Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 2 27550967 rs1049817 A G rs1049817 3.10E-06 PRAVASTATIN|CHOLESTEROL|ATORVASTATIN|SIMVASTATIN PYRROLES|LIPIDS|HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS|HEPTANOIC ACIDS Response to statin therapy HPOID:0001677 DOID:3393|DOID:423|DOID:1936 C cds-synon GWASdb_drug 2 27550967 rs1049817 A G rs1049817 1.20E-07 URIC ACID NA Urate levels HPOID:0000079 DOID:13189 C cds-synon GWASdb_drug 2 27550967 rs1049817 A G rs1049817 1.05E-16 URIC ACID GLUCOSE|INHIBINS Urate levels HPOID:0000079 DOID:13189 C cds-synon GWASdb_drug 2 27556721 rs3739095 G A rs3739095 2.90E-07 PRAVASTATIN|CHOLESTEROL|ATORVASTATIN|SIMVASTATIN PYRROLES|LIPIDS|HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS|HEPTANOIC ACIDS Response to statin therapy HPOID:0001677 DOID:3393|DOID:423|DOID:1936 A intron GWASdb_drug 2 27556721 rs3739095 G A rs3739095 1.40E-10 URIC ACID NA Urate levels HPOID:0000079 DOID:13189 A intron GWASdb_drug 2 27556721 rs3739095 G A rs3739095 4.54E-21 URIC ACID GLUCOSE|INHIBINS Urate levels HPOID:0000079 DOID:13189 A intron GWASdb_drug 2 27558252 rs11684134 A G rs11684134 2.10E-06 PRAVASTATIN|CHOLESTEROL|ATORVASTATIN|SIMVASTATIN PYRROLES|LIPIDS|HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS|HEPTANOIC ACIDS Response to statin therapy HPOID:0001677 DOID:3393|DOID:423|DOID:1936 A intron GWASdb_drug 2 27558252 rs11684134 A G rs11684134 7.10E-09 URIC ACID NA Urate levels HPOID:0000079 DOID:13189 A intron GWASdb_drug 2 27558252 rs11684134 A G rs11684134 5.51E-18 URIC ACID GLUCOSE|INHIBINS Urate levels HPOID:0000079 DOID:13189 A intron GWASdb_drug 2 27566520 rs11689803 T A rs11689803 8.50E-06 PRAVASTATIN|CHOLESTEROL|ATORVASTATIN|SIMVASTATIN PYRROLES|LIPIDS|HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS|HEPTANOIC ACIDS Response to statin therapy HPOID:0001677 DOID:3393|DOID:423|DOID:1936 T intron GWASdb_drug 2 27566520 rs11689803 T A rs11689803 4.87E-13 URIC ACID GLUCOSE|INHIBINS Urate levels HPOID:0000079 DOID:13189 T intron GWASdb_drug 2 27567407 rs6743819 G T rs6743819 3.60E-06 PRAVASTATIN|CHOLESTEROL|ATORVASTATIN|SIMVASTATIN PYRROLES|LIPIDS|HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS|HEPTANOIC ACIDS Response to statin therapy HPOID:0001677 DOID:3393|DOID:423|DOID:1936 T intron GWASdb_drug 2 27567407 rs6743819 G T rs6743819 1.40E-07 URIC ACID NA Urate levels HPOID:0000079 DOID:13189 T intron GWASdb_drug 2 27567407 rs6743819 G T rs6743819 5.50E-17 URIC ACID GLUCOSE|INHIBINS Urate levels HPOID:0000079 DOID:13189 T intron GWASdb_drug 2 27568565 rs10205219 T C rs10205219 3.70E-06 PRAVASTATIN|CHOLESTEROL|ATORVASTATIN|SIMVASTATIN PYRROLES|LIPIDS|HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS|HEPTANOIC ACIDS Response to statin therapy HPOID:0001677 DOID:3393|DOID:423|DOID:1936 C intron GWASdb_drug 2 27568565 rs10205219 T C rs10205219 1.40E-07 URIC ACID NA Urate levels HPOID:0000079 DOID:13189 C intron GWASdb_drug 2 27568565 rs10205219 T C rs10205219 5.45E-17 URIC ACID GLUCOSE|INHIBINS Urate levels HPOID:0000079 DOID:13189 C intron GWASdb_drug 2 27574953 rs4665969 T C rs4665969 3.60E-06 PRAVASTATIN|CHOLESTEROL|ATORVASTATIN|SIMVASTATIN PYRROLES|LIPIDS|HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS|HEPTANOIC ACIDS Response to statin therapy HPOID:0001677 DOID:3393|DOID:423|DOID:1936 T intron GWASdb_drug 2 27574953 rs4665969 T C rs4665969 1.30E-07 URIC ACID NA Urate levels HPOID:0000079 DOID:13189 T intron GWASdb_drug 2 27574953 rs4665969 T C rs4665969 1.15E-16 URIC ACID GLUCOSE|INHIBINS Urate levels HPOID:0000079 