PTM - CPLM Gene Name UniProt ID Type Position Code COPS5; CSN5; JAB1 Q92905 Acetylation 47 K COPS5; CSN5; JAB1 Q92905 Ubiquitination 33 K COPS5; CSN5; JAB1 Q92905 Ubiquitination 11 K COPS5; CSN5; JAB1 Q92905 Ubiquitination 30 K COPS5; CSN5; JAB1 Q92905 Ubiquitination 47 K COPS5; CSN5; JAB1 Q92905 Ubiquitination 56 K COPS5; CSN5; JAB1 Q92905 Ubiquitination 191 K COPS5; CSN5; JAB1 Q92905 Ubiquitination 194 K COPS5; CSN5; JAB1 Q92905 Ubiquitination 236 K COPS5; CSN5; JAB1 Q92905 Ubiquitination 326 K COPS5; CSN5; JAB1 Q92905 Ubiquitination 309 K COPS5; CSN5; JAB1 Q92905 Ubiquitination 210 K COPS5; CSN5; JAB1 Q92905 Ubiquitination 34 K COPS5; CSN5; JAB1 Q92905 Ubiquitination 180 K COPS5; CSN5; JAB1 Q92905 Ubiquitination 125 K COPS5; CSN5; JAB1 Q92905 Ubiquitination 43 K

PTM - dbPAF Gene Name UniProt ID Position Type Species COPS5; CSN5; JAB1 Q92905 120 Y Homo sapiens(Human) COPS5; CSN5; JAB1 Q92905 203 Y Homo sapiens(Human) COPS5; CSN5; JAB1 Q92905 261 Y Homo sapiens(Human) COPS5; CSN5; JAB1 Q92905 320 S Homo sapiens(Human) COPS5; CSN5; JAB1 Q92905 54 Y Homo sapiens(Human) COPS5; CSN5; JAB1 Q92905 71 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q92905 K47-ac Acetylation LAAkPWTkDHHYFKy Q92905 K326-ac Acetylation MsQVIKDkLFNQINI Q92905 R282-m1 Methylation QSEAQLGrGsFMLGL Q92905 R294-m1 Methylation LGLETHDrkSEDKLA Q92905 K295-m1 Methylation GLETHDrkSEDKLAK Q92905 S24-p Phosphorylation NNMQEAQsIDEIYkY Q92905 Y54-p Phosphorylation kDHHYFKyCkISALA Q92905 S71-p Phosphorylation KMVMHARsGGNLEVM Q92905 Y203-p Phosphorylation PDEGPSEyQTIPLNK Q92905 S284-p Phosphorylation EAQLGrGsFMLGLET Q92905 S320-p Phosphorylation EAIHGLMsQVIKDkL Q92905 K11-ub Ubiquitination SGSGMAQkTWELANN Q92905 K30-ub Ubiquitination QsIDEIYkYDkkQQQ Q92905 K33-ub Ubiquitination DEIYkYDkkQQQEIL Q92905 K34-ub Ubiquitination EIYkYDkkQQQEILA Q92905 K43-ub Ubiquitination QQEILAAkPWTkDHH Q92905 K47-ub Ubiquitination LAAkPWTkDHHYFKy Q92905 K56-ub Ubiquitination HHYFKyCkISALALL Q92905 K125-ub Ubiquitination AAYIENAkQVGRLEN Q92905 K194-ub Ubiquitination RTYPKGYkPPDEGPS Q92905 K236-ub Ubiquitination FKSSLDRkLLELLWN

PTM - dbPTM UniProt ID Position Code Type Resources References Q92905 2 A Acetylation Swiss-Prot 1010711 18850735;19413330 Q92905 47 K Acetylation Swiss-Prot 1010711 19608861 Q92905 11 K Ubiquitylation Phosphositeplus.1010730 21890473 Q92905 125 K Ubiquitylation Phosphositeplus.1010730 21906983 Q92905 194 K Ubiquitylation Phosphositeplus.1010730 21906983 Q92905 236 K Ubiquitylation Phosphositeplus.1010730 21890473 Q92905 30 K Ubiquitylation Phosphositeplus.1010730 21906983 Q92905 33 K Ubiquitylation Phosphositeplus.1010730 21906983 Q92905 34 K Ubiquitylation Phosphositeplus.1010730 21906983 Q92905 43 K Ubiquitylation Phosphositeplus.1010730 21906983 Q92905 47 K Ubiquitylation Phosphositeplus.1010730 21890473 Q92905 56 K Ubiquitylation Phosphositeplus.1010730 21890473 Q92905 47 K Acetylation Phosphositeplus.1010730 19608861 Q92905 47 K Acetylation HPRD 9.0 19608861 Q92905 120 Y Phosphorylation HPRD 9.0 18669648 Q92905 261 Y Phosphorylation HPRD 9.0 20068231

PTM - HPRD Symbol Position Code Type References COPS5 120 Y Phosphorylation 18669648 COPS5 261 Y Phosphorylation 20068231 COPS5 47 K Acetylation 19608861

PTM - UniProt UniProt ID Position Type PMIDs Q92905 2 N-acetylalanine 18850735

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type COPS5 IPI00009958 K 46 AAKPWTaKDHHYFK acetylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 10987 116183 - K Ubiquitination 19656241 10987 116183 - K Ubiquitination 17623298 10987 116183 - K Ubiquitination 21139048 10987 116183 - K Ubiquitination 21890473 10987 116183 - K Ubiquitination 21906983 10987 116183 - K Ubiquitination 22505724 10987 116183 - K Ubiquitination 23357576 10987 116183 - K Ubiquitination 21963094 10987 116183 - K Neddylation 24654937 10987 116183 - K Ubiquitination 24816145 10987 116183 - K Ubiquitination 25147182 10987 116183 - K Ubiquitination 14993265

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID COPS5 Homo sapiens (Human) 34; 33; 43; 30 "34,IYKYDKKQQQEIL; 33,EIYKYDKKQQQEI; 43,QEILAAKPWTKDK; 30,SIDEIYKYDKKQQ" 34:21906983; 33:21906983; 43:21906983; 30:21906983 COPS5 Homo sapiens (Human) 205; 25; 163; 160 "205,KSSLDRKLLELLW; 25,HYFKYCKISALAL; 163,TYPKGYKPPDEGP; 160,AFRTYPKGYKPPD" 205:21890473; 25:21890473; 163:21890473; 160:21890473 COPS5 Homo sapiens (Human) 34; 33; 236; 191; 43; 125; 11; 56; 47; 30; 194 "34,IYKYDKKQQQEIL; 33,EIYKYDKKQQQEI; 236,KSSLDRKLLELLW; 191,AFRTYPKGYKPPD; 43,QEILAAKPWTKDH; 125,AYIENAKQVGRLE; 11,GSGMAQKTWELAN; 56,HYFKYCKISALAL; 47,AAKPWTKDHHYFK; 30,SIDEIYKYDKKQQ; 194,TYPKGYKPPDEGP" "34:21906983; 33:21906983,21139048; 236:21890473; 191:21890473; 43:21906983; 125:21906983; 11:21890473; 56:21890473; 47:21890473; 30:21890473,21906983; 194:21890473,21906983"