PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus TSG101 GGA3 15039775 hprd,biogrid,intact,bci exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G MOV10 GGA3 22658674 biogrid exp G G G G G G G G G G G G G G G G G G G G G G TMEM17 GGA3 26638075 biogrid,intact exp P GP G P GP G P P G GP P P G G P GP P GP G P G GP P P P P GP UBA52 GGA3 i2d exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G M6PR GGA3 11859375,11387475 hprd,biogrid,mint,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G TOLLIP GGA3 15047686 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP G GP GP G ARF6 GGA3 20848231,19327867,18199687,23143332 biogrid,dip exp GP GP G G G GP G G GP G GP GP GP GP G GP GP GP GP G GP G GP G GP GP GP GP G UBB GGA3 15039775 i2d,intact,bci exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G GGA3 NXF1 22658674 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G GGA3 RNF11 25195858,15231748 hprd,biogrid,i2d,mint,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G HAUS4 GGA3 26344197 biogrid exp P P P P P P P P P P P P P P P P P P NEDD4 GGA3 17116753 biogrid exp GP GP G GP P G GP GP GP G GP GP G GP GP GP GP G GP G GP GP GP GP GP P G RPS27A GGA3 15039775 hprd,i2d,bci exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G AFTPH GGA3 14665628 hprd exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP G GP GP GP G GP GP G TBC1D3 GGA3 18199687 biogrid exp CDKN2A GGA3 21517092 biogrid exp G GP G G GP GP G G G G G G GP GP G G GP G GP G GP G G G G GP GP G G GGA3 GGA3 10814529 hprd,i2d exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G MON2 GGA3 18418388 biogrid,mint,intact exp G G G G G GP G GP GP G GP GP G G G G GP G GP G G G G GP G G GP GP G UBC GGA3 15701688,15494413,15966896,20484053,16135791,14660606 biogrid,i2d,bci exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G ITCH GGA3 25195858 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G CRK GGA3 21664574 biogrid exp GP G G G G G G GP GP G GP GP G G G GP G G GP G GP G GP GP GP G GP G G MET GGA3 21664574 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G TGOLN2 GGA3 16977309 mint,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G RABEP1 GGA3 16473621,12858162,12505986,14665628, 25402006, 21836163 hprd,biogrid,intact,bci exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G HGS GGA3 15611048, 25402006, 23023127, 21836163 mint,intact exp, pred GP GP G G GP GP G GP GP G GP G GP G G GP GP GP GP G GP G GP GP GP G GP GP G CLINT1 GGA3 12858162, 25402006, 23023127 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP G GP G GP GP GP GP G BACE1 GGA3 14567678, 21836163 biogrid exp, pred G GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP G G GP GP GP GP GP G ARF1 GGA3 11301005,11950392,10747089, 25402006, 21836163 hprd,biogrid exp, pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP G P G GP G GP P P GP GP GP G ARF3 GGA3 10749927,12221117, 25402006 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GGA3 SYNRG 10814529,12858162, 25402006, 21836163 hprd,biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G IGF2R GGA3 11859375,12060753,12032548,11387475,16135791,14567678,11390366,16977309, 25402006, 16082366 hprd,biogrid,mint,intact exp, pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP G GP G GP GP GP GP G GGA3 GGA2 14638859, 25402006, 23023127 biogrid,bci exp, pred GP GP G G G GP G G GP G GP GP GP GP G GP GP GP GP G GP G GP G GP GP GP GP G GGA3 VPS18 16996030, 25402006, 21836163 biogrid exp, pred GP GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP G GP G GP G GP GP G LAPTM5 GGA3 17116753, 21836163 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G G GP G GP GP GP GP G STAB1 GGA3 15345724, 21836163 biogrid exp, pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G AP1S2 GGA3 12215646, 25402006 hprd,bci exp, pred G GP G G G GP G GP GP G GP GP G G G GP GP G GP G GP G G GP GP G GP GP G PACS1 GGA3 16977309, 25402006, 21836163 hprd,biogrid,mint,intact exp, pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G SORT1 GGA3 11390366, 25402006 biogrid exp, pred G G G G GP GP G GP GP G GP G GP G G G GP G GP G GP G G GP G G G GP G CLTC GGA3 11301005, 25402006, 21836163, 16082366 hprd,biogrid,bci exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP G GP G GP GP GP GP G GGA3 GGA1 14638859, 25402006, 23023127 biogrid exp, pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP G GP G GP GP GP GP G VPS11 GGA3 16996030, 25402006 biogrid exp, pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP G GP GP GP G GP GP G YWHAE GGA3 ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G ASAP2 GGA3 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP G GP G GP P GP GP G NCF2 GGA3 23023127 