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A GOLGA3 16051665 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MYCBP2 UBE3A 16051665 biogrid exp G GP G G G GP G GP GP G G G GP GP G GP GP G GP G G GP G G GP G G GP G TAT UBE3A 25416956,24722188 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G SHFM1 UBE3A 24811749 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE3A YOD1 23827681 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G XRCC6 UBE3A 16051665 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MAGEA1 UBE3A 26186194 biogrid exp P P P GP UBXN1 UBE3A 18775313 biogrid,intact exp GP GP G G G GP G G GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G PSMD3 UBE3A 16051665 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A RMI1 21900206 biogrid,mint,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMC1 UBE3A 26496610 biogrid,intact exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G HSPA4 UBE3A 19233847,23040663 biogrid exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ACTA1 UBE3A 16051665 biogrid exp G G G G G GP G G G G G G G G GP G G G TXNL1 UBE3A 22939629 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CELA2B UBE3A 26186194 biogrid exp G G G G G SCAMP1 UBE3A 16713569 hprd,biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE3A C2orf44 16051665 biogrid exp GP GP G P GP G GP GP G GP GP P P GP GP GP GP G P GP GP GP P GP GP GP G CEBPA UBE3A 23598402 biogrid exp GP G G G GP GP G GP G G GP G GP G G GP GP G GP G GP GP G G GP G GP GP G UBE3A LPP 22863883 biogrid exp GP G G G G GP G GP GP G GP G G G G GP GP GP G G GP G G GP GP G GP G G UBE3A KLHL38 25416956 biogrid,intact exp P P P P P P P P P P P P P P P P P P P P P EIF4G1 UBE3A 21900206 biogrid,mint,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A MAPK6 22645313 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SHBG UBE3A 15862967 hprd,biogrid,i2d,bci exp PHKG2 UBE3A 16051665 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE3A ASAP3 25416956 biogrid,intact exp G G G G G G G G G G G G G GP G G G G G G G G G G G P GP GP G UBE3A ATG9A 25416956 biogrid,intact exp G GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G UBE3A NEURL4 22645313 biogrid exp GP GP G G GP GP G G GP G GP GP GP GP G P GP G P G GP GP GP GP GP GP GP GP G PSMD14 UBE3A 24743594,26496610,17323924 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G G GP GP G GP GP G PSAP UBE3A 21900206 biogrid,mint,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A C11orf49 21900206 biogrid,mint,intact exp G GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G G G GP GP GP GP GP GP G UBE3A SRPRB 26186194 biogrid exp GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP G GP GP GP G GP GP G UBE3A TBC1D14 21900206 biogrid,mint,intact exp GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP G GP GP G MEOX2 UBE3A 24722188 biogrid exp G G G G P GP GP G GP GP G G P SMAD9 UBE3A 15231748 hprd,i2d exp GP GP G P GP G GP GP G GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G UBE3A ARC 23671107 biogrid exp P P G P P P P P P P P P P P P G P P P P P P P UBE3A BTF3L4 22863883 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A TNPO3 22939629 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G UBE3A UBE3A 24273172,15331633,21033666,9688277,9575161,10558980,12620801,22496338 hprd,biogrid,i2d,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HSF1 UBE3A 22863883 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A DKFZp666D103 25416956 intact exp UBB UBE3A 25416956 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A TCF19 21900206 biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE3A TRIM65 21900206 biogrid,mint,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE3A DBNL 22863883 biogrid exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE3A PRDX1 20589759 biogrid exp, ortho GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G USP14 UBE3A 22939629 biogrid exp, ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RAD23B UBE3A 10373495 biogrid exp, ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HERC2 UBE3A 25476789,22645313,21493713 biogrid exp, ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G YWHAE UBE3A 21900206 biogrid,mint,intact exp, ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PML UBE3A 19325566, 25402006 biogrid exp, ortho, pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G BRCA1 UBE3A 12890688, 25402006 biogrid exp, pred P P G GP P P P P P P P GP P P P P P P P P P P GP UBE3A NCOA3 16951183, 25402006 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RARA UBE3A 9891052,16713569, 25402006, 21836163 hprd,biogrid,mint,intact,dip exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G BPY2, BPY2B, BPY2C UBE3A 12207887, 25402006 hprd,biogrid exp, pred UBE2L6 UBE3A 10558980,9153201,17433363, 25402006, 23023127, 21836163 hprd,biogrid,i2d,bci exp, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G TP53 UBE3A 11027293,19364824,9369221,16493710,8090726,7708685,15001357,9450543,9688277,17131388,1661671,12620801,9143503,8380895,23040663, 25402006, 21836163 hprd,biogrid,intact,bci exp, pred G G G G G G G G G G G G G G G GP G G G G GP G G G GP G G GP G UBE2D1 UBE3A 24743594,8090726,15001357,9450543,19240029,9575161,14517261,10066826,8576257, 25402006, 23023127, 21836163, 16082366 hprd,biogrid,bci exp, pred GP G G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP GP G GP G GP GP GP G CFTR UBE3A 19233847,17110338, 21836163 biogrid,intact exp, pred P P GP P P GP P GP P GP GP P YWHAZ UBE3A 21900206, 25402006 biogrid,mint,intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2D2 UBE3A 24743594,19325566,9990509,9182527, 25402006, 23023127, 16082366 biogrid,bci exp, pred GP G G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP GP G GP G GP GP GP G MDM2 UBE3A 11486026, 25402006 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CDKN1B UBE3A 19591933, 25402006 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ESR1 UBE3A 22865929,16314411,9891052, 25402006, 21836163 biogrid,dip exp, pred GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G NR3C1 UBE3A 9891052, 25402006 dip exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G BLK UBE3A 10449731, 25402006 hprd,biogrid,bci exp, pred GP P P P P P P P GP P P P P P GP P P RAD23A UBE3A 23671107,19013454,9153201,10373495, 21836163 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A ESR2 17962381,25408199, 25402006 biogrid exp, pred GP GP G GP GP G GP GP GP GP GP GP G P GP GP GP G GP P GP GP GP GP GP GP UBE3A UBQLN2 10983987, 25402006 hprd,biogrid,bci exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A RNF2 20351251, 25402006 biogrid exp, pred P P P P GP P P P P P P P P P P P UBE2D3 UBE3A 24743594,11486026,9990509, 23023127, 21836163 hprd,biogrid,bci exp, pred GP G G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP GP G GP G GP GP GP G LCK UBE3A 10449731, 25402006, 21836163 biogrid exp, pred G G GP G G G G G G GP G G G G G GP G TSC2 UBE3A 15175323,18298802, 25402006, 21836163 biogrid exp, pred G GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP G G G GP G GP GP G PGR UBE3A 9891052, 25402006 hprd,biogrid,dip exp, pred GP G P G G G G G G G P GP P G P G G G G G G G UBE2L3 UBE3A 22350887,19591933,11027293,19364824,9990509,17433363,20589759,17603074,17131388,9688277,10373495,19899154,11431533,20351251,9575161,16142244,10558980,9153201,8576257,19204938, 25402006, 21836163, 16082366 hprd,biogrid,i2d,intact,dip,bci exp, pred GP G G G G GP G GP GP G GP G G G G GP GP G GP G G G GP GP GP G GP GP G TTC3 UBE3A 21900206, 25402006 biogrid,mint,intact exp, pred P P P P P UBE2G1 UBE3A 10558980, 25402006, 23023127, 21836163, 16082366 hprd,bci exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A JADE1 21900206,24722188,16713569, 21836163 hprd,biogrid,mint,intact exp, pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G UBE2E1 UBE3A 9153201,8576257, 23023127, 16082366 hprd,biogrid,bci exp, pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2G2 UBE3A 10558980, 23023127, 21836163 hprd exp, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP G G GP GP GP GP G UBE3A UBQLN1 10983987, 25402006 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMD4 UBE3A 24743594,22350919,19240029,25633294,22645313, 25402006 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G UBE3A SCRIB 11027293,16482544, 21836163 biogrid,mint,intact exp, pred GP GP G G G G G GP GP G GP GP GP G G GP G G GP G GP GP GP G GP G GP GP G UBE3A BARD1 12890688, 25402006 biogrid exp, pred P G GP P P GP P P P GP G GP P G P P GP P GP P GP GP GP G UBE3A BAK1 9881696, 25402006 mint,intact exp, pred GP GP G G GP G G GP GP G GP GP GP GP G GP G G GP G GP GP GP G GP GP GP GP G UBE3A DLG1 16482544, 21836163 biogrid exp, pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE3A ADRM1 24743594, 25402006 biogrid exp, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PPP5C UBE3A ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A ECT2 ortho G G G G G G G G G G UBE2C UBE3A 23023127, 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A RNF111 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A SFTPA2 21836163 pred GP G G SRC UBE3A 25402006 pred GP GP G GP GP G G GP G G G G GP GP G G G GP GP G GP GP GP GP G UBE3A RNF125 25402006 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP P G UBE3A RBM39 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE3A UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE3A HUWE1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G BCL2 UBE3A 25402006 pred G G G G GP GP G G GP G GP G G GP G G GP GP G G GP GP G G G GP G G G NRIP1 UBE3A 25402006 pred GP GP G G GP GP G GP GP G GP GP G GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CNOT4 UBE3A 25402006, 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A SIAH1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A MCL1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CDK1 UBE3A 25402006 pred GP G GP G GP P P P GP GP GP G GP P GP GP GP GP UBE3A MED1 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A RNF25 25402006 pred P G P P P P P P P P P P P P P GP P P BID UBE3A 25402006 pred G G G GP G G GP GP G G GP GP GP G GP G G GP G G GP G GP GP GP GP UBOX5 UBE3A 25402006 pred GP GP G G G GP G GP P G G G GP GP G P GP G G G G G GP P GP GP GP G G ARIH2 UBE3A 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MNAT1 UBE3A 25402006 pred GP GP G P GP G G GP G GP GP GP G GP GP G P G P GP GP G GP G GP P PARP1 UBE3A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G NR4A1 UBE3A 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SFN UBE3A 25402006 pred GP G G G G G G G G G G G GP G G G G GP G G G GP G G G G G G G UBE3A UBE2D4 23023127 pred GP G G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP GP G GP G GP GP GP G UBE3A UBE2U 23023127 pred P P P P P P P P P P P P P P P P P P P P GP UBR5 UBE3A 23023127 pred GP G G G G GP G G GP G GP GP GP GP G G GP G G G GP G G G G G GP GP G UBE3A BTRC 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G UBE3A MTA1 25402006 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP G GP G GP G GP GP G TAF6 