PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus ZNF398 OPTN 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UQCRQ OPTN 20195357 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G GABARAPL2 OPTN 21617041 biogrid exp G GP G G GP GP G GP GP G GP G G G G GP GP G GP G G GP GP G GP G GP GP G OPTN BRE 22863883 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CENPB OPTN 20195357 intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G G GP GP GP GP G OPTN ZNF711 23414517 intact exp GP GP G G GP GP G GP GP G GP P P GP G GP GP GP P G P GP GP P GP GP GP GP OPTN ZNF670 25416956 biogrid,intact exp P P P P P P P P P P P P P P P P P P P P OPTN CYLD 21408173 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP OPTN MACF1 20195357 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G RAB12 OPTN 23357852 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G LNX2 OPTN 21516116 biogrid,mint,intact exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G RPL37A OPTN 20195357 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G OPTN MAP1LC3A 21617041,25026213 biogrid exp G GP G G G GP G G GP G G GP G G G GP GP G GP G G G G G GP G G GP G RAB3IL1 OPTN 26186194 biogrid exp G G G G GP GP G G G G GP G G G G G GP G G G G G G G G G G G G FLII OPTN 10366446 hprd exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CLTC OPTN 23414517 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G EPS15 OPTN 17626244 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G VWF OPTN 23414517 intact exp G G G G GP GP G G GP G G G G G G GP G G G G G G G G G G G G OPTN MAP1LC3B 21617041,23805866,25026213 biogrid,intact exp G GP G G GP GP G GP GP G GP G G G G GP GP G G G G G G GP GP G GP GP G ZNF329 OPTN 25416956 biogrid,intact exp GP GP G P GP G GP GP G GP GP GP G G GP GP GP P G GP GP GP GP G GP GP G MYH3 OPTN 23414517 intact exp P P P P GP P P G FAM175B OPTN 20195357 intact exp GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G FAM189A2 OPTN 21516116 biogrid,mint,intact exp GP GP G G GP GP G GP GP G GP GP G GP G GP GP GP GP G GP GP GP GP GP GP GP GP G NEB OPTN 23414517 intact exp G P G G G G P G G G G G GP G P G OPTN CCDC53 25416956,16189514,21516116 hprd,biogrid,mint,intact exp GP GP G G G GP G G GP G G G G G G G GP G G G G GP G G G G G G WDR20 OPTN 19615732 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP G G GP GP G GP GP G PPARG OPTN 20195357 intact exp GP P P P GP P GP G GP P G GP P P P P GP P YWHAQ OPTN 21903422 innatedb,biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G TNF OPTN 22675546 biogrid exp G G G G G GP G G GP G G G GP G GP GP G GP G G G G GP G GP G G RAB14 OPTN 19702578 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G OPTN ZNF426 23414517 intact exp GP GP GP G GP GP G GP P GP GP G GP GP GP P GP GP P G GP GP YWHAG OPTN 21903422 innatedb,biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G YWHAZ OPTN 21903422 innatedb,biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G NRL OPTN 23956131 intact exp G AKAP6 OPTN 23414517 intact exp G G G G G G G GP G G G G G G G G G G G G G G G GP G G G GP G RTN3 OPTN 20195357 intact exp G G G G G GP G GP GP G G G G G G G GP G G G G G G GP G G G G G TBC1D15 OPTN 25416956 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G OPTN ZMAT2 20195357 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G G GP GP GP GP GP GP GP G CDKN1A OPTN 19609363 biogrid exp GP GP G G GP G G G GP G G G GP G G GP G G G G GP G G G GP G G GP G MPP1 OPTN 21903422 innatedb,biogrid,intact exp G GP G G GP GP G G GP G GP G GP G G GP GP G GP G GP GP GP G GP G G GP G ZNF181 OPTN 23414517 intact exp P P P P P P P P P P P P P P P P P P P P TFRC OPTN 20161783,20085643,20634958,23357852 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G G GP G GP GP G OPTN SNX6 23414517 intact exp GP G G G G G G GP GP G GP G GP GP G GP G G G G G GP GP GP GP G GP GP G DZIP1 OPTN 23414517 intact exp GP GP G P GP G GP GP G GP GP G GP G GP GP G GP G P G GP P GP P GP GP G RAB25 OPTN 24056041 biogrid exp GP P P P GP GP P GP P G GP P GP G GP GP GP P GP P GP P G OPTN EIF5A2 21903422 innatedb,biogrid,intact exp GP P G P GP G GP P G P P P P P GP P P G P P P P GP P GP GP G ZNF384 OPTN 21903422 innatedb,biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G EIF4G2 OPTN 20195357 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G GABARAP OPTN 21617041 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DYSF OPTN 23414517 intact exp G G G G GP G G GP GP G GP G G G G G G G G G GP G G GP G GP G GP G TNIP1 OPTN 25416956,21988832,23414517,21516116 biogrid,mint,intact exp GP G G G G GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP GP GP GP G OPTN GABARAPL1 21617041 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G G G GP G GP GP GP G GP GP G DAZAP2 OPTN 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G OPTN TBC1D17 22854040,16189514 hprd,biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GRM1 OPTN 16091361 biogrid exp P G P GP G P G GP P P P GP P P P P P P P P GNAS OPTN 20195357 intact exp GNAS OPTN 20195357 biogrid exp G G G G G G G G GP G G G G G G GP G G GP G G G G G GP G G G G DST OPTN 23414517 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G G G G G GP GP GP G GP GP G YWHAB OPTN 21903422 innatedb,biogrid,intact exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G OPTN MYO6 15837803,20161783 biogrid exp GP GP G GP G G GP G GP GP GP G G GP GP G GP G GP GP GP P GP G GP GP SLMAP OPTN 23414517 intact exp G GP G G GP GP G GP GP G G G G GP G GP GP GP GP G GP G GP GP GP G GP GP G OPTN ZNF302 23414517 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G OPTN CDC23 25416956,21516116 biogrid,mint,intact exp GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SOD1 OPTN 23178947 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G OPTN EBNA1BP2 20195357 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PIAS4 OPTN 21988832 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G FAM178A OPTN 20195357 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HSPB1 OPTN 25277244 biogrid,intact exp GP GP G G GP G G GP GP G GP GP GP G G GP G GP GP G GP GP GP GP GP G GP GP G FTH1 OPTN 23414517 intact exp GP G G G GP GP G G GP G GP GP GP G G GP GP G GP G GP GP G G GP GP GP GP G TTN OPTN 23414517 intact exp GP GP G G GP GP G GP GP G P G G GP G GP GP G G G P G G GP GP G G G G OPTN SYNGAP1 20195357 intact exp G GP G GP G GP GP G G G P G G G GP G G GP GP G G GP G G OPTN MPP6 21903422 innatedb,biogrid,intact exp P P G P P P P P GP P P P P GP RAB10 OPTN 25416956 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PARK2 OPTN 25294927 biogrid exp P GP G P GP G GP GP G GP P P G P GP GP P G P GP GP GP P GP G KANSL1L OPTN 23414517 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBB OPTN 23414517 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G STX12 OPTN 26186194 biogrid exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP G GP GP G CMYA5 OPTN 23414517 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G NDUFAF2 OPTN 20195357 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G YWHAH OPTN 21903422 innatedb,biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP GP GP GP G KCTD17 OPTN 21903422 innatedb,biogrid,intact exp P G P GP G P P G P P P P GP P P G P P P P GP VCP OPTN 23414517 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TAX1BP1 OPTN 19609363 biogrid exp GP GP G G GP GP G GP GP G GP G G GP G G GP GP G G GP G GP GP G G GP GP G OPTN OPTN 25416956,20161783,24983867,23414517 biogrid,intact exp, ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SQSTM1 OPTN 25026213 biogrid,intact exp, ortho GP GP G G GP G G G GP G GP GP GP GP G GP G GP GP G GP GP GP GP GP GP GP GP G UBC OPTN 21408173,21617041,19285159,23178947,21862579,18212736,23414517,17702576 innatedb,biogrid,intact exp, ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RAB11A OPTN 24056041,17626244,16905101 biogrid exp, ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HACE1 OPTN 25026213 biogrid,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G FOS OPTN 15867431, 25402006, 21836163 hprd exp, ortho, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP GP GP GP G RIPK1 OPTN 21408173,22675546,17702576, 25402006 innatedb,biogrid exp, ortho, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G OPTN TBK1 21903422,20174559,23414517,18307994, 25402006, 21836163 innatedb,biogrid,mint,intact exp, ortho, pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TNFRSF1A OPTN 22675546, 25402006 biogrid exp, ortho, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RAB11B