pred G G GP G G G GP GP G G G G G G G G GP G G KRT18 GGA3 23023127 pred GP GP G G G G G GP G GP GP GP G G GP G G GP G GP G GP G GP G GP G G HUWE1 GGA3 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G GGA3 MAPK8IP1 23023127 pred P P G P GP G P P G P P P P P GP P G P P P P P P GP STX16 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G USE1 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP P G GP GP GP GP GP GP G STX1B GGA3 23023127 pred G G G G G PRKCI GGA3 23023127 pred GP GP G G G GP G G GP G GP G GP G G GP GP G GP G GP G G G GP G GP GP G UBQLNL GGA3 23023127 pred P P P P P P P P G P P P P GP PDCD6IP GGA3 23023127 pred G GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G STX7 GGA3 25402006, 23023127 pred G G G G G G G G GP G GP G G GP G G G G G G G G G G G GP GP GP G STAM GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP G GP G GP GP G RASSF9 GGA3 23023127 pred G P P P G GP P P P P P P P P GP P P P P STAMBP GGA3 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G GGA3 VPS28 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G CIDEC GGA3 23023127 pred G GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G USO1 GGA3 21836163 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP G GP GP GP GP GP GP G DCDC2B GGA3 23023127 pred P G G G G G G P COPB1 GGA3 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G UBTD2 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP G GP GP GP GP GP GP G CLTCL1 GGA3 21836163 pred STX12 GGA3 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP G GP G GP G GP GP G STX1A GGA3 23023127 pred G G G GP G G P G G G G GP GP GP G G G G G GP GP G G ARL1 GGA3 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GGA3 SEC23IP 23023127 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP G GP G GP GP GP GP G GABARAP GGA3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ASPSCR1 GGA3 23023127 pred GP GP G P GP G GP P G GP GP GP GP G GP GP P GP G GP G GP GP GP G GP GP GGA3 AP4E1 25402006 pred GP GP G G G G GP G G GP G GP G G GP G G P G G G GP GP GP G GP GP G AP1G2 GGA3 25402006, 23023127, 21836163 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP G GP P GP GP GP GP G SUMO2 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G ZFYVE9 GGA3 23023127 pred G GP G G G GP G G GP G GP G G G G GP GP GP GP G GP G G G GP GP GP GP G LRSAM1 GGA3 21836163 pred P GP G P GP G P GP G GP GP P GP P GP GP GP G P G P P P GP P P G BAG1 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G SPTBN1 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G HERPUD1 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G GGA3 RABGEF1 25402006 pred P P P P P GP G GP P P P GP P P GP G P GP P P GP P P GGA3 RABGEF1 25402006 pred P P P P P GP G GP P P P GP P P GP G P GP P P GP P P SYNE1 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G SUMO3 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G BAG6 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G UBFD1 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G PEX5 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G UBL4B GGA3 23023127 pred P P P P P P P P P P P P P P P P P P P FLNA GGA3 23023127 pred G G G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP G G G G G GP GP G UBXN11 GGA3 23023127 pred G GP G G G GP G GP P G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G STX2 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP G GP GP GP GP GP GP G DDI2 GGA3 23023127 pred P P P P P P P P P P P P P P GGA3 RERE 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP G GP G GP GP GP GP G TOM1 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP 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23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP G GP GP GP GP GP GP G RANBP3 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G UBXN7 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G UHRF2 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G CYTH1 GGA3 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G G G G G GP GP GP GP G LIN7A GGA3 23023127 pred G G G G G G G G G G G G G G G G G G G RAD23A GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G SNX1 GGA3 23023127, 21836163 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G G G GP G GP G GP GP G RABEP2 GGA3 25402006 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP GP G GP G GP G GP GP GP GP G ITSN1 GGA3 16082366 pred G GP G G G GP G GP GP G GP GP GP GP G GP GP G G G GP G GP GP GP G GP GP G EP300 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G ZFYVE16 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP G GP GP G CSNK2B GGA3 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G GGA3 FAF1 