DOID:13189 T intron GWASdb_drug 2 27579231 rs6760828 T C rs6760828 3.70E-06 PRAVASTATIN|CHOLESTEROL|ATORVASTATIN|SIMVASTATIN PYRROLES|LIPIDS|HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS|HEPTANOIC ACIDS Response to statin therapy HPOID:0001677 DOID:3393|DOID:423|DOID:1936 C intron GWASdb_drug 2 27579231 rs6760828 T C rs6760828 1.20E-07 URIC ACID NA Urate levels HPOID:0000079 DOID:13189 C intron GWASdb_drug 2 27579231 rs6760828 T C rs6760828 9.10E-17 URIC ACID GLUCOSE|INHIBINS Urate levels HPOID:0000079 DOID:13189 C intron GWASdb_drug 2 27550967 rs1049817 A G rs1049817 1.45E-06 Lipid levels HPOID:0003119 DOID:3146|DOID:1287|DOID:9970 C cds-synon GWASdb_trait 2 27550967 rs1049817 A G rs1049817 3.10E-06 Response to statin therapy HPOID:0001677 DOID:3393|DOID:423|DOID:1936 C cds-synon GWASdb_trait 2 27550967 rs1049817 A G rs1049817 1.20E-07 Urate levels HPOID:0000079 DOID:13189 C cds-synon GWASdb_trait 2 27550967 rs1049817 A G rs1049817 9.70E-30 Triglycerides HPOID:0003119 DOID:3393|DOID:3146|DOID:2349 C cds-synon GWASdb_trait 2 27550967 rs1049817 A G rs1049817 1.05E-16 Urate levels HPOID:0000079 DOID:13189 C cds-synon GWASdb_trait 2 27556721 rs3739095 G A rs3739095 2.90E-07 Response to statin therapy HPOID:0001677 DOID:3393|DOID:423|DOID:1936 A intron GWASdb_trait 2 27556721 rs3739095 G A rs3739095 1.40E-10 Urate levels HPOID:0000079 DOID:13189 A intron GWASdb_trait 2 27556721 rs3739095 G A rs3739095 4.54E-21 Urate levels HPOID:0000079 DOID:13189 A intron GWASdb_trait 2 27558252 rs11684134 A G rs11684134 2.10E-06 Response to statin therapy HPOID:0001677 DOID:3393|DOID:423|DOID:1936 A intron GWASdb_trait 2 27558252 rs11684134 A G rs11684134 7.10E-09 Urate levels HPOID:0000079 DOID:13189 A intron GWASdb_trait 2 27558252 rs11684134 A G rs11684134 5.51E-18 Urate levels HPOID:0000079 DOID:13189 A intron GWASdb_trait 2 27566520 rs11689803 T A rs11689803 8.50E-06 Response to statin therapy HPOID:0001677 DOID:3393|DOID:423|DOID:1936 T intron GWASdb_trait 2 27566520 rs11689803 T A rs11689803 4.87E-13 Urate levels HPOID:0000079 DOID:13189 T intron GWASdb_trait 2 27567407 rs6743819 G T rs6743819 3.60E-06 Response to statin therapy HPOID:0001677 DOID:3393|DOID:423|DOID:1936 T intron GWASdb_trait 2 27567407 rs6743819 G T rs6743819 1.40E-07 Urate levels HPOID:0000079 DOID:13189 T intron GWASdb_trait 2 27567407 rs6743819 G T rs6743819 5.50E-17 Urate levels HPOID:0000079 DOID:13189 T intron GWASdb_trait 2 27568565 rs10205219 T C rs10205219 3.70E-06 Response to statin therapy HPOID:0001677 DOID:3393|DOID:423|DOID:1936 C intron GWASdb_trait 2 27568565 rs10205219 T C rs10205219 1.40E-07 Urate levels HPOID:0000079 DOID:13189 C intron GWASdb_trait 2 27568565 rs10205219 T C rs10205219 5.45E-17 Urate levels HPOID:0000079 DOID:13189 C intron GWASdb_trait 2 27574953 rs4665969 T C rs4665969 3.60E-06 Response to statin therapy HPOID:0001677 DOID:3393|DOID:423|DOID:1936 T intron GWASdb_trait 2 27574953 rs4665969 T C rs4665969 1.30E-07 Urate levels HPOID:0000079 DOID:13189 T intron GWASdb_trait 2 27574953 rs4665969 T C rs4665969 1.15E-16 Urate levels HPOID:0000079 DOID:13189 T intron GWASdb_trait 2 27579231 rs6760828 T C rs6760828 3.70E-06 Response to statin therapy HPOID:0001677 DOID:3393|DOID:423|DOID:1936 C intron GWASdb_trait 2 27579231 rs6760828 T C rs6760828 1.20E-07 Urate levels HPOID:0000079 DOID:13189 C intron GWASdb_trait 2 27579231 rs6760828 T C rs6760828 9.10E-17 Urate levels HPOID:0000079 DOID:13189 C intron GWASdb_trait

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000115207.13 GTF3C2 604883