UBE3A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMC5 UBE3A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A CCNB1IP1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE3A NFX1 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE3A STUB1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G BMP7 UBE3A 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G UBE3A COPS5 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2H UBE3A 25402006, 23023127, 16082366 pred GP GP G G GP GP G GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A HERC5 23023127 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G GP G G GP GP G GP GP G NEDD4 UBE3A 25402006, 23023127 pred GP GP G GP P G GP GP GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP P G PIAS1 UBE3A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A BIRC3 25402006 pred GP G GP G G GP P GP G GP G GP G GP P G GP GP GP GP GP UBE3A RNF11 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ALDH1A3 UBE3A 21836163 pred GP G G GP GP G G GP G GP P GP G G GP GP G GP G GP GP GP G GP G GP GP G UBE3A ITCH 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A CREBBP 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CDKN1A UBE3A 25402006 pred GP GP G G GP G G G GP G G G GP G G GP G G G G GP G G G GP G G GP G UBE3A RNF5 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G UBE3A CDK5R1 16082366 pred G G G G G G G G G UBE3A RBBP4 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A AKTIP 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A HERC3 25402006 pred GP GP G G G GP G GP GP G GP GP P GP G GP GP P G P GP GP GP P GP GP P G SP1 UBE3A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G STAT1 UBE3A 25402006 pred G G G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP G G GP GP G GP G UBE3A EZH2 25402006 pred GP P G GP GP P GP G GP G P P P GP GP GP GP UBE3A MED17 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2N UBE3A 25402006, 23023127, 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G YWHAG UBE3A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CDC34 UBE3A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2I UBE3A 23023127, 16082366 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE3A UBE2E2 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G DAPK1 UBE3A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A MRAP 21836163 pred GP GP G G GP GP G GP GP G P GP GP GP G GP GP G GP G GP GP GP GP GP P GP GP GSK3B UBE3A 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G G G G UBE3A TRIM5 25402006, 21836163 pred GP GP G GP P G GP GP GP GP GP GP G GP P GP GP G GP GP GP P GP GP GP P G TP73 UBE3A 25402006 pred G G G G G XIAP UBE3A 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP G GP G GP GP G UBE3A RCHY1 25402006 pred G GP G G G GP G GP GP G GP G GP G G GP GP G GP G G G GP G GP G GP G G UBE3A NCOA2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NFKBIA UBE3A 25402006 pred G GP G G GP GP G GP GP G G G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G UBE3A TRAF6 25402006 pred GP GP G G GP G G GP GP G GP GP GP G G GP G GP G G GP GP GP G GP GP GP GP G UBE3A SMAD4 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP G GP GP GP GP G UBE3A RBBP7 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2A UBE3A 23023127, 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TADA3 UBE3A 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G UBE3A RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G EPS15 UBE3A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HSP90AA1 UBE3A 25402006 pred GP GP G G G GP G G GP G G G G G G G GP G G G GP G G G G G G GP G UBE3A JDP2 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ZIC2 UBE3A 16082366 pred G G G G G UBE3A PTK2 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RNF144A UBE3A 25402006 pred G GP G G GP GP G GP GP G GP P GP GP G GP GP GP GP G P G GP GP GP GP GP P G UBE3A BCL2L1 25402006 pred G GP G G GP GP G G G G GP GP G GP G GP GP G G G G G GP G GP G GP GP G UBE3A DLX2 16082366 pred P GP G G G GP G GP P G P P GP P P GP G GP G P P GP GP P P GP G UBE3A FBXO11 25402006 pred G G G G G GP G G G G G GP GP G G GP GP G G G GP G G G GP G G G G THRB UBE3A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP GP GP GP G CDK7 UBE3A 25402006 pred GP GP G G GP GP G GP GP G GP P GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM24 UBE3A 25402006 pred G G G G G G G G GP G G G GP GP G GP G GP G G GP GP GP GP GP G GP GP G UBE3A SMAD2 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A CTBP1 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A ZNRF1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A RFWD3 25402006 pred G G G G G G G G G G G G G G G G G G UBE3A UBE2NL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NFYB UBE3A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SMARCA4 UBE3A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PARK2 UBE3A 25402006 pred P GP G P GP G GP GP G GP P P G P GP GP P G P GP GP GP P GP G SIPA1L1 UBE3A 21836163 pred P GP G P GP G P P G GP P P P G GP GP P P G P GP GP P GP GP GP GP UBE3A TOPORS 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MECP2 UBE3A 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A PHB2 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A UBE2T 23023127 pred G G G GP G GP P P P GP GP P GP P G GP P GP G UBE3A FOXO1 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G DDX5 UBE3A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A NCOA6 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A RNF19B 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A MAP1S 25402006 pred GP G G G G G G GP GP G GP G GP GP G GP G GP GP G GP GP GP G GP GP GP GP G UBE3A RNF14 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A NCOR2 25402006 pred GP GP G G GP GP G GP GP G GP G GP G G GP GP GP GP G GP GP GP G GP GP GP GP G UBE3A FBXO18 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G GABRB3 UBE3A 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G PLK1 UBE3A 25402006 pred P P G G GP P G GP GP P P P GP GP GP GP GP G GP P GP GP GP P P GP UBE2K UBE3A 23023127, 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G AXIN1 UBE3A 25402006 pred GP GP G GP GP G P GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A KAT5 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A UBE2Q2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE3A EP300 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A UBE2S 23023127 pred G G G G G G G G GP G G G GP G G G G G G G G G G G GP G EZR UBE3A 21836163 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE3A TP63 25402006 pred GP G G G G G G G G G G G G G G G G G G GP GP G G G G G UBE3A BAX 25402006 pred P P G GP P P GP GP P GP P GP P GP P G P GP P P GP GP GP P G XPO1 UBE3A 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MED24 UBE3A 25402006 pred GP G G G G GP G GP GP G G G G G G G GP G GP G G G G G G G G GP G GTF2H1 UBE3A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G FYN UBE3A 25402006 pred G GP G G GP GP G G GP G GP GP G GP G G GP G G G G G G G G GP G G G UBE3A NR0B2 25402006 pred G G G G G G G G G G G G G G G G MAPK1 UBE3A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SAP30 UBE3A 21836163 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G P GP G G GP G GP GP G PIK3CA UBE3A 25402006 pred GP GP G P GP G GP GP G GP GP GP GP G P GP GP GP G P GP GP GP GP GP GP GP ETS1 UBE3A 25402006 pred G G G G GP G G G G G G G G GP G G G G G G G G G G G GP G G G UBE3A ZC3HC1 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MTA2 UBE3A 25402006 pred P P P P P P P P P P GP P P P P P P P P P P P RNF4 UBE3A 25402006 pred GP G G G G GP G GP GP G GP G G G G G GP GP G G GP GP GP GP G G GP GP G UBE3A TRIM25 25402006 pred G GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE3A UBE2F 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G CBL UBE3A 25402006 pred G GP G G GP GP G G GP G GP G GP GP G G GP GP G G G G G G G GP G GP G UBE3A CUEDC2 25402006 pred G G G G GP GP G G G G GP G GP G G GP GP G G G G G G G GP G G G G UBE3A RPS6KA1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G UBE3A NCOA1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CEBPB UBE3A 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A DTX3L 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP G G GP G GP GP GP GP GP GP G ATXN3 UBE3A 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G P GP GP P G GP GP GP GP GP GP GP GP G UBE3A KAT2B 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G NCOR1 UBE3A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G UBE3A USP7 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A ARIH1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A HDAC1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBE3A NFE2L2 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A UHRF1 21836163 pred G G G G G G G G G G G G G G G VDAC2 UBE3A 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP GP GP GP GP G SNRPN UBE3A 21836163 pred G GP G GP UBE3A KLF9 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A DZIP3 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G P GP GP GP GP G GP GP G UBE3A HDAC2 25402006, 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATP10A UBE3A 21836163 pred GP GP G G GP GP G GP GP G GP P GP GP G GP GP G GP G GP GP G P GP P GP GP G PRKDC UBE3A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A UBE2R2 23023127 pred G G G G GP G G G G G G G G GP G G G G G G G G G G G GP GP G G GTF2B UBE3A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A HERPUD1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2B UBE3A 23023127, 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE3A AMFR 25402006, 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE3A RNF144B 25402006 pred G GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP G G G GP G G GP G UBE3A CHFR 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2M UBE3A 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G PIK3R1 UBE3A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants A0A024R1A4 Q05086 - 10558980 - X 2 A0A024R1A4 Q05086 - 9153201 - X 2 A0A024R1A4 Q05086 - 10558980 - X 2 A0A024RDR3 Q05086 - 15231748 - X 2 Q05086 Q05086 - 10558980 - X 2 Q05086 Q05086 - 10558980 - X 2 Q05086 Q05086 - 10558980 - X 2 Q05086 Q05086 - 10558980 - X 2 Q05086 Q05086 - 10558980 - X 2 Q05086 Q05086 - 10558980 - X 2 Q05086 Q05086 - 10558980 - X 2 Q05086 Q05086 - 10558980 - X 2 Q05086 Q05086 - 10558980 - X 2 Q05086 Q05086 - 10558980 - X 2 Q05086 Q05086 - 10558980 - X 2 Q05086 Q05086 - 10558980 - X 2 O14933 Q05086 - 9153201 - X 2 Q05086 affinity chromatography technology 22865929 physical association X 2 Q99728 Q05086 pull down 12890688 direct interaction X 2 Q05086 affinity chromatography technology 16314411 physical association X 2 P61077-3 Q05086 pull down 11486026 direct interaction X 2 P61077-3 Q05086 pull down 24743594 direct interaction X 2 P61077-3 Q05086 enzymatic study 9990509 direct interaction X 2 Q7LC44 Q05086 pull down 23671107 direct interaction X 2 Q05086 affinity chromatography technology 16254014 physical association X 2 O14599 Q05086 affinity chromatography