PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus UBXN1 KLHL12 18775313 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G VEGFB KLHL12 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 KLHL3 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CPSF6 KLHL12 16189514 hprd,biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ATXN1 KLHL12 16713569 hprd,biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 RIT1 183031015,18303015 hprd,biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G EZH2 KLHL12 24457600 innatedb,biogrid exp G G G G G G G G G G G G NEDD8 KLHL12 21145461 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SDCBP KLHL12 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DRD4 KLHL12 20100572,18303015 hprd,biogrid exp KLHL12 COPS6 21145461 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 C1QTNF2 25416956 biogrid,intact exp G G G G G G DVL2 KLHL12 20007894 i2d exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 TBC1D10C 25416956 biogrid,intact exp G G G G G G G G G G G G G KLHL12 FGD2 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 MED28 16189514 hprd,biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 VTA1 16189514 hprd,biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 SNX20 25416956,16189514 hprd,biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 DCUN1D1 21145461 biogrid exp G G G G G G G G G G G G G G G G KLHL12 COPS5 21145461 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 PEF1 25416956,16189514 innatedb,biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G FLNA KLHL12 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 MAP1LC3A 20562859 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 CEP170P1 26496610 intact exp KLHL12 TTBK2 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 RPP25L 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 CARD10 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 CCBE1 25416956 biogrid,intact exp G G G G G G KLHL12 DROSHA 24778252 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 SYNE4 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G NDC80 KLHL12 16189514 hprd,biogrid,mint,intact exp G G G G G BAG6 KLHL12 25416956,16189514 hprd,biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G INMT KLHL12 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G G G KLHL12 LNX1 16189514 hprd,biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G PDGFRB KLHL12 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 MRPL10 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 PRR13 25416956,16189514 hprd,biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 ZBP1 25416956 biogrid,intact exp G G KLHL12 KLHL12 25416956,16189514 hprd,biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2I KLHL12 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G COL8A1 KLHL12 16189514 hprd,biogrid,intact exp G G G G G G G G G G G G G G G G KLHL12 GLYCTK 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G MPP1 KLHL12 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 WDYHV1 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 MED12 26496610 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 MAP1LC3B 20562859 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBC KLHL12 16196087 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL2 KLHL12 15383316,16189514,21516116 hprd,biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DGCR6 KLHL12 24722188 biogrid exp KLHL12 TAOK2 24722188 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ARAF KLHL12 16189514 hprd,biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CUL3 KLHL12 25416956,19295130,16547521,17543862,21145461,18303015, 25402006, 21836163 innatedb,hprd,biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 DVL3 16189514,16547521,20007894, 25402006 hprd,biogrid,i2d,mint,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 CAND1 21145461, 25402006 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN7 KLHL12 18775313, 25402006 biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 IPP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 KCTD11 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 BRWD1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G PRPF3 KLHL12 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G DVL1 KLHL12 25402006, 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 KLHL26 23023127 pred G G G G G G G G G G G G G G G G G G G G KLHL12 ALG2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 BTBD6 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 PRICKLE1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 ABTB2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 FAF1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CUL2 KLHL12 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PDCD6 KLHL12 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 KLHL15 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 BTRC 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DAZAP2 