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G CLTCL1 GGA3 16082366 pred G G G G G G G G G G G G G G G G G XPO1 GGA3 16082366 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G PPP1R10 GGA3 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP G GP GP GP G GP GP G GOSR1 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G GGA3 ASAP1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP G GP GP GP GP G CIDEA GGA3 23023127 pred G G G G G G G G MSR1 GGA3 23023127 pred G G GP G G GP G GP G P UBLCP1 GGA3 23023127 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G GGA3 PIKFYVE 21836163 pred GP GP G G GP GP G GP GP G GP G GP G G GP GP GP GP G GP G GP GP GP G GP GP G EPB41L5 GGA3 23023127 pred G GP G G GP GP G G G G GP GP G G G GP GP G GP G GP G G G GP P GP GP G STX4 GGA3 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G GGA3 NSFL1C 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP G GP GP GP GP G LIN7B GGA3 23023127 pred G G G G G GP G G GP G G GP G G GP GP GP G G G G GP G GP GP G VPS16 GGA3 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G MON1B GGA3 25402006 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP GP GP G GP G GP G GP GP GP P G STX11 GGA3 23023127 pred GP P G GP P P GP P P GP P G P P P P GP P P P GP GP P AP1G1 GGA3 25402006, 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G STX3 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP G GP GP GP GP GP GP G ARFIP2 GGA3 25402006 pred GP GP G G G GP G GP GP G GP G GP G G GP GP G GP G GP G GP G GP G GP GP G STAB2 GGA3 21836163 pred GP GP G G G GP G GP GP G G GP G G P GP G G GP GP G P G GP G G NAPG GGA3 16082366 pred G GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP G G GP GP GP GP GP G STX6 GGA3 23023127 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP G GP G GP G GP G GP GP GP GP G MIDN GGA3 23023127 pred GP GP G G GP GP G GP GP G GP G G G G GP GP G G G GP G GP GP GP G GP GP G IGF2 GGA3 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP G GP GP GP GP G EEA1 GGA3 21836163 pred GP GP G G GP GP G G GP G GP G GP G G GP GP GP GP G GP G GP GP GP G GP GP G FURIN GGA3 25402006 pred G GP G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP G GP G GP GP GP GP G DVL1 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G DFFA GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G ARFIP1 GGA3 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G GGA3 FRMD4A 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G G G GP GP GP GP GP GP G FRMD7 GGA3 23023127 pred P P P P P P P P P P P P P P P P P P SUMO4 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G G GP GP GP G GP G GP GP G GP GP GP G STX10 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G HERPUD2 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G RASSF8 GGA3 23023127 pred GP GP G P GP G GP GP G GP P G P G GP GP G P G GP G P GP GP P GP GP G DCLK1 GGA3 23023127 pred G G G GP G G GP G GP G GP GP GP GP G P G G G GP GP GP P G UBL7 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP G GP GP GP GP G CLTA GGA3 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP G GP G GP G GP GP G AKAP1 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G TOM1L1 GGA3 23023127 pred GP GP P P G GP GP GP GP GP GP G GP P GP GP G P G GP GP P GP GP G UBXN4 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G RAB4A GGA3 25402006 pred P P P P P P P P P P P P P P P P P P P P P EZR GGA3 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP G GP G GP GP GP GP G MACF1 GGA3 23023127 pred FRMD3 GGA3 23023127 pred GP GP G G G GP G GP G G GP GP GP G GP GP GP GP G GP G G G GP GP GP GP G RDX GGA3 23023127 pred G GP G G G GP G G G G GP GP G GP G G GP GP GP G GP G GP G G G GP GP G GGA3 SNX13 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G STX5 GGA3 23023127 pred GP GP G G GP GP G G G G GP GP GP GP G G GP G GP G GP G GP G G G GP GP G UBTD1 GGA3 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G G GP GP GP G P G GP G G G GP G GGA3 UBQLN1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G SNX3 GGA3 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G UBXN10 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP GP GP GP G GP G GP GP GP G GP GP G PLCB3 GGA3 23023127 pred G G G G G GP G G G G G G G G G GP GP G G G G G G G GP G G G G PIK3CA GGA3 23023127 pred GP GP G P GP G GP GP G GP GP GP GP G P GP GP GP G P G GP GP GP GP GP GP TMUB2 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G PEX19 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G RIN2 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP G GP GP GP GP GP P G SQSTM1 GGA3 23023127 pred GP GP G G GP G G G GP G GP GP GP GP G GP G GP GP G GP G GP GP GP GP GP GP G PLD2 GGA3 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP G GP G GP GP G USP14 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G AMPH GGA3 23023127 pred G G G G GP G G GP G G G G G GP G GP G G G G G G G G G GGA3 AXIN2 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G UBXN2B GGA3 23023127 pred G GP G G G G G G GP G GP G GP G G GP G GP G G G G G G GP G GP GP G GGA3 TRAK1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP G GP GP GP GP GP GP G CDC37 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G AP2B1 GGA3 25402006, 23023127 pred G GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP G GP G GP GP GP GP G KDELR1 GGA3 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP G GP GP GP GP GP GP G SORL1 GGA3 16082366 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP GP GP GP G NFATC2IP GGA3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G COG3 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G EPB41L4B GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP P GP GP G SNX2 GGA3 23023127, 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP G G G GP GP GP GP G CHMP6 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G GGA3 UBQLN2 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G STAM2 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G TMUB1 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP G GP GP G CHMP4B GGA3 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP G G GP GP GP GP GP G UBC GGA3 23023127 pred C3 GGA3 23023127 pred GP G G G G G G G GP GP G GP G G G G G G GP G G G G G GP G G LYST GGA3 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RAB5C GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G TOM1L2 GGA3 23023127 pred G GP G G GP GP G GP GP G GP GP G GP G GP GP G GP G GP G GP G GP G GP GP G UBL4A GGA3 23023127 pred GP GP G G G GP G G GP G GP G G G G G GP G GP G GP G G G G G GP P G PLIN3 GGA3 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G SUMO1 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G ARAF GGA3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN2A GGA3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GGA3 TACC3 23023127 pred P G GP P GP P P GP GP P P P P GP GP GP GP GGA3 UVRAG 25402006 pred G G G G G GP G GP G G GP G GP G G G GP G G G GP G G G G G GP GP G SPTBN2 GGA3 23023127 pred GP GP G GP G G GP GP P P GP GP G G GP P P P GP MYO7B GGA3 23023127 pred P P G G G P P P GP G GP G G G G GP G GP G P G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9NZ52 Q9NZ52 - 11859375 - X 2 Q9NZ52 Q9NZ52 - 11859375,12032548 - X 2 Q9NZ52 Q9NZ52 - 11859375,12032548 - X 2 Q9NZ52 Q9NZ52 - 12032548 - X 2 Q9NZ52 Q9NZ52 - 12032548 - X 2 Q9NZ52 Q9NZ52 - 12032548 - X 2 Q9NZ52 Q9NZ52 - 11859375 - X 2 Q9NZ52 Q9NZ52 - 11859375,12032548 - X 2 Q9NZ52 Q9NZ52 - 11859375,12032548 - X 2 Q9NZ52 Q9NZ52 - 12032548 - X 2 Q9NZ52 Q9NZ52 - 12032548 - X 2 Q9NZ52 Q9NZ52 - 12032548 - X 2 Q9NZ52 - 11859375 - X 2 Q9NZ52 - 11859375 - X 2 Q9NZ52 - 11859375 - X 2 Q9NZ52 - 11859375 - X 2 Q9NZ52 - 11859375 - X 2 Q9NZ52 - 11859375 - X 2 Q9NZ52 - 12032548 - X 2 Q9NZ52 - 12032548 - X 2 Q9NZ52 - 12032548 - X 2 Q9NZ52 - 12032548 - X 2 Q9NZ52 - 12032548 - X 2 Q9NZ52 - 12032548 - X 2 Q9NZ52 - 12032548 - X 2 Q9NZ52 - 12032548 - X 2 Q9NZ52 Q9Y3C5 - 15231748 - X 2 Q9NZ52 P62330 pull down 23143332 physical association X 2 Q9NZ52 P49951 pull down 11301005 direct interaction X 2 Q9NZ52 P20645 two hybrid 11387475 physical association X 2 Q9NZ52 O18973 pull down 12505986 physical association X 2 Q9NZ52 P0CG47 two hybrid 15039775 physical association X 2 Q9NZ52 P0CG47 affinity chromatography technology 15039775 physical association X 2 Q9NZ52 O88588 anti bait coimmunoprecipitation 16977309 physical association X 2 Q9NZ52 Q7Z3U7 anti tag coimmunoprecipitation 18418388 physical association X 2 O43493 Q9NZ52 imaging technique 16977309 colocalization X 2 P11717 Q9NZ52 two hybrid 11387475 physical association X 2 P11717 Q9NZ52 pull down 16977309 direct interaction X 2 P11717 Q9NZ52 imaging technique 16977309 colocalization X 2 Q15276 Q9NZ52 two hybrid 12505986 physical association X 2 Q15276 Q9NZ52 anti tag coimmunoprecipitation 12505986 physical association X 2 Q15276 Q9NZ52 two hybrid 12505986 physical association X 2 Q15276 Q9NZ52 two hybrid 12505986 physical association X 2 Q9NZ52 P84080 two hybrid 10747089 physical association X 2 Q9NZ52 P84080 pull down 10747089 direct interaction X 2 Q9NZ52 P84080 two hybrid 11301005 physical association X 2 Q9NZ52 Q99816 two hybrid 15039775 physical association X 2 Q9NZ52 Q9Y3C5 two hybrid 15231748 physical association X 2 Q9NZ52 O14964 two hybrid 15611048 physical association X 2 Q9NZ52 P0CG53 surface plasmon resonance 20150893 direct interaction X 2 A0A024R5H6 