technology 12207887 physical association X 2 O14599 Q05086 two hybrid 12207887 direct interaction X 2 P10276 Q05086 two hybrid 16713569 direct interaction X 2 Q53HF2 Q05086 affinity chromatography technology 19233847 physical association X 2 Q53HF2 Q05086 affinity chromatography technology 19233847 physical association X 2 Q5JPE7-2 Q05086 two hybrid 21900206 direct interaction X 2 A0A087WW00 Q05086 pull down 15001357 direct interaction X 2 A0A087WW00 Q05086 pull down 8090726 direct interaction X 2 A0A087WW00 Q05086 pull down 9575161 direct interaction X 2 A0A087WW00 Q05086 pull down 8576257 direct interaction X 2 A0A087WW00 Q05086 enzymatic study 8576257 direct interaction X 2 A0A087WW00 Q05086 pull down 24743594 direct interaction X 2 A0A087WW00 Q05086 pull down 9450543 direct interaction X 2 A0A087WW00 Q05086 enzymatic study 14517261 direct interaction X 2 A0A087WW00 Q05086 enzymatic study 10066826 direct interaction X 2 Q8IZT6-2 Q05086 two hybrid 21633703 direct interaction X 2 Q8IZT6-2 Q05086 affinity chromatography technology 21633703 physical association X 2 Q8IZT6-2 Q05086 affinity chromatography technology 21633703 physical association X 2 P43361 Q05086 two hybrid 24722188 direct interaction X 2 P17735 Q05086 two hybrid 24722188 direct interaction X 2 P17735 Q05086 two hybrid 25416956 direct interaction X 2 Q96JN8 Q05086 affinity chromatography technology 22645313 physical association X 2 Q96JN8 Q05086 biochemical 22645313 colocalization X 2 C6EMX8 Q05086 pull down 9852095 direct interaction X 2 C6EMX8 Q05086 affinity chromatography technology 9852095 physical association X 2 A0A024R1A4 Q05086 pull down 19899154 direct interaction X 2 A0A024R1A4 Q05086 pull down 17603074 direct interaction X 2 A0A024R1A4 Q05086 fluorescent resonance energy transfer 17433363 direct interaction X 2 A0A024R1A4 Q05086 pull down 17433363 direct interaction X 2 A0A024R1A4 Q05086 pull down 10558980 direct interaction X 2 A0A024R1A4 Q05086 pull down 10373495 direct interaction X 2 A0A024R1A4 Q05086 pull down 19204938 direct interaction X 2 A0A024R1A4 Q05086 pull down 19364824 direct interaction X 2 A0A024R1A4 Q05086 pull down 20351251 direct interaction X 2 A0A024R1A4 Q05086 pull down 9688277 direct interaction X 2 A0A024R1A4 Q05086 pull down 19591933 direct interaction X 2 A0A024R1A4 Q05086 pull down 9575161 direct interaction X 2 A0A024R1A4 Q05086 pull down 20589759 direct interaction X 2 A0A024R1A4 Q05086 pull down 11027293 direct interaction X 2 A0A024R1A4 Q05086 pull down 8576257 direct interaction X 2 A0A024R1A4 Q05086 enzymatic study 8576257 direct interaction X 2 A0A024R1A4 Q05086 pull down 22350887 direct interaction X 2 A0A024R1A4 Q05086 two hybrid 9153201 direct interaction X 2 A0A024R1A4 Q05086 pull down 9153201 direct interaction X 2 A0A024R1A4 Q05086 enzymatic study 9990509 direct interaction X 2 A0A024R1A4 Q05086 x-ray crystallography 10558980 association X 2 A0A024R1A4 Q05086 enzymatic study 10558980 direct interaction X 2 A0A024R1A4 Q05086 affinity chromatography technology 11431533 physical association X 2 A0A024R438 Q05086 two hybrid 25416956 direct interaction X 2 P62258 Q05086 two hybrid 21900206 direct interaction X 2 O95714 Q05086 affinity chromatography technology 22645313 physical association X 2 O95714 Q05086 biochemical 22645313 colocalization X 2 O95714 Q05086 affinity chromatography technology 21493713 physical association X 2 O95714 Q05086 biochemical 21493713 association X 2 Q03701 Q05086 two hybrid 21900206 direct interaction X 2 Q96K17-2 Q05086 biochemical 22863883 colocalization X 2 O94989 Q05086 affinity chromatography technology 21029865 physical association X 2 Q9UM19 Q05086 two hybrid 21900206 direct interaction X 2 P49715 Q05086 affinity chromatography technology 23598402 physical association X 2 P49715 Q05086 pull down 23598402 direct interaction X 2 P49715 Q05086 affinity chromatography technology 23598402 physical association X 2 Q01064-2 Q05086 two hybrid 21900206 direct interaction X 2 Q16659 Q05086 affinity chromatography technology 22645313 physical association X 2 Q16659 Q05086 biochemical 22645313 colocalization X 2 P55036 Q05086 biochemical 22645313 colocalization X 2 P55036 Q05086 enzymatic study 22350919 direct interaction X 2 P55036 Q05086 enzymatic study 24743594 direct interaction X 2 Q05086 pull down 15175323 direct interaction X 2 Q05086 affinity chromatography technology 18298802 physical association X 2 Q05086 pull down 18298802 direct interaction X 2 A4D275 Q05086 biochemical 22863883 colocalization X 2 Q05086 biochemical 22863883 colocalization X 2 P60896 Q05086 affinity chromatography technology 24811749 physical association X 2 P60896 Q05086 affinity chromatography technology 24811749 physical association X 2 B7Z9V1 Q05086 affinity chromatography technology 17166906 physical association X 2 P55854 Q05086 two hybrid 21900206 direct interaction X 2 P54578-3 Q05086 biochemical 22939629 colocalization X 2 Q9UHD9 Q05086 biochemical 10983987 colocalization X 2 Q9UHD9 Q05086 affinity chromatography technology 10983987 physical association X 2 Q9UHD9 Q05086 two hybrid 10983987 direct interaction X 2 Q05086 P04637-7 enzymatic study 8090726 direct interaction X 2 Q05086 P04637-7 pull down 23040663 direct interaction X 2 Q05086 P04637-7 enzymatic study 15001357 direct interaction X 2 Q05086 O15205 affinity chromatography technology 22797925 physical association X 2 Q05086 two hybrid 9891052 direct interaction X 2 Q05086 P04637-7 pull down 16493710 direct interaction X 2 Q05086 P04637-7 affinity chromatography technology 11027293 physical association X 2 Q05086 P04637-7 pull down 11027293 direct interaction X 2 Q05086 Q14160 pull down 11027293 direct interaction X 2 Q05086 P04637-7 enzymatic study 11027293 direct interaction X 2 Q05086 Q14160 enzymatic study 11027293 direct interaction X 2 Q05086 Q14160 pull down 11027293 direct interaction X 2 Q05086 affinity chromatography technology 24728990 physical association X 2 Q05086 affinity chromatography technology 24728990 physical association X 2 Q5VVQ6 Q05086 enzymatic study 23827681 direct interaction X 2 Q05086 P04637-7 pull down 1661671 direct interaction X 2 Q05086 P04637-7 enzymatic study 9450543 direct interaction X 2 Q05086 P04637-7 enzymatic study 7708685 direct interaction X 2 Q05086 pull down 12890688 direct interaction X 2 Q05086 pull down 9891052 direct interaction X 2 Q05086 P04637-7 pull down 9688277 direct interaction X 2 Q05086 P04637-7 pull down 8380895 direct interaction X 2 Q05086 Q12959-4 pull down 16482544 direct interaction X 2 Q05086 Q14160 pull down 16482544 direct interaction X 2 Q05086 P04637-7 affinity chromatography technology 17131388 physical association X 2 Q05086 affinity chromatography technology 16051665 physical association X 2 Q05086 P04637-7 enzymatic study 19364824 direct interaction X 2 Q9NWT6 Q05086 affinity chromatography technology 22645313 physical association X 2 Q9NWT6 Q05086 biochemical 22645313 colocalization X 2 P0CG48 Q05086 affinity chromatography technology 21493713 physical association X 2 P0CG48 Q05086 enzymatic study 9575161 direct interaction X 2 P0CG48 Q05086 affinity chromatography technology 22053931 physical association X 2 P0CG48 Q05086 affinity chromatography technology 22505724 physical association X 2 P0CG48 Q05086 enzymatic study 23439649 direct interaction X 2 P0CG48 Q05086 affinity chromatography technology 23000965 physical association X 2 P0CG48 Q05086 affinity chromatography technology 24816145 physical association X 2 P0CG48 Q05086 affinity chromatography technology 20639865 physical association X 2 P0CG48 Q05086 affinity chromatography technology 22118674 physical association X 2 P0CG48 Q05086 affinity chromatography technology 21987572 physical association X 2 P0CG48 Q05086 affinity chromatography technology 20972266 physical association X 2 P0CG48 Q05086 affinity chromatography technology 21963094 physical association X 2 P0CG48 Q05086 affinity chromatography technology 21139048 physical association X 2 P0CG48 Q05086 affinity chromatography technology 21890473 physical association X 2 P0CG48 Q05086 affinity chromatography technology 21906983 physical association X 2 Q06830 Q05086 affinity chromatography technology 20589759 physical association X 2 Q06830 Q05086 pull down 20589759 direct interaction X 2 Q06830 Q05086 enzymatic study 20589759 direct interaction X 2 A0A024RDL4 Q05086 affinity chromatography technology 16051665 physical association X 2 B4E2E2 Q05086 two hybrid 16713569 direct interaction X 2 B4E2E2 Q05086 two hybrid 24722188 direct interaction X 2 B4E2E2 Q05086 two hybrid 21900206 direct interaction X 2 Q99496 Q05086 enzymatic study 20351251 direct interaction X 2 Q99496 Q05086 affinity chromatography technology 20351251 physical association X 2 Q99496 Q05086 pull down 20351251 direct interaction X 2 Q56P03 Q05086 two hybrid 16713569 direct interaction X 2 A0A024R1N4 Q05086 affinity chromatography technology 16051665 physical association X 2 O75592 Q05086 affinity chromatography technology 16051665 physical association X 2 P17980 Q05086 enzymatic study 24743594 direct interaction X 2 Q16186 Q05086 enzymatic study 24743594 direct interaction X 2 P04278-3 Q05086 two hybrid 15862967 direct interaction X 2 Q9Y6Q9-5 Q05086 affinity chromatography technology 16951183 physical association X 2 Q9Y6Q9-5 Q05086 affinity chromatography technology 16951183 physical association X 2 O00487 Q05086 affinity chromatography technology 17323924 physical association X 2 O00487 Q05086 affinity chromatography technology 24743594 physical association X 2 O00487 Q05086 affinity chromatography technology 24743594 physical association X 2 Q9P2M4-2 Q05086 two hybrid 21900206 direct interaction X 2 P50222 Q05086 two hybrid 24722188 direct interaction X 2 P46527 Q05086 affinity chromatography technology 19591933 physical association X 2 P46527 Q05086 enzymatic study 19591933 direct interaction X 2 P29590-5 Q05086 enzymatic study 19325566 direct interaction X 2 P29590-5 Q05086 affinity chromatography technology 19325566 physical association X 2 P68133 Q05086 affinity chromatography technology 16051665 physical association X 2 Q549J4 Q05086 two hybrid 25416956 direct interaction X 2 Q13242 Q05086 biochemical 22939629 colocalization X 2 A0A024R8R4 Q05086 biochemical 22863883 colocalization X 2 P34932 Q05086 pull down 23040663 direct interaction X 2 P34932 Q05086 affinity chromatography technology 19233847 physical association X 2 P34932 Q05086 affinity chromatography technology 19233847 physical association X 2 P34932 Q05086 imaging technique 19233847 colocalization X 2 P62837 Q05086 pull down 19325566 direct interaction X 2 P62837 Q05086 pull down 24743594 direct interaction X 2 P62837 Q05086 enzymatic study 9990509 direct interaction X 2 P62837 Q05086 two hybrid 9182527 direct interaction X 2 P62837 Q05086 pull down 9182527 direct interaction X 2 Q6ULP2-5 Q05086 two hybrid 21900206 direct interaction X 2 P46019 Q05086 affinity chromatography technology 16051665 physical association X 2 A0A024R7G8 Q05086 affinity chromatography technology 