KLHL12 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 LRRFIP2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CSNK1D KLHL12 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G H2AFX KLHL12 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 KLHDC2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 GABARAPL1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NF2 KLHL12 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 FBXW7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G CUL1 KLHL12 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 KLHL4 23023127 pred G G G G G G G CUL4B KLHL12 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 WDR26 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 KLHL1 23023127 pred G G G KLHL12 NKD1 25402006 pred G G G G G G G G G G RLF KLHL12 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 ZBTB33 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLHL12 KLHL22 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q86VP6 Q53G59 affinity chromatography technology 21145461 physical association X 2 P0CG48 Q53G59 affinity chromatography technology 21963094 physical association X 2 P0CG48 Q53G59 affinity chromatography technology 18303015 physical association X 2 P0CG48 Q53G59 affinity chromatography technology 16196087 physical association X 2 P0CG48 Q53G59 affinity chromatography technology 21139048 physical association X 2 P0CG48 Q53G59 affinity chromatography technology 21906983 physical association X 2 A0A024R539 Q53G59 affinity chromatography technology 18775313 physical association X 2 Q53G59 A0A024R178 two hybrid 16189514 direct interaction X 2 Q53G59 A0A024R475 affinity chromatography technology 17543862 physical association X 2 Q53G59 A0A024R475 affinity chromatography technology 21145461 physical association X 2 Q53G59 A0A024R7W9 affinity chromatography technology 21145461 physical association X 2 Q53G59 Q7L5N1 affinity chromatography technology 21145461 physical association X 2 Q53G59 O95198-2 affinity chromatography technology 15383316 physical association X 2 Q53G59 Q96FF1 two hybrid 16713569 direct interaction X 2 Q53G59 Q96FF1 affinity chromatography technology 16713569 physical association X 2 Q53G59 A0A024R475 affinity chromatography technology 19295130 physical association X 2 Q53G59 Q9UL54-4 two hybrid 24722188 direct interaction X 2 Q53G59 Q60FE5 two hybrid 25416956 direct interaction X 2 Q53G59 Q00013-3 two hybrid 25416956 direct interaction X 2 Q53G59 P09619 two hybrid 25416956 direct interaction X 2 Q53G59 P63279 two hybrid 25416956 direct interaction X 2 Q53G59 A0A024R475 two hybrid 25416956 direct interaction X 2 Q53G59 O95050-2 two hybrid 25416956 direct interaction X 2 Q53G59 A0A024RB45 two hybrid 25416956 direct interaction X 2 Q53G59 Q96HA8 two hybrid 25416956 direct interaction X 2 Q53G59 Q53G59 two hybrid 25416956 direct interaction X 2 Q53G59 Q7Z7H8-2 two hybrid 25416956 direct interaction X 2 Q53G59 Q8IVS8-4 two hybrid 25416956 direct interaction X 2 Q53G59 Q8N5L8 two hybrid 25416956 direct interaction X 2 Q53G59 Q6IQ55 two hybrid 25416956 direct interaction X 2 Q53G59 Q6UXH8 two hybrid 25416956 direct interaction X 2 Q53G59 Q8N205 two hybrid 25416956 direct interaction X 2 Q53G59 affinity chromatography technology 24457600 physical association X 2 Q53G59 A0A024RAS5 affinity chromatography technology 18303015 physical association X 2 Q53G59 A0A024R475 affinity chromatography technology 18303015 physical association X 2 Q53G59 A0A024R475 affinity chromatography technology 18303015 physical association X 2 Q53G59 A0A024R475 affinity chromatography technology 16547521 physical association X 2 Q53G59 affinity chromatography technology 20100572 physical association X 2 Q53G59 enzymatic study 20100572 direct interaction X 2 Q53G59 O94888 affinity chromatography technology 18775313 physical association X 2 Q53G59 A0A024RB45 two hybrid 16189514 direct interaction X 2 Q53G59 Q53G59 two hybrid 16189514 direct interaction X 2 Q53G59 O95198-2 two hybrid 16189514 direct interaction X 2 Q9H204 Q53G59 two hybrid 16189514 direct interaction X 2 P27658 Q53G59 two hybrid 16189514 direct interaction X 2 Q53G59 Q96GG9 affinity chromatography technology 21145461 physical association X 2 Q53G59 Q15843 affinity chromatography technology 21145461 physical association X 2 Q53G59 affinity chromatography technology 24778252 physical association X 2 Q53G59 Q14129 two hybrid 24722188 direct interaction X 2 Q53G59 G5EA09 two hybrid 25416956 direct interaction X 2 Q53G59 P49765-2 two hybrid 25416956 direct interaction X 2 Q53G59 two hybrid 25416956 direct interaction X 2 Q53G59 Q9BWT7 two hybrid 25416956 direct interaction X 2 Q53G59 Q9H171-2 two hybrid 25416956 direct interaction X 2 Q53G59 two hybrid 25416956 direct interaction X 2 Q53G59 Q7Z614 two hybrid 25416956 direct interaction X 2 Q53G59 Q7Z6J4 two hybrid 25416956 direct interaction X 2 Q53G59 Q8IV04 two hybrid 25416956 direct