PTM - CPLM Gene Name UniProt ID Type Position Code VHL P40337 Sumoylation 171 K VHL P40337 Ubiquitination 196 K VHL P40337 Ubiquitination 171 K

PTM - dbPAF Gene Name UniProt ID Position Type Species VHL P40337 100 T Homo sapiens(Human) VHL P40337 105 T Homo sapiens(Human) VHL P40337 111 S Homo sapiens(Human) VHL P40337 112 Y Homo sapiens(Human) VHL P40337 168 S Homo sapiens(Human) VHL P40337 175 Y Homo sapiens(Human) VHL P40337 183 S Homo sapiens(Human) VHL P40337 185 Y Homo sapiens(Human) VHL P40337 202 T Homo sapiens(Human) VHL P40337 33 S Homo sapiens(Human) VHL P40337 38 S Homo sapiens(Human) VHL P40337 43 S Homo sapiens(Human) VHL P40337 68 S Homo sapiens(Human) VHL P40337 72 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA P40337 R79-m1 Methylation sQVIFCNrsPRVVLP P40337 S33-p Phosphorylation EEDGGEEsGAEEsGP P40337 S38-p Phosphorylation EEsGAEEsGPEEsGP P40337 S43-p Phosphorylation EEsGPEEsGPEELGA P40337 S68-p Phosphorylation PVLRSVNsREPsQVI P40337 S72-p Phosphorylation SVNsREPsQVIFCNr P40337 S80-p Phosphorylation QVIFCNrsPRVVLPV P40337 T100-p Phosphorylation GEPQPYPtLPPGtGR P40337 T105-p Phosphorylation YPtLPPGtGRRIHsy P40337 S111-p Phosphorylation GtGRRIHsyRGHLWL P40337 Y112-p Phosphorylation tGRRIHsyRGHLWLF P40337 S168-p Phosphorylation RCLQVVRsLVkPENy P40337 Y175-p Phosphorylation sLVkPENyRRLDIVR P40337 S183-p Phosphorylation RRLDIVRsLyEDLED P40337 Y185-p Phosphorylation LDIVRsLyEDLEDHP P40337 T202-p Phosphorylation QkDLERLtQERIAHQ P40337 K171-sm Sumoylation QVVRsLVkPENyRRL P40337 K159-ub Ubiquitination TLPVYTLkERCLQVV P40337 K171-ub Ubiquitination QVVRsLVkPENyRRL P40337 K196-ub Ubiquitination EDHPNVQkDLERLtQ

PTM - dbPTM UniProt ID Position Code Type Resources References P40337 171 K Sumoylation Phosphositeplus.1010730 20300531 P40337 196 K Ubiquitylation Phosphositeplus.1010730 21890473 P40337 111 S Phosphorylation Phosphositeplus.1010730 22071692 P40337 33 S Phosphorylation Phosphositeplus.1010730 20637892 P40337 38 S Phosphorylation Phosphositeplus.1010730 20637892 P40337 43 S Phosphorylation Phosphositeplus.1010730 20637892 P40337 68 S Phosphorylation Phosphositeplus.1010730 16847331;20637892 P40337 72 S Phosphorylation Phosphositeplus.1010730 16847331;20637892 P40337 185 Y Phosphorylation Phosphositeplus.1010730 20562096

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 7428 113269 - K Ubiquitination 20844582 7428 113269 - K Neddylation 15060148 7428 113269 - K Ubiquitination 21139048 7428 113269 - K Ubiquitination 21890473 7428 113269 - K Sumoylation 20300531 7428 113269 - K Ubiquitination 21625219 7428 113269 - K Neddylation 18323857 7428 113269 - K Ubiquitination 20802534 7428 113269 - K Ubiquitination 24145437 7428 113269 - K Ubiquitination 23387829

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID VHL Homo sapiens (Human) 114 "114,DHPNVQKDLERLT" 114:21890473 VHL Homo sapiens (Human) 155 "155,DHPNVQKDLERLT" 155:21890473 VHL Homo sapiens (Human) 196 "196,DHPNVQKDLERLT" 196:21890473 VHL Homo sapiens (Human) 155 "155,DHPNVQKDLERLT" 155:21890473 VHL Homo sapiens (Human) 143 "143,DHPNVQKDLERLT" 143:21890473 VHL Homo sapiens (Human) 114 "114,DHPNVQKDLERLT" 114:21890473