OPTN 24056041,11495908, 21836163 hprd,biogrid,bci exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CALM1, CALM2, CALM3 OPTN 15840729, 25402006 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRADD OPTN 17702576, 25402006 innatedb,biogrid exp, pred GP GP G G GP GP G G GP G GP G GP GP G G GP G G G GP GP GP G G GP GP GP G HSPA9 OPTN 20195357, 25402006 intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RAB8A OPTN 20388642,20161783,11137014,22854040,20085643,20634958,23357852, 21836163 hprd,biogrid,i2d,intact,bci exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ZDHHC17 OPTN 24705354, 25402006 biogrid,intact exp, pred G GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G GTF3A OPTN 10756201, 21836163 hprd,bci exp, pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HTT OPTN 11137014,23275563,9700202,17500595, 25402006 hprd,biogrid,mint,intact,bci exp, pred GP GP G G GP GP G G GP G P GP P GP G GP GP GP P G GP GP GP G GP GP GP GP OPTN RNF11 15231748, 25402006 hprd,biogrid,i2d,mint,intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRAF3 OPTN 20174559, 25402006 innatedb,biogrid exp, pred G GP G G GP GP G G G G GP GP GP GP G GP GP GP GP G GP G GP G GP G GP GP G OPTN SEMA4A ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G IKBKB OPTN 25402006 ortho, pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G TBKBP1 OPTN 25402006 pred G G G P GP G P GP G GP P GP G GP GP G P GP G GP GP TUBB4A OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP GP GP GP GP G GP P GP GP GP GP GP GP G RCN2 OPTN 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP GP G OPTN NAPG 23023127 pred G GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP G GP GP GP GP GP G HSP90AB1 OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CA11 OPTN 25402006 pred GP G G G GP GP G G GP G GP G G G G GP GP G GP G GP GP G G GP GP GP GP G HAP1 OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G CNST OPTN 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G TUBB OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MTSS1 OPTN 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G HSPA1L OPTN 25402006 pred GP P G G G G G G G G P G G G G GP G TRAF3IP2 OPTN 25402006 pred GP GP P P G P GP GP GP GP GP G GP P GP GP G GP GP GP P GP GP GP P G ZMYND11 OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G OPTN MYOC 21836163 pred G G G G G G GP GP G G GP G GP G G GP G GP G GP G GP GP GP G OPTN VCPIP1 23023127 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G PLEKHM2 OPTN 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CYP1B1 OPTN 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HSP90AA1 OPTN 25402006 pred GP GP G G G GP G G GP G G G G G G G GP G G G GP G G G G G G GP G OPTN AZI2 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CD27 OPTN 25402006 pred G G G GP G G G G G G GP G G G G G G G G G G GP G G HSPA5 OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G OPTN RNF216 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM38 OPTN 25402006 pred GP GP G GP P G GP GP GP GP GP GP G GP GP GP GP GP GP GP GP GP GP GP P G TNFRSF9 OPTN 25402006 pred GP G G G GP G GP GP P G P G GP G GP G P GP GP GP GP G PRPF40B OPTN 25402006 pred P P P P P P P P P P P P P P P P P P P P REL OPTN 25402006 pred GP G G G GP GP G G GP G GP G GP GP G GP GP GP GP G P GP GP G GP GP GP GP G UBE2K OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PFN2 OPTN 25402006 pred GP GP G G G GP G GP GP G GP G GP G G GP GP GP GP G G GP GP GP GP G GP GP G RPS5 OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G OPTN GPRASP2 25402006 pred P P P P P P P P P P P P P P OPTN MAP3K14 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CFLAR OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G NFKBIA OPTN 25402006 pred G GP G G GP GP G GP GP G G G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G YWHAE OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G WDFY3 OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRAF1 OPTN 25402006 pred G G G G GP GP G G GP G GP G G GP G G GP G G G G G G G GP G G G SLC25A5 OPTN 25402006 pred G GP G G GP GP G G G G GP GP G G G GP GP G GP G G G GP G GP G GP GP G BIRC3 OPTN 25402006 pred GP G GP G G GP P GP G GP G GP G GP P G GP GP GP GP GP CAD OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G P GP GP GP GP G STEAP2 OPTN 23023127 pred GP GP G P GP G GP GP G GP P GP P G GP GP GP P G GP GP GP P GP GP GP P G TRIP10 OPTN 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G WDR36 OPTN 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G CDC37 OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G IKBKE OPTN 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G IFI16 OPTN 25402006 pred G G G G GP GP G G GP G GP G G GP G G GP GP G G G G G G G GP G G G CREBBP OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G OPTN LACRT 23023127 pred G MAP3K7 OPTN 25402006 pred GP GP G G G GP G G GP G G GP GP G G G GP G GP G GP GP G G G G GP GP G ACTG1 OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G OPTN C16orf70 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G PACS1 OPTN 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G OPTN IKBKG 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TANK OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PKDCC OPTN 23023127 pred GP GP G G GP GP G G GP G GP G GP G G G GP G GP G GP G G GP G G GP GP G CRMP1 OPTN 25402006 pred G G G G G GP G G G G G G G G G GP GP G G G G G GP G GP G G G G TICAM1 OPTN 25402006 pred GP GP G P G GP GP GP GP GP GP G GP P GP GP GP GP GP GP GP GP GP P G BIRC2 OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP G GP GP GP GP GP GP G CBS OPTN 25402006 pred G G G G G GP G G G G G GP G G G G GP G GP G G G G G G G G G G RIPK2 OPTN 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP G G GP G SYTL4 OPTN 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G P GP GP GP G GP GP GP GP G GP GP G OPTN TNFRSF11A 25402006 pred GP P G GP P P GP P P GP G GP P P G P G G P GP GP P G OPTN HYPK 25402006 pred G G G G G GP G G GP G G G GP GP G GP GP G G G GP G G G GP G G GP G OPTN SETD2 25402006 pred GP GP G G G GP G G GP G GP G GP GP G GP GP GP GP G GP G G GP GP G GP GP G OPTN OTUD5 25402006 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G TRAF5 OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G OCRL OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TNFAIP3 OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G OPTN RIPK3 25402006 pred GP P G GP P GP GP G P P GP GP G GP P P GP G GP GP GP GP GP GP GP P TUBA3C, TUBA3D OPTN 25402006 pred P P P P P P P P P P P P P P ZXDB OPTN 21836163 pred GP G G G G GP G GP GP G GP GP G G GP GP G P G GP GP GP GP GP G GP P G HSPA8 OPTN 25402006 pred P P P P P P P P P P P P P P P P OPTN MAP3K3 25402006 pred G G G G GP GP G GP G G GP G GP GP G GP GP G G G GP G G G GP GP GP G G OPTN RAB3IP 25402006 pred GP G G G G G G G GP G GP GP GP G G GP G P GP G GP GP GP G GP G GP G G ECH1 OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CRADD OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP G GP GP G GP GP G MAP4K2 OPTN 25402006 pred P P P P P P P P P P P P P P P P P P P P P P FADD OPTN 25402006 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP G GP GP GP GP GP GP G LDHB OPTN 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP GP GP G GP GP G GP G GP GP GP G RABIF OPTN 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRAF2 OPTN 25402006 pred P P P P P P P P P P P P P P P P P P P GP GP P

