PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus WDR11 C17orf75 26186194 biogrid exp P P G GP P P G GP P P G GP G P P GP GP G G P GP NAA40 WDR11 26344197 biogrid exp GP GP G G G GP G GP GP G GP GP G G G GP GP G GP G GP GP GP GP GP G GP GP G ALDH1L2 WDR11 26186194 biogrid exp P P G P GP P P P GP P GP P P GP P GP GP WDR11 FBXW11 25515538 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PSMA2 WDR11 26344197 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP G GP GP G HLA-B WDR11 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TMEM17 WDR11 26638075 biogrid,intact exp P GP G GP G P P G GP P P G G P GP GP G P GP GP P P P GP WDR11 TMEM216 26638075 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NTRK1 WDR11 25921289 biogrid exp P P P G P P P P P P P P P P P P P P UBXN7 WDR11 18775313 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WDR11 UBA2 26344197 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP G GP GP G ZNF397 WDR11 26186194 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP G GP GP G PSMA6 WDR11 26344197 biogrid exp P P P P P P P P P P P P P P P P P P P PSMA1 WDR11 26344197 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G PSMA4 WDR11 26344197 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G FAS WDR11 26186194 biogrid exp GP GP G G G GP G G GP GP G GP GP G GP GP G GP G GP GP G G GP G GP GP G NOTCH1 WDR11 23022380 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G XPOT WDR11 26344197 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP G GP GP G G GP G WDR11 GABARAPL1 20562859, 25402006 biogrid,intact exp, pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G GP G GP GP GP G GP GP G ATG2A WDR11 25402006 pred G G G G G GP G G G G G GP GP G G G GP G G G GP G G G G G G G G WDR11 WDR26 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G KLHL22 WDR11 25402006 pred G GP G G G G G GP GP G GP G GP G G GP G G GP G GP G GP GP GP G GP GP G CUL1 WDR11 25402006 pred GP G G G G GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP GP G GP GP G NSMAF WDR11 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP G GP GP GP G GP GP G WDR11 USP44 21836163 pred P P P P P P P P P P P GP G P P P P P P GP ZNF320 WDR11 21836163 pred GP GP G G G GP G GP GP G GP P GP GP G P GP G GP G GP GP GP GP GP G GP GP G OPRK1 WDR11 25402006 pred P P G GP G P G P P P P GP G GP G GP P P P P NBR1 WDR11 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WDR11 KLHDC2 25402006 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP G GP GP G UBR4 WDR11 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G GBAS WDR11 25402006 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WDR11 TMEM160 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G GNGT1 WDR11 23023127 pred P P P G P P KBTBD6 WDR11 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G G GP G G G G G GP G G G G G G CUL3 WDR11 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G CUL4B WDR11 25402006 pred GP GP G G G GP G GP GP G GP GP G GP G GP GP G GP G GP GP GP GP GP G GP GP G WDR11 PLAA 25402006 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP G GP GP G UBR1 WDR11 25402006 pred GP GP G G G GP G GP GP G GP G GP G G GP GP G GP G GP GP GP GP GP G GP GP G WDR11 ATG4B 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G KBTBD7 WDR11 25402006 pred GP G G G G GP G GP GP G GP GP GP G G GP GP G GP G G GP G G GP G GP GP G RGS9 WDR11 23023127 pred G G G G G G G G DDB1 WDR11 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G STBD1 WDR11 25402006 pred G G WDR11 BRWD1 25402006 pred GP P G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP P GP G WDR11 TBC1D2B 25402006 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP G GP GP GP G GP GP G GYG1 WDR11 25402006 pred G G G G G GP G G G G GP G G GP G G GP G GP G G G G GP G G G GP G GYS1 WDR11 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G CUL2 WDR11 25402006 pred GP GP G G G GP G G GP G GP GP GP GP G G GP G GP G GP GP GP G G G GP GP G EXOSC10 WDR11 21836163 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9BZH6 P46531 affinity chromatography technology 23022380 physical association X 2 Q9BZH6 O94888 affinity chromatography technology 18775313 physical association X 2 Q9BZH6 A0A024RAP5 affinity chromatography technology 20562859 physical association X 2 P0CG48 Q9BZH6 affinity chromatography technology 21139048 physical association X 2 P0CG48 Q9BZH6 affinity chromatography technology 21890473 physical association X 2 P0CG48 Q9BZH6 affinity chromatography technology 21906983 physical association X 2 Q9BZH6 chromatin immunoprecipitation assay 15009096 association C 37 Q9BZH6 anti bait coimmunoprecipitation 15009096 association C 37 Q9BZH6 anti tag coimmunoprecipitation 18775313 association C 23 Q9BZH6 anti tag coimmunoprecipitation 18775313 association C 22 Q9BZH6 anti tag coimmunoprecipitation 20562859 physical association C 33

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B WDR11 GABARAPL1 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association) (intact)|(biogrid) UniProt_106867|BIOGRID_125266 prey|prey prey|bait NOTCH1 WDR11 MI:0004(affinity chromatography technology) 23022380 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_246685 bait prey UBC WDR11 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21139048,21890473,21906983 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_173683|BIOGRID_178947|BIOGRID_169654 bait|bait|bait prey|prey|prey UBXN7 WDR11 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 18775313 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association) (intact)|(intact)|(biogrid)|(intact)|(intact) UniProt_183205|UniProt_97401|BIOGRID_148862|UniProt_97407|UniProt_183211 bait|bait|bait|bait|bait prey|prey|prey|prey|prey