19013454 physical association X 2 A0A024R7G8 Q05086 pull down 23671107 direct interaction X 2 A0A024R7G8 Q05086 enzymatic study 9153201 direct interaction X 2 A0A024R7G8 Q05086 pull down 10373495 direct interaction X 2 A0A024R7G8 Q05086 enzymatic study 10373495 direct interaction X 2 Q8IXH7 Q05086 two hybrid 21988832 direct interaction X 2 Q8IXH7 Q05086 pull down 17131388 direct interaction X 2 Q8IXH7 Q05086 affinity chromatography technology 17131388 physical association X 2 Q8IXH7 Q05086 enzymatic study 17131388 direct interaction X 2 A0A024R870 Q05086 biochemical 22863883 colocalization X 2 Q9H6R7 Q05086 affinity chromatography technology 16051665 physical association X 2 O15126 Q05086 two hybrid 16713569 direct interaction X 2 Q9H3U1-3 Q05086 biochemical 22939629 colocalization X 2 Q7LCB3 Q05086 affinity chromatography technology 25408199 physical association X 2 Q7LCB3 Q05086 affinity chromatography technology 17962381 physical association X 2 P54727 Q05086 pull down 10373495 direct interaction X 2 P54727 Q05086 enzymatic study 10373495 direct interaction X 2 P07355-2 Q05086 affinity chromatography technology 16051665 physical association X 2 Q32P28-2 Q05086 biochemical 22863883 colocalization X 2 Q05086 two hybrid 25416956 direct interaction X 2 Q05086 biochemical 22863883 colocalization X 2 A0A024R2K3 Q05086 pull down 8576257 direct interaction X 2 A0A024R2K3 Q05086 two hybrid 9153201 direct interaction X 2 A0A024R2K3 Q05086 pull down 9153201 direct interaction X 2 Q00987 Q05086 enzymatic study 11486026 direct interaction X 2 O43396 Q05086 biochemical 22939629 colocalization X 2 A0A024RCM3 Q05086 biochemical 22939629 colocalization X 2 O15116 Q05086 biochemical 22863883 colocalization X 2 A0A024R284 Q05086 two hybrid 10983987 direct interaction X 2 A0A024R284 Q05086 affinity chromatography technology 10983987 physical association X 2 D0PNI1 Q05086 two hybrid 21900206 direct interaction X 2 A0A024R730 Q05086 affinity chromatography technology 17110338 physical association X 2 A0A024R730 Q05086 imaging technique 19233847 colocalization X 2 Q9Y6B2 Q05086 two hybrid 21900206 direct interaction X 2 P07602-3 Q05086 two hybrid 21900206 direct interaction X 2 Q9UI26 Q05086 biochemical 22863883 colocalization X 2 Q9NR33 Q05086 two hybrid 21900206 direct interaction X 2 Q00613 Q05086 biochemical 22863883 colocalization X 2 Q05086 affinity chromatography technology 17108031 physical association X 2 Q05086 affinity chromatography technology 17108031 physical association X 2 Q05086 affinity chromatography technology 17108031 physical association X 2 Q05086 pull down 17108031 direct interaction X 2 Q05086 enzymatic study 17108031 direct interaction X 2 Q96CS3 Q05086 affinity chromatography technology 18775313 physical association X 2 Q2WGJ6 Q05086 two hybrid 25416956 direct interaction X 2 P00441 Q05086 pull down 23040663 direct interaction X 2 P04083 Q05086 pull down 19204938 direct interaction X 2 P04083 Q05086 affinity chromatography technology 19204938 physical association X 2 P04083 Q05086 affinity chromatography technology 19204938 physical association X 2 P04083 Q05086 enzymatic study 19204938 direct interaction X 2 P04083 Q05086 pull down 19204938 direct interaction X 2 Q93100-2 Q05086 affinity chromatography technology 16051665 physical association X 2 Q05086 two hybrid 10449731 direct interaction X 2 Q05086 pull down 10449731 direct interaction X 2 Q9Y242 Q05086 two hybrid 21900206 direct interaction X 2 Q15393 Q05086 biochemical 22939629 colocalization X 2 Q05086 Q05086 enzymatic study 15331633 direct interaction X 2 Q05086 Q05086 enzymatic study 9575161 direct interaction X 2 Q05086 Q05086 enzymatic study 22496338 direct interaction X 2 Q05086 P05067-7 pull down 21832049 direct interaction X 2 Q05086 biochemical 22939629 colocalization X 2 Q05086 Q9Y5L0-3 biochemical 22939629 colocalization X 2 Q05086 Q05086 pull down 24273172 direct interaction X 2 Q05086 Q05086 x-ray crystallography 24273172 association X 2 Q05086 enzymatic study 24743594 direct interaction X 2 Q05086 P51451 pull down 10449731 direct interaction X 2 Q05086 P51451 pull down 10449731 direct interaction X 2 Q05086 Q05086 enzymatic study 9688277 direct interaction X 2 Q9P0J0 Q05086 affinity chromatography technology 21765936 physical association X 2 Q9P0J0 Q05086 pull down 21765936 direct interaction X 2 Q05086 Q05086 enzymatic study 21033666 direct interaction X 2 A0A024R1N1 Q05086 affinity chromatography technology 16051665 physical association X 2 Q05086 affinity chromatography technology 16051665 physical association X 2 O43242 Q05086 affinity chromatography technology 16051665 physical association X 2 Q05086 Q9H9A7 two hybrid 21900206 direct interaction X 2 Q05086 Q04637-5 two hybrid 21900206 direct interaction X 2 P53804 Q05086 two hybrid 21900206 direct interaction X 2 Q9NZJ4 Q05086 pull down 23671107 direct interaction X 2 J3KNQ4 Q05086 two hybrid 21900206 direct interaction X 2 Q9Y4Y9-2 Q05086 biochemical 22939629 colocalization X 2 P62253 Q05086 pull down 17131388 direct interaction X 2 A0A024R539 Q05086 affinity chromatography technology 18775313 physical association X 2 O14933-2 Q05086 fluorescent resonance energy transfer 17433363 direct interaction X 2 O14933-2 Q05086 enzymatic study 9153201 direct interaction X 2 Q86YV5 Q05086 two hybrid 21900206 direct interaction X 2 D1MGQ2 Q05086 two hybrid 21900206 direct interaction X 2 B4DJ51 Q05086 affinity chromatography technology 16051665 physical association X 2 B4DJ51 Q05086 affinity chromatography technology 16051665 physical association X 2 Q6PJ69 Q05086 two hybrid 21900206 direct interaction X 2 Q01658 Q05086 biochemical 22863883 colocalization X 2 B4DUF9 Q05086 biochemical 22863883 colocalization X 2 Q05086 two hybrid 21900206 direct interaction X 2 P0CG47 Q05086 two hybrid 25416956 direct interaction X 2 Q05086 coimmunoprecipitation 10983987 association C 6 P10276 Q05086 biochemical 9891052 physical association X 2 A0A024R1A4 Q05086 x-ray crystallography 10558980 direct interaction X 2 A0A024R1A4 Q05086 fluorescence polarization spectroscopy 16142244 direct interaction X 2 F1D8N4 Q05086 biochemical 9891052 physical association X 2 Q05086 P62987 comigration in sds page 21532592 direct interaction X 2 P10275 Q05086 biochemical 9891052 physical association X 2 Q05086 biochemical 9891052 physical association X 2 P03126 Q05086 pull down 22483108 direct interaction X 2 P06401 Q05086 two hybrid 9891052 physical association X 2 Q05086 anti tag coimmunoprecipitation 18775313 association C 13 Q05086 anti tag coimmunoprecipitation 18775313 association C 13 Q05086 anti tag coimmunoprecipitation 24811749 association C 6 Q05086 anti tag coimmunoprecipitation 24811749 association C 66 Q05086 ubiquitinase assay 25260751 ubiquitination reaction C 4 Q04637 Q05086 two hybrid 21900206 physical association X 2 Q05086 surface plasmon resonance 16493710 physical association C 3 P10276 Q05086 two hybrid array 16713569 physical association X 2 P06931 Q05086 pull down 7624774 direct interaction X 2 P06931 Q05086 two hybrid 9467941 physical association X 2 P06463 Q05086 surface plasmon resonance 16493710 physical association X 2 P06463 Q05086 pull down 7624774 direct interaction X 2 Q5JPE7 Q05086 two hybrid 21900206 physical association X 2 A0A024R1A4 Q05086 x-ray crystallography 10558980 direct interaction X 2 P62258 Q05086 two hybrid 21900206 physical association X 2 Q03701 Q05086 two hybrid 21900206 physical association X 2 P17386 Q05086 pull down 7624774 direct interaction X 2 Q9UM19 Q05086 two hybrid 21900206 physical association X 2 A0A024RB59 Q05086 two hybrid 21900206 physical association X 2 A0A024QZQ2 Q05086 two hybrid 21900206 physical association X 2 Q77E16 Q05086 coimmunoprecipitation 17023019 physical association X 2 Q77E16 Q05086 mass spectrometry studies of complexes 17023019 physical association X 2 Q77E16 Q05086 tandem affinity purification 17166906 physical association X 2 P55854 Q05086 two hybrid 21900206 physical association X 2 Q05086 Q14160 pull down 11027293 ubiquitination reaction X 2 B9UPE7 Q05086 coimmunoprecipitation 17023019 physical association X 2 B9UPE7 Q05086 mass spectrometry studies of complexes 17023019 physical association X 2 B9UPE7 Q05086 two hybrid 17023019 physical association X 2 Q56P03 Q05086 two hybrid array 16713569 physical association X 2 K7PPA8 Q05086 surface plasmon resonance 16493710 physical association X 2 Q05086 pull down 12620801 association C 4 Q05086 pull down 12620801 association C 4 Q05086 anti tag coimmunoprecipitation 24811749 association C 10 Q05086 anti bait coimmunoprecipitation 17110338 association C 28 P06933 Q05086 two hybrid 9467941 physical association X 2 Q6ULP2 Q05086 two hybrid 21900206 physical association X 2 O15126 Q05086 two hybrid array 16713569 physical association X 2 P03126 Q05086 pull down 11027293 physical association X 2 P03126 Q05086 pull down 7624774 direct interaction X 2 P03126 Q05086 two hybrid 9467941 physical association X 2 D0PNI1 Q05086 two hybrid 21900206 physical association X 2 Q9Y6B2 Q05086 two hybrid 21900206 physical association X 2 Q9NR33 Q05086 two hybrid 21900206 physical association X 2 Q16611 Q05086 anti tag coimmunoprecipitation 9881696 physical association X 2 Q16611 Q05086 pull down 9881696 direct interaction X 2 Q9Y242 Q05086 two hybrid 21900206 physical association X 2 Q05086 P36799 surface plasmon resonance 15890204 physical association X 2 Q05086 Q9H9A7 two hybrid 21900206 physical association X 2 P53804 Q05086 two hybrid 21900206 physical association X 2 Q9NVD7 Q05086 two hybrid 21900206 physical association X 2 Q6IE81 Q05086 two hybrid array 16713569 physical association X 2 Q6IE81 Q05086 two hybrid 21900206 physical association X 2 Q86YV5 Q05086 two hybrid 21900206 physical association X 2 D1MGQ2 Q05086 two hybrid 21900206 physical association X 2 Q6PJ69 Q05086 two hybrid 21900206 physical association X 2 Q9H6J7 Q05086 two hybrid 21900206 physical association X 2 Q9P2M4 Q05086 two hybrid 21900206 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B UBE3A AFTPH MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_156556|UniProt_157769|UniProt_178367 bait|bait|bait prey|prey|prey TTC3 UBE3A MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|(biogrid) UniProt_178386|UniProt_157788|BIOGRID_156560 prey|prey|prey bait|bait|bait UBE3A METTL1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304762 prey bait CDKN1B UBE3A MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19591933 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_140657|BIOGRID_140656 prey|bait bait|prey UBE3A UBQLN2 MI:0493(in vivo)|MI:0493(in vivo)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 10983987 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|-|MI:0403(colocalization)|MI:0407(direct interaction)|MI:0915(physical association) MI:0468(hprd)|MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid) HPRD_40474|HPRD_5476|BIOGRID_114125|BIOGRID_77600|BIOGRID_114128 -|-|bait|bait|bait -|-|prey|prey|prey UBE3A IPO11 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_300598 