PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus PRO1670 USP15 17353931 intact exp BMPR1B USP15 24850914 biogrid exp GP G G GP GP G G GP G GP P GP G GP GP GP GP G P GP P GP GP GP GP GP G PLA2G2A USP15 22118674 biogrid exp G GP G GP P G G GP P G G G G GP GP GP GP GP GP G GP GP G GP GP G ID1 USP15 26496610 biogrid,intact exp G GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G PRPF31 USP15 19615732 biogrid,intact exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HUWE1 USP15 25147182 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SMAD3 USP15 21947082,22344298 biogrid exp G GP G G G GP G G G G G G GP GP G G GP G GP G GP G G G G G G G G SHB USP15 20007894 i2d exp G GP G G G GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G LRRC15 USP15 19615732 biogrid,intact exp G GP G G GP GP G G GP G GP GP G G G GP GP G GP G GP GP GP GP P GP GP G OBFC1 USP15 26186194 biogrid exp G G G G G GP G G GP G GP G G G G GP GP G G G GP GP GP G GP G G GP G SOX2 USP15 23667531 biogrid exp P G P GP G GP G P P GP P GP GP P G P GP P GP P GP GP G SMAD1 USP15 21947082,22344298 biogrid exp G G G G G G G G GP G G G G G G G G G G G G G G G G G G GP G KRT35 USP15 19615732 biogrid,intact exp G LSM2 USP15 19615732 biogrid,intact exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G FABP4 USP15 19615732 biogrid,intact exp G G G GP G G GP G G GP G G G G G G G G G G G G G G G GRK5 USP15 22952844 biogrid exp G GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G USP15 LSM4 19615732 biogrid,intact exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM63 USP15 22626734 biogrid exp G G G G PGAM2 USP15 19615732 biogrid,intact exp P G P P P GP G GP FERMT3 USP15 26496610 biogrid,intact exp G G G G G G G G G G G G G G G G OTUB1 USP15 22626734 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UCHL3 USP15 22626734 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TMEM132A USP15 26496610 biogrid,intact exp G GP G G G GP G G GP G GP P G G G GP GP G G G G G GP GP GP G GP GP G USP15 MYH4 19615732 biogrid,intact exp P G P P GP G NOTCH1 USP15 23022380 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CUL3 USP15 21145461 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PRPF4 USP15 19615732 biogrid,intact exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SMURF2 USP15 22344298 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G STAM USP15 22626734 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP G GP GP G FN1 USP15 19738201 biogrid,intact exp G G G G GP GP G G GP G GP GP G G G G GP GP G G GP G G G G G G G G TRIM46 USP15 23105109 biogrid exp G GP G G G GP G G GP G GP G GP G G GP GP P GP G P GP GP GP GP G G GP G SHFM1 USP15 24811749 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PSMD7 USP15 26186194,19615732 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G BAG6 USP15 26496610 biogrid,intact exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UCHL1 USP15 22626734 biogrid exp G G G G G GP G G GP G GP G G G G G GP G GP G G G G G G G G GP G ZMYM2 USP15 22939629 biogrid exp G GP G G GP GP G G GP G GP G G GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RNF20 USP15 24526689 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G STK33 USP15 22451720 biogrid exp GP G GP G P G GP P P P GP GP GP GP G P P P G GP P P GP G ECHS1 USP15 26186194 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TGFBR1 USP15 22344298,24850914,23973329 biogrid exp G G G G GP GP G G GP G GP GP GP G G GP GP G G G G G G G GP G GP G G USP15 TRAF6 20622874 biogrid exp G GP G G GP G G G GP G GP GP GP G G GP G GP G G GP GP GP G GP GP GP GP G BMPR1A USP15 24850914 biogrid exp G GP G P GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G SMAD7 USP15 22344298 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP P G SMAD4 USP15 21947082,22344298 biogrid exp G GP G G GP GP G G GP G GP GP GP G G GP GP GP GP G GP GP GP G GP GP GP GP G RNF144B USP15 23105109 biogrid exp G GP G G G GP G G GP G GP GP GP G G GP GP GP GP G GP G G G GP G G GP G NUSAP1 USP15 22863883 biogrid exp G GP G GP G G G GP GP G G GP G GP G G GP G GP P GP GP GP GP GP GP G HMG20B USP15 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBA52 USP15 21209336 dip exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SPDL1 USP15 25416956 biogrid,intact exp G P G GP P G GP G P P P GP G GP GP GP P P P GP GP GP GP GP GP TRIM54 USP15 22626734 biogrid exp P P G P P P P G P GP GP P P