PPI - HINT Gene A Gene B PMID Method Quality XPOT WDR11 26344197 0401 HT UBXN7 WDR11 18775313,18775313,26389662 0007,0004,0004 LC PSMA1 WDR11 26344197 0401 HT PSMA2 WDR11 26344197 0401 HT PSMA4 WDR11 26344197 0401 HT PSMA6 WDR11 26344197 0401 HT HLA-B WDR11 26186194 0004 HT ALDH1L2 WDR11 26186194 0004 HT Q59FU8 WDR11 26186194 0004 HT NAA40 WDR11 26344197 0401 HT TMEM17 WDR11 26638075,26638075 1314,1313 HT ZNF397 WDR11 26186194 0004 HT WDR11 GABARAPL1 20562859,20562859 0007,0004 HT WDR11 C17ORF75 26186194 0004 HT WDR11 TMEM216 26638075,26638075 1314,1313 HT WDR11 UBA2 26344197 0401 HT XPOT WDR11 26344197 0401 HT PSMA1 WDR11 26344197 0401 HT PSMA2 WDR11 26344197 0401 HT PSMA4 WDR11 26344197 0401 HT PSMA6 WDR11 26344197 0401 HT HLA-B WDR11 26186194 0004 HT ALDH1L2 WDR11 26186194 0004 HT Q59FU8 WDR11 26186194 0004 HT NAA40 WDR11 26344197 0401 HT TMEM17 WDR11 26638075,26638075 1314,1313 HT ZNF397 WDR11 26186194 0004 HT WDR11 GABARAPL1 20562859,20562859 0007,0004 HT WDR11 C17ORF75 26186194 0004 HT WDR11 TMEM216 26638075,26638075 1314,1313 HT WDR11 UBA2 26344197 0401 HT UBXN7 WDR11 18775313,18775313,26389662 0007,0004,0004 LC XPOT WDR11 26344197 0401 LC PSMA1 WDR11 26344197 0401 LC PSMA2 WDR11 26344197 0401 LC PSMA4 WDR11 26344197 0401 LC PSMA6 WDR11 26344197 0401 LC NAA40 WDR11 26344197 0401 LC WDR11 UBA2 26344197 0401 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9BZH6 P60900 WDR11 PSMA6 0.081 26344197 Q9BZH6 O43592 WDR11 XPOT 0.081 26344197 Q9HAS0 Q9BZH6 C17ORF75 WDR11 0.126 26186194 Q9BZH6 Q8NF99 WDR11 ZNF397 0.126 26186194 Q9BZH6 P25445 WDR11 FAS 0.126 26186194 Q9BZH6 P25786 WDR11 PSMA1 0.081 26344197 Q9BZH6 P25787 WDR11 PSMA2 0.081 26344197 Q9BZH6 P01889 WDR11 HLA-B 0.126 26186194 Q9BZH6 P04629 WDR11 NTRK1 0.126 25921289 Q9P0N5 Q9BZH6 TMEM216 WDR11 0.236 26638075 Q9BZH6 Q86X19 WDR11 TMEM17 0.236 26638075 Q9BZH6 O94888 WDR11 UBXN7 0.332 18775313,26389662 Q9H0R8 Q9BZH6 GABARAPL1 WDR11 0.332 20562859 Q9BZH6 P25789 WDR11 PSMA4 0.081 26344197 Q9BZH6 Q86UY6 WDR11 NAA40 0.081 26344197 Q9UBT2 Q9BZH6 UBA2 WDR11 0.081 26344197 Q9UKB1 Q9BZH6 FBXW11 WDR11 0.126 25515538 Q9BZH6 P46531 WDR11 NOTCH1 0.126 23022380 Q9BZH6 Q3SY69 WDR11 ALDH1L2 0.126 26186194

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 UBXN7 WDR11 MI:0045 experimental interaction detection MI:0461 interaction database HLA-B WDR11 MI:0045 experimental interaction detection MI:0461 interaction database NTRK1 WDR11 MI:0045 experimental interaction detection MI:0461 interaction database UBC WDR11 MI:0045 experimental interaction detection MI:0461 interaction database TAF1 WDR11 MI:0045 experimental interaction detection MI:0461 interaction database FAS WDR11 MI:0045 experimental interaction detection MI:0461 interaction database NOTCH1 WDR11 MI:0045 experimental interaction detection MI:0461 interaction database ALDH1L2 WDR11 MI:0045 experimental interaction detection MI:0461 interaction database TMEM17 WDR11 MI:0045 experimental interaction detection MI:0461 interaction database ZNF397 WDR11 MI:0045 experimental interaction detection MI:0461 interaction database WDR11 GABARAPL1 MI:0045 experimental interaction detection MI:0461 interaction database WDR11 C17orf75 MI:0045 experimental interaction detection MI:0461 interaction database WDR11 TMEM216 MI:0045 experimental interaction detection MI:0461 interaction database WDR11 FBXW11 MI:0045 experimental interaction detection MI:0461 interaction database