interaction X 2 Q53G59 Q9UBV8 two hybrid 25416956 direct interaction X 2 Q53G59 Q92963 affinity chromatography technology 18303015 physical association X 2 Q53G59 Q92963 affinity chromatography technology 18303015 physical association X 2 Q53G59 Q92997 affinity chromatography technology 16547521 physical association X 2 Q53G59 Q7Z614 two hybrid 16189514 direct interaction X 2 Q53G59 two hybrid 16189514 direct interaction X 2 Q53G59 Q8TBB1 two hybrid 16189514 direct interaction X 2 Q53G59 Q92997 two hybrid 16189514 direct interaction X 2 Q53G59 Q16630 two hybrid 16189514 direct interaction X 2 Q53G59 Q9NP79 two hybrid 16189514 direct interaction X 2 Q9UH77 Q53G59 two hybrid 25416956 direct interaction X 2 A8K031 Q53G59 two hybrid 16189514 direct interaction X 2 Q53G59 two hybrid 18303015 - X 2 Q53G59 in vivo 18303015 - X 2 Q53G59 A0A024R178 two hybrid 16189514 - X 2 Q53G59 A0A024R475 in vitro 18303015 - X 2 Q53G59 A0A024RB45 two hybrid 16189514 - X 2 Q53G59 A0A024RB45 two hybrid 16189514 - X 2 Q53G59 Q53G59 two hybrid 16189514 - X 2 Q53G59 Q7Z614-4 two hybrid 16189514 - X 2 Q53G59 two hybrid 18303015 - X 2 Q53G59 in vivo 18303015 - X 2 Q53G59 A0A024R475 in vitro 18303015 - X 2 Q53G59 A0A024R178 two hybrid 16189514 - X 2 Q53G59 Q7Z614-4 two hybrid 16189514 - X 2 Q53G59 in vivo 18303015 - C 3 Q53G59 in vivo 18303015 - C 3 Q53G59 in vivo 18303015 - C 3 Q9H204 Q53G59 two hybrid 16189514 - X 2 Q9H204 Q53G59 two hybrid 16189514 - X 2 P27658 Q53G59 two hybrid 16189514 - X 2 P27658 Q53G59 two hybrid 16189514 - X 2 Q53G59 Q92997 two hybrid 16189514 - X 2 Q53G59 P54253 two hybrid 16713569 - X 2 Q53G59 Q16630 two hybrid 16189514 - X 2 Q53G59 O95198 two hybrid 16189514 - X 2 Q53G59 Q9NP79 two hybrid 16189514 - X 2 Q53G59 Q92963 in vivo 183031015 - X 2 Q53G59 P54253 two hybrid 16713569 - X 2 Q53G59 Q16630 two hybrid 16189514 - X 2 Q53G59 O95198 two hybrid 16189514 - X 2 Q53G59 Q9NP79 two hybrid 16189514 - X 2 Q53G59 Q8TBB1-2 two hybrid 16189514 - X 2 Q53G59 Q92963 in vivo 183031015 - X 2 Q53G59 Q92997 two hybrid 16189514 - X 2 Q53G59 Q8TBB1-2 two hybrid 16189514 - X 2 P46379-2 Q53G59 two hybrid 16189514 - X 2 P46379-2 Q53G59 two hybrid 16189514 - X 2 A8K031 Q53G59 two hybrid 16189514 - X 2 A8K031 Q53G59 two hybrid 16189514 - X 2 Q53G59 anti tag coimmunoprecipitation 18775313 association C 23 Q53G59 anti tag coimmunoprecipitation 18775313 association C 22 Q53G59 anti tag coimmunoprecipitation 18775313 association C 18 O95050 Q53G59 two hybrid prey pooling approach 25416956 physical association X 2 O95050 Q53G59 two hybrid array 25416956 physical association X 2 O95050 Q53G59 validated two hybrid 25416956 physical association X 2 Q8N4I8 Q53G59 two hybrid prey pooling approach 25416956 physical association X 2 Q8N4I8 Q53G59 two hybrid array 25416956 physical association X 2 Q8N4I8 Q53G59 validated two hybrid 25416956 physical association X 2 Q53G59 P46379 two hybrid pooling approach 16189514 physical association X 2 Q53G59 A0A024RB45 two hybrid pooling approach 16189514 physical association X 2 Q53G59 Q53G59 two hybrid pooling approach 16189514 physical association X 2 Q53G59 A0A024R178 two hybrid pooling approach 16189514 physical association X 2 Q53G59 Q8ZAL3 two hybrid pooling approach 20711500 physical association X 2 Q53G59 P03346 two hybrid array 22458338 physical association X 2 Q53G59 P03346 two hybrid pooling approach 22458338 physical association X 2 Q53G59 Q53G59 two hybrid array 25416956 physical association X 2 Q53G59 A2RRL9 two hybrid prey pooling approach 25416956 physical association X 2 Q53G59 P21333-2 two hybrid prey pooling approach 25416956 physical association X 2 Q53G59 P46379 two hybrid prey pooling approach 25416956 physical association X 2 Q53G59 P09619 two hybrid prey pooling approach 25416956 physical association X 2 Q53G59 Q00013 two hybrid prey pooling approach 25416956 physical association X 2 Q53G59 A0A024R475 two hybrid prey pooling approach 25416956 physical association X 2 Q53G59 Q6IQ55 two hybrid prey pooling approach 25416956 physical association X 2 Q53G59 Q6UXH8 two hybrid prey pooling approach 25416956 physical association X 2 Q53G59 Q8N205 two hybrid prey pooling approach 25416956 physical association X 2 Q53G59 Q8N5L8 two hybrid prey pooling approach 25416956 physical association X 2 Q53G59 A0A024R302 two hybrid prey pooling approach 25416956 physical association X 2 Q53G59 Q9BXJ5 two hybrid prey pooling approach 25416956 physical association X 2 Q53G59 Q96HA8 two hybrid prey pooling approach 25416956 physical association X 2 Q53G59 A0A024RB45 two hybrid prey pooling approach 25416956 physical association X 2 Q53G59 A2RRL9 two hybrid array 25416956 physical association X 2 Q53G59 P21333-2 two hybrid array 25416956 physical association X 2 Q53G59 P46379 two hybrid array 25416956 physical association X 2 Q53G59 P09619 two hybrid array 25416956 physical association X 2 Q53G59 Q00013 two hybrid array 25416956 physical association X 2 Q53G59 