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q96CV9 two hybrid 11137014 association C 3 Q96CV9 affinity chromatography technology 11137014 association C 3 Q96CV9 Q29122 electron microscopy 19805065 direct interaction X 2 Q96CV9 Q29122 surface plasmon resonance 19805065 direct interaction X 2 Q96CV9 Q29122 anti tag coimmunoprecipitation 19805065 direct interaction X 2 Q96CV9 P61007 pull down 11137014 direct interaction X 2 Q96CV9 P61007 two hybrid 11137014 physical association X 2 Q96CV9 Q9Y3C5 two hybrid 15231748 physical association X 2 Q96CV9 P0CK53 two hybrid 17446270 physical association X 2 Q96CV9 P38646 display technology 20195357 physical association X 2 Q96CV9 P78344 display technology 20195357 physical association X 2 Q96CV9 O95197 display technology 20195357 physical association X 2 Q96CV9 Q6IB29 display technology 20195357 physical association X 2 Q96CV9 Q15018 display technology 20195357 physical association X 2 Q96CV9 Q9UJX2 two hybrid 21516116 physical association X 2 Q96CV9 Q00013 anti tag coimmunoprecipitation 21903422 physical association X 2 Q96CV9 Q13023 two hybrid fragment pooling approach 23414517 physical association X 2 Q96CV9 Q00610 two hybrid fragment pooling approach 23414517 physical association X 2 Q96CV9 A0A024R525 two hybrid fragment pooling approach 23414517 physical association X 2 Q96CV9 Q96CV9 two hybrid fragment pooling approach 23414517 physical association X 2 Q96CV9 Q96CV9 two hybrid fragment pooling approach 23414517 physical association X 2 Q96CV9 P55072 two hybrid fragment pooling approach 23414517 physical association X 2 Q96CV9 P04275 two hybrid fragment pooling approach 23414517 physical association X 2 Q96CV9 P04275 proximity ligation assay 23414517 physical association X 2 Q96CV9 Q13023 proximity ligation assay 23414517 physical association X 2 Q96CV9 Q99IB8 two hybrid 24136289 physical association X 2 Q96CV9 Q99IB8 two hybrid 24136289 physical association X 2 Q96CV9 Q99IB8 split firefly luciferase complementation 24136289 physical association X 2 Q96CV9 Q13501 anti tag coimmunoprecipitation 25026213 physical association X 2 Q96CV9 Q13501 anti tag coimmunoprecipitation 25026213 physical association X 2 Q96CV9 Q13501 anti tag coimmunoprecipitation 25026213 physical association X 2 Q96CV9 Q13501 anti tag coimmunoprecipitation 25026213 physical association X 2 Q96CV9 Q96CV9 two hybrid array 25416956 physical association X 2 Q96CV9 P61026 two hybrid prey pooling approach 25416956 physical association X 2 Q96CV9 A0A024R4Q4 two hybrid prey pooling approach 25416956 physical association X 2 Q96CV9 Q9UJX2 two hybrid prey pooling approach 25416956 physical association X 2 Q96CV9 P61026 two hybrid array 25416956 physical association X 2 Q96CV9 A0A024R4Q4 two hybrid array 25416956 physical association X 2 Q96CV9 Q9UJX2 two hybrid array 25416956 physical association X 2 Q96CV9 A0A024R4Q4 validated two hybrid 25416956 physical association X 2 Q96CV9 P61026 validated two hybrid 25416956 physical association X 2 Q96CV9 Q9UJX2 validated two hybrid 25416956 physical association X 2 Q96CV9 anti tag coimmunoprecipitation 21903422 association C 12 Q96CV9 anti tag coimmunoprecipitation 25026213 association C 3 Q96CV9 anti bait coimmunoprecipitation 25026213 association C 3 Q96CV9 anti tag coimmunoprecipitation 22854040 association C 3 Q9HA65 Q96CV9 two hybrid pooling approach 16189514 physical association X 2 Q9HA65 Q96CV9 confocal microscopy 22854040 colocalization X 2 Q9HA65 Q96CV9 two hybrid 22854040 physical association X 2 Q9HA65 Q96CV9 pull down 22854040 physical association X 2 Q9HA65 Q96CV9 anti bait coimmunoprecipitation 22854040 physical association X 2 Q9HA65 Q96CV9 anti tag coimmunoprecipitation 22854040 physical association X 2 Q9NR11 Q96CV9 two hybrid fragment pooling approach 23414517 physical association X 2 A0A024R110 Q96CV9 two hybrid prey pooling approach 25416956 physical association X 2 A0A024R110 Q96CV9 two hybrid array 25416956 physical association X 2 A0A024R110 Q96CV9 validated two hybrid 25416956 physical association X 2 Q15884 Q96CV9 two hybrid 21516116 physical association X 2 P0CG48 Q96CV9 two hybrid fragment pooling approach 23414517 physical association X 2 P11055 Q96CV9 two hybrid fragment pooling approach 23414517 physical association X 2 Q8IUH5 Q96CV9 anti tag coimmunoprecipitation 24705354 physical association X 2 Q96CV9 anti tag coimmunoprecipitation 19615732 physical association C 13 Q96CV9 P42858 pull down 11137014 direct interaction X 2 Q96CV9 P42858 two hybrid 11137014 physical association X 2 Q96CV9 Q9Y3C0 two hybrid pooling approach 16189514 physical association X 2 Q96CV9 P42858 two hybrid 17500595 physical association X 2 Q96CV9 P42858 two hybrid 17500595 physical association X 2 Q96CV9 P42858 two hybrid 17500595 physical association X 2 Q96CV9 P42858 two hybrid 17500595 physical association X 2 Q96CV9 P42858 two hybrid 17500595 physical association X 2 Q96CV9 P42858 two hybrid 17500595 physical association X 2 Q96CV9 O14949 display technology 20195357 physical association X 2 Q96CV9 Q8IX21 display technology 20195357 physical association X 2 Q96CV9 P84996 display technology 20195357 physical association X 2 Q96CV9 Q9UPN3-2 display technology 20195357 physical association X 2 Q96CV9 Q96NC0 display technology 20195357 physical association X 2 Q96CV9 Q8N183 display technology 20195357 physical association X 2 Q96CV9 P37231 display technology 20195357 physical association X 2 Q96CV9 A0A024R7I3 bimolecular fluorescence complementation 20388642 physical association X 2 Q96CV9 A0A024R7I3 confocal microscopy 20388642 physical association X 2 Q96CV9 Q8N448 two hybrid 21516116 physical association X 2 Q96CV9 Q9Y3C0 two hybrid 21516116 physical association X 2 Q96CV9 A0A024R7I3 confocal microscopy 22854040 colocalization X 2 Q96CV9 A0A024R7I3 two hybrid 22854040 physical association X 2 Q96CV9 P42858 two hybrid prey pooling approach 23275563 physical association X 2 Q96CV9 P20929-4 two hybrid fragment pooling approach 23414517 physical association X 2 Q96CV9 P20929-4 two hybrid fragment pooling approach 23414517 physical association X 2 Q96CV9 Q14BN4 two hybrid fragment pooling approach 23414517 physical association X 2 Q96CV9 Q9UNH7 two hybrid fragment pooling approach 23414517 physical association X 2 Q96CV9 Q8WZ42 two hybrid fragment pooling approach 23414517 physical association X 2 Q96CV9 P0CG47 two hybrid fragment pooling approach 23414517 physical association X 2 Q96CV9 P0CG47 two hybrid fragment pooling approach 23414517 physical association X 2 Q96CV9 Q2M3W8 two hybrid fragment pooling approach 23414517 physical association X 2 Q96CV9 A0A024R7D7 two hybrid fragment pooling approach 23414517 physical association X 2 Q96CV9 P20929 proximity ligation assay 23414517 physical association X 2 Q96CV9 Q14BN4 proximity ligation assay 23414517 physical association X 2 Q96CV9 Q9UNH7 proximity ligation assay 23414517 physical association X 2 Q96CV9 Q8WZ42 proximity ligation assay 23414517 physical association X 2 Q96CV9 P54845 fluorescence microscopy 23956131 colocalization X 2 Q96CV9 P54845 proximity ligation assay 23956131 physical association X 2 Q96CV9 P54845 fluorescence microscopy 23956131 colocalization X 2 Q96CV9 P54845 anti tag coimmunoprecipitation 23956131 physical association X 2 Q96CV9 P54845 anti tag coimmunoprecipitation 23956131 physical association X 2 Q96CV9 P54845 anti bait coimmunoprecipitation 23956131 physical association X 2 Q96CV9 Q8IYU2 pull down 25026213 physical association X 2 Q96CV9 Q658J6 pull down 25026213 physical association X 2 Q96CV9 Q8IYU2 two hybrid 25026213 physical association X 2 Q96CV9 Q8IYU2 two hybrid 25026213 physical association X 2 Q96CV9 Q8IYU2 anti bait coimmunoprecipitation 25026213 physical association X 2 Q96CV9 Q8IYU2 two hybrid 25026213 physical association X 2 Q96CV9 Q8IYU2 anti tag coimmunoprecipitation 25026213 physical association X 2 Q96CV9 Q8IYU2 anti tag coimmunoprecipitation 25026213 physical association X 2 Q96CV9 Q8IYU2 fluorescence microscopy 25026213 colocalization X 2 Q96CV9 Q8IYU2 pull down 25026213 physical association X 2 Q96CV9 Q8IYU2 pull down 25026213 physical association X 2 Q96CV9 P04792 reverse ras recruitment system 25277244 physical association X 2 Q96CV9 A0A090N7S8 two hybrid prey pooling approach 25416956 physical association X 2 Q96CV9 Q9Y3C0 two hybrid prey pooling approach 25416956 physical association X 2 Q96CV9 Q9BS34 two hybrid prey pooling approach 25416956 physical association X 2 Q96CV9 Q9Y3C0 two hybrid prey pooling approach 25416956 physical association X 2 Q96CV9 Q9BS34 two hybrid array 25416956 physical association X 2 Q96CV9 A0A090N7S8 two hybrid array 25416956 physical association X 2 Q96CV9 Q9Y3C0 two hybrid array 25416956 physical association X 2 Q96CV9 Q9Y3C0 two hybrid array 25416956 physical association X 2 Q96CV9 Q9BS34 validated two hybrid 25416956 physical association X 2 Q96CV9 Q9Y3C0 validated two hybrid 25416956 physical association X 2 Q96CV9 A0A090N7S8 validated two hybrid 25416956 physical association X 2 Q03001 Q96CV9 two hybrid fragment pooling approach 23414517 physical association X 2 Q03001 Q96CV9 proximity ligation assay 23414517 physical association X 2 Q96CV9 anti tag coimmunoprecipitation 25026213 association C 3 O75923 Q96CV9 proximity ligation assay 23414517 physical association X 2 O75923 Q96CV9 confocal microscopy 23414517 colocalization X 2 O75923 Q96CV9 two hybrid fragment pooling approach 23414517 physical association X 2 Q8TC07 Q96CV9 two hybrid prey pooling approach 25416956 