bait prey UBE3A DBNL MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304758 prey bait UBE3A LRSAM1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304761 prey bait ANXA1 UBE3A MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down) 19204938 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_145836|BIOGRID_145834|BIOGRID_145835|BIOGRID_145839|BIOGRID_145840 prey|prey|bait|prey|bait bait|bait|prey|bait|prey PDE1B UBE3A MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_156541|UniProt_157778|UniProt_178376 prey|prey|prey bait|bait|bait UBE3A NOMO2 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|(biogrid) UniProt_178374|UniProt_157776|BIOGRID_156540 bait|bait|bait prey|prey|prey UBE2D3 UBE3A MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0493(in vivo) 11486026,9990509 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|- (biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_225635|BIOGRID_92726|HPRD_9449 prey|bait|- bait|prey|- UBE2G2 UBE3A MI:0492(in vitro) 10558980 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_9450 - - UBE3A UFD1L MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_241382 bait prey SOD1 UBE3A MI:0096(pull down) 23040663 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_217859 prey bait UBE3A ESR2 MI:0004(affinity chromatography technology) 17962381 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_117801 prey bait SMAD9 UBE3A MI:0018(two hybrid) 15231748 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_2706 - - UBE2L6 UBE3A MI:0492(in vitro)|MI:0055(fluorescent resonance energy transfer) 10558980,17433363 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction) MI:0468(hprd)|(biogrid) HPRD_9452|BIOGRID_207384 -|prey -|bait UBE3A SGK223 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|(intact) UniProt_157781|BIOGRID_156547|UniProt_178379 bait|bait|bait prey|prey|prey SHBG UBE3A MI:0018(two hybrid)|MI:0018(two hybrid) 15862967 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction) MI:0468(hprd)|(biogrid) HPRD_18224|BIOGRID_211105 -|bait -|prey RAD23B UBE3A MI:0096(pull down)|MI:0096(pull down) 10373495 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_138664|BIOGRID_138662 prey|bait bait|prey MYCBP2 UBE3A MI:0004(affinity chromatography technology) 16051665 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_148529 prey bait CEBPA UBE3A MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 23598402 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_273040|BIOGRID_273043|BIOGRID_273041 bait|prey|bait prey|bait|prey EIF4G1 UBE3A MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|(intact) UniProt_178371|BIOGRID_156555|UniProt_157773 prey|prey|prey bait|bait|bait UBE3A GOLGA3 MI:0004(affinity chromatography technology) 16051665 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_148530 bait prey UBE3A LEPRE1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304759 prey bait PSAP UBE3A MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|(biogrid) UniProt_178380|UniProt_157782|BIOGRID_156561 prey|prey|prey bait|bait|bait HERC2 UBE3A MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21493713,22645313 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association)|MI:0403(colocalization)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_187931|BIOGRID_197711|BIOGRID_187935|BIOGRID_197709 prey|prey|prey|prey bait|bait|bait|bait HSF1 UBE3A MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_300361 prey bait AR UBE3A MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0492(in vitro) 16254014,9891052 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|- (biogrid)|MI:0465(dip)|MI:0468(hprd) BIOGRID_245112|DIP_52995|HPRD_25288 prey|-|- bait|-|- TSC2 UBE3A MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down) 15175323,18298802 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_117387|BIOGRID_117386|BIOGRID_102760 prey|bait|prey bait|prey|bait PGR UBE3A MI:0492(in vitro)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 9891052 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(biogrid)|MI:0465(dip) HPRD_9453|BIOGRID_105741|BIOGRID_77803|DIP_52993 -|bait|bait|- -|prey|prey|- UBC UBE3A MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology) 20639865,20972266,21139048,21493713,21890473,21906983,21963094,21987572,22053931,22118674,22505724,23000965,23439649,9575161 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_160075|BIOGRID_166390|BIOGRID_197710|BIOGRID_179294|BIOGRID_170024|BIOGRID_164179|BIOGRID_222288|BIOGRID_172834|BIOGRID_258349|BIOGRID_163194|BIOGRID_208426|BIOGRID_268933|BIOGRID_160338|BIOGRID_225045 bait|bait|prey|bait|bait|bait|bait|bait|prey|bait|prey|bait|bait|bait prey|prey|bait|prey|prey|prey|prey|prey|bait|prey|bait|prey|prey|prey UBE3A PHKB MI:0004(affinity chromatography technology) 16051665 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_148532 bait prey UBE3A PARVA MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|(biogrid) UniProt_178375|UniProt_157777|BIOGRID_156545 bait|bait|bait prey|prey|prey UBE3A LPP MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304760 prey bait LSM1 UBE3A MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_300980 prey bait LCK UBE3A MI:0018(two hybrid)|MI:0018(two hybrid) 10449731 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_99189|BIOGRID_99190 prey|prey bait|bait UBE3A POLE4 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|(biogrid) UniProt_157780|UniProt_178378|BIOGRID_156552 bait|bait|bait prey|prey|prey PTPN3 UBE3A MI:0004(affinity chromatography technology) 17166906 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_283556 prey bait APP UBE3A MI:0096(pull down) 21832049 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_229138 prey bait SUMO3 UBE3A MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|(intact) UniProt_178382|BIOGRID_156543|UniProt_157784 prey|prey|prey bait|bait|bait HBA1; UBE3A MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|(biogrid) UniProt_178372|UniProt_157774|BIOGRID_156554 prey|prey|prey bait|bait|bait PML UBE3A MI:0415(enzymatic study)|MI:0415(enzymatic study) 19325566 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_153106|BIOGRID_153108 prey|bait bait|prey UBE3A TH1L MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0397(two hybrid array)|MI:0096(pull down)|MI:0096(pull down) 17131388,21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(intact)|(biogrid)|(biogrid) BIOGRID_140789|BIOGRID_286211|UniProt_119858|BIOGRID_140790|BIOGRID_140793 prey|prey|unspecified role|prey|bait bait|bait|unspecified role|bait|prey UBE3A ASPM MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21633703 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_211240|BIOGRID_211238|BIOGRID_211239 prey|bait|bait bait|prey|prey UBE3A EAPP MI:0018(two hybrid)|MI:0096(pull down)|MI:0397(two hybrid array)|MI:0096(pull down)|MI:0018(two hybrid) 16713569 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0468(hprd)|MI:0471(mint)|(intact)|MI:0471(mint)|(biogrid) HPRD_26145|MINT_50773|UniProt_85825|MINT_83061|BIOGRID_215405 -|bait|prey|bait|bait -|prey|bait|prey|prey UBE3A UBQLN1 MI:0493(in vivo)|MI:0018(two hybrid)|MI:0018(two hybrid) 10983987 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(biogrid) HPRD_40474|BIOGRID_114124|BIOGRID_114127 -|bait|prey -|prey|bait UBXN1 UBE3A MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 18775313 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0915(physical association) (intact)|(intact)|(biogrid) UniProt_183214|UniProt_97410|BIOGRID_149390 bait|bait|bait prey|prey|prey NR3C1 UBE3A MI:0018(two hybrid) 9891052 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) MI:0465(dip) DIP_52996 - - UBE3A HPCAL4 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|(intact) UniProt_178373|BIOGRID_156549|UniProt_157775 bait|bait|bait prey|prey|prey UBE3A ARC MI:0096(pull down) 23671107 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_282412 prey bait PHKG2 UBE3A MI:0004(affinity chromatography technology) 16051665 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_148535 prey bait ARPC1B UBE3A MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304756 bait prey UBE3A UNC45A MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_238370 bait prey SCAMP1 UBE3A MI:0096(pull down)|MI:0018(two hybrid)|MI:0397(two hybrid array)|MI:0018(two hybrid)|MI:0096(pull down) 16713569 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0471(mint)|MI:0468(hprd)|(intact)|(biogrid)|MI:0471(mint) MINT_50467|HPRD_26304|UniProt_85827|BIOGRID_215408|MINT_82755 prey|-|bait|prey|prey bait|-|prey|bait|bait RARA UBE3A MI:0096(pull down)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0397(two hybrid array)|MI:0018(two hybrid)|MI:0018(two hybrid) 16713569,9891052 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint)|MI:0468(hprd)|(intact)|(biogrid)|MI:0465(dip) MINT_82569|MINT_50281|HPRD_12253|UniProt_85826|BIOGRID_215407|DIP_52997 prey|prey|-|bait|prey|- bait|bait|-|prey|bait|- UBE3A TCF19 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|(intact) UniProt_178384|BIOGRID_156548|UniProt_157786 bait|bait|bait prey|prey|prey UBE3A NEURL4 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22645313 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_187934|BIOGRID_187930 bait|bait prey|prey UBE3A BTF3L4 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304757 prey bait UBE3A PHKG1 MI:0004(affinity chromatography technology) 16051665 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_148599 bait prey UBE3A LSM5 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_242275 prey bait UBE3A TNPO3 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_243935 prey bait RAD23A UBE3A MI:0415(enzymatic study)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down) 10373495,19013454,23671107 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_188749|BIOGRID_282410|BIOGRID_138663|BIOGRID_138661 bait|bait|prey|bait prey|prey|bait|prey ACTA1 UBE3A MI:0004(affinity chromatography technology) 16051665 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_148526 prey bait HSPA4 UBE3A MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology) 19233847,23040663 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_149708|BIOGRID_149704|BIOGRID_217860|BIOGRID_149705 prey|prey|prey|bait bait|bait|bait|prey HSPA8 UBE3A MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19233847 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_149707|BIOGRID_149706 bait|prey prey|bait UBE3A C11orf49 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|(intact) UniProt_157770|BIOGRID_156544|UniProt_178368 bait|bait|bait prey|prey|prey UBE3A C2orf44 MI:0004(affinity chromatography technology) 16051665 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_148533 bait prey CEBPZ UBE3A MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|(biogrid) UniProt_157771|UniProt_178369|BIOGRID_156558 prey|prey|prey bait|bait|bait UBE3A FAF2 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 18775313 