Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 1 205061192 rs10158848 C T rs10158848 8.74E-07 Red blood cell traits HPOID:0001877 DOID:74 C intron GWASdb_trait 1 205063949 rs3738154 C T rs3738154 4.11E-04 Insulin resistance HPOID:0000855 DOID:9352 T intron GWASdb_trait 1 205065733 rs11577406 G T rs11577406 4.73E-07 Red blood cell traits HPOID:0001877 DOID:74 G intron GWASdb_trait 1 205070522 rs11240357 C T rs11240357 8.89E-04 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait 1 205070573 rs11240358 G A rs11240358 4.12E-05 Frontotemporal lobar degeneration with TDP-43 inclusions, in brain HPOID:0000707 DOID:1307 G intron GWASdb_trait 1 205070573 rs11240358 G A rs11240358 8.91E-04 Response to taxane treatment (placlitaxel) HPOID:0100526 DOID:1324 G intron GWASdb_trait 1 205074424 rs3738155 C T rs3738155 3.24E-07 Red blood cell traits HPOID:0001877 DOID:74 C intron GWASdb_trait 1 205074854 rs12125465 C A rs12125465 3.13E-07 Red blood cell traits HPOID:0001877 DOID:74 C intron GWASdb_trait 1 205078247 rs4950982 T C rs4950982 7.95E-04 Stroke HPOID:0001297 DOID:6713 C intron GWASdb_trait 1 205078247 rs4950982 T C rs4950982 8.24E-05 Waist Circumference HPOID:0001513 DOID:9970 C intron GWASdb_trait 1 205083865 rs11240360 T C rs11240360 2.05E-07 Red blood cell traits HPOID:0001877 DOID:74 T intron GWASdb_trait 1 205084120 rs7515178 G A rs7515178 8.51E-05 IgE levels in asthmatics (D.p. specific) HPOID:0002099 DOID:2841 A intron GWASdb_trait

Disease associated variation - GWAS Central Study Name Source Marker Accession Chromosome Marker Start Marker Stop Alleles Gene Section P-value -log(p-value) GWAS of prostate cancer rs7514499 1 205080963 205080963 intronic 0.744514 0.128127131268984 GWAS of prostate cancer rs4950982 1 205078247 205078247 intronic 0.717765 0.144017722761574 GWAS of prostate cancer rs11240359 1 205078167 205078167 intronic 0.576463 0.239228562456891 GWAS of prostate cancer rs3738154 1 205063949 205063949 intronic 0.198159 0.702986198063205

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000117222.13 RBBP5 600697