physical association X 2 Q8TC07 Q96CV9 two hybrid array 25416956 physical association X 2 Q8TC07 Q96CV9 validated two hybrid 25416956 physical association X 2 P61513 Q96CV9 display technology 20195357 physical association X 2 Q86YF9 Q96CV9 two hybrid fragment pooling approach 23414517 physical association X 2 Q9UHD2 Q96CV9 pull down 18307994 physical association X 2 Q9UHD2 Q96CV9 pull down 18307994 physical association X 2 Q9UHD2 Q96CV9 anti tag coimmunoprecipitation 18307994 physical association X 2 Q9UHD2 Q96CV9 anti tag coimmunoprecipitation 18307994 physical association X 2 Q9UHD2 Q96CV9 anti tag coimmunoprecipitation 18307994 physical association X 2 Q9UHD2 Q96CV9 pull down 18307994 physical association X 2 Q9UHD2 Q96CV9 pull down 18307994 physical association X 2 Q9UHD2 Q96CV9 pull down 18307994 physical association X 2 Q9UHD2 Q96CV9 two hybrid fragment pooling approach 23414517 physical association X 2 Q96PV0 Q96CV9 display technology 20195357 physical association X 2 P07199 Q96CV9 display technology 20195357 physical association X 2 Q15025 Q96CV9 two hybrid 21516116 physical association X 2 Q15025 Q96CV9 two hybrid fragment pooling approach 23414517 physical association X 2 Q15025 Q96CV9 two hybrid prey pooling approach 25416956 physical association X 2 Q15025 Q96CV9 two hybrid array 25416956 physical association X 2 Q15025 Q96CV9 validated two hybrid 25416956 physical association X 2 A0AUZ9 Q96CV9 two hybrid fragment pooling approach 23414517 physical association X 2 Q8N3K9 Q96CV9 two hybrid fragment pooling approach 23414517 physical association X 2 Q9Y462 Q96CV9 two hybrid fragment pooling approach 23414517 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B DST OPTN MI:0663(confocal microscopy)|MI:0663(confocal microscopy) 23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_127266|UniProt_126719 prey|neutral component bait|neutral component CDKN1A OPTN MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 19609363 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_147990|BIOGRID_147991|BIOGRID_147992 bait|bait|prey prey|prey|bait RPL37A OPTN MI:0034(display technology) 20195357 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_105170 prey bait GNAS OPTN MI:0034(display technology) 20195357 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_105171 prey bait ZNF384 OPTN MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 21903422 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0915(physical association) (intact)|(intact)|(biogrid) UniProt_115775|UniProt_172517|BIOGRID_155678 prey|prey|prey bait|bait|bait AKAP6 OPTN MI:0663(confocal microscopy)|MI:0663(confocal microscopy) 23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_127262|UniProt_126723 prey|neutral component bait|neutral component YWHAB OPTN MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 21903422 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association)|MI:0914(association) (biogrid)|(intact)|(intact) BIOGRID_155673|UniProt_115775|UniProt_172517 prey|prey|prey bait|bait|bait FLII OPTN MI:0018(two hybrid) 10366446 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_6863 - - FOS OPTN MI:0492(in vitro) 15867431 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_32998 - - YWHAG OPTN MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 21903422 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association)|MI:0914(association) (biogrid)|(intact)|(intact) BIOGRID_155674|UniProt_115775|UniProt_172517 prey|prey|prey bait|bait|bait CALM1 OPTN MI:0096(pull down) 15840729 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_153788 bait prey FAM189A2 OPTN MI:0018(two hybrid) 21516116 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_114314 bait prey EPS15 OPTN MI:0428(imaging technique) 17626244 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_285178 prey bait FAM178A OPTN MI:0034(display technology)|MI:0096(pull down) 20195357 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_105168|BIOGRID_290401 prey|prey bait|bait GABARAPL2 OPTN MI:0018(two hybrid) 21617041 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_197225 bait prey YWHAQ OPTN MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 21903422 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association)|MI:0914(association) (biogrid)|(intact)|(intact) BIOGRID_155676|UniProt_115775|UniProt_172517 prey|prey|prey bait|bait|bait LNX2 OPTN MI:0018(two hybrid) 21516116 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_114397 prey bait DYSF OPTN MI:0663(confocal microscopy)|MI:0663(confocal microscopy)|MI:0663(confocal microscopy) 23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association) (intact)|(intact)|(intact) UniProt_127004|UniProt_126711|UniProt_126726 bait|neutral component|neutral component prey|neutral component|neutral component EIF4G2 OPTN MI:0034(display technology) 20195357 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_104576 prey bait RAB11B OPTN MI:0493(in vivo) 11495908 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_10834 - - SOD1 OPTN MI:0004(affinity chromatography technology) 23178947 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_248264 bait prey RAB4A OPTN MI:0004(affinity chromatography technology) 20634958 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_216028 prey bait MYH3 OPTN MI:0663(confocal microscopy) 23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_127269 prey bait MPP1 OPTN MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 21903422 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact)|(intact)|(biogrid)|(intact) BIOGRID_155957|UniProt_115775|UniProt_172517|UniProt_115865|BIOGRID_155670|UniProt_172601 prey|prey|prey|bait|prey|bait bait|bait|bait|prey|bait|prey KCTD17 OPTN MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 21903422 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association)|MI:0914(association) (biogrid)|(intact)|(intact) BIOGRID_155669|UniProt_115775|UniProt_172517 prey|prey|prey bait|bait|bait SLMAP OPTN MI:0663(confocal microscopy)|MI:0663(confocal microscopy) 23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_127274|UniProt_126737 prey|neutral component bait|neutral component FAM175B OPTN MI:0034(display technology) 20195357 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_104585 prey bait VCP OPTN MI:0663(confocal microscopy) 23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_127282 prey bait OPTN MAP1LC3A MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21617041 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_197215|BIOGRID_197226|BIOGRID_197247 prey|prey|bait bait|bait|prey TNIP1 OPTN MI:0018(two hybrid)|MI:0397(two hybrid array)|MI:0004(affinity chromatography technology)|MI:0663(confocal microscopy) 21516116,21988832,23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(intact)|(biogrid)|(intact) UniProt_114399|UniProt_119983|BIOGRID_285798|UniProt_127277 prey|unspecified role|prey|prey bait|unspecified role|bait|bait TNF OPTN MI:0004(affinity chromatography technology) 22675546 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_260080 bait prey TNFRSF1A OPTN MI:0004(affinity chromatography technology) 22675546 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_260077 prey bait OPTN GABARAPL1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21617041 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_197224|BIOGRID_197214|BIOGRID_197235 prey|prey|prey bait|bait|bait TRADD OPTN MI:0096(pull down) 17702576 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_222860 prey bait VWF OPTN MI:0663(confocal microscopy)|MI:0663(confocal microscopy) 23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_127283|UniProt_126734 prey|neutral component bait|neutral component OPTN EIF5A2 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 21903422 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0915(physical association) (intact)|(intact)|(biogrid) UniProt_115775|UniProt_172517|BIOGRID_155668 bait|bait|bait prey|prey|prey OPTN MAP1LC3B MI:0018(two hybrid)|MI:0096(pull down)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down) 21617041,23805866 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_197238|BIOGRID_283210|BIOGRID_283211|BIOGRID_197227|BIOGRID_197231|BIOGRID_283209 prey|prey|bait|prey|prey|prey bait|bait|prey|bait|bait|bait ZNF181 OPTN MI:0663(confocal microscopy) 23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_127284 prey bait GTF3A OPTN MI:0492(in vitro) 10756201 