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association)|MI:0914(association) (biogrid)|(intact)|(intact) BIOGRID_149351|UniProt_183212|UniProt_97408 prey|prey|prey bait|bait|bait UBD UBE3A MI:0004(affinity chromatography technology) 22797925 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_226643 bait prey UBE3A BAK1 MI:0006(anti bait coimmunoprecipitation)|MI:0096(pull down)|MI:0096(pull down)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 9881696 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction) MI:0471(mint)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint) MINT_70152|UniProt_136177|UniProt_136175|MINT_40702|MINT_40703|MINT_70151 prey|prey|bait|bait|prey|bait bait|bait|prey|prey|bait|prey UBE3A MAPK6 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22645313 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_187932|BIOGRID_187928 bait|bait prey|prey UBE3A PRDX1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20589759 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_149753|BIOGRID_149755|BIOGRID_149752 prey|bait|bait bait|prey|prey MYH9 UBE3A MI:0004(affinity chromatography technology) 16051665 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_148524 prey bait UBE3A RMI1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|(biogrid) UniProt_157783|UniProt_178381|BIOGRID_156550 bait|bait|bait prey|prey|prey TXNL1 UBE3A MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_236125 bait prey UBE2G1 UBE3A MI:0096(pull down)|MI:0492(in vitro) 10558980,17131388 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_221573|HPRD_9343 prey|- bait|- PHKA2 UBE3A MI:0004(affinity chromatography technology) 16051665 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_148531 prey bait UBE3A TRIM65 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|(biogrid) UniProt_178385|UniProt_157787|BIOGRID_156551 bait|bait|bait prey|prey|prey YWHAZ UBE3A MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_156559|UniProt_178388|UniProt_157790 prey|prey|prey bait|bait|bait BPY2 UBE3A MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 12207887 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0407(direct interaction)|-|- (biogrid)|MI:0468(hprd)|(biogrid)|MI:0468(hprd)|MI:0468(hprd) BIOGRID_107765|HPRD_9456|BIOGRID_77645|HPRD_9454|HPRD_6007 bait|-|bait|-|- prey|-|prey|-|- PSMD4 UBE3A MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study) 19240029,22350919,22645313 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0403(colocalization)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_149304|BIOGRID_187936|BIOGRID_208179 prey|prey|prey bait|bait|bait p53 UBE3A MI:0004(affinity chromatography technology)|MI:0107(surface plasmon resonance)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down)|MI:0493(in vivo)|MI:0096(pull down)|MI:0096(pull down)|MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0096(pull down)|MI:0096(pull down)|MI:0107(surface plasmon resonance) 11027293,12620801,15001357,16493710,17131388,19364824,23040663,8090726,8380895,9369221,9688277 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0914(association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|-|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0914(association)|MI:0914(association)|MI:0915(physical association) (biogrid)|(intact)|(biogrid)|(biogrid)|(intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0471(mint)|MI:0471(mint)|(intact) BIOGRID_259475|UniProt_84210|BIOGRID_139839|BIOGRID_259471|UniProt_73157|BIOGRID_257623|BIOGRID_259473|BIOGRID_217861|BIOGRID_140791|HPRD_4487|BIOGRID_139853|BIOGRID_207738|BIOGRID_164639|BIOGRID_225898|MINT_66136|MINT_36972|UniProt_84209 prey|prey|bait|prey|prey|prey|prey|prey|bait|-|bait|prey|prey|prey|prey|prey|prey bait|bait|prey|bait|bait|bait|bait|bait|prey|-|prey|bait|bait|bait|prey|prey|bait UBE3A TBC1D14 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|(intact) UniProt_178383|BIOGRID_156557|UniProt_157785 bait|bait|bait prey|prey|prey UBE3A NCOA3 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16951183 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_185396|BIOGRID_185395 prey|bait bait|prey UBE3A EID1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|(biogrid) UniProt_157772|UniProt_178370|BIOGRID_156542 bait|bait|bait prey|prey|prey UBE3A NDUFA13 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21765936 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_141761|BIOGRID_141760 prey|prey bait|bait CFTR UBE3A MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation) 17110338,19233847 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0403(colocalization)|MI:0914(association) (biogrid)|(biogrid)|(intact) BIOGRID_262806|BIOGRID_149709|UniProt_87502 bait|prey|bait prey|bait|prey BLK UBE3A MI:0018(two hybrid)|MI:0493(in vivo)|MI:0018(two hybrid) 10449731 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|-|MI:0407(direct interaction) (biogrid)|MI:0468(hprd)|(biogrid) BIOGRID_99191|HPRD_4658|BIOGRID_99192 prey|-|bait bait|-|prey UBE3A SACS MI:0096(pull down) 23671107 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_282411 prey bait UBE3A HIF1AN MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22645313 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_187933|BIOGRID_187929 bait|bait prey|prey DR1 UBE3A MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_299405 prey bait UBE3A NPLOC4 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304763 prey bait MDM2 UBE3A MI:0415(enzymatic study) 11486026 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_225636 prey bait UBE3A SF3B3 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_237749 prey bait YWHAE UBE3A MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_156546|UniProt_178387|UniProt_157789 prey|prey|prey bait|bait|bait BRCA1 UBE3A MI:0096(pull down) 12890688 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_85198 bait prey PSMD3 UBE3A MI:0004(affinity chromatography technology) 16051665 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_148534 prey bait UBE2D1 UBE3A MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0492(in vitro)|MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0096(pull down) 10066826,15001357,8090726,8576257,9575161 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|-|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid) BIOGRID_113064|BIOGRID_225897|HPRD_9448|BIOGRID_92729|BIOGRID_225957|BIOGRID_225945 bait|prey|-|bait|prey|prey prey|bait|-|prey|bait|bait UBE3A PHF17 MI:0018(two hybrid)|MI:0397(two hybrid array)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down) 16713569,21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact)|(intact)|MI:0471(mint)|MI:0468(hprd)|(intact)|(biogrid)|MI:0471(mint) BIOGRID_215406|UniProt_85909|UniProt_157779|MINT_83144|HPRD_26156|UniProt_178377|BIOGRID_156553|MINT_50856 bait|bait|bait|bait|-|bait|bait|bait prey|prey|prey|prey|-|prey|prey|prey UBE3A DDX39B MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_242973 prey bait ARHGEF15 UBE3A MI:0004(affinity chromatography technology) 21029865 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_154810 prey bait UBE3A BARD1 MI:0096(pull down) 12890688 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_85833 prey bait ESR1 UBE3A MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid) 16314411,22865929,9891052 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|MI:0465(dip) BIOGRID_126176|BIOGRID_197147|DIP_52994 bait|prey|- prey|bait|- UBE3A SCRIB MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down) 11027293,16482544 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0220(ubiquitination reaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(intact)|(biogrid)|(biogrid)|(biogrid) BIOGRID_259474|UniProt_69073|BIOGRID_259476|BIOGRID_259477|BIOGRID_139956 bait|bait|bait|prey|bait prey|neutral component|prey|bait|prey UBE3A RNF2 MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0415(enzymatic study) 20351251 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_138629|BIOGRID_138628|BIOGRID_138627 bait|prey|bait prey|bait|prey XRCC6 UBE3A MI:0004(affinity chromatography technology) 16051665 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_148525 prey bait UBE2D2 UBE3A MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0018(two hybrid)|MI:0018(two hybrid) 19325566,9182527,9990509 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_226109|BIOGRID_92725|BIOGRID_102903|BIOGRID_102904 prey|bait|prey|prey bait|prey|bait|bait UBE3A DLG1 MI:0096(pull down) 16482544 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_139955 bait prey USP14 UBE3A MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_238369 prey bait UBE2L3 UBE3A MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0055(fluorescent resonance energy transfer)|MI:0114(x-ray crystallography)|MI:0415(enzymatic study)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0055(fluorescent resonance energy transfer)|MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0492(in vitro) 10373495,10558980,11027293,11431533,17433363,17603074,19204938,19364824,19591933,19899154,20351251,20589759,22350887,8576257,9575161,9688277,9990509 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0914(association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|- (biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0465(dip)|(biogrid)|(intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_92728|BIOGRID_225921|BIOGRID_92727|BIOGRID_207385|DIP_53056|BIOGRID_225958|UniProt_65987|BIOGRID_108588|BIOGRID_225920|BIOGRID_225929|BIOGRID_221571|BIOGRID_137387|BIOGRID_196787|BIOGRID_221560|BIOGRID_108469|BIOGRID_207383|BIOGRID_200489|BIOGRID_223161|BIOGRID_222958|BIOGRID_226104|BIOGRID_310042|BIOGRID_197208|HPRD_9451 bait|prey|bait|prey|-|prey|neutral component|prey|prey|prey|prey|prey|bait|prey|prey|prey|bait|prey|prey|prey|prey|prey|- prey|bait|prey|bait|-|bait|neutral component|bait|bait|bait|bait|bait|prey|bait|bait|bait|prey|bait|bait|bait|bait|bait|- MCM7 UBE3A MI:0493(in vivo)|MI:0096(pull down)|MI:0096(pull down) 9852095 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(biogrid) HPRD_37640|BIOGRID_106928|BIOGRID_106929 -|bait|bait -|prey|prey ANXA2 UBE3A MI:0004(affinity chromatography technology) 16051665 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_148527 prey bait CALM1 UBE3A MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16051665 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_148536|BIOGRID_148598 prey|prey bait|bait UBE2E1 UBE3A MI:0492(in vitro) 8576257 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_9447 - - UBE3A SRSF9 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_241778 prey bait

