Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 1 202866331 rs10920519 A C rs10920519 8.84E-04 Obesity (extreme) HPOID:0001513 DOID:9970 A intron GWASdb_trait 1 202871238 rs7542125 T C rs7542125 8.79E-04 Obesity (extreme) HPOID:0001513 DOID:9970 T intron GWASdb_trait 1 202884063 rs10800877 C T rs10800877 4.81E-04 Smoking initiation HPOID:0000707 DOID:0050742 C intron GWASdb_trait 1 202892917 rs10800880 T C rs10800880 9.61E-04 Obesity (extreme) HPOID:0001513 DOID:9970 T intron GWASdb_trait

Disease associated variation - GWAS Central Study Name Source Marker Accession Chromosome Marker Start Marker Stop Alleles Gene Section P-value -log(p-value) GWAS of prostate cancer rs8179338 1 202882303 202882303 intronic 0.114031 0.942977067095478 GWAS of prostate cancer rs9919219 1 202877397 202877397 intronic 0.09787 1.00935041168115 GWAS of prostate cancer rs4950887 1 202870330 202870330 intronic 0.087244 1.0592644309188401 GWAS of prostate cancer rs4950889 1 202874786 202874786 intronic 0.067193 1.17267596831107

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000117153.15 KLHL12 614522