A0A024R475 two hybrid array 25416956 physical association X 2 Q53G59 Q6IQ55 two hybrid array 25416956 physical association X 2 Q53G59 Q6UXH8 two hybrid array 25416956 physical association X 2 Q53G59 Q8N205 two hybrid array 25416956 physical association X 2 Q53G59 Q8N5L8 two hybrid array 25416956 physical association X 2 Q53G59 A0A024R302 two hybrid array 25416956 physical association X 2 Q53G59 Q9BXJ5 two hybrid array 25416956 physical association X 2 Q53G59 Q96HA8 two hybrid array 25416956 physical association X 2 Q53G59 A0A024RB45 two hybrid array 25416956 physical association X 2 Q53G59 A2RRL9 validated two hybrid 25416956 physical association X 2 Q53G59 P21333-2 validated two hybrid 25416956 physical association X 2 Q53G59 P09619 validated two hybrid 25416956 physical association X 2 Q53G59 A0A024R475 validated two hybrid 25416956 physical association X 2 Q53G59 P46379 validated two hybrid 25416956 physical association X 2 Q53G59 Q00013 validated two hybrid 25416956 physical association X 2 Q53G59 Q6IQ55 validated two hybrid 25416956 physical association X 2 Q53G59 A0A024R302 validated two hybrid 25416956 physical association X 2 Q53G59 Q8N205 validated two hybrid 25416956 physical association X 2 Q53G59 Q8N5L8 validated two hybrid 25416956 physical association X 2 Q53G59 Q6UXH8 validated two hybrid 25416956 physical association X 2 Q53G59 Q96HA8 validated two hybrid 25416956 physical association X 2 Q53G59 Q9BXJ5 validated two hybrid 25416956 physical association X 2 Q53G59 A0A024RB45 validated two hybrid 25416956 physical association X 2 Q9H204 Q53G59 two hybrid pooling approach 16189514 physical association X 2 P27658 Q53G59 two hybrid pooling approach 16189514 physical association X 2 Q7Z7H8 Q53G59 two hybrid prey pooling approach 25416956 physical association X 2 Q7Z7H8 Q53G59 two hybrid array 25416956 physical association X 2 Q7Z7H8 Q53G59 validated two hybrid 25416956 physical association X 2 Q53G59 Q9UBV8 pull down 16189514 physical association X 2 Q53G59 Q7Z614 two hybrid pooling approach 16189514 physical association X 2 Q53G59 Q8TBB1 two hybrid pooling approach 16189514 physical association X 2 Q53G59 O95198 two hybrid pooling approach 16189514 physical association X 2 Q53G59 Q92997 two hybrid pooling approach 16189514 physical association X 2 Q53G59 Q9UBV8 two hybrid pooling approach 16189514 physical association X 2 Q53G59 Q16630 two hybrid pooling approach 16189514 physical association X 2 Q53G59 Q9NP79 two hybrid pooling approach 16189514 physical association X 2 Q53G59 P54253 two hybrid array 16713569 physical association X 2 Q53G59 P54253 pull down 16713569 physical association X 2 Q53G59 Q8ZDJ6 two hybrid pooling approach 20711500 physical association X 2 Q53G59 O95198 two hybrid 21516116 physical association X 2 Q53G59 A0A024R7Z5 two hybrid prey pooling approach 25416956 physical association X 2 Q53G59 P49765 two hybrid prey pooling approach 25416956 physical association X 2 Q53G59 Q7Z614 two hybrid prey pooling approach 25416956 physical association X 2 Q53G59 Q7Z6J4 two hybrid prey pooling approach 25416956 physical association X 2 Q53G59 Q17RA1 two hybrid prey pooling approach 25416956 physical association X 2 Q53G59 Q7KZS0 two hybrid prey pooling approach 25416956 physical association X 2 Q53G59 Q8IV04 two hybrid prey pooling approach 25416956 physical association X 2 Q53G59 Q9UBV8 two hybrid prey pooling approach 25416956 physical association X 2 Q53G59 A0A024R7Z5 two hybrid array 25416956 physical association X 2 Q53G59 P49765 two hybrid array 25416956 physical association X 2 Q53G59 Q7Z614 two hybrid array 25416956 physical association X 2 Q53G59 Q7Z6J4 two hybrid array 25416956 physical association X 2 Q53G59 Q7KZS0 two hybrid array 25416956 physical association X 2 Q53G59 Q17RA1 two hybrid array 25416956 physical association X 2 Q53G59 Q8IV04 two hybrid array 25416956 physical association X 2 Q53G59 Q9UBV8 two hybrid array 25416956 physical association X 2 Q53G59 A0A024R7Z5 validated two hybrid 25416956 physical association X 2 Q53G59 Q7KZS0 validated two hybrid 25416956 physical association X 2 Q53G59 Q9UBV8 validated two hybrid 25416956 physical association X 2 Q53G59 Q17RA1 validated two hybrid 25416956 physical association X 2 Q53G59 Q7Z614 validated two hybrid 25416956 physical association X 2 Q53G59 Q7Z6J4 validated two hybrid 25416956 physical association X 2 Q53G59 Q8IV04 validated two hybrid 25416956 physical association X 2 Q53G59 P49765 validated two hybrid 25416956 physical association X 2 A8K031 Q53G59 two hybrid pooling approach 16189514 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B KLHL12 CAND1 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_206611 prey bait NDC80 KLHL12 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0468(hprd)|(intact)|MI:0471(mint)|MI:0471(mint) BIOGRID_79214|HPRD_22723|UniProt_152060|MINT_37420|MINT_66601 bait|-|unspecified role|bait|bait prey|-|unspecified role|prey|prey DRD4 