Q9NZ52 pull down 16977309 direct interaction X 2 A0A024R5H6 Q9NZ52 pull down 16977309 direct interaction X 2 A0A024R5H6 Q9NZ52 anti tag coimmunoprecipitation 16977309 physical association X 2 A0A024R5H6 Q9NZ52 anti tag coimmunoprecipitation 16977309 physical association X 2 A0A024R5H6 Q9NZ52 pull down 16977309 direct interaction X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B BACE1 GGA3 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 14567678 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_195598|BIOGRID_195602 bait|bait prey|prey RABEP1 GGA3 MI:0096(pull down)|MI:0686(unspecified method)|MI:0686(unspecified method)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0492(in vitro)|MI:0686(unspecified method)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down) 12505986,12858162,16473621 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|-|MI:0407(direct interaction)|MI:0915(physical association)|MI:0914(association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(intact)|(intact)|(biogrid)|MI:0468(hprd)|(biogrid)|(intact)|(biogrid)|(intact) BIOGRID_105060|BIOGRID_194512|BIOGRID_194511|UniProt_72160|UniProt_72151|BIOGRID_207641|HPRD_12553|BIOGRID_194508|UniProt_72154|BIOGRID_207644|UniProt_72156 prey|prey|prey|prey|prey|prey|-|prey|prey|prey|prey bait|bait|bait|bait|bait|bait|-|bait|bait|bait|bait MON2 GGA3 MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down) 18418388 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|MI:0471(mint)|(intact) BIOGRID_251737|MINT_38228|MINT_67411|UniProt_95625 prey|prey|prey|prey bait|bait|bait|bait RPS27A GGA3 MI:0492(in vitro) 15039775 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_4734 - - TOLLIP GGA3 MI:0004(affinity chromatography technology) 15047686 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_195244 prey bait ARF3 GGA3 MI:0018(two hybrid)|MI:0018(two hybrid) 10749927,12221117 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_116990|BIOGRID_81453 bait|bait prey|prey MET GGA3 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21664574 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0403(colocalization) (biogrid)|(biogrid) BIOGRID_220430|BIOGRID_220431 bait|bait prey|prey UBB GGA3 MI:0018(two hybrid)|MI:0018(two hybrid) 15039775 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_74299|UniProt_74301 bait|bait prey|prey ARF6 GGA3 MI:0004(affinity chromatography technology)|MI:0096(pull down) 18199687,20848231 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_164070|BIOGRID_195629 prey|prey bait|bait M6PR GGA3 MI:0114(x-ray crystallography)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0492(in vitro)|MI:0096(pull down) 11387475,11859375 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|-|MI:0915(physical association) (biogrid)|MI:0471(mint)|MI:0471(mint)|(biogrid)|MI:0468(hprd)|(intact) BIOGRID_216492|MINT_78206|MINT_48755|BIOGRID_97680|HPRD_37388|UniProt_68805 prey|prey|prey|bait|-|prey bait|bait|bait|prey|-|bait SORT1 GGA3 MI:0004(affinity chromatography technology) 11390366 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_215606 bait prey AFTPH GGA3 MI:0018(two hybrid) 14665628 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_15583 - - TSG101 GGA3 MI:0018(two hybrid)|MI:0492(in vitro)|MI:0018(two hybrid) 15039775 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|-|MI:0915(physical association) (biogrid)|MI:0468(hprd)|(intact) BIOGRID_78139|HPRD_9038|UniProt_74300 prey|-|bait bait|-|prey RAB5A GGA3 MI:0004(affinity chromatography technology) 14665628 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_87279 bait prey GGA3 GGA1 MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique) 14638859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_210739|BIOGRID_210744|BIOGRID_210741 prey|bait|prey bait|prey|bait GGA3 GGA2 MI:0428(imaging technique)|MI:0428(imaging technique) 14638859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_210745|BIOGRID_210743 bait|prey prey|bait TGOLN2 GGA3 MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 16977309 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization) (intact)|MI:0471(mint)|MI:0471(mint) UniProt_88637|MINT_51563|MINT_83915 neutral component|neutral component|neutral component neutral component|neutral component|neutral component GGA3 SYNRG MI:0493(in vivo)|MI:0686(unspecified method) 10814529,12858162 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction) MI:0468(hprd)|(biogrid) HPRD_14236|BIOGRID_194509 -|bait -|prey CLTC GGA3 MI:0018(two hybrid)|MI:0492(in vitro) 11301005 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_98851|HPRD_20119 prey|- bait|- LAPTM5 GGA3 MI:0004(affinity chromatography