PTM - CPLM Gene Name UniProt ID Type Position Code RBBP5; RBQ3 Q15291 Acetylation 281 K RBBP5; RBQ3 Q15291 Acetylation 500 K RBBP5; RBQ3 Q15291 Ubiquitination 244 K RBBP5; RBQ3 Q15291 Ubiquitination 256 K

PTM - dbPAF Gene Name UniProt ID Position Type Species RBBP5; RBQ3 Q15291 13 Y Homo sapiens(Human) RBBP5; RBQ3 Q15291 130 S Homo sapiens(Human) RBBP5; RBQ3 Q15291 138 S Homo sapiens(Human) RBBP5; RBQ3 Q15291 180 T Homo sapiens(Human) RBBP5; RBQ3 Q15291 182 S Homo sapiens(Human) RBBP5; RBQ3 Q15291 188 S Homo sapiens(Human) RBBP5; RBQ3 Q15291 193 T Homo sapiens(Human) RBBP5; RBQ3 Q15291 198 T Homo sapiens(Human) RBBP5; RBQ3 Q15291 20 T Homo sapiens(Human) RBBP5; RBQ3 Q15291 211 S Homo sapiens(Human) RBBP5; RBQ3 Q15291 252 T Homo sapiens(Human) RBBP5; RBQ3 Q15291 350 S Homo sapiens(Human) RBBP5; RBQ3 Q15291 388 S Homo sapiens(Human) RBBP5; RBQ3 Q15291 389 S Homo sapiens(Human) RBBP5; RBQ3 Q15291 396 S Homo sapiens(Human) RBBP5; RBQ3 Q15291 440 S Homo sapiens(Human) RBBP5; RBQ3 Q15291 497 S Homo sapiens(Human) RBBP5; RBQ3 Q15291 515 S Homo sapiens(Human) RBBP5; RBQ3 Q15291 525 S Homo sapiens(Human) RBBP5; RBQ3 Q15291 55 T Homo sapiens(Human) RBBP5; RBQ3 Q15291 8 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q15291 K281-ac Acetylation HALYIWEkSIGNLVK Q15291 K500-ac Acetylation KEKDsPFkPKLYKGD Q15291 R162-m1 Methylation VVASFDRrGEYIYTG Q15291 S8-p Phosphorylation MNLELLEsFGQNyPE Q15291 Y13-p Phosphorylation LEsFGQNyPEEADGt Q15291 T20-p Phosphorylation yPEEADGtLDCISMA Q15291 T55-p Phosphorylation IVIWDFLtRGIAKII Q15291 S130-p Phosphorylation VLVCPMksAPVMLTL Q15291 S182-p Phosphorylation ILVLKTDsQDLVASF Q15291 T193-p Phosphorylation VASFRVTtGTSNtTA Q15291 T198-p Phosphorylation VTtGTSNtTAIKSIE Q15291 S211-p Phosphorylation IEFARKGsCFLINTA Q15291 T252-p Phosphorylation LQDLVNRtPWKKCCF Q15291 Y345-p Phosphorylation ELDENVEyEEREsEF Q15291 S350-p Phosphorylation VEyEEREsEFDIEDE Q15291 S388-p Phosphorylation DPIAAFCssDEELED Q15291 S389-p Phosphorylation PIAAFCssDEELEDS Q15291 S497-p Phosphorylation SKGKEKDsPFkPKLY Q15291 S515-p Phosphorylation RGLPLEGsAKGKVQA Q15291 S525-p Phosphorylation GKVQAELsQPLTAGG Q15291 K129-ub Ubiquitination KVLVCPMksAPVMLT Q15291 K244-ub Ubiquitination GEPEPMQkLQDLVNR