PPI - HINT Gene A Gene B PMID Method Quality ARNTL UBE3A 25660546,24728990 0004,0004 LC PSMD14 UBE3A 26496610,17323924,26496610,24743594 0007,0004,0004,0004 HT,LC LSM1 UBE3A 22863883 0401 HT ARPC1B UBE3A 22863883 0401 HT HERC2 UBE3A 21493713,22645313,22645313,25476789,21493713 0401,0004,0401,0004,0004 LC ESR1 UBE3A 22865929,16314411,9891052 0004,0004,0401 LC TP53 UBE3A 9688277,12620801,17131388,8380895 0096,0096,0004,0096 LC UBC UBE3A 20972266,21963094,20639865,22118674,21493713 0004,0004,0004,0004,0004 LC AR UBE3A 9891052,16254014,9891052 0018,0004,0401 LC CFTR UBE3A 17110338,17110338,19233847 0004,0006,0428 LC HSPA4 UBE3A 23040663,19233847,19233847 0096,0428,0004 LC MAGEA1 UBE3A 26186194 0004 HT TSC2 UBE3A 15175323,18298802,18298802 0096,0096,0004 LC UBE2D1 UBE3A 8090726,15001357,8576257,17426036,19240029,24743594,9575161,8576257,9450543 0096,0096,0096,0096,0096,0096,0096,0415,0096 LC UBE2E1 UBE3A 9153201,8576257,9153201 0096,0096,0018 LC USP14 UBE3A 22939629 0401 HT RAD23A UBE3A 10373495,10373495,19013454,23671107 0096,0415,0004,0096 LC PSMD4 UBE3A 25633294,22645313 0096,0401 LC UBE2D3 UBE3A 24743594,11486026 0096,0096 LC CALM1|CALM2|CALM3 UBE3A 16051665,26506232 0004,0096 LC PSMC1 UBE3A 26496610,26496610 0007,0004 HT UBE2D2 UBE3A 19325566,9182527,7724550,9182527,26216987,24743594 0096,0096,0096,0018,0096,0096 LC UBE2L3 UBE3A 20589759,17603074,10558980,17433363,22350887,8576257,10373495,19899154,11431533,22350887,11027293,9153201,9688277,17131388,19364824,20351251,9153201,10558980,8576257,19204938,26216987,10558980,9575161,19591933,10558980,8576257,17433363 0096,0096,0018,0096,0415,0018,0096,0096,0004,0096,0096,0096,0096,0096,0096,0096,0018,0096,0096,0096,0096,0114,0096,0096,0415,0415,0055 LC HSF1 UBE3A 22863883 0401 HT PLAUR UBE3A 26186194 0004 HT UBE3A UBE3A 24273172,12620801,24273172,26506232 0114,0096,0096,0096 LC UBE3A SRSF9 22939629 0401 HT UBE3A DDX39B 22939629 0401 HT UBE3A SCRIB 11027293,16482544,11027293 0096,0096,0415 LC UBE3A SF3B3 22939629 0401 HT UBE3A MAPK6 26972000,22645313,22645313 0007,0004,0401 LC UBE3A P3H1 22863883 0401 HT UBE3A Q53GA5 9688277,26789255,11027293,17131388,26789255,1661671,23040663,16493710,11027293,11027293,8380895 0096,0004,0004,0004,0114,0096,0096,0096,0096,0415,0096 LC UBE3A DKFZP666G145 22863883 0401 HT UBE3A ELA2B 26186194 0004 HT UBE3A LRSAM1 22863883 0401 HT UBE3A NPLOC4 22863883 0401 HT UBE3A ESR2 17962381,25408199 0004,0004 LC UBE3A UFD1L 22939629 0401 HT UBE3A LPP 22863883 0401 HT UBE3A BTF3L4 22863883 0401 HT UBE3A UNC45A 22939629 0401 HT UBE3A TRPV5 26186194 0004 HT UBE3A METTL1 22863883 0401 HT UBE3A Q9UBT1 22865929,16314411 0004,0004 LC UBE3A IPO11 22863883 0401 HT UBE3A DBNL 22863883 0401 HT UBE3A LSM5 22939629 0401 HT UBE3A UCHL5 26186194 0004 HT UBE3A TNPO3 22939629 0401 HT UBE3A SRPRB 26186194 0004 HT UBE3A HEL-S-114 22939629 0401 HT PSMD14 UBE3A 26496610,26496610 0007,0004 HT LSM1 UBE3A 22863883 0401 HT ARPC1B UBE3A 22863883 0401 HT MAGEA1 UBE3A 26186194 0004 HT USP14 UBE3A 22939629 0401 HT PSMC1 UBE3A 26496610,26496610 0007,0004 HT HSF1 UBE3A 22863883 0401 HT PLAUR UBE3A 26186194 0004 HT UBE3A SRSF9 22939629 0401 HT UBE3A DDX39B 22939629 0401 HT UBE3A SF3B3 22939629 0401 HT UBE3A P3H1 22863883 0401 HT UBE3A DKFZP666G145 22863883 0401 HT UBE3A ELA2B 26186194 0004 HT UBE3A LRSAM1 22863883 0401 HT UBE3A NPLOC4 22863883 0401 HT UBE3A UFD1L 22939629 0401 HT UBE3A LPP 22863883 0401 HT UBE3A BTF3L4 22863883 0401 HT UBE3A UNC45A 22939629 0401 HT UBE3A TRPV5 26186194 0004 HT UBE3A METTL1 22863883 0401 HT UBE3A IPO11 22863883 0401 HT UBE3A DBNL 22863883 0401 HT UBE3A LSM5 22939629 0401 HT UBE3A UCHL5 26186194 0004 HT UBE3A TNPO3 22939629 0401 HT UBE3A SRPRB 26186194 0004 HT UBE3A HEL-S-114 22939629 0401 HT ARNTL UBE3A 25660546,24728990 0004,0004 LC PSMD14 UBE3A 17323924,24743594 0004,0004 LC HERC2 UBE3A 21493713,22645313,22645313,25476789,21493713 0401,0004,0401,0004,0004 LC ESR1 UBE3A 22865929,16314411,9891052 0004,0004,0401 LC TP53 UBE3A 9688277,12620801,17131388,8380895 0096,0096,0004,0096 LC UBC UBE3A 20972266,21963094,20639865,22118674,21493713 0004,0004,0004,0004,0004 LC AR UBE3A 9891052,16254014,9891052 0018,0004,0401 LC CFTR UBE3A 17110338,17110338,19233847 0004,0006,0428 LC HSPA4 UBE3A 23040663,19233847,19233847 0096,0428,0004 LC TSC2 UBE3A 15175323,18298802,18298802 0096,0096,0004 LC UBE2D1 UBE3A 8090726,15001357,8576257,17426036,19240029,24743594,9575161,8576257,9450543 0096,0096,0096,0096,0096,0096,0096,0415,0096 LC UBE2E1 UBE3A 9153201,8576257,9153201 0096,0096,0018 LC RAD23A UBE3A 10373495,10373495,19013454,23671107 0096,0415,0004,0096 LC PSMD4 UBE3A 25633294,22645313 0096,0401 LC UBE2D3 UBE3A 24743594,11486026 0096,0096 LC CALM1|CALM2|CALM3 UBE3A 16051665,26506232 0004,0096 LC UBE2D2 UBE3A 19325566,9182527,7724550,9182527,26216987,24743594 0096,0096,0096,0018,0096,0096 LC UBE2L3 UBE3A 20589759,17603074,10558980,17433363,22350887,8576257,10373495,19899154,11431533,22350887,11027293,9153201,9688277,17131388,19364824,20351251,9153201,10558980,8576257,19204938,26216987,10558980,9575161,19591933,10558980,8576257,17433363 0096,0096,0018,0096,0415,0018,0096,0096,0004,0096,0096,0096,0096,0096,0096,0096,0018,0096,0096,0096,0096,0114,0096,0096,0415,0415,0055 LC UBE3A UBE3A 24273172,12620801,24273172,26506232 0114,0096,0096,0096 LC UBE3A SCRIB 11027293,16482544,11027293 0096,0096,0415 LC UBE3A MAPK6 26972000,22645313,22645313 0007,0004,0401 LC UBE3A Q53GA5 9688277,26789255,11027293,17131388,26789255,1661671,23040663,16493710,11027293,11027293,8380895 0096,0004,0004,0004,0114,0096,0096,0096,0096,0415,0096 LC UBE3A ESR2 17962381,25408199 0004,0004 LC UBE3A Q9UBT1 22865929,16314411 0004,0004 LC B3KPL7 UBE3A 25416956,25416956,25416956 1112,0397,1356 HT NR3C4 UBE3A 9891052 0018 LC BPY2|BPY2B|BPY2C UBE3A 12207887,12207887 0004,0018 LC UBE2L6 UBE3A 10558980,9153201,9153201,17433363 0018,0018,0415,0055 LC LSM1 UBE3A 22863883 0401 LC SCAMP1 UBE3A 16713569,16713569 0397,0018 HT ARPC1B UBE3A 22863883 0401 LC SMAD9 UBE3A 15231748 0018 HT HERC2 UBE3A 21493713,22645313,22645313,21493713 0401,0004,0401,0004 LC ESR1 UBE3A 9891052 0401 LC ANXA1 UBE3A 19204938,19204938,19204938 0096,0415,0004 LC NR3C1 UBE3A 9891052 0401 LC SHBG UBE3A 15862967 0018 LC TP53 UBE3A 19364824,16493710 0415,0107 LC LCK UBE3A 10449731,10449731 0096,0018 LC PGR UBE3A 9891052,9891052 0018,0096 LC PSAP UBE3A 21900206 0018 HT UBB UBE3A 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT UBC UBE3A 23439649,21532592,9575161 0415,0808,0415 LC AR UBE3A 9891052,9891052 0018,0401 LC RARA UBE3A 16713569,9891052,16713569 0397,0401,0018 HT,LC TAT UBE3A 25416956,25416956,25416956,25416956,24722188 1356,1112,0397,0018,0018 HT PSMC3 UBE3A 24743594 0415 LC PML UBE3A 19325566,19325566 0415,0004 LC MAGEA8 UBE3A 24722188 0018 HT CDKN1B UBE3A 19591933,19591933 0415,0004 LC MEOX2 UBE3A 24722188 0018 HT UBE2D1 UBE3A 8576257,14517261,8576257,10066826 0096,0415,0415,0415 LC UBE2E1 UBE3A 9153201,9153201 0096,0018 LC TTC3 UBE3A 21900206 0018 HT USP14 UBE3A 22939629 0401 LC RAD23A UBE3A 10373495,17426036,10373495,26216987,9153201 0096,0415,0415,0415,0415 LC RAD23B UBE3A 10373495,10373495 0415,0096 LC PSMD4 UBE3A 22645313,19240029,24743594,22350919 0401,0415,0415,0415 LC SUMO3 UBE3A 21900206 0018 HT UBE2D3 UBE3A 9990509 0415 LC YWHAE UBE3A 21900206 0018 HT UBE2D2 UBE3A 9990509,9182527,9182527 0415,0096,0018 LC UBA52 UBE3A 21532592 0808 LC YWHAZ UBE3A 21900206 0018 HT UBE2L3 UBE3A 10558980,17433363,22350887,8576257,22350887,9153201,16142244,9153201,10558980,8576257,9990509,10558980,10558980,16142244,8576257,17433363 0018,0096,0415,0018,0096,0096,0045,0018,0096,0096,0415,0114,0415,0053,0415,0055 LC HBA1|HBA2 UBE3A 21900206 0018 HT HSF1 UBE3A 22863883 0401 LC MDM2 UBE3A 11486026 0415 LC PDE1B UBE3A 21900206 0018 HT CEBPZ UBE3A 21900206 0018 HT EIF4G1 UBE3A 21900206 0018 HT UBE3A UBE3A 24273172,22496338,10558980,17426036,9575161,21033666,26216987,9688277,24273172,15331633 0114,0415,0114,0415,0415,0415,0415,0415,0096,0415 LC UBE3A PRDX1 20589759,20589759,20589759 0004,0096,0415 LC UBE3A SRSF9 22939629 0401 LC UBE3A UBE2V1 25260751 0997 LC UBE3A DDX39B 22939629 0401 LC UBE3A SCRIB 11027293,11027293 0096,0415 LC UBE3A SF3B3 22939629 0401 LC UBE3A ADRM1 24743594 0415 LC UBE3A MAPK6 22645313,22645313 0004,0401 LC UBE3A KLHL38 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT UBE3A P3H1 22863883 0401 LC UBE3A Q53GA5 26789255,19364824,11027293,26789255,7724550,15001357,8090726,7708685,9450543,11027293,11027293 0004,0415,0004,0114,0415,0415,0415,0415,0415,0096,0415 LC UBE3A EAPP 16713569,16713569 0397,0018 HT UBE3A NOMO2 21900206 0018 HT UBE3A YOD1 23827681 0415 LC UBE3A DKFZP666G145 22863883 0401 LC UBE3A JADE1 16713569,24722188,21900206,16713569 0397,0018,0018,0018 HT UBE3A TRIM65 21900206 0018 HT UBE3A AFTPH 21900206 0018 HT UBE3A LRSAM1 22863883 0401 LC UBE3A DKFZP686L23131 21900206 0018 HT UBE3A ATG9A 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT UBE3A SGK223 21900206 0018 HT UBE3A NELFCD 17131388,17131388,21988832,17131388 0415,0004,0018,0096 LC,HT UBE3A ASPM 21633703,21633703 0018,0004 LC UBE3A NPLOC4 22863883 0401 LC UBE3A ASAP3 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT UBE3A UFD1L 22939629 0401 LC UBE3A LPP 22863883 0401 LC UBE3A NEURL4 22645313,22645313 0004,0401 LC UBE3A BTF3L4 22863883 0401 LC UBE3A RNF2 20351251,20351251,26216987,20351251 0004,0415,0415,0096 LC UBE3A UNC45A 22939629 0401 LC UBE3A C11ORF49 21900206 0018 HT UBE3A RMI1 21900206 0018 HT UBE3A POLE4 21900206 0018 HT UBE3A PARVA 21900206 0018 HT UBE3A HIF1AN 22645313,22645313 0004,0401 LC UBE3A AHSP 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT UBE3A TBC1D14 21900206 0018 HT UBE3A METTL1 22863883 0401 LC UBE3A UBQLN2 10983987,10983987,10983987 0004,0018,0401 LC UBE3A IPO11 22863883 0401 LC UBE3A DBNL 22863883 0401 LC UBE3A HPCAL4 21900206 0018 HT UBE3A UBQLN1 10983987,10983987 0004,0018 LC UBE3A TCF19 21900206 0018 HT UBE3A LSM5 22939629 0401 LC UBE3A UCHL5 24743594 0415 LC UBE3A TNPO3 22939629 0401 LC UBE3A EID1 21900206 0018 HT UBE3A HEL-S-114 22939629 0401 LC UBE3A HEL2 21900206 0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q05086 B3KPL7 UBE3A B3KPL7 0.332 25416956 Q56P03 Q05086 EAPP UBE3A 0.376 16713569 Q5VVQ6 Q05086 YOD1 UBE3A 0.309 23827681 Q05086 O43396 UBE3A TXNL1 0.081 22939629 Q05086 O15126 UBE3A SCAMP1 0.376 16713569 Q05086 O15143 UBE3A ARPC1B 0.081 22863883 Q05086 P62191 UBE3A PSMC1 0.126 26496610 Q8IZT6 Q05086 ASPM UBE3A 0.569 21633703 Q9H4L4 Q05086 SENP3 UBE3A 0.126 26511642 Q9NQA5 Q05086 TRPV5 UBE3A 0.126 26186194 Q8TAT6 Q05086 NPLOC4 UBE3A 0.081 22863883 Q9NZJ4 Q05086 SACS UBE3A 0.309 23671107 Q9Y5L0 Q05086 TNPO3 UBE3A 0.081 22939629 Q9Y5K5 Q05086 UCHL5 UBE3A 0.126 26186194 Q05086 P08218 UBE3A CELA2B 0.126 26186194 Q6UWE0 Q05086 LRSAM1 UBE3A 0.081 22863883 Q05086 P0CG47 UBE3A UBB 0.183 25416956 Q7LC44 Q05086 ARC UBE3A 0.309 23671107 Q7Z3C6 Q05086 ATG9A UBE3A 0.454 25416956 Q6IE81 Q05086 JADE1 UBE3A 0.61 21900206,16713569,24722188 Q05086 P03372 UBE3A ESR1 0.396 16314411,22865929,9891052 Q05086 P04150 UBE3A NR3C1 0.033 9891052 Q05086 P04278 UBE3A SHBG 0.183 15862967 Q05086 P04629 UBE3A NTRK1 0.126 25921289 Q05086 O95714 UBE3A HERC2 0.623 25476789,21493713,22645313 Q05086 P06933 UBE3A E7 0.309 9467941 Q9Y4F3 Q05086 KIAA0430 UBE3A 0.236 unassigned1304 Q9NZD4 Q05086 AHSP UBE3A 0.454 25416956 Q9P0J0 Q05086 NDUFA13 UBE3A 0.454 21765936 Q05086 P04019 UBE3A E6 0.671 17023019,22810586 Q05086 P04083 UBE3A ANXA1 0.794 19204938 Q8TDY4 Q05086 ASAP3 