technology) 17116753 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_122138 bait prey NEDD4 GGA3 MI:0004(affinity chromatography technology) 17116753 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_122140 bait prey CRK GGA3 MI:0004(affinity chromatography technology) 21664574 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_220433 bait prey Pacs1 GGA3 MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 16977309 taxid:10116(Rattus norvegicus) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint)|MI:0471(mint)|(intact) UniProt_183656|MINT_51553|MINT_83905|UniProt_88621 bait|bait|bait|bait prey|prey|prey|prey TBC1D3 GGA3 MI:0096(pull down)|MI:0096(pull down) 18199687 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_195628|BIOGRID_195627 prey|prey bait|bait ARF1 GGA3 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0492(in vitro) 10747089,11301005 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|- (biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_98847|BIOGRID_99126|BIOGRID_98848|BIOGRID_77234|HPRD_35038 bait|bait|prey|bait|- prey|prey|bait|prey|- AP1S2 GGA3 MI:0492(in vitro) 12215646 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_12471 - - PACS1 GGA3 MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0493(in vivo)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0493(in vivo) 16977309 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|- MI:0471(mint)|(biogrid)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(biogrid)|(intact)|MI:0471(mint)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0468(hprd)|MI:0471(mint)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|(intact)|(intact)|(intact)|(intact)|MI:0471(mint)|MI:0468(hprd) MINT_51556|BIOGRID_154489|MINT_51555|MINT_83911|BIOGRID_154487|BIOGRID_154488|UniProt_183659|MINT_83906|UniProt_183657|MINT_51554|MINT_51571|HPRD_32547|MINT_83923|UniProt_183658|UniProt_88634|MINT_83908|MINT_83907|UniProt_88623|UniProt_88631|UniProt_88622|UniProt_88624|MINT_51559|HPRD_39927 prey|prey|prey|bait|bait|bait|prey|bait|bait|bait|bait|-|bait|prey|bait|prey|prey|prey|bait|bait|prey|bait|- bait|bait|bait|prey|prey|prey|bait|prey|prey|prey|prey|-|prey|bait|prey|bait|bait|bait|prey|prey|bait|prey|- IGF2R GGA3 MI:0018(two hybrid)|MI:0006(anti bait coimmunoprecipitation)|MI:0018(two hybrid)|MI:0006(anti bait coimmunoprecipitation)|MI:0415(enzymatic study)|MI:0006(anti bait coimmunoprecipitation)|MI:0018(two hybrid)|MI:0006(anti bait coimmunoprecipitation)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0492(in vitro)|MI:0006(anti bait coimmunoprecipitation)|MI:0114(x-ray crystallography)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0114(x-ray crystallography)|MI:0018(two hybrid)|MI:0006(anti bait coimmunoprecipitation)|MI:0493(in vivo) 11387475,11390366,11859375,12032548,12060753,14567678,16135791,16977309 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0914(association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0403(colocalization)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0403(colocalization)|MI:0914(association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|- (biogrid)|MI:0471(mint)|(biogrid)|MI:0471(mint)|(biogrid)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(biogrid)|(intact)|MI:0471(mint)|MI:0468(hprd)|(intact)|(biogrid)|(biogrid)|(intact)|(biogrid)|(biogrid)|(intact)|MI:0468(hprd) BIOGRID_195224|MINT_83916|BIOGRID_195225|MINT_51564|BIOGRID_195777|MINT_83924|MINT_48682|MINT_51572|BIOGRID_195223|BIOGRID_195595|UniProt_68804|MINT_78109|HPRD_36260|UniProt_88638|BIOGRID_216491|BIOGRID_215610|UniProt_88627|BIOGRID_216495|BIOGRID_194109|UniProt_183662|HPRD_39927 bait|bait|bait|bait|bait|neutral component|bait|neutral component|bait|bait|bait|bait|-|neutral component|prey|bait|bait|bait|bait|bait|- prey|prey|prey|prey|prey|neutral component|prey|neutral component|prey|prey|prey|prey|-|neutral component|bait|prey|prey|prey|prey|prey|- CLINT1 GGA3 MI:0686(unspecified method) 12858162 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_194510 prey bait STAB1 GGA3 MI:0096(pull down) 15345724 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_207845 bait prey GGA3 RNF11 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15231748 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0407(direct interaction) (intact)|MI:0471(mint)|MI:0471(mint)|MI:0468(hprd)|(biogrid) UniProt_78516|MINT_31427|MINT_60192|HPRD_37420|BIOGRID_259442 prey|prey|prey|-|prey bait|bait|bait|-|bait GGA3 VPS18 MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down) 16996030 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_122357|BIOGRID_122362|BIOGRID_122360 bait|prey|bait