PTM - CPLM Gene Name UniProt ID Type Position Code UBE2M; UBC12 P61081 Acetylation 3 K UBE2M; UBC12 P61081 Ubiquitination 3 K UBE2M; UBC12 P61081 Ubiquitination 8 K UBE2M; UBC12 P61081 Ubiquitination 36 K UBE2M; UBC12 P61081 Ubiquitination 72 K UBE2M; UBC12 P61081 Ubiquitination 75 K UBE2M; UBC12 P61081 Ubiquitination 81 K UBE2M; UBC12 P61081 Ubiquitination 11 K UBE2M; UBC12 P61081 Ubiquitination 92 K UBE2M; UBC12 P61081 Ubiquitination 45 K

PTM - dbPAF Gene Name UniProt ID Position Type Species UBE2M; UBC12 P61081 172 Y Homo sapiens(Human) UBE2M; UBC12 P61081 177 Y Homo sapiens(Human) UBE2M; UBC12 P61081 20 T Homo sapiens(Human) UBE2M; UBC12 P61081 23 S Homo sapiens(Human) UBE2M; UBC12 P61081 28 S Homo sapiens(Human) UBE2M; UBC12 P61081 46 T Homo sapiens(Human) UBE2M; UBC12 P61081 50 S Homo sapiens(Human) UBE2M; UBC12 P61081 6 S Homo sapiens(Human) UBE2M; UBC12 P61081 86 Y Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA P61081 K3-ac Acetylation _____MIkLFsLkQQ P61081 R33-m1 Methylation KAsAAQLrIQkDINE P61081 K61-m2 Methylation PDDLLNFkLVICPDE P61081 R157-m1 Methylation AEVLQNNrRLFEQNV P61081 R166-m1 Methylation LFEQNVQrSMrGGyI P61081 R169-m1 Methylation QNVQrSMrGGyIGST P61081 R180-m1 Methylation IGSTyFErCLK____ P61081 S6-p Phosphorylation __MIkLFsLkQQKKE P61081 T20-p Phosphorylation EEESAGGtKGsSKKA P61081 S23-p Phosphorylation SAGGtKGsSKKAsAA P61081 S28-p Phosphorylation KGsSKKAsAAQLrIQ P61081 T46-p Phosphorylation NELNLPktCDIsFSD P61081 S50-p Phosphorylation LPktCDIsFSDPDDL P61081 Y172-p Phosphorylation QrSMrGGyIGSTyFE P61081 Y177-p Phosphorylation GGyIGSTyFErCLK_ P61081 K3-ub Ubiquitination _____MIkLFsLkQQ P61081 K8-ub Ubiquitination MIkLFsLkQQKKEEE P61081 K36-ub Ubiquitination AAQLrIQkDINELNL P61081 K45-ub Ubiquitination INELNLPktCDIsFS P61081 K61-ub Ubiquitination PDDLLNFkLVICPDE P61081 K72-ub Ubiquitination CPDEGFYkSGkFVFS P61081 K75-ub Ubiquitination EGFYkSGkFVFSFkV P61081 K81-ub Ubiquitination GkFVFSFkVGQGYPH P61081 K92-ub Ubiquitination GYPHDPPkVkCETMV P61081 K94-ub Ubiquitination PHDPPkVkCETMVYH

PTM - dbPTM UniProt ID Position Code Type Resources References P61081 1 M Acetylation Swiss-Prot 1010711 19608861;21940857 P61081 3 K Acetylation Swiss-Prot 1010711 19608861 P61081 50 S Phosphorylation Swiss-Prot 1010711 18669648 P61081 50 S Phosphorylation PhosphoELM.10011 18669648 P61081 3 K Ubiquitylation Phosphositeplus.1010730 21890473 P61081 36 K Ubiquitylation Phosphositeplus.1010730 21890473 P61081 75 K Ubiquitylation Phosphositeplus.1010730 21890473 P61081 8 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 P61081 81 K Ubiquitylation Phosphositeplus.1010730 21890473 P61081 92 K Ubiquitylation Phosphositeplus.1010730 21906983 P61081 3 K Acetylation Phosphositeplus.1010730 19608861 P61081 28 S Phosphorylation Phosphositeplus.1010730 21406692 P61081 50 S Phosphorylation Phosphositeplus.1010730 18669648 P61081 20 T Phosphorylation Phosphositeplus.1010730 20068230 P61081 86 Y Phosphorylation Phosphositeplus.1010730 17016520 P61081 3 K Acetylation HPRD 9.0 19608861 P61081 50 S Phosphorylation HPRD 9.0 18669648 P61081 20 T Phosphorylation HPRD 9.0 20068230 P61081 47 C S-nitrosylation dbSNO 1.0 21278135;19483679 P61081 65 C S-nitrosylation dbSNO 1.0 19483679 P61081 50 S Phosphorylation SysPTM 1.1 18669648

PTM - HPRD Symbol Position Code Type References UBE2M 0 K Acetylation 19608861 UBE2M 20 T Phosphorylation 20068230 UBE2M 3 K Acetylation 19608861 UBE2M 50 S Phosphorylation 18669648

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type P61081 50 S 18669648 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs P61081 1 N-acetylmethionine 21940857;23201271 P61081 3 N6-acetyllysine 19608861 P61081 50 Phosphoserine 18669648 P61081 169 Omega-N-methylarginine; alternate 24129315

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type UBE2M IPI00022597 K 3 ____MIaKLFSLKQ acetylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 9040 114504 - K Neddylation 18274552 9040 114504 - K Ubiquitination 21963094 9040 114504 - K Ubiquitination 21139048 9040 114504 - K Ubiquitination 21890473 9040 114504 - K Ubiquitination 21906983 9040 114504 - K Ubiquitination 21853274 9040 114504 - K Ubiquitination 22505724 9040 114504 - K FAT10ylation 22797925 9040 114504 - K Neddylation 23267066 9040 114504 - K Ubiquitination 23000965 9040 114504 - K Neddylation 24654937 9040 114504 - K Ubiquitination 25147182 9040 114504 - K Neddylation 19245792 9040 114504 - K Neddylation 23824602 9040 114504 - K Neddylation 18247557

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID UBE2M Homo sapiens (Human) 3; 81; 36; 8; 92; 72; 75 "3,MIKLFSLKQ; 81,KFVFSFKVGQGYP; 36,AQLRIQKDINELN; 8,IKLFSLKQQKKEE; 92,YPHDPPKVKCETM; 72,PDEGFYKSGKFVF; 75,GFYKSGKFVFSFK" "3:21890473; 81:21890473; 36:21890473; 8:21890473,21906983; 92:21906983; 72:21890473; 75:21890473"