UBE3A 0.454 25416956 Q96C32 Q05086 UBC UBE3A 0.236 unassigned1304 Q96CS3 Q05086 FAF2 UBE3A 0.236 18775313 Q05086 P06462 UBE3A E6 0.236 22810586 Q92731 Q05086 ESR2 UBE3A 0.376 17962381,25408199 Q05086 P06931 UBE3A E6 0.523 9467941,7624774 Q99JI4 Q05086 PSMD6 UBE3A 0.236 26496610 Q05086 P06239 UBE3A LCK 0.523 10449731 Q05086 P07602 UBE3A PSAP 0.332 21900206 Q05086 P06463 UBE3A E6 0.671 7624774,22810586,16493710 Q05086 P0CG48 UBE3A UBC 0.523 23439649,9575161 Q05086 P55854 UBE3A SUMO3 0.332 21900206 Q05086 P53804 UBE3A TTC3 0.332 21900206 Q05086 P63104 UBE3A YWHAZ 0.332 21900206 Q05086 Q03701 UBE3A CEBPZ 0.332 21900206 Q05086 P62158 UBE3A CALM3 0.396 16051665,26506232 Q05086 P62258 UBE3A YWHAE 0.332 21900206 Q92966 Q05086 SNAPC3 UBE3A 0.236 unassigned1304 Q3BBW0 Q05086 NBPF9 UBE3A 0.236 unassigned1304 Q9NWT6 Q05086 HIF1AN UBE3A 0.309 22645313 Q16611 Q05086 BAK1 UBE3A 0.454 9881696 Q5JPE7 Q05086 NOMO2 UBE3A 0.332 21900206 Q86YV5 Q05086 SGK223 UBE3A 0.332 21900206 Q9NVD7 Q05086 PARVA UBE3A 0.332 21900206 Q96JN8 Q05086 NEURL4 UBE3A 0.309 22645313 Q9P2M4 Q05086 TBC1D14 UBE3A 0.332 21900206 Q9Y6B2 Q05086 EID1 UBE3A 0.332 21900206 Q05086 Q04323 UBE3A UBXN1 0.236 18775313 Q05086 O14599 UBE3A BPY2C 0.454 12207887 Q05086 P33993 UBE3A MCM7 0.454 9852095 Q05086 P51668 UBE3A UBE2D1 0.925 15001357,19240029,17426036,9450543,8576257,10066826 Q05086 O55234 UBE3A PSMB5 0.236 26496610 Q05086 P60896 UBE3A SHFM1 0.236 24811749 Q77E16 Q05086 E6 UBE3A 0.507 17023019,17166906 Q05086 P54725 UBE3A RAD23A 0.905 19013454,23671107,10373495,17426036,26216987,9153201 Q05086 P10276 UBE3A RARA 0.309 16713569,9891052 Q05086 P51965 UBE3A UBE2E1 0.671 8576257,9153201 Q5U5U6 Q05086 UBB UBE3A 0.332 25416956 Q9UHD9 Q05086 UBQLN2 UBE3A 0.523 10983987 Q05086 P03126 UBE3A E6 0.876 11027293,26915086,9467941,26789255,7624774,22810586 Q05086 P17735 UBE3A TAT 0.772 25416956,unassigned1304,24722188,25910212 Q05086 P68036 UBE3A UBE2L3 1 11027293,17603074,26216987,9153201,17433363,20589759,10558980,10373495,19204938,19364824,11431533,17131388,19899154,8576257,9990509 Q05086 P04637 UBE3A TP53 0.999 8380895,11027293,1661671,9450543,26789255,23040663,16493710,7724550,7708685,9688277,15001357,12620801,19364824,8090726,17131388 Q05086 Q05086 UBE3A UBE3A 0.987 17426036,26216987,26506232,24273172,22496338,9575161,15331633,9688277,21033666,12620801 Q05086 P36799 UBE3A E6 0.21 15890204 Q05086 P29590 UBE3A PML 0.454 19325566 Q93052 Q05086 LPP UBE3A 0.081 22863883 Q8WYA1 Q05086 ARNTL2 UBE3A 0.21 25660546 Q96K17 Q05086 BTF3L4 UBE3A 0.081 22863883 Q05086 P38398 UBE3A BRCA1 0.309 12890688 Q99728 Q05086 BARD1 UBE3A 0.309 12890688 Q99496 Q05086 RNF2 UBE3A 0.74 20351251,26216987 Q99583 Q05086 MNT UBE3A 0.569 26506232 Q9UBP6 Q05086 METTL1 UBE3A 0.081 22863883 Q9UJU6 Q05086 DBNL UBE3A 0.081 22863883 Q9UM19 Q05086 HPCAL4 UBE3A 0.332 21900206 Q9UMX0 Q05086 UBQLN1 UBE3A 0.454 10983987 Q05086 P34932 UBE3A HSPA4 0.623 23040663,19233847 Q05086 P46527 UBE3A CDKN1B 0.454 19591933 Q05086 P69905 UBE3A HBA2 0.332 21900206 Q05086 P62837 UBE3A UBE2D2 0.891 19325566,9182527,26216987,9990509,7724550 Q13838 Q05086 DDX39B UBE3A 0.081 22939629 Q14160 Q05086 SCRIB UBE3A 0.78 16482544,11027293 Q05086 P43355 UBE3A MAGEA1 0.126 26186194 Q05086 P49815 UBE3A TSC2 0.623 15175323,18298802 Q05086 Q01064 UBE3A PDE1B 0.332 21900206 Q15393 Q05086 SF3B3 UBE3A 0.081 22939629 Q05086 P51451 UBE3A BLK 0.523 10449731 Q13404 Q05086 UBE2V1 UBE3A 0.033 25260751 Q13242 Q05086 SRSF9 UBE3A 0.081 22939629 Q05086 P17386 UBE3A E6 0.309 7624774 Q05086 Q03405 UBE3A PLAUR 0.126 26186194 Q05086 O00487 UBE3A PSMD14 0.126 26496610 Q06830 Q05086 PRDX1 UBE3A 0.623 20589759 Q12789 Q05086 GTF3C1 UBE3A 0.309 26506232 Q32P28 Q05086 LEPRE1 UBE3A 0.081 22863883 Q16659 Q05086 MAPK6 UBE3A 0.396 26972000,22645313 Q08378 Q05086 GOLGA3 UBE3A 0.126 16051665 Q05086 P54727 UBE3A RAD23B 0.523 10373495 Q05086 P00995 UBE3A SPINK1 0.309 26506232 Q05086 P00441 UBE3A SOD1 0.309 23040663 Q05086 A1L4G7 UBE3A TAT {ECO:0000313|EMBL:AAI30535.1} 0.332 25416956 Q05086 O94989 UBE3A ARHGEF15 0.21 21029865 Q05086 O14933 UBE3A UBE2L6 0.523 9153201,17433363 Q05086 O00327 UBE3A ARNTL 0.507 24728990,25660546 Q05086 O15116 UBE3A LSM1 0.081 22863883 Q05086 O75592 UBE3A MYCBP2 0.126 16051665 Q05086 O43242 UBE3A PSMD3 0.126 16051665 Q05086 P13569 UBE3A CFTR 0.332 17110338,19233847 Q05086 P08238 UBE3A HSP90AB1 0.309 26506232 Q05086 P04259 UBE3A KRT6B 0.309 26506232 Q05086 P05067 UBE3A APP 0.183 21832049 Q05086 P04264 UBE3A KRT1 0.309 26506232 Q05086 P06401 UBE3A PGR 0.539 9891052 Q05086 P35527 UBE3A KRT9 0.309 26506232 Q05086 P07355 UBE3A ANXA2 0.126 16051665 Q05086 P12956 UBE3A XRCC6 0.126 16051665 Q05086 P11142 UBE3A HSPA8 0.376 19233847 Q05086 P08729 UBE3A KRT7 0.309 26506232 Q05086 P11021 UBE3A HSPA5 0.309 26506232 Q05086 P10275 UBE3A AR 0.236 16254014,9891052 Q05086 P13647 UBE3A KRT5 0.309 26506232 Q05086 P30101 UBE3A PDIA3 0.309 26506232 Q05086 P14136 UBE3A GFAP 0.309 26506232 Q05086 P26045 UBE3A PTPN3 0.21 17166906 Q05086 P15735 UBE3A PHKG2 0.126 16051665 Q05086 P27797 UBE3A CALR 0.309 26506232 Q05086 P55036 UBE3A PSMD4 0.712 19240029,22350919,25633294,22645313 Q05086 P60709 UBE3A ACTB 0.309 26506232 Q05086 P50222 UBE3A MEOX2 0.183 24722188 Q05086 P35579 UBE3A MYH9 0.126 16051665 Q05086 P43361 UBE3A MAGEA8 0.183 24722188 Q05086 P37837 UBE3A TALDO1 0.309 26506232 Q05086 P46019 UBE3A PHKA2 0.126 16051665 Q05086 P49715 UBE3A CEBPA 0.569 23598402 Q05086 Q04637 UBE3A EIF4G1 0.332 21900206 Q05086 P52566 UBE3A ARHGDIB 0.309 26506232 Q05086 P54578 UBE3A USP14 0.081 22939629 Q05086 P61158 UBE3A ACTR3 0.309 26506232 Q05086 P61077 UBE3A UBE2D3 0.523 9990509,11486026 Q05086 P62736 UBE3A ACTA2 0.309 26506232 Q05086 P62244 UBE3A RPS15A 0.309 26506232 Q05086 P68133 UBE3A ACTA1 0.126 16051665 Q05086 Q01658 UBE3A DR1 0.081 22863883 Q05086 Q00987 UBE3A MDM2 0.309 11486026 Q05086 Q00613 UBE3A HSF1 0.081 22863883 Q2WGJ6 Q05086 KLHL38 UBE3A 0.454 25416956 Q12959 Q05086 DLG1 UBE3A 0.309 16482544 Q16816 Q05086 PHKG1 UBE3A 0.126 16051665 Q15084 Q05086 PDIA6 UBE3A 0.309 26506232 Q92890 Q05086 UFD1L UBE3A 0.081 22939629 Q562R1 Q05086 ACTBL2 UBE3A 0.309 26506232 Q6ULP2 Q05086 AFTPH UBE3A 0.332 21900206 Q6PJ69 Q05086 TRIM65 UBE3A 0.332 21900206 Q8TC05 Q05086 MDM1 UBE3A 0.309 26506232 Q8IXH7 Q05086 NELFCD UBE3A 0.748 17131388,21988832 Q9H6J7 Q05086 C11ORF49 UBE3A 0.332 21900206 Q9H3U1 Q05086 UNC45A UBE3A 0.081 22939629 Q93100 Q05086 PHKB UBE3A 0.126 16051665 Q9H6R7 Q05086 C2ORF44 UBE3A 0.126 16051665 Q9NR33 Q05086 POLE4 UBE3A 0.332 21900206 Q9H9A7 Q05086 RMI1 UBE3A 0.332 21900206 Q9UI26 Q05086 IPO11 UBE3A 0.081 22863883 Q9Y242 Q05086 TCF19 UBE3A 0.332 21900206 Q9Y6Q9 Q05086 NCOA3 UBE3A 0.376 16951183

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 ARNTL UBE3A MI:0045 experimental interaction detection MI:0461 interaction database PSMD14 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database BPY2 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database UBE2L6 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database SCAMP1 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database SMAD9 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database UBD UBE3A MI:0045 experimental interaction detection MI:0461 interaction database PSMD3 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database MYCBP2 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database ARHGEF15 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database HERC2 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database SOD1 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database SPINK1 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database ESR1 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database ANXA1 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database KRT6B UBE3A MI:0045 experimental interaction detection MI:0461 interaction database KRT1 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database SHBG UBE3A MI:0045 experimental interaction detection MI:0461 interaction database NTRK1 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database TP53 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database APP UBE3A MI:0045 experimental interaction detection MI:0461 interaction database LCK UBE3A MI:0045 experimental interaction detection MI:0461 interaction database PGR UBE3A MI:0045 experimental interaction detection MI:0461 interaction database ANXA2 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database PSAP UBE3A MI:0045 experimental interaction detection MI:0461 interaction database CELA2B UBE3A MI:0045 experimental interaction detection MI:0461 interaction database HSP90AB1 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database KRT7 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database UBB UBE3A MI:0045 experimental interaction detection MI:0461 interaction database UBC UBE3A MI:0045 experimental interaction detection MI:0461 interaction database AR UBE3A MI:0045 experimental interaction detection MI:0461 interaction database RARA UBE3A MI:0045 experimental interaction detection MI:0461 interaction database HSPA5 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database HSPA8 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database XRCC6 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database CFTR UBE3A MI:0045 experimental interaction detection MI:0461 interaction database KRT5 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database GFAP UBE3A MI:0045 experimental interaction detection MI:0461 interaction database PHKG2 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database TAT UBE3A MI:0045 experimental interaction detection MI:0461 interaction database PSMC3 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database PTPN3 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database CALR UBE3A MI:0045 experimental interaction detection MI:0461 interaction database PSMB5 UBE3A MI:0362 inference MI:0461 interaction database PML UBE3A MI:0045 experimental interaction detection MI:0461 interaction database PDIA3 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database MCM7 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database HSPA4 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database KRT9 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database MYH9 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database TALDO1 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database BRCA1 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database MAGEA1 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database MAGEA8 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database PHKA2 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database CDKN1B UBE3A MI:0045 experimental interaction detection MI:0461 interaction database CEBPA UBE3A MI:0045 experimental interaction detection MI:0461 interaction database TSC2 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database MEOX2 UBE3A MI:0045 experimental interaction detection MI:0461 interaction database BLK UBE3A 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