KLHL12 MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 18303015,20100572 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(biogrid) HPRD_33178|BIOGRID_140778|BIOGRID_140777 -|prey|prey -|bait|bait UBC KLHL12 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16196087,18303015,21139048,21906983,21963094 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_265950|BIOGRID_117376|BIOGRID_143212|BIOGRID_177075|BIOGRID_167650 bait|prey|bait|bait|bait prey|bait|prey|prey|prey ARHGDIB KLHL12 MI:0004(affinity chromatography technology) 18303015 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_117370 bait prey BAG6 KLHL12 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|- MI:0471(mint)|(biogrid)|(intact)|MI:0471(mint)|MI:0468(hprd) MINT_37834|BIOGRID_79597|UniProt_152442|MINT_67017|HPRD_20657 bait|bait|unspecified role|bait|- prey|prey|unspecified role|prey|- NEDD8 KLHL12 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_206824 bait prey KLHL12 COPS6 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_205786 prey bait CUL3 KLHL12 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0493(in vivo) 16547521,17543862,18303015,19295130,21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association)|- (biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd)|(biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_201994|BIOGRID_117372|BIOGRID_221285|BIOGRID_117371|HPRD_33180|BIOGRID_200510|BIOGRID_130300|HPRD_40066 bait|bait|bait|prey|-|bait|bait|- prey|prey|prey|bait|-|prey|prey|- KLHL12 PRR13 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|- MI:0471(mint)|MI:0471(mint)|(biogrid)|(intact)|MI:0468(hprd) MINT_36726|MINT_65878|BIOGRID_78695|UniProt_151553|HPRD_23798 prey|prey|prey|unspecified role|- bait|bait|bait|unspecified role|- COL8A1 KLHL12 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(intact) HPRD_20371|BIOGRID_79646|UniProt_152492 -|bait|unspecified role -|prey|unspecified role KLHL12 DVL3 MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0018(two hybrid) 16189514,16547521 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|- (biogrid)|(biogrid)|(intact)|MI:0468(hprd) BIOGRID_79760|BIOGRID_130299|UniProt_152604|HPRD_21710 prey|prey|unspecified role|- bait|bait|unspecified role|- KLHL12 RIT1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0493(in vivo) 18303015,183031015 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|-|- (biogrid)|(biogrid)|MI:0468(hprd)|MI:0468(hprd) BIOGRID_117374|BIOGRID_117373|HPRD_33182|HPRD_40066 prey|bait|-|- bait|prey|-|- KLHL12 COPS5 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_205308 prey bait KLHL12 VTA1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|-|MI:0915(physical association) MI:0471(mint)|(biogrid)|MI:0471(mint)|MI:0468(hprd)|(intact) MINT_38443|BIOGRID_80051|MINT_67652|HPRD_23412|UniProt_152895 prey|prey|prey|-|unspecified role bait|bait|bait|-|unspecified role KLHL12 uniprotkb:(gene name) MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint) MINT_67068|MINT_37885 prey|prey bait|bait KLHL12 LNX1 MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|(intact)|(biogrid)|MI:0471(mint)|MI:0471(mint) HPRD_23847|UniProt_152449|BIOGRID_79603|MINT_67023|MINT_37840 -|unspecified role|bait|bait|bait -|unspecified role|prey|prey|prey KLHL12 DKFZp586M1622 MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint) MINT_38002|MINT_67185 prey|prey bait|bait KLHL12 MED28 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(intact)|MI:0471(mint)|MI:0471(mint) HPRD_23844|BIOGRID_78956|UniProt_151809|MINT_66365|MINT_37184 -|bait|unspecified role|bait|bait -|prey|unspecified role|prey|prey KLHL12 PEF1 MI:0096(pull down)|MI:0096(pull down) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_82521|UniProt_152726 prey|unspecified role bait|unspecified role UBXN7 KLHL12 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 18775313 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0914(association) (intact)|(biogrid)|(intact)|(intact)|(intact) UniProt_183205|BIOGRID_148851|UniProt_97401|UniProt_97407|UniProt_183211 bait|bait|bait|bait|bait prey|prey|prey|prey|prey KLHL2 KLHL12 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down) 15383316,16189514,21516116 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association) MI:0471(mint)|(intact)|(biogrid)|(biogrid)|MI:0471(mint)|MI:0468(hprd)|(intact) MINT_67038|UniProt_114853|BIOGRID_79619|BIOGRID_210066|MINT_37855|HPRD_23340|UniProt_152465 bait|prey|bait|prey|bait|-|unspecified role prey|bait|prey|bait|prey|-|unspecified role ARAF KLHL12 MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|- (intact)|(biogrid)|MI:0468(hprd) UniProt_153892|BIOGRID_81065|HPRD_21370 unspecified role|bait|- unspecified role|prey|- ATXN1 KLHL12 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0397(two hybrid array)|MI:0096(pull down)|MI:0397(two hybrid array)|MI:0096(pull down) 16713569 