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_7892 - - OPTN TBC1D17 MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|- (intact)|(biogrid)|MI:0471(mint)|MI:0471(mint)|MI:0468(hprd) UniProt_153902|BIOGRID_81077|MINT_69534|MINT_40161|HPRD_21979 unspecified role|bait|bait|bait|- unspecified role|prey|prey|prey|- OPTN ZNF711 MI:0663(confocal microscopy) 23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_127287 bait prey OPTN CCDC53 MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 16189514,21516116 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|-|MI:0915(physical association) (intact)|MI:0471(mint)|MI:0471(mint)|(biogrid)|MI:0468(hprd)|(intact) UniProt_152937|MINT_38483|MINT_67692|BIOGRID_80094|HPRD_21977|UniProt_114400 unspecified role|bait|bait|bait|-|bait unspecified role|prey|prey|prey|-|prey OPTN RNF11 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15231748 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|-|MI:0915(physical association) MI:0471(mint)|MI:0471(mint)|(biogrid)|MI:0468(hprd)|(intact) MINT_60198|MINT_31433|BIOGRID_259431|HPRD_37477|UniProt_78522 prey|prey|prey|-|prey bait|bait|bait|-|bait HTT OPTN MI:0018(two hybrid)|MI:0096(pull down)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|-|MI:0018(two hybrid) 11137014,17500595,23275563,9700202 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|-|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact)|MI:0468(hprd)|(biogrid)|(biogrid)|(intact)|(intact)|(biogrid)|(intact)|(biogrid)|(intact)|(intact)|(intact)|(intact) BIOGRID_251039|UniProt_69446|UniProt_69448|HPRD_35899|BIOGRID_116539|BIOGRID_116544|UniProt_90754|UniProt_90728|BIOGRID_90538|UniProt_90780|BIOGRID_116542|UniProt_90821|UniProt_90834|UniProt_126497|UniProt_90699 bait|prey|prey|-|prey|prey|bait|bait|bait|bait|prey|bait|bait|bait|bait prey|bait|bait|-|bait|bait|prey|prey|prey|prey|bait|prey|prey|prey|prey CLTC OPTN MI:0663(confocal microscopy) 23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_127264 prey bait OPTN KANSL1L MI:0663(confocal microscopy) 23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_127263 bait prey NEB OPTN MI:0663(confocal microscopy)|MI:0663(confocal microscopy)|MI:0663(confocal microscopy) 23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact) UniProt_127271|UniProt_127270|UniProt_126738 prey|prey|neutral component bait|bait|neutral component GNAS OPTN MI:0096(pull down) 20195357 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_290402 prey bait UQCRQ OPTN MI:0034(display technology)|MI:0096(pull down) 20195357 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_105165|BIOGRID_290400 prey|prey bait|bait YWHAZ OPTN MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 21903422 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association)|MI:0914(association) (biogrid)|(intact)|(intact) BIOGRID_155677|UniProt_115775|UniProt_172517 prey|prey|prey bait|bait|bait RIPK1 OPTN MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0096(pull down) 17702576,21408173,22675546 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_260078|BIOGRID_143495|BIOGRID_222858|BIOGRID_222857 prey|prey|prey|prey bait|bait|bait|bait TFRC OPTN MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20085643,20161783,20634958,23357852 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_216029|BIOGRID_289647|BIOGRID_196832|BIOGRID_196834|BIOGRID_216229 prey|prey|prey|bait|prey bait|bait|bait|prey|bait TAX1BP1 OPTN MI:0018(two hybrid)|MI:0018(two hybrid) 19609363 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_147998|BIOGRID_147997 prey|bait bait|prey GRM1 OPTN MI:0018(two hybrid)|MI:0018(two hybrid) 16091361 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_216381|BIOGRID_216382 bait|bait prey|prey YWHAH OPTN MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 21903422 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association)|MI:0914(association) (biogrid)|(intact)|(intact) BIOGRID_155675|UniProt_115775|UniProt_172517 prey|prey|prey bait|bait|bait OPTN SYNGAP1 MI:0034(display technology) 20195357 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_104580 bait prey PIAS4 OPTN MI:0397(two hybrid array)|MI:0004(affinity chromatography technology) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_119984|BIOGRID_285799 unspecified role|prey unspecified role|bait OPTN ZMAT2 MI:0034(display technology) 20195357 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_104574 bait prey ZDHHC17 OPTN MI:0397(two hybrid array)|MI:0397(two hybrid array)|MI:0397(two hybrid array)|MI:0397(two hybrid array)|MI:0397(two hybrid array) 24705354 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(intact) UniProt_133439|UniProt_133461|UniProt_176670|UniProt_133391|UniProt_176622 prey|bait|prey|bait|bait bait|null|bait|null|null FTH1 OPTN MI:0663(confocal microscopy) 23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_127268 prey bait OPTN MPP6 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 21903422 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0915(physical association) (intact)|(intact)|(biogrid) UniProt_115775|UniProt_172517|BIOGRID_155671 bait|bait|bait prey|prey|prey OPTN BRE MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_301612 prey bait UBB OPTN MI:0663(confocal microscopy)|MI:0663(confocal microscopy)|MI:0428(imaging technique) 22101367,23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization) (intact)|(intact)|(biogrid) UniProt_127280|UniProt_127279|BIOGRID_196277 prey|prey|prey bait|bait|bait UBC OPTN MI:0018(two hybrid)|MI:0096(pull down)|MI:0663(confocal microscopy)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17702576,19285159,19820708,20085643,21059646,21139048,21408173,21617041,21862579,21890473,21906983,21963094,23000965,23178947,23414517,23732909 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_197254|BIOGRID_222855|UniProt_127281|BIOGRID_175815|BIOGRID_222853|BIOGRID_190235|BIOGRID_269346|BIOGRID_180109|BIOGRID_248265|BIOGRID_143921|BIOGRID_200646|BIOGRID_170885|BIOGRID_197228|BIOGRID_143494|BIOGRID_281381|BIOGRID_166511|BIOGRID_196833|BIOGRID_197838 prey|prey|prey|bait|bait|prey|bait|bait|bait|bait|bait|bait|bait|bait|prey|bait|prey|prey bait|bait|bait|prey|prey|bait|prey|prey|prey|prey|prey|prey|prey|prey|bait|prey|bait|bait OPTN CYLD MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21408173 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_143491|BIOGRID_143493|BIOGRID_143492 bait|bait|prey prey|prey|bait OPTN ZNF302 MI:0663(confocal microscopy) 23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_127285 bait prey CNTN2 OPTN MI:0018(two hybrid)|MI:0018(two hybrid) 19609363 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_147993|BIOGRID_147996 prey|bait bait|prey TRAF3 OPTN MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20174559 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_199123|BIOGRID_199124 prey|bait bait|prey WDR20 OPTN MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100724|BIOGRID_120132 bait|bait prey|prey PPARG OPTN MI:0034(display technology) 20195357 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_104729 bait prey DZIP1 OPTN MI:0663(confocal microscopy) 23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_127267 prey bait OPTN ZNF426 MI:0663(confocal microscopy) 23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_127286 bait prey RTN3 OPTN MI:0034(display technology) 20195357 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_104578 prey bait CENPB OPTN MI:0034(display technology) 20195357 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_104577 prey bait RAB12 OPTN MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 23357852 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_289648|BIOGRID_289650 bait|bait prey|prey CMYA5 OPTN MI:0663(confocal microscopy) 23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_127265 prey bait OPTN MACF1 MI:0034(display technology) 20195357 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_104573 bait null OPTN TTN MI:0663(confocal microscopy)|MI:0663(confocal microscopy) 23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_127278|UniProt_126724 bait|neutral component prey|neutral component OPTN ASAP1 MI:0018(two hybrid) 18685082 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_207292 bait prey OPTN MYO6 MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid) 15837803,20161783 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_216230|BIOGRID_216228|BIOGRID_216231|BIOGRID_216232 