prey|bait|prey HGS GGA3 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15611048 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint)|MI:0471(mint) UniProt_81033|MINT_59801|MINT_31205 bait|bait|bait prey|prey|prey CDKN2A GGA3 MI:0055(fluorescent resonance energy transfer) 21517092 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_216313 bait prey VPS11 GGA3 MI:0096(pull down) 16996030 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_122361 bait prey UBC GGA3 MI:0114(x-ray crystallography)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0114(x-ray crystallography)|MI:0096(pull down)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 14660606,15701688,15966896,16135791,16497223,17116753,20484053,21139048,21890473,21906983,21963094,22053931,22505724,23000965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0914(association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_195203|BIOGRID_223741|BIOGRID_176207|BIOGRID_195204|BIOGRID_195205|BIOGRID_196790|BIOGRID_122139|BIOGRID_266255|BIOGRID_193981|BIOGRID_124707|BIOGRID_196789|BIOGRID_132825|BIOGRID_132826|BIOGRID_194110|BIOGRID_270212|BIOGRID_177950|BIOGRID_132824|BIOGRID_168580|BIOGRID_222069 prey|bait|bait|prey|prey|prey|bait|bait|bait|bait|prey|bait|bait|bait|bait|bait|prey|bait|bait bait|prey|prey|bait|bait|bait|prey|prey|prey|prey|bait|prey|prey|prey|prey|prey|bait|prey|prey

PPI - HINT Gene A Gene B PMID Method Quality UBC GGA3 14660606,15701688,15966896,20484053,15966896,15494413,15966896,14660606,17116753,16497223,15701688 0004,0096,0004,0096,0114,0096,0096,0096,0096,0096,0114 LC IGF2R GGA3 11390366,12032548,12060753,12032548,12032548,16977309,16977309,14567678 0004,0018,0004,0114,0004,0096,0428,0004 LC ARF6 GGA3 23143332,18199687,20848231,19327867 0096,0004,0096,0096 LC ARF1 GGA3 11950392,10747089,10747089 0096,0018,0096 LC RABEP1 GGA3 12505986,12505986,12858162,12858162,16473621,16473621 0018,0007,0114,0004,0114,0096 LC TMEM17 GGA3 26638075,26638075 1314,1313 HT HAUS4 GGA3 26344197 0401 HT TMEM17 GGA3 26638075,26638075 1314,1313 HT HAUS4 GGA3 26344197 0401 HT UBC GGA3 14660606,15701688,15966896,20484053,15966896,15494413,15966896,14660606,17116753,16497223,15701688 0004,0096,0004,0096,0114,0096,0096,0096,0096,0096,0114 LC IGF2R GGA3 11390366,12032548,12060753,12032548,12032548,16977309,16977309,14567678 0004,0018,0004,0114,0004,0096,0428,0004 LC ARF6 GGA3 23143332,18199687,20848231,19327867 0096,0004,0096,0096 LC ARF1 GGA3 11950392,10747089,10747089 0096,0018,0096 LC RABEP1 GGA3 12505986,12505986,12858162,12858162,16473621,16473621 0018,0007,0114,0004,0114,0096 LC HEL112 GGA3 15039775 0018 LC HGS GGA3 15611048 0018 LC UBB GGA3 15039775,15039775 0004,0018 LC UBC GGA3 16135791,15701688,15966896,15966896,15966896,15701688 0018,0096,0004,0114,0096,0114 LC IGF2R GGA3 11859375,11387475,11859375,16135791,12032548,12032548,12032548 0018,0018,0114,0018,0018,0114,0004 LC RAB5A GGA3 14665628 0018 LC M6PR GGA3 11859375,11387475 0114,0018 LC CDKN2A GGA3 21517092 0055 LC ARF3 GGA3 10749927,12221117 0018,0018 LC RPS27A GGA3 15039775 0018 LC UBA52 GGA3 15701688 0114 LC ARF1 GGA3 10747089,11301005,10747089 0018,0018,0096 LC RABEP1 GGA3 12505986,12505986,14665628,12858162,12858162,16473621,16473621 0018,0007,0018,0114,0004,0114,0096 LC AFTPH GGA3 14665628 0018 LC TSG101 GGA3 15039775 0018 LC VPS11 GGA3 16996030 0415 LC HAUS4 GGA3 26344197 0401 LC GGA3 GGA3 11859375,12032548,10814529,15701688 0114,0114,0018,0114 LC GGA3 VPS18 16996030,16996030,16996030 0415,0004,0096 LC GGA3 SYNRG 10814529 0018 LC GGA3 RNF11 15231748 0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9NZ52 P61204 GGA3 ARF3 0.309 10749927 Q9NZ52 P62331 GGA3 ARF6 0.309 18162163 Q9NZ52 Q8N726 GGA3 CDKN2A 0.309 21517092 Q9NZ52 Q9HCE1 GGA3 MOV10 0.126 22658674 Q9NZ52 Q9H6D7 GGA3 HAUS4 0.081 26344197 Q9NZ52 Q9H270 GGA3 VPS11 0.309 16996030 Q9NZ52 Q9NY15 GGA3 STAB1 0.309 15345724 Q9NZ52 O14964 GGA3 HGS 0.309 15611048 Q9NZ52 O43493 GGA3 TGOLN2 0.126 16977309 Q9NZ52 P0CG53 GGA3 UBB 0.309 20150893 Q9NZ52 P0CH28 GGA3 UBC 0.309 20150893 Q9NZ52 P20645 GGA3 M6PR 0.671 11387475,11859375 Q9NZ52 Q00610 GGA3 CLTC 0.309 11301005 Q9NZ52 Q14677 GGA3 CLINT1 0.309 12858162 Q9NZ52 Q7Z3U7 GGA3 MON2 0.376 18418388 Q9NZ52 Q96J02 GGA3 ITCH 0.21 25195858 Q9UJY5 Q9NZ52 GGA1 GGA3 0.583 14638859 Q9UMZ2 Q9NZ52 SYNRG GGA3 0.309 12858162 Q9NZ52 O18973 GGA3 RABGEF1 0.21 12505986 Q9NZ52 O88588 GGA3 PACS1 0.21 16977309 Q9NZ52 P0CG47 GGA3 UBB 0.454 15039775 Q9NZ52 Q6IPX1 GGA3 TBC1D3C 0.454 18199687 Q9NZ52 P36406 GGA3 TRIM23 0.236 unassigned1304 Q9NZ52 P84077 GGA3 ARF1 0.843 10747089,11950392,11301005 Q9NZ52 Q6VY07 GGA3 PACS1 0.765 16977309 Q9NZ52 Q8IZP1 GGA3 TBC1D3 0.454 18199687 Q9Y3C5 Q9NZ52 