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(intact)|MI:0471(mint)|(intact)|MI:0471(mint) HPRD_19244|BIOGRID_215282|MINT_83098|MINT_50810|BIOGRID_215972|UniProt_86538|MINT_82282|UniProt_85867|MINT_49994 -|bait|bait|bait|bait|unspecified role|bait|bait|bait -|prey|prey|prey|prey|unspecified role|prey|prey|prey EZH2 KLHL12 MI:0004(affinity chromatography technology) 24457600 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_305775 bait prey CPSF6 KLHL12 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0471(mint)|MI:0468(hprd)|(intact)|MI:0471(mint)|(biogrid) MINT_38125|HPRD_22519|UniProt_152738|MINT_67308|BIOGRID_79891 bait|-|unspecified role|bait|bait prey|-|unspecified role|prey|prey UBXN1 KLHL12 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 18775313 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0915(physical association) (intact)|(intact)|(biogrid) UniProt_183208|UniProt_97404|BIOGRID_149377 bait|bait|bait prey|prey|prey KLHL12 SNX20 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0468(hprd)|MI:0471(mint)|(intact)|MI:0471(mint) BIOGRID_79192|HPRD_23846|MINT_37398|UniProt_152037|MINT_66579 bait|-|bait|unspecified role|bait prey|-|prey|unspecified role|prey KLHL12 ARAF MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint) MINT_40152|MINT_69525 prey|prey bait|bait KLHL12 DCUN1D1 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_205988 prey bait

PPI - HINT Gene A Gene B PMID Method Quality UBXN7 KLHL12 18775313,18775313,26389662 0007,0004,0004 LC DRD4 KLHL12 18303015,20100572,27155323,18303015,26717573,20100572 0004,0004,0004,0018,0004,0415 LC CUL3 KLHL12 18303015,21145461,16547521,19295130,17543862 0004,0004,0004,0004,0004 LC,HT NEDD8 KLHL12 21145461 0004 HT KLHL12 COPS6 21145461 0004 HT KLHL12 CAND1 21145461 0004 HT KLHL12 COPS5 21145461 0004 HT KLHL12 MED12 26496610,26496610 0007,0004 HT KLHL12 DCUN1D1 21145461 0004 HT KLHL12 CEP170P1 26496610 0007 HT KLHL12 MAP1LC3B 20562859 0007 HT KLHL12 MAP1LC3A 20562859 0007 HT CUL3 KLHL12 21145461 0004 HT NEDD8 KLHL12 21145461 0004 HT KLHL12 COPS6 21145461 0004 HT KLHL12 CAND1 21145461 0004 HT KLHL12 COPS5 21145461 0004 HT KLHL12 MED12 26496610,26496610 0007,0004 HT KLHL12 DCUN1D1 21145461 0004 HT KLHL12 CEP170P1 26496610 0007 HT KLHL12 MAP1LC3B 20562859 0007 HT KLHL12 MAP1LC3A 20562859 0007 HT UBXN7 KLHL12 18775313,18775313,26389662 0007,0004,0004 LC DRD4 KLHL12 18303015,20100572,27155323,18303015,26717573,20100572 0004,0004,0004,0018,0004,0415 LC CUL3 KLHL12 18303015,16547521,19295130,17543862 0004,0004,0004,0004 LC KNTC2 KLHL12 16189514,16189514 0398,0018 HT SDCBP KLHL12 27107012,25416956,25416956,25416956,25416956,27107012 1356,1112,0397,0018,1356,2215 HT DVL2 KLHL12 27107012,27107012 1356,2215 HT NDC80 KLHL12 16189514,16189514 0398,0018 HT INMT KLHL12 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT KLHL2 KLHL12 16189514,21516116,16189514 0398,0018,0018 HT PDGFRB KLHL12 25416956,25416956,25416956 1112,0397,1356 HT ARAF KLHL12 16189514,16189514 0398,0018 HT FLNA KLHL12 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT DRD4 KLHL12 18303015,20100572,18303015,20100572 0004,0004,0018,0415 LC COL8A1 KLHL12 16189514,16189514 0398,0018 HT BAG6 KLHL12 16189514,25416956,25416956,25416956,16189514,25416956 0398,1112,0397,0018,0018,1356 HT MTNR1A KLHL12 26514267 0018 LC VEGFB KLHL12 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT ATXN1 KLHL12 16713569,16713569,16713569,16713569 0096,0397,0004,0018 HT UBE2I KLHL12 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT MPP1 KLHL12 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT CUL3 KLHL12 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT DGCR6 KLHL12 24722188 0018 HT CPSF6 KLHL12 16189514,16189514 0398,0018 HT KLHL12 KLHL12 27107012,16189514,25416956,25416956,16189514,27107012 1356,0398,0397,0018,0018,2215 HT KLHL12 Q59F04 25416956 0018 HT KLHL12 TTBK2 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT KLHL12 CRTC3 27107012,27107012 1356,2215 HT KLHL12 CCBE1 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT KLHL12 SNX20 16189514,25416956,25416956,25416956,16189514,25416956 0398,1112,0397,0018,0018,1356 HT KLHL12 FGD2 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT KLHL12 MRPL10 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT KLHL12 TBC1D10C 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT KLHL12 GLYCTK 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT KLHL12 SYNE4 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT KLHL12 RPP25L 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT KLHL12 LNX1 16189514,16189514 0398,0018 HT KLHL12 DVL3 16189514,16189514 0398,0018 HT KLHL12 WDYHV1 27107012,25416956,25416956,25416956,25416956,27107012 1356,1112,0397,0018,1356,2215 HT KLHL12 CARD10 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT KLHL12 C1QTNF2 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT KLHL12 ZBP1 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT KLHL12 MED28 16189514,16189514 0398,0018 HT