bait|bait|prey|prey prey|prey|bait|bait RAB14 OPTN MI:0047(far western blotting)|MI:0047(far western blotting) 19702578 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_284254|BIOGRID_284257 bait|bait prey|prey OPTN SNX6 MI:0663(confocal microscopy)|MI:0663(confocal microscopy) 23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_126729|UniProt_127275 neutral component|bait neutral component|prey OPTN TBK1 MI:0096(pull down)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0663(confocal microscopy)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 18307994,20174559,21903422,23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association) (intact)|(intact)|(biogrid)|MI:0471(mint)|(intact)|(intact)|(biogrid)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(intact)|MI:0471(mint)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(biogrid)|MI:0471(mint)|(intact)|(intact)|(biogrid)|(biogrid)|MI:0471(mint)|(biogrid)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(biogrid)|(intact)|(intact)|(intact)|(intact)|(intact) UniProt_95675|UniProt_95676|BIOGRID_216219|MINT_35162|UniProt_95678|UniProt_95679|BIOGRID_155993|MINT_64156|MINT_35168|MINT_35165|MINT_35164|UniProt_95674|MINT_64170|UniProt_95673|MINT_64159|MINT_64158|MINT_64157|MINT_64166|MINT_64167|BIOGRID_199120|MINT_64164|UniProt_95681|UniProt_95680|BIOGRID_155672|BIOGRID_199122|MINT_35157|BIOGRID_199121|MINT_35156|MINT_35155|MINT_35154|BIOGRID_216220|BIOGRID_155794|UniProt_127276|UniProt_115788|UniProt_115775|UniProt_172530|UniProt_172517 prey|prey|bait|prey|bait|bait|prey|prey|bait|bait|bait|prey|bait|prey|prey|prey|bait|bait|bait|prey|prey|bait|bait|bait|bait|prey|bait|prey|bait|prey|bait|prey|bait|prey|bait|prey|bait bait|bait|prey|bait|prey|prey|bait|bait|prey|prey|prey|bait|prey|bait|bait|bait|prey|prey|prey|bait|bait|prey|prey|prey|prey|bait|prey|bait|prey|bait|prey|bait|prey|bait|prey|bait|prey OPTN EBNA1BP2 MI:0034(display technology) 20195357 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_104582 bait prey OPTN CDC23 MI:0018(two hybrid) 21516116 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_114398 bait prey GABARAP OPTN MI:0018(two hybrid) 21617041 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_197223 bait prey NDUFAF2 OPTN MI:0034(display technology) 20195357 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_104579 prey bait RAB11A OPTN MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0114(x-ray crystallography) 16905101,17626244 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0403(colocalization)|MI:0914(association) (biogrid)|(biogrid)|(biogrid) BIOGRID_285179|BIOGRID_285146|BIOGRID_288998 prey|bait|bait bait|prey|prey RAB8A OPTN MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology) 11137014,20085643,20161783,20634958,23357852 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd)|(biogrid) BIOGRID_116540|BIOGRID_116541|BIOGRID_116543|BIOGRID_289649|BIOGRID_216227|BIOGRID_216027|HPRD_177|BIOGRID_196836 prey|prey|prey|bait|prey|prey|-|bait bait|bait|bait|prey|bait|bait|-|prey

PPI - HINT Gene A Gene B PMID Method Quality UBC OPTN 21617041,21059646,21862579,23178947,21617041,19285159,27035970,21862579,27035970,20085643,26451915,25969509,19820708,17702576,21408173,21963094,21408173,26365381 0096,0004,0004,0096,0004,0096,0415,0096,0096,0004,0096,0096,0004,0096,0096,0004,0004,0096 LC RAB8A OPTN 22854040,11137014,11137014,20388642,11137014,20161783,20388642,20634958,22854040,20085643,11137014 0018,0018,0428,0663,0096,0004,0809,0004,0663,0004,0004 LC RAB11A OPTN 17626244,24056041,17626244,24056041,24056041 0018,0096,0428,0018,0004 LC RIPK1 OPTN 22675546,17702576,17702576,17702576,21408173 0004,0007,0096,0004,0004 LC DKFZP686P0251 OPTN 19615732 0004 HT DKFZP686O0451 OPTN 20085643,20634958,23357852,20161783 0004,0004,0004,0004 LC STX12 OPTN 26186194 0004 HT RAB3IL1 OPTN 26186194 0004 HT WDR20 OPTN 19615732,19615732 0004,0007 HT OPTN OPTN 24983867,24983867,20161783,24983867,24983867 0813,0055,0004,0004,0007 LC OPTN MAP1LC3B 23805866,21617041,23805866,21617041,23805866,25026213 0096,0096,0004,0428,0114,0096 LC OPTN MAP1LC3A 25026213,21617041,21617041,21617041 0096,0096,0018,0004 LC OPTN CYLD 25923723,25923723,21408173,21408173,21408173 0428,0004,0096,0018,0004 LC OPTN BRE 22863883 0401 HT OPTN TBK1 18307994,25923723,27035970,27035970,27035970,21903422,21903422,26365381,25803835,25923723,20174559,26365381,18307994,18307994,21903422,20174559,18307994,20174559,25803835 0096,0415,0004,0415,0096,0096,0007,0415,0004,0428,0096,0004,0007,0018,0004,0004,0004,0428,0096 LC OPTN MYO6 26971995,15837803,20161783,15837803,15837803 0096,0096,0004,0018,0004 LC DKFZP686P0251 OPTN 19615732 0004 HT STX12 OPTN 26186194 0004 HT RAB3IL1 OPTN 26186194 0004 HT WDR20 OPTN 19615732,19615732 0004,0007 HT OPTN BRE 22863883 0401 HT UBC OPTN 21617041,21059646,21862579,23178947,21617041,19285159,27035970,21862579,27035970,20085643,26451915,25969509,19820708,17702576,21408173,21963094,21408173,26365381 0096,0004,0004,0096,0004,0096,0415,0096,0096,0004,0096,0096,0004,0096,0096,0004,0004,0096 LC RAB8A OPTN 22854040,11137014,11137014,20388642,11137014,20161783,20388642,20634958,22854040,20085643,11137014 0018,0018,0428,0663,0096,0004,0809,0004,0663,0004,0004 LC RAB11A OPTN 17626244,24056041,17626244,24056041,24056041 0018,0096,0428,0018,0004 LC RIPK1 OPTN 22675546,17702576,17702576,17702576,21408173 0004,0007,0096,0004,0004 LC DKFZP686O0451 OPTN 20085643,20634958,23357852,20161783 0004,0004,0004,0004 LC OPTN OPTN 24983867,24983867,20161783,24983867,24983867 0813,0055,0004,0004,0007 LC OPTN MAP1LC3B 23805866,21617041,23805866,21617041,23805866,25026213 0096,0096,0004,0428,0114,0096 LC OPTN MAP1LC3A 25026213,21617041,21617041,21617041 0096,0096,0018,0004 LC OPTN CYLD 25923723,25923723,21408173,21408173,21408173 0428,0004,0096,0018,0004 LC OPTN TBK1 18307994,25923723,27035970,27035970,27035970,21903422,21903422,26365381,25803835,25923723,20174559,26365381,18307994,18307994,21903422,20174559,18307994,20174559,25803835 0096,0415,0004,0415,0096,0096,0007,0415,0004,0428,0096,0004,0007,0018,0004,0004,0004,0428,0096 LC OPTN MYO6 26971995,15837803,20161783,15837803,15837803 0096,0096,0004,0018,0004 LC KANSL1L OPTN 23414517 0399 HT UQCRQ OPTN 20195357,20195357 0034,0096 LC DYSF OPTN 23414517,23414517,23414517 0813,0663,0399 HT RTN3 OPTN 20195357 0034 LC FTH1 OPTN 23414517 0399 HT VWF OPTN 23414517,23414517 0813,0399 HT HSPB1 OPTN 25277244 0097 LC CENPB OPTN 20195357 0034 LC UBB OPTN 23414517 0399 HT UBC OPTN 27035970,27035970,23414517,18212736 0415,0096,0399,0018 LC,HT MYH3 OPTN 23414517 0399 HT NEB OPTN 23414517,23414517 0813,0399 HT PPARG OPTN 20195357 0034 LC HSPA9 OPTN 20195357 0034 LC CDKN1A OPTN 19609363,19609363 0018,0004 LC EPS15 OPTN 17626244 0018 LC HTT OPTN 23275563,9700202,11137014,11137014,17500595,23275563,11137014 1112,0018,0018,0096,0018,0018,0004 HT,LC NRL OPTN 23956131,23956131,23956131,23956131,23956131,23956131 0007,0006,0004,0813,0428,0416 LC VCP OPTN 23414517 0399 HT RAB25 OPTN 24056041,24056041,24056041,24056041,24056041 0114,0018,0428,0004,0096 LC RAB8A OPTN 22854040,23357852,11137014,11137014,20388642,11137014,20388642,22854040,11137014 0018,0018,0018,0428,0663,0096,0809,0663,0004 LC RAB10 OPTN 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT RAB14 OPTN 19702578,19702578 0018,0047 LC RPL37A OPTN 20195357 0034 LC RAB11A OPTN 16905101,17626244,24056041,17626244,24056041,24056041 0114,0018,0096,0428,0018,0004 LC EIF4G2 OPTN 20195357 0034 LC CLTC OPTN 23414517 0399 HT DST OPTN 23414517,23414517 0813,0399 HT AKAP6 OPTN 23414517,23414517 0813,0399 HT FLII OPTN 10366446 0018 LC SLMAP OPTN 23414517,23414517 0813,0399 HT FAM175B OPTN 20195357 0034 LC TNIP1 OPTN 21516116,25416956,25416956,25416956,23414517,21988832,25416956 0018,1112,0397,0018,0399,0018,1356 HT DAZAP2 OPTN 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT FAM189A2 OPTN 21516116 0018 HT RAB11B OPTN 24056041,24056041 0018,0004 LC ZNF181 OPTN 23414517 0399 HT Q59HC2 OPTN 16091361,16091361 0004,0018 LC GNAS OPTN 20195357,20195357 0034,0096 LC RAB12 OPTN 23357852,23357852 0018,0004 LC ZNF329 OPTN 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT DZIP1 OPTN 23414517 0399 HT ZDHHC17 OPTN 24705354,24705354,24705354,24705354,24705354 0397,0018,0007,0004,0729 HT SLF2 OPTN 20195357,20195357 0034,0096 LC HACE1 OPTN 25026213,25026213,25026213,25026213,25026213,25026213,25026213,25026213 0004,0018,0997,0006,0007,0096,0416,0415 LC NDUFAF2 OPTN 20195357 0034 LC PIAS4 OPTN 21988832 0018 HT CMYA5 