Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 20 62398015 rs6011096 T C rs6011096 7.61E-04 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 C intron GWASdb_drug 20 62385479 rs7273624 G A rs7273624 5.17E-04 Oral cancers (chewing tobacco related) HPOID:0012290 DOID:1749|DOID:403 G intron GWASdb_trait 20 62398015 rs6011096 T C rs6011096 7.61E-04 Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 C intron GWASdb_trait 20 62401143 rs6089982 C T rs6089982 4.32E-04 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait 20 62409713 rs6062314 C T rs6062314 1.00E-07 Multiple sclerosis HPOID:0000096|HPOID:0001967|HPOID:0009741|HPOID:0008664|HPOID:0001150|HPOID:0005450|HPOID:0005652|HPOID:0005686|HPOID:0005789|HPOID:0100923|HPOID:0100925|HPOID:0006623|HPOID:0100861|HPOID:0002694|HPOID:0004979|HPOID:0003881|HPOID:0003991|HPOID:0003854|HPOID:0003933|HPOID:0004030|HPOID:0100899|HPOID:0002634 DOID:2377 T intron GWASdb_trait 20 62418337 rs2315656 G A rs2315656 4.00E-06 Obesity-related traits HPOID:0001513 DOID:9970 A intron GWASdb_trait 20 62421622 rs755017 A G rs755017 6.71E-09 Telomere length HPOID:0000118 NA G cds-synon GWASdb_trait 20 62422080 rs2281929 T C rs2281929 6.42E-04 Multiple complex diseases HPOID:0000118 NA C missense GWASdb_trait

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000130584.10 ZBTB46 614639