KLHL12 VTA1 16189514,16189514 0398,0018 HT KLHL12 PRR13 16189514,25416956,25416956,25416956,16189514,25416956 0398,1112,0397,0018,0018,1356 HT KLHL12 PEF1 16189514,16189514,25416956,25416956,25416956,25416956 0398,0096,1112,0397,0018,1356 HT KLHL12 DKFZP586M1622 16189514 0018 HT KLHL12 KLHL3 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT KLHL12 TAOK2 24722188 0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9H492 Q53G59 MAP1LC3A KLHL12 0.126 20562859 Q9GZQ8 Q53G59 MAP1LC3B KLHL12 0.126 20562859 Q9NRR4 Q53G59 DROSHA KLHL12 0.126 24778252 Q53G59 P0CG48 KLHL12 UBC 0.126 16196087 Q7KZS0 Q53G59 UBE2I {ECO:0000313|EMBL:EAW85674.1} KLHL12 0.332 25416956 Q7L5N1 Q53G59 COPS6 KLHL12 0.126 21145461 Q7LAP4 Q53G59 VEGFB {ECO:0000313|EMBL:AAL79001.1} KLHL12 0.332 25416956 Q86VP6 Q53G59 CAND1 KLHL12 0.126 21145461 Q53G59 P03225 KLHL12 P03225 0.126 22810586 Q9Z0Y1 Q53G59 DCTN3 KLHL12 0.236 26496610 Q8N5I2 Q53G59 ARRDC1 KLHL12 0.236 unassigned1304 Q8N5L8 Q53G59 RPP25L KLHL12 0.583 25416956,unassigned1304 Q9UBV8 Q53G59 PEF1 KLHL12 0.681 25416956,16189514,unassigned1304 Q8N6K4 Q53G59 Q8N6K4 KLHL12 0.236 unassigned1304 Q53G59 P03346 KLHL12 GAG 0.236 22458338 Q8N8B7 Q53G59 TCEANC KLHL12 0.236 unassigned1304 Q93074 Q53G59 MED12 KLHL12 0.236 26496610 Q96T60 Q53G59 PNKP KLHL12 0.236 unassigned1304 Q53G59 Q13671 KLHL12 RIN1 0.236 unassigned1304 Q9C0E8 Q53G59 LNP KLHL12 0.236 unassigned1304 Q53G59 Q15691 KLHL12 MAPRE1 0.236 unassigned1304 Q53G59 Q3MIN7 KLHL12 RGL3 0.236 unassigned1304 Q53G59 Q04323 KLHL12 UBXN1 0.236 18775313 Q53G59 P21917 KLHL12 DRD4 0.731 27155323,26717573,20100572,18303015 Q53G59 O95050 KLHL12 INMT 0.583 25416956,unassigned1304 Q53G59 O14641 KLHL12 DVL2 0.236 27107012 Q53G59 A0A087WWA7 KLHL12 DVL1 {ECO:0000313|ENSEMBL:ENSP00000480077} 0.236 unassigned1304 Q53G59 P41271 KLHL12 NBL1 0.236 unassigned1304 Q53G59 Q00013 KLHL12 MPP1 0.583 25416956,unassigned1304 Q53G59 P54253 KLHL12 ATXN1 0.583 16713569 Q71SY5 Q53G59 MED25 KLHL12 0.236 unassigned1304 Q7Z7H8 Q53G59 MRPL10 KLHL12 0.454 25416956 Q86YD7 Q53G59 FAM90A1 KLHL12 0.236 unassigned1304 Q9H4M7 Q53G59 PLEKHA4 KLHL12 0.236 unassigned1304 Q9H204 Q53G59 MED28 KLHL12 0.286 16189514 Q9NZ81 Q53G59 PRR13 KLHL12 0.702 25416956,16189514,unassigned1304 Q9P1Z0 Q53G59 ZBTB4 KLHL12 0.236 unassigned1304 Q5HY54 Q53G59 FLNA KLHL12 0.236 unassigned1304 Q6IQ55 Q53G59 TTBK2 KLHL12 0.583 25416956,unassigned1304 Q61545 Q53G59 EWSR1 KLHL12 0.236 26496610 Q6TFL4 Q53G59 KLHL24 KLHL12 0.236 unassigned1304 Q53G59 P41182 KLHL12 BCL6 0.236 unassigned1304 Q8BGH2 Q53G59 SAMM50 KLHL12 0.236 26496610 Q8IV04 Q53G59 TBC1D10C KLHL12 0.583 25416956,unassigned1304 Q53G59 O94888 KLHL12 UBXN7 0.332 18775313,26389662 Q6UXH8 Q53G59 CCBE1 KLHL12 0.583 25416956,unassigned1304 Q53G59 O95198 KLHL12 KLHL2 0.712 16189514,unassigned1304,21516116,15383316 Q53G59 P46379 KLHL12 BAG6 0.702 25416956,16189514,unassigned1304 Q53G59 P49765 KLHL12 VEGFB 0.376 unassigned1304,25416956 Q53G59 O00560 KLHL12 SDCBP 0.681 25416956,27107012,unassigned1304 Q96HA8 Q53G59 WDYHV1 KLHL12 0.681 25416956,27107012,unassigned1304 Q9UH77 Q53G59 KLHL3 KLHL12 0.376 unassigned1304,25416956 Q7Z614 Q53G59 SNX20 KLHL12 0.702 25416956,16189514,unassigned1304 Q7Z6J4 Q53G59 FGD2 KLHL12 0.454 25416956 Q53G59 P21333 KLHL12 FLNA 0.454 25416956 Q53G59 Q13618 KLHL12 CUL3 0.876 25416956,16547521,21145461,18303015,17543862,unassigned1304,19295130 Q53G59 Q53G59 KLHL12 KLHL12 0.772 25416956,16189514,27107012,unassigned1304 Q92905 Q53G59 COPS5 KLHL12 0.126 21145461 Q92963 Q53G59 RIT1 KLHL12 0.376 18303015 Q8ZAL3 Q53G59 METE KLHL12 0.126 20711500 Q8ZDJ6 Q53G59 ACKA KLHL12 0.126 20711500 Q96GG9 Q53G59 DCUN1D1 KLHL12 0.126 21145461 Q53G59 P32121 KLHL12 ARRB2 0.21 27155323 Q96L14 Q53G59 CEP170P1 KLHL12 0.126 26496610 Q9BWT7 Q53G59 CARD10 KLHL12 0.183 25416956 Q9BXJ5 Q53G59 C1QTNF2 KLHL12 0.583 25416956,unassigned1304 Q53G59 P27658 KLHL12 COL8A1 0.454 16189514,unassigned1304 Q9UL54 Q53G59 TAOK2 KLHL12 0.183 24722188 Q53G59 A2RRL9 KLHL12 ZBP1 {ECO:0000313|EMBL:AAI31707.1} 0.332 25416956 Q53G59 P48039 KLHL12 MTNR1A 0.183 26514267 Q53G59 Q14129 KLHL12 DGCR6 0.183 24722188 Q53G59 P49407 KLHL12 ARRB1 0.21 27155323 Q53G59 Q05021 KLHL12 TAF7 0.332 27107014 Q53G59 P63279 KLHL12 UBE2I 0.183 25416956 Q53G59 Q15843 KLHL12 NEDD8 0.126 21145461 Q53G59 Q15910 KLHL12 EZH2 0.126 24457600 Q53G59 Q16630 KLHL12 CPSF6 0.286 16189514 Q53G59 O14777 KLHL12 NDC80 0.286 16189514 Q53G59 P09619 KLHL12 PDGFRB 0.583 25416956,unassigned1304 Q53G59 P10398 KLHL12 ARAF 0.286 16189514 Q53G59 P32502 KLHL12 GCD7 0.332 27107014 Q53G59 P53286 KLHL12 BTN2 0.332 27107014 Q53G59 P53953 KLHL12 SFB2 0.332 27107014 Q53G59 Q06132 KLHL12 SGD1 0.332 27107014 Q53G59 Q17RA1 KLHL12 CARD10 {ECO:0000313|EMBL:AAI17404.1} 0.332 25416956 Q6UUV7 Q53G59 CRTC3 KLHL12 0.236 27107012 Q8IVS8 Q53G59 GLYCTK KLHL12 0.454 25416956 Q8N205 Q53G59 SYNE4 KLHL12 0.454 25416956 Q8N4I8 Q53G59 KLHL3 {ECO:0000313|EMBL:AAH34035.1} KLHL12 0.332 25416956 Q8TBB1 Q53G59 LNX1 KLHL12 0.454 16189514,unassigned1304 Q92997 Q53G59 DVL3 KLHL12 0.569 16547521,16189514,unassigned1304 Q9H171 Q53G59 ZBP1 KLHL12 0.183 25416956 Q9NP79 Q53G59 VTA1 KLHL12 0.286 16189514