OPTN 23414517 0399 HT LNX2 OPTN 21516116 0018 HT TBC1D15 OPTN 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT ZNF398 OPTN 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT Q8WU02 OPTN 21516116 0018 HT TTN OPTN 23414517,23414517 0813,0399 HT OPTN OPTN 24983867,24983867,27620379,25416956,25416956,24983867,23414517,24983867 0813,0055,0114,0397,0018,0004,0399,0007 LC,HT OPTN ZMAT2 20195357 0034 LC OPTN SYNGAP1 20195357 0034 LC OPTN EBNA1BP2 20195357 0034 LC OPTN ZNF670 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT OPTN ZNF426 23414517 0399 HT OPTN MAP1LC3C 26451915 0018 LC OPTN MAP1LC3B 23805866,23805866,23805866 0096,0004,0114 LC OPTN GABARAPL1 21617041,21617041,21617041 0096,0018,0004 LC OPTN MAP1LC3A 21617041,21617041,21617041 0096,0018,0004 LC OPTN TBC1D17 22854040,16189514,22854040,22854040,22854040,16189514,22854040,22854040 0018,0398,0006,0007,0096,0018,0663,0004 LC,HT OPTN CYLD 21408173,21408173,21408173 0096,0018,0004 LC OPTN ZNF302 23414517 0399 HT OPTN BRE 22863883 0401 LC OPTN TBK1 18307994,25923723,27035970,27035970,27035970,26365381,25923723,27620379,26365381,18307994,18307994,23414517,18307994 0096,0415,0004,0415,0096,0415,0428,0114,0004,0007,0018,0399,0004 LC,HT OPTN CDC23 25416956,25416956,25416956,21516116,25416956 1112,0397,0018,0018,1356 HT OPTN MYO6 26451915,15837803,15837803,15837803 0018,0096,0018,0004 LC OPTN SNX6 23414517,23414517 0813,0399 HT OPTN MACF1 20195357 0034 LC OPTN CCDC53 16189514,21516116,25416956,25416956,25416956,16189514,25416956 0398,0018,1112,0397,0018,0018,1356 HT OPTN RNF11 15231748 0018 HT OPTN ZNF711 23414517 0399 HT OPTN HEL-S-102 25277244 0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q96CV9 P61513 OPTN RPL37A 0.126 20195357 Q96CV9 P62158 OPTN CALM3 0.183 15840729 Q9HA65 Q96CV9 TBC1D17 OPTN 0.731 22854040,16189514 Q96CV9 Q8QXP6 OPTN Q8QXP6 0.126 22014111 Q9NQC7 Q96CV9 CYLD OPTN 0.74 21408173,25923723 Q96CV9 Q8TBN0 OPTN RAB3IL1 0.126 26186194 Q9NXR7 Q96CV9 BRE OPTN 0.081 22863883 Q9WUN2 Q96CV9 TBK1 OPTN 0.21 26376340 Q96CV9 P0CK53 OPTN P0CK53 0.183 17446270 Q96CV9 Q86YF9 OPTN DZIP1 0.126 23414517 Q96CV9 P01375 OPTN TNF 0.21 22675546 Q96CV9 P11055 OPTN MYH3 0.126 23414517 Q96CV9 P02786 OPTN TFRC 0.692 20161783,20085643,23357852,20634958 Q96CV9 P14335 OPTN P14335 0.126 22014111 Q96CV9 P07199 OPTN CENPB 0.126 20195357 Q9H492 Q96CV9 MAP1LC3A OPTN 0.74 21617041,25026213 Q96CV9 P04275 OPTN VWF 0.236 23414517 Q9Y3C5 Q96CV9 RNF11 OPTN 0.332 15231748 Q96CV9 P04792 OPTN HSPB1 0.286 25277244 Q96CV9 Q8TBZ3 OPTN WDR20 0.236 19615732 Q96CV9 Q8TC07 OPTN TBC1D15 0.583 25416956,unassigned1304 Q96CV9 P17021 OPTN ZNF17 0.236 unassigned1304 Q96CV9 O14949 OPTN UQCRQ 0.286 20195357 Q96CV9 O00560 OPTN SDCBP 0.236 unassigned1304 Q96CV9 O75604 OPTN USP2 0.236 unassigned1304 Q96CV9 Q04917 OPTN YWHAH 0.236 21903422 Q96CV9 P27348 OPTN YWHAQ 0.236 21903422 Q96CV9 P31946 OPTN YWHAB 0.236 21903422 Q96CV9 P40325 OPTN HUA1 0.49 27107014 Q96CV9 P40454 OPTN RRD1 0.416 27107014 Q96CV9 P78424 OPTN POU6F2 0.236 unassigned1304 Q96CV9 P61981 OPTN YWHAG 0.236 21903422 Q96CV9 P63104 OPTN YWHAZ 0.236 21903422 Q96CV9 Q96B67 OPTN ARRDC3 0.236 unassigned1304 Q96CV9 Q8IYE1 OPTN CCDC13 {ECO:0000312|HGNC:HGNC:26358} 0.236 unassigned1304 Q96CV9 Q8IX21 OPTN FAM178A 0.286 20195357 Q96CV9 Q49A26 OPTN GLYR1 0.236 unassigned1304 Q96CV9 Q8WZ42 OPTN TTN 0.236 23414517 Q96CV9 Q8N448 OPTN LNX2 0.332 21516116 Q96CV9 Q8N2W9 OPTN PIAS4 0.332 21988832 Q96CV9 Q8TF68 OPTN ZNF384 0.236 21903422 Q96CV9 Q8N5Z5 OPTN KCTD17 0.236 21903422 Q9GZV4 Q96CV9 EIF5A2 OPTN 0.236 21903422 Q9NZW5 Q96CV9 MPP6 OPTN 0.236 21903422 Q9NRD5 Q96CV9 PICK1 OPTN 0.236 unassigned1304 Q9NWF9 Q96CV9 RNF216 OPTN 0.236 unassigned1304 Q96CV9 Q15038 OPTN DAZAP2 0.583 25416956,unassigned1304 Q96CV9 Q15907 OPTN RAB11B 0.454 24056041 Q96CV9 A0A0G2JQ02 OPTN A0A0G2JQ02 0.236 unassigned1304 Q96CV9 Q12904 OPTN AIMP1 0.236 unassigned1304 Q96CV9 Q6IQ22 OPTN RAB12 0.454 23357852 Q96CV9 Q13255 OPTN GRM1 0.454 16091361 Q96CV9 O75031 OPTN HSF2BP 0.236 unassigned1304 Q96CV9 P61006 OPTN RAB8A 0.872 11137014,20161783,20085643,23357852,20634958 Q96CV9 P61007 OPTN RAB8A 0.523 11137014 Q96CV9 P61106 OPTN RAB14 0.523 19702578 Q96CV9 P40302 OPTN PRE5 0.49 27107014 Q96CV9 P54845 OPTN NRL 0.837 23956131 Q96CV9 P42858 OPTN HTT 0.895 11137014,17500595,9700202,23275563 Q96CV9 O75923 OPTN DYSF 0.298 23414517 Q96CV9 P01123 OPTN YPT1 0.554 27107014 Q96CV9 Q29122 OPTN MYO6 0.671 19805065 Q9UM54 Q96CV9 MYO6 OPTN 0.902 20161783,15837803,26971995,26451915 Q99732 Q96CV9 LITAF OPTN 0.332 25910212 Q9UJX2 Q96CV9 CDC23 OPTN 0.787 21516116,25416956,25910212 Q9BUY5 Q96CV9 ZNF426 OPTN 0.332 unassigned1304,23414517 Q9GZQ8 Q96CV9 MAP1LC3B OPTN 0.876 23805866,21617041,25026213 Q96CV9 P57735 OPTN RAB25 0.671 24056041 Q96CV9 Q13546 OPTN RIPK1 0.659 21408173,17702576,22675546 Q96CV9 P61026 OPTN RAB10 0.454 25416956 Q9Y3C0 Q96CV9 CCDC53 OPTN 0.884 25416956,16189514,unassigned1304,25910212,21516116 Q9NTZ6 Q96CV9 RBM12 OPTN 0.49 25910212,unassigned1304 Q96CV9 P0CG48 OPTN UBC 0.994 27035970,23178947,21862579,18212736,21617041,26365381,25969509,21408173,17702576,19285159,23414517,26451915 Q96CV9 Q15025 OPTN TNIP1 0.905 25416956,23414517,25910212,21988832,21516116,unassigned1304 Q96CV9 Q8IYU2 OPTN HACE1 0.99 25026213 Q9UHD2 Q96CV9 TBK1 OPTN 0.997 25803835,27035970,18307994,27086836,26365381,21903422,25923723,20174559,23414517 Q96CV9 Q96CV9 OPTN OPTN 0.908 25416956,20161783,23414517,24983867,25910212,unassigned1304 Q96CV9 P29882 OPTN P29882 0.126 22810586 Q96CV9 P38182 OPTN ATG8 0.523 21617041 Q96CV9 A0AUZ9 OPTN KANSL1L 0.126 23414517 Q96CV9 O60260 OPTN PARK2 0.126 25294927 Q96CV9 O95166 OPTN GABARAP 0.309 21617041 Q96CV9 O95197 OPTN RTN3 0.126 20195357 Q96CV9 O95467 OPTN GNAS 0.183 20195357 Q96CV9 P00441 OPTN SOD1 0.376 23178947 Q96CV9 P02794 OPTN FTH1 0.126 23414517 Q96CV9 P0CG47 OPTN UBB 0.126 23414517 Q96CV9 P13533 OPTN MYH6 0.376 25859013 Q96CV9 P19438 OPTN TNFRSF1A 0.21 22675546 Q96CV9 P20929 OPTN NEB 0.332 23414517 Q96CV9 P35280 OPTN RAB8A 0.21 24683533 Q96CV9 P37231 OPTN PPARG 0.126 20195357 Q96CV9 P38646 OPTN HSPA9 0.126 20195357 Q96CV9 P38936 OPTN CDKN1A 0.569 19609363 Q96CV9 P42566 OPTN EPS15 0.309 17626244 Q96CV9 P60520 OPTN GABARAPL2 0.309 21617041 Q96CV9 P62491 OPTN RAB11A 0.843 16905101,17626244,24056041 Q96CV9 P62991 OPTN UBA52 0.21 25026213 Q96CV9 P63092 OPTN GNAS 0.183 20195357 Q96CV9 P78344 OPTN EIF4G2 0.126 20195357 Q96CV9 P84996 OPTN GNAS 0.286 20195357 Q96CV9 Q00610 OPTN CLTC 0.126 23414517 Q96CV9 Q03001 OPTN DST 0.236 23414517 Q96CV9 Q13023 OPTN AKAP6 0.236 23414517 Q96CV9 Q13114 OPTN TRAF3 0.376 20174559 Q96CV9 Q14BN4 OPTN SLMAP 0.236 23414517 Q96CV9 Q15628 OPTN TRADD 0.21 17702576 Q96CV9 Q15884 OPTN FAM189A2 0.332 21516116 Q96CV9 Q5JWF2 OPTN GNAS 0.183 20195357 Q96CV9 Q86UD4 OPTN ZNF329 0.454 25416956 Q96CV9 Q86VP1 OPTN TAX1BP1 0.376 19609363 Q96CV9 Q8IUH5 OPTN ZDHHC17 0.523 24705354 Q96CV9 Q8N183 OPTN NDUFAF2 0.126 20195357 Q96CV9 Q8N3K9 OPTN CMYA5 0.126 23414517 Q96CV9 Q8TD17 OPTN ZNF398 0.454 25416956 Q96NC0 Q96CV9 ZMAT2 OPTN 0.126 20195357 Q99IB8 Q96CV9 Q99IB8 OPTN 0.286 24136289 Q9BXW4 Q96CV9 MAP1LC3C OPTN 0.309 26451915 Q9H0R8 Q96CV9 GABARAPL1 OPTN 0.623 21617041 Q9NR11 Q96CV9 ZNF302 OPTN 0.126 23414517 Q9UNH7 Q96CV9 SNX6 OPTN 0.236 23414517 Q9UPN3 Q96CV9 MACF1 OPTN 0.126 20195357 Q9Y462 Q96CV9 ZNF711 OPTN 0.126 23414517 Q99848 Q96CV9 EBNA1BP2 OPTN 0.126 20195357 Q9BS34 Q96CV9 ZNF670 OPTN 0.583 25416956,unassigned1304 Q96PV0 Q96CV9 SYNGAP1 OPTN 0.126 20195357 Q96CV9 Q00013 OPTN MPP1 0.454 21903422 Q96CV9 Q15018 OPTN FAM175B 0.126 20195357 Q96CV9 Q13501 OPTN SQSTM1 0.787 25026213 Q96CV9 Q2M3W8 OPTN ZNF181 0.126 23414517 Q96CV9 P55072 OPTN VCP 0.126 23414517