PTM - dbPTM UniProt ID Position Code Type Resources References Q15291 182 S Phosphorylation Swiss-Prot 1010711 17525332 Q15291 193 T Phosphorylation Swiss-Prot 1010711 17525332 Q15291 281 K Acetylation Swiss-Prot 1010711 19608861 Q15291 350 S Phosphorylation Swiss-Prot 1010711 17081983 Q15291 388 S Phosphorylation Swiss-Prot 1010711 17081983 Q15291 389 S Phosphorylation Swiss-Prot 1010711 17081983 Q15291 497 S Phosphorylation Swiss-Prot 1010711 17081983 Q15291 252 T Phosphorylation Swiss-Prot 1010711 - Q15291 182 S Phosphorylation PhosphoELM.10011 17525332 Q15291 193 T Phosphorylation PhosphoELM.10011 17525332 Q15291 244 K Ubiquitylation Phosphositeplus.1010730 21890473 Q15291 281 K Acetylation Phosphositeplus.1010730 19608861 Q15291 130 S Phosphorylation Phosphositeplus.1010730 19664994 Q15291 182 S Phosphorylation Phosphositeplus.1010730 17525332 Q15291 350 S Phosphorylation Phosphositeplus.1010730 20363803 Q15291 388 S Phosphorylation Phosphositeplus.1010730 20068231;20363803 Q15291 389 S Phosphorylation Phosphositeplus.1010730 20068231;20363803 Q15291 497 S Phosphorylation Phosphositeplus.1010730 17081983;20068231;20363803;20815410;21406692 Q15291 525 S Phosphorylation Phosphositeplus.1010730 18077418;20068231;21406692 Q15291 8 S Phosphorylation Phosphositeplus.1010730 19276368 Q15291 193 T Phosphorylation Phosphositeplus.1010730 17525332 Q15291 20 T Phosphorylation Phosphositeplus.1010730 19276368 Q15291 13 Y Phosphorylation Phosphositeplus.1010730 19276368 Q15291 281 K Acetylation HPRD 9.0 19608861 Q15291 130 S Phosphorylation HPRD 9.0 19664994,20068231 Q15291 138 S Phosphorylation HPRD 9.0 20068231 Q15291 182 S Phosphorylation HPRD 9.0 17525332,20068231 Q15291 188 S Phosphorylation HPRD 9.0 20068231 Q15291 350 S Phosphorylation HPRD 9.0 17081983,18452278 Q15291 388 S Phosphorylation HPRD 9.0 17081983,18452278,20068231 Q15291 389 S Phosphorylation HPRD 9.0 17081983,18452278,20068231 Q15291 497 S Phosphorylation HPRD 9.0 17081983,19651622,20068231 Q15291 525 S Phosphorylation HPRD 9.0 18077418,20068231 Q15291 180 T Phosphorylation HPRD 9.0 20068231 Q15291 193 T Phosphorylation HPRD 9.0 17525332 Q15291 350 S Phosphorylation SysPTM 1.1 17081983 Q15291 388 S Phosphorylation SysPTM 1.1 17081983 Q15291 389 S Phosphorylation SysPTM 1.1 17081983 Q15291 497 S Phosphorylation SysPTM 1.1 17081983

PTM - HPRD Symbol Position Code Type References RBBP5 130 S Phosphorylation 19664994,20068231 RBBP5 138 S Phosphorylation 20068231 RBBP5 180 T Phosphorylation 20068231 RBBP5 182 S Phosphorylation 17525332,20068231 RBBP5 188 S Phosphorylation 20068231 RBBP5 193 T Phosphorylation 17525332 RBBP5 281 K Acetylation 19608861 RBBP5 350 S Phosphorylation 17081983,18452278 RBBP5 388 S Phosphorylation 17081983,18452278,20068231 RBBP5 389 S Phosphorylation 17081983,18452278,20068231 RBBP5 497 S Phosphorylation 17081983,19651622,20068231 RBBP5 525 S Phosphorylation 18077418,20068231

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q15291 182 S 17525332 HTP Phosphorylation Q15291 193 T 17525332 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q15291 252 Phosphothreonine; by CDK1 7558034 Q15291 350 Phosphoserine 17081983 Q15291 388 Phosphoserine 20068231 Q15291 389 Phosphoserine 20068231 Q15291 497 Phosphoserine; by CDK1 7558034 Q15291 525 Phosphoserine 21406692

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type RBBP5 IPI00021035 K 281 ALYIWEaKSIGNLV acetylation RBBP5 IPI00021035 S 388 PIAAFCpSSDEELE phosphorylation RBBP5 IPI00021035 S 389 IAAFCSpSDEELED phosphorylation RBBP5 IPI00021035 S 497 KGKEKDpSPFKPKL phosphorylation RBBP5 IPI00478230 S 350 EYEEREpSEFDIED phosphorylation RBBP5 IPI00478230 S 388 PIAAFCpSSDEELE phosphorylation RBBP5 IPI00478230 S 389 IAAFCSpSDEELED phosphorylation RBBP5 IPI00478230 S 497 KGKEKDpSPFKPKL phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 5929 111864 - K Ubiquitination 21139048 5929 111864 - K Ubiquitination 21890473 5929 111864 - K Ubiquitination 24816145 5929 111864 - K Sumoylation 24930734

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID RBBP5 Homo sapiens (Human) 279 "279,EPEPMQKLQDLVN" 279:21890473 RBBP5 Homo sapiens (Human) 117 "117,EPEPMQKLQDLVN" 117:21890473 RBBP5 Homo sapiens (Human) 117 "117,EPEPMQKLQDLVN" 117:21890473 RBBP5 Homo sapiens (Human) 279 "279,EPEPMQKLQDLVN" 279:21890473 RBBP5 Homo sapiens (Human) 244 "244,EPEPMQKLQDLVN" 244:21890473