| Peroxisome proliferator activated receptor gamma | Successful target | PPARgamma;PPAR-gamma;Transcription factor PPAR gamma receptor | Inflammation;Renal cell carcinoma;Ischemic heart disease;Bladder cancer;Atherosclerosis;Multiple sclerosis;Ulcerative colitis;Insulin resistance;Obesity;Asthma;Chronic inflammatory diseases;Inflammatory bowel disease;Pancreatic cancer;Diabetes mellitus;Crohn's disease;Atopic dermatitis;Testicular cancer;Autoimmune diseases;Adrenocorticotrophic hormone-secreting pituitary tumor;Psoriasis;Thyroid follicular carcinoma | Rosiglitazone + simvastatin;GW-409544;DS-6930;Troglitazone;Imiglitazar;LY-929;CS-038;TESAGLITAZAR;Pioglitazone;Thiazolidinedione;EV-077;GED-0507-34-Levo;CS-7017;CS-7017;Englitazone sodium;Research programme: peroxisome proliferator-activated receptor gamma agonist, Omeros;IDR-105;E-3030;OMS405;CLX-0921;Naveglitazar;Reglixane;Glitazone;T3D-959;Rosiglitazone;Oxeglitazar;Lobeglitazone;Netoglitazone;Ciglitazone;DB 959;MBX-2044;FK-614;Sodelglitazar;Rosiglitazone + metformin;GSK-677954;YM-440;ZYH-1;AVE-0847;DSP-8658;DSP-8658;ONO-5129;Rosiglitazone XR;Genistein;MBX-102;Rivoglitazone;Indeglitazar;MK-767 (KRP-297) | 3-(5-methoxy-1H-indol-3-yl)propanoic acid;(9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid;(9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid;TESAGLITAZAR;(2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid;2-chloro-5-nitro-N-phenylbenzamide;(2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid;(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid;YM-440 | |
| mRNA of PPAR-gamma | Clinical trial target | Peroxisome proliferatoractivated receptor gamma (mRNA);PPARgamma (mRNA);Nuclear receptor subfamily 1 group C member 3 (mRNA);PPARG (mRNA) | Diabetes mellitus type 1;Metabolic disorders;Hyperlipidemia;Under research | TESAGLITAZAR;Ragaglitazar;FARGLITAZAR;METAGLIDASEN;MURAGLITAZAR | BRL-48482;(E)-6-Nitrooctadec-5-enoic Acid;(E)-12-Nitrooctadec-12-enoic Acid;L-165461;(E)-13-Nitrooctadec-12-enoic Acid;(E)-9-Nitrohexadec-9-enoicAcid;SB-213068;CHLOROCYCLINONE A;GNF-PF-2893;CHLOROCYCLINONE D;TESAGLITAZAR;(E)-10-nitrooctadec-9-enoic acid;L-Tryptophan-L-asparagine;CHLOROCYCLINONE B;L-Tryptophan-L-2-aminoadipic acid;(9Z,12E)-12-nitrooctadeca-9,12-dienoic acid;(E)-9-nitrooctadec-9-enoic acid;2-chloro-5-nitro-N-(pyridin-4-yl)benzamide;L-796449;Ragaglitazar;FARGLITAZAR;KRP-297;L-Tryptophan-L-leucine;GNF-PF-3037;METAGLIDASEN;L-Tryptophan-L-arginine;L-Tryptophan-L-glutamine;MURAGLITAZAR;PLOGLITAZONE;L-Tryptophan-L-aspartic acid;(E)-10-Nitrohexadec-9-enoic Acid;PD-068235;(E)-5-Nitrooctadec-5-enoic Acid;GW-9662;CHLOROCYCLINONE C | |