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 KANSL1L OPTN MI:0045 experimental interaction detection MI:0461 interaction database IKBKB OPTN MI:0362 inference MI:0461 interaction database UQCRQ OPTN MI:0045 experimental interaction detection MI:0461 interaction database USP2 OPTN MI:0362 inference MI:0461 interaction database DYSF OPTN MI:0045 experimental interaction detection MI:0461 interaction database GABARAP OPTN MI:0045 experimental interaction detection MI:0461 interaction database RTN3 OPTN MI:0045 experimental interaction detection MI:0461 interaction database GNAS OPTN MI:0045 experimental interaction detection MI:0461 interaction database SOD1 OPTN MI:0045 experimental interaction detection MI:0461 interaction database FOS OPTN MI:0362 inference MI:0461 interaction database TNF OPTN MI:0045 experimental interaction detection MI:0461 interaction database TFRC OPTN MI:0045 experimental interaction detection MI:0461 interaction database FTH1 OPTN MI:0045 experimental interaction detection MI:0461 interaction database VWF OPTN MI:0045 experimental interaction detection MI:0461 interaction database HSPB1 OPTN MI:0045 experimental interaction detection MI:0461 interaction database CENPB OPTN MI:0045 experimental interaction detection MI:0461 interaction database UBB OPTN MI:0045 experimental interaction detection MI:0461 interaction database UBC OPTN MI:0045 experimental interaction detection MI:0461 interaction database MYH3 OPTN MI:0045 experimental interaction detection MI:0461 interaction database MYH6 OPTN MI:0045 experimental interaction detection MI:0461 interaction database TNFRSF1A OPTN MI:0045 experimental interaction detection MI:0461 interaction database RAB4A OPTN MI:0045 experimental interaction detection MI:0461 interaction database NEB OPTN MI:0045 experimental interaction detection MI:0461 interaction database UBA1 OPTN MI:0362 inference MI:0461 interaction database PSMA1 OPTN MI:0362 inference MI:0461 interaction database YWHAQ OPTN MI:0045 experimental interaction detection MI:0461 interaction database YWHAB OPTN MI:0045 experimental interaction detection MI:0461 interaction database PPARG OPTN MI:0045 experimental interaction detection MI:0461 interaction database HSPA9 OPTN MI:0045 experimental interaction detection MI:0461 interaction database CDKN1A OPTN MI:0045 experimental interaction detection MI:0461 interaction database EPS15 OPTN MI:0045 experimental interaction detection MI:0461 interaction database HTT OPTN MI:0045 experimental interaction detection MI:0461 interaction database PLK1 OPTN MI:0362 inference MI:1106 pathways database NRL OPTN MI:0045 experimental interaction detection MI:0461 interaction database VCP OPTN MI:0045 experimental interaction detection MI:0461 interaction database RAB25 OPTN MI:0045 experimental interaction detection MI:0461 interaction database GABARAPL2 OPTN MI:0045 experimental interaction detection MI:0461 interaction database RAB8A OPTN MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RAB10 OPTN MI:0045 experimental interaction detection MI:0461 interaction database RAB14 OPTN MI:0045 experimental interaction detection MI:0461 interaction database RPL37A OPTN MI:0045 experimental interaction detection MI:0461 interaction database YWHAG OPTN MI:0045 experimental interaction detection MI:0461 interaction database CALM1 OPTN MI:0045 experimental interaction detection MI:0461 interaction database RAB11A OPTN MI:0045 experimental interaction detection MI:0461 interaction database RAB1A OPTN MI:0362 inference MI:0461 interaction database RPS27A OPTN MI:0362 inference MI:0461 interaction database UBA52 OPTN MI:0362 inference MI:0461 interaction database GNAS OPTN MI:0045 experimental interaction detection MI:0461 interaction database YWHAZ OPTN MI:0045 experimental interaction detection MI:0461 interaction database UBE2L3 OPTN MI:0362 inference MI:0461 interaction database EIF4G2 OPTN MI:0045 experimental interaction detection MI:0461 interaction database GNAS OPTN MI:0045 experimental interaction detection MI:0461 interaction database MPP1 OPTN MI:0045 experimental interaction detection MI:0461 interaction database CLTC OPTN MI:0045 experimental interaction detection MI:0461 interaction database CNTN2 OPTN MI:0045 experimental interaction detection MI:0461 interaction database DST OPTN MI:0045 experimental interaction detection MI:0461 interaction database YWHAH OPTN MI:0045 experimental interaction detection MI:0461 interaction database AKAP6 OPTN MI:0045 experimental interaction detection MI:0461 interaction database TRAF3 OPTN MI:0045 experimental interaction detection MI:0461 interaction database GRM1 OPTN MI:0045 experimental interaction detection MI:0461 interaction database SQSTM1 OPTN MI:0045 experimental interaction detection MI:0461 interaction database RIPK1 OPTN MI:0045 experimental interaction detection MI:0461 interaction database SLMAP OPTN MI:0045 experimental interaction detection MI:0461 interaction database FAM175B OPTN MI:0045 experimental interaction detection MI:0461 interaction database TNIP1 OPTN MI:0045 experimental interaction detection MI:0461 interaction database DAZAP2 OPTN MI:0045 experimental interaction detection MI:0461 interaction database PPP2R4 OPTN MI:0362 inference MI:0461 interaction database TRADD OPTN MI:0045 experimental interaction detection MI:0461 interaction database FAM189A2 OPTN MI:0045 experimental interaction detection MI:0461 interaction database RAB11B OPTN MI:0045 experimental interaction detection MI:0461 interaction database ZNF181 OPTN MI:0045 experimental interaction detection MI:0461 interaction database GNAS OPTN MI:0045 experimental interaction detection MI:0461 interaction database RAB12 OPTN MI:0045 experimental interaction detection MI:0461 interaction database ZNF329 OPTN MI:0045 experimental interaction detection MI:0461 interaction database TAX1BP1 OPTN MI:0045 experimental interaction detection MI:0461 interaction database STX12 OPTN MI:0045 experimental interaction detection MI:0461 interaction database DZIP1 OPTN MI:0045 experimental interaction detection MI:0461 interaction database ZDHHC17 OPTN MI:0045 experimental interaction detection MI:0461 interaction database SLF2 OPTN MI:0045 experimental interaction detection MI:0461 interaction database HACE1 OPTN MI:0045 experimental interaction detection MI:0461 interaction database NDUFAF2 OPTN MI:0045 experimental interaction detection MI:0461 interaction database PIAS4 OPTN MI:0045 experimental interaction detection MI:0461 interaction database CMYA5 OPTN MI:0045 experimental interaction detection MI:0461 interaction database LNX2 OPTN MI:0045 experimental interaction detection MI:0461 interaction database KCTD17 OPTN MI:0045 experimental interaction detection MI:0461 interaction database RAB3IL1 OPTN MI:0045 experimental interaction detection MI:0461 interaction database WDR20 OPTN MI:0045 experimental interaction detection MI:0461 interaction database TBC1D15 OPTN MI:0045 experimental interaction detection MI:0461 interaction database ZNF398 OPTN MI:0045 experimental interaction detection MI:0461 interaction database ZNF384 OPTN MI:0045 experimental interaction detection MI:0461 interaction database TTN OPTN MI:0045 experimental interaction detection MI:0461 interaction database OPTN ZMAT2 MI:0045 experimental interaction detection MI:0461 interaction database OPTN SYNGAP1 MI:0045 experimental interaction detection MI:0461 interaction database OPTN EBNA1BP2 MI:0045 experimental interaction detection MI:0461 interaction database OPTN ZNF670 MI:0045 experimental interaction detection MI:0461 interaction database OPTN ZNF426 MI:0045 experimental interaction detection MI:0461 interaction database OPTN MAP1LC3C MI:0045 experimental interaction detection MI:0461 interaction database OPTN MAP1LC3B MI:0045 experimental interaction detection MI:0461 interaction database OPTN EIF5A2 MI:0045 experimental interaction detection MI:0461 interaction database OPTN GABARAPL1 MI:0045 experimental interaction detection MI:0461 interaction database OPTN RAB1B MI:0362 inference MI:0461 interaction database OPTN SEMA4A MI:0362 inference MI:0461 interaction database OPTN MAP1LC3A MI:0045 experimental interaction detection MI:0461 interaction database OPTN TBC1D17 MI:0045 experimental interaction detection MI:0461 interaction database OPTN CYLD MI:0045 experimental interaction detection MI:0461 interaction database OPTN ZNF302 MI:0045 experimental interaction detection MI:0461 interaction database OPTN MPP6 MI:0045 experimental interaction detection MI:0461 interaction database OPTN TBK1 MI:0045 experimental interaction detection MI:0461 interaction database OPTN CDC23 MI:0045 experimental interaction detection MI:0461 interaction database OPTN ASAP1 MI:0045 experimental interaction detection MI:0461 interaction database OPTN MYO6 MI:0045 experimental interaction detection MI:0461 interaction database OPTN SNX6 MI:0045 experimental interaction detection MI:0461 interaction database OPTN MACF1 MI:0045 experimental interaction detection MI:0461 interaction database OPTN CCDC53 MI:0045 experimental interaction detection MI:0461 interaction database OPTN RNF11 MI:0045 experimental interaction detection MI:0461 interaction database OPTN ZNF711 MI:0045 experimental interaction detection MI:0461 interaction database