PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus SNAP29 TRIM62 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G CNTROB TRIM62 26638075 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G SFN TRIM62 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G UBE2D2 TRIM62 23402750 innatedb exp G G G G G G G G G G G G G G G G G G G G G G G G G SKIL TRIM62 15231748 hprd,biogrid,i2d,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G TRIM62 CCDC94 26186194 biogrid exp G G G G G G G G G G G G G G G SMAD2 TRIM62 15231748 hprd,biogrid,i2d,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G SMAD3 TRIM62 23838884 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G RNF103 TRIM62 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G TRIM41 TRIM62 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G RFPL4A TRIM62 23023127 pred TRIM62 TRIM35 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9BVG3 P12757-5 two hybrid 15231748 direct interaction X 2 Q9BVG3 affinity chromatography technology 23838884 physical association X 2 Q9BVG3 affinity chromatography technology 23838884 physical association X 2 Q9BVG3 pull down 23838884 direct interaction X 2 Q9BVG3 imaging technique 23838884 colocalization X 2 P0CG48 Q9BVG3 affinity chromatography technology 21963094 physical association X 2 P0CG48 Q9BVG3 affinity chromatography technology 21906983 physical association X 2 Q9BVG3 Q15796-2 two hybrid 15231748 direct interaction X 2 Q9BVG3 P12757-3 two hybrid 15231748 - X 2 Q9BVG3 Q15796-2 two hybrid 15231748 - X 2 Q9BVG3 Q15796-2 two hybrid 15231748 - X 2 Q9BVG3 P12757-3 two hybrid 15231748 - X 2 Q9BVG3 P29991 two hybrid 21911577 physical association X 2 Q9BVG3 Q99IB8 two hybrid 24136289 physical association X 2 Q15796 Q9BVG3 two hybrid 15231748 physical association X 2 P12757 Q9BVG3 two hybrid 15231748 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality SNAP29 TRIM62 26186194 0004 HT SFN TRIM62 26186194 0004 HT CNTROB TRIM62 26638075,26638075 1314,1313 HT TRIM62 CCDC94 26186194 0004 HT SNAP29 TRIM62 26186194 0004 HT SFN TRIM62 26186194 0004 HT CNTROB TRIM62 26638075,26638075 1314,1313 HT TRIM62 CCDC94 26186194 0004 HT SKIL TRIM62 15231748 0018 HT SMAD2 TRIM62 15231748 0018 HT TRIM62 CARD9 26488816,26488816,26488816,26488816,26488816 0096,0415,0428,0004,0055 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9BVG3 Q8N137 TRIM62 CNTROB 0.126 26638075 Q9BVG3 O95721 TRIM62 SNAP29 0.126 26186194 Q9P0N9 Q9BVG3 TBC1D7 TRIM62 0.236 unassigned1304 Q9NQT4 Q9BVG3 EXOSC5 TRIM62 0.236 unassigned1304 Q9Y2X8 Q9BVG3 UBE2D4 TRIM62 0.236 unassigned1304 Q9BVG3 Q969T4 TRIM62 UBE2E3 0.236 unassigned1304 Q9BVG3 P12757 TRIM62 SKIL 0.332 15231748 Q9BVG3 O94888 TRIM62 UBXN7 0.236 unassigned1304 Q9BVG3 Q8TDD2 TRIM62 SP7 0.236 unassigned1304 Q9BVG3 Q6NYC8 TRIM62 PPP1R18 0.236 unassigned1304 Q9NVQ4 Q9BVG3 FAIM TRIM62 0.236 unassigned1304 Q9BVG3 Q96JC9 TRIM62 EAF1 0.236 unassigned1304 Q9BVG3 Q9BVG3 TRIM62 TRIM62 0.286 unassigned1304 Q9BVG3 Q15796 TRIM62 SMAD2 0.332 15231748 Q9BVG3 Q68CQ4 TRIM62 DIEXF 0.236 unassigned1304 Q9BVG3 P35754 TRIM62 GLRX 0.236 unassigned1304 Q9BVG3 P51668 TRIM62 UBE2D1 0.236 unassigned1304 Q9BVG3 O95208 TRIM62 EPN2 0.236 unassigned1304 Q9BVG3 O14933 TRIM62 UBE2L6 0.236 unassigned1304 Q9BVG3 P61077 TRIM62 UBE2D3 0.236 unassigned1304 Q9BVG3 P29991 TRIM62 P29991 0.183 21911577 Q9BVG3 P31947 TRIM62 SFN 0.126 26186194 Q9BVG3 Q99IB8 TRIM62 Q99IB8 0.183 24136289 Q9BVG3 P62837 TRIM62 UBE2D2 0.309 26488816 Q9H257 Q9BVG3 CARD9 TRIM62 0.772 26488816 Q9BW85 Q9BVG3 CCDC94 TRIM62 0.126 26186194 Q9BVG3 P84022 TRIM62 SMAD3 0.623 23838884

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 SNAP29 TRIM62 MI:0045 experimental interaction detection MI:0461 interaction database UBC TRIM62 MI:0045 experimental interaction detection MI:0461 interaction database SKIL TRIM62 MI:0045 experimental interaction detection MI:0461 interaction database SFN TRIM62 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D2 TRIM62 MI:0045 experimental interaction detection MI:0461 interaction database SMAD3 TRIM62 MI:0045 experimental interaction detection MI:0461 interaction database SMAD2 TRIM62 MI:0045 experimental interaction detection MI:0461 interaction database CNTROB TRIM62 MI:0045 experimental interaction detection MI:0461 interaction database TRIM62 CCDC94 MI:0045 experimental interaction detection MI:0461 interaction database TRIM62 CARD9 MI:0045 experimental interaction detection MI:0461 interaction database