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 SDCBP KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database DVL2 KLHL12 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database NDC80 KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database DCTN3 KLHL12 MI:0362 inference MI:0461 interaction database SEC24D KLHL12 MI:0362 inference MI:0461 interaction database UBXN7 KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database INMT KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database KLHL2 KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database SEC24A KLHL12 MI:0362 inference MI:0461 interaction database SEC24B KLHL12 MI:0362 inference MI:0461 interaction database PDGFRB KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database UBB KLHL12 MI:0362 inference MI:1106 pathways database UBC KLHL12 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ARAF KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database FLNA KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database DRD4 KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database COL8A1 KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database ARRB2 KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database BAG6 KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database MTNR1A KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database ARRB1 KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database VEGFB KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database EIF2B2 KLHL12 MI:0362 inference MI:0461 interaction database ARHGDIB KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database SEC24C KLHL12 MI:0362 inference MI:0461 interaction database ATXN1 KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database RBX1 KLHL12 MI:0362 inference MI:1106 pathways database RPS27A KLHL12 MI:0362 inference MI:1106 pathways database UBA52 KLHL12 MI:0362 inference MI:1106 pathways database UBE2I KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database MPP1 KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database EWSR1 KLHL12 MI:0362 inference MI:0461 interaction database UBXN1 KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database CUL3 KLHL12 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database DGCR6 KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database TAF7 KLHL12 MI:0362 inference MI:0461 interaction database NEDD8 KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database EZH2 KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database CPSF6 KLHL12 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 NOM1 MI:0362 inference MI:0461 interaction database KLHL12 TAF7L MI:0362 inference MI:0461 interaction database KLHL12 TTBK2 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 CRTC3 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 CCBE1 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 COPS6 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 SNX20 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 FGD2 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 MRPL10 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 CAND1 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 TBC1D10C MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 GLYCTK MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 SYNE4 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 RPP25L MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 LNX1 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 COPS5 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 RIT1 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 DVL3 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database KLHL12 MED12 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 DCUN1D1 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 WDYHV1 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 CEP170P1 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 CARD10 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 C1QTNF2 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 MAP1LC3B MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 ZBP1 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 MED28 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 MAP1LC3A MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 VTA1 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 DROSHA MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 PRR13 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 PEF1 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 KLHL3 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 TAOK2 MI:0045 experimental interaction detection MI:0461 interaction database KLHL12 SAMM50 MI:0362 inference MI:0461 interaction database