RNF11 GGA3 0.597 15231748,25195858 Q9NZ52 P0CG63 GGA3 UBI4 0.454 15039776 Q9NZ52 P08581 GGA3 MET 0.309 21664574 Q9NZ52 Q96BW1 GGA3 UPRT 0.236 unassigned1304 Q9NZ52 Q96CS7 GGA3 PLEKHB2 0.236 unassigned1304 Q9NZ52 Q99732 GGA3 LITAF 0.236 unassigned1304 Q9NZ52 Q15038 GGA3 DAZAP2 0.236 unassigned1304 Q9NZ52 Q6ZNH5 GGA3 ZNF497 0.236 unassigned1304 Q9NZ52 Q7Z4N8 GGA3 P4HA3 0.236 unassigned1304 Q9NZ52 Q86X19 GGA3 TMEM17 0.236 26638075 Q9NZ52 P57075 GGA3 UBASH3A 0.236 unassigned1304 Q9NZ52 O75865 GGA3 TRAPPC6A 0.236 unassigned1304 Q9NZ52 P56817 GGA3 BACE1 0.569 14567678,26053850 Q9NZ52 Q15276 GGA3 RABEP1 0.968 16473621,14665628,12505986,12858162 Q9NZ52 P0CG48 GGA3 UBC 0.941 15966896,15701688,16135791,15494413,20484053 Q9NZ52 P11717 GGA3 IGF2R 0.974 14567678,12060753,16135791,11387475,12032548,11390366,11859375,16977309 Q9NZ52 P62330 GGA3 ARF6 0.623 20848231,19327867,18199687 Q9NZ52 Q99523 GGA3 SORT1 0.21 11390366 Q9NZ52 Q99816 GGA3 TSG101 0.523 15039775 Q9P253 Q9NZ52 VPS18 GGA3 0.623 16996030 Q9UBU9 Q9NZ52 NXF1 GGA3 0.126 22658674 Q9UJY4 Q9NZ52 GGA2 GGA3 0.523 14638859 Q9NZ52 P46108 GGA3 CRK 0.21 21664574 Q9NZ52 P46934 GGA3 NEDD4 0.21 17116753 Q9NZ52 P42771 GGA3 CDKN2A 0.309 21517092 Q9NZ52 Q13571 GGA3 LAPTM5 0.21 17116753 Q9NZ52 P84080 GGA3 ARF1 0.671 11301005,10747089 Q9NZ52 P49951 GGA3 CLTC 0.309 11301005

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 HGS GGA3 MI:0045 experimental interaction detection MI:0461 interaction database MET GGA3 MI:0045 experimental interaction detection MI:0461 interaction database UBB GGA3 MI:0045 experimental interaction detection MI:0461 interaction database UBC GGA3 MI:0045 experimental interaction detection MI:0461 interaction database IGF2R GGA3 MI:0045 experimental interaction detection MI:0461 interaction database RAB5A GGA3 MI:0045 experimental interaction detection MI:0461 interaction database M6PR GGA3 MI:0045 experimental interaction detection MI:0461 interaction database TAF1 GGA3 MI:0045 experimental interaction detection MI:0461 interaction database CDKN2A GGA3 MI:0045 experimental interaction detection MI:0461 interaction database CRK GGA3 MI:0045 experimental interaction detection MI:0461 interaction database NEDD4 GGA3 MI:0045 experimental interaction detection MI:0461 interaction database BACE1 GGA3 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ARF3 GGA3 MI:0045 experimental interaction detection MI:0461 interaction database ARF6 GGA3 MI:0045 experimental interaction detection MI:0461 interaction database RPS27A GGA3 MI:0045 experimental interaction detection MI:0461 interaction database UBA52 GGA3 MI:0045 experimental interaction detection MI:0461 interaction database ARF1 GGA3 MI:0045 experimental interaction detection MI:0461 interaction database CLTC GGA3 MI:0045 experimental interaction detection MI:0461 interaction database LAPTM5 GGA3 MI:0045 experimental interaction detection MI:0461 interaction database CLINT1 GGA3 MI:0362 inference MI:0461 interaction database RABEP1 GGA3 MI:0045 experimental interaction detection MI:0461 interaction database TBC1D3C GGA3 MI:0045 experimental interaction detection MI:0461 interaction database PACS1 GGA3 MI:0045 experimental interaction detection MI:0461 interaction database MON2 GGA3 MI:0045 experimental interaction detection MI:0461 interaction database TMEM17 GGA3 MI:0045 experimental interaction detection MI:0461 interaction database TBC1D3 GGA3 MI:0045 experimental interaction detection MI:0461 interaction database CDKN2A GGA3 MI:0045 experimental interaction detection MI:0461 interaction database ITCH GGA3 MI:0045 experimental interaction detection MI:0461 interaction database SORT1 GGA3 MI:0045 experimental interaction detection MI:0461 interaction database TSG101 GGA3 MI:0045 experimental interaction detection MI:0461 interaction database TOLLIP GGA3 MI:0045 experimental interaction detection MI:0461 interaction database VPS11 GGA3 MI:0045 experimental interaction detection MI:0461 interaction database MOV10 GGA3 MI:0045 experimental interaction detection MI:0461 interaction database STAB1 GGA3 MI:0045 experimental interaction detection MI:0461 interaction database GGA3 VPS18 MI:0045 experimental interaction detection MI:0461 interaction database GGA3 NXF1 MI:0045 experimental interaction detection MI:0461 interaction database GGA3 RABGEF1 MI:0362 inference MI:0461 interaction database GGA3 GGA2 MI:0045 experimental interaction detection MI:0461 interaction database GGA3 GGA1 MI:0045 experimental interaction detection MI:0461 interaction database GGA3 SYNRG MI:0362 inference MI:0461 interaction database GGA3 RNF11 MI:0045 experimental interaction detection MI:0461 interaction database