DDX58 USP15 26061460 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G TRAF4 USP15 23973329 biogrid exp G GP G GP G GP G GP GP GP G G GP GP G GP G GP G GP P GP G GP GP G ATL3 USP15 26496610 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYH2 USP15 19615732 biogrid,intact exp G G G G G GP G G G KRT33B USP15 19615732 biogrid,intact exp P P CCDC57 USP15 25416956 biogrid,intact exp G GP G G GP GP G G GP G GP GP GP P G GP GP GP GP G GP P GP GP GP GP GP GP ALDOA USP15 19615732 biogrid,intact exp G GP G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP GP GP GP G GP GP GP G SENP3 USP15 22626734 biogrid exp G GP G G G GP G G GP G GP GP G G G GP GP G GP G GP G GP GP GP G GP GP G BRAP USP15 23105109 biogrid exp P G GP P G P P P P P G GP P P G GP P GP GP GP P P GP SNUPN USP15 26186194 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G VSIG8 USP15 19615732 biogrid,intact exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G KRT81 USP15 19615732 biogrid,intact exp G UBC USP15 19373254,25527291,22626734,24850914,20622874,16005295 biogrid,mint,intact exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G NTRK1 USP15 25921289 biogrid exp P P G P P P P P P P P P P P P P P KRT31 USP15 19615732 biogrid,intact exp G G G GP G P P P G P GP G P P GP G GP P G HIST2H2AC USP15 24526689 biogrid exp P P P P P P P P P P P P P P P P P P P P TRIM25 USP15 24399297 biogrid exp G GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G WAPAL USP15 22939629 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SHC1 USP15 19380743 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MKNK2 USP15 26496610 biogrid,intact exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIM74 USP15 23105109 biogrid exp ADSL USP15 19615732 biogrid,intact exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ACVR1 USP15 24850914 biogrid exp G GP G G G GP G G GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G CARD9 USP15 25416956 biogrid,intact exp G GP P P G P P GP P P PLOD2 USP15 22863883 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G BIRC2 USP15 23524849 biogrid,intact exp G GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP G GP GP GP GP GP GP G RBCK1 USP15 23105109 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G BIRC3 USP15 23524849 biogrid,intact exp G G GP G G GP P GP G GP G GP G GP P G GP GP GP GP GP UGP2 USP15 22863883 biogrid exp G GP G G G GP G G G G GP GP G G G G GP G G G GP G GP GP G G G GP G PSMB9 USP15 26186194 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G NXF1 USP15 22658674 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HIST2H2BE USP15 24526689 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KRT34 USP15 19615732 biogrid,intact exp P P JOSD1 USP15 22626734 biogrid exp G GP G G G GP G G GP G GP G GP G G GP GP GP GP G GP GP GP GP GP G GP G G USP15 USP15 23606334,22001210 biogrid,intact exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MED4 USP15 25281560 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CKB USP15 19615732 biogrid,intact exp G G G G G GP G G GP G G G G G G G GP G G G G GP G GP G G GP G G CFLAR USP15 17353931 intact exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G LSM8 USP15 19615732 biogrid,intact exp G GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G PHF7 USP15 23105109 biogrid exp GP G G GP P G G P G GP GP GP GP G P GP GP GP G P GP GP GP P P GP G RNF40 USP15 19615732,24526689 biogrid,intact exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KRT85 USP15 19615732 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G CD40 USP15 17353931 biogrid,intact exp G G G G G G G G G G G G G GP G G G G G G G G G G G GP G G G USP28 USP15 22626734 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2G2 USP15 17353931 biogrid,intact exp G GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP G G GP GP GP GP G SGTB USP15 26496610 biogrid,intact exp G G G G G GP G G GP G G G G G GP G G G G GP P G G GP G P G TRPV5 USP15 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G SMAD6 USP15 24850914 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G CALML3 USP15 19615732 biogrid,intact exp G GP G G GP GP G G GP G GP GP GP G G GP GP G GP G P GP GP GP GP P GP GP G USP15 TRIM17 23105109 biogrid exp P P P P P P P P P P P P P P P P GP TRIM5 USP15 23105109 biogrid exp G GP G GP P G G GP GP GP GP GP G GP P GP GP G GP GP GP P GP GP GP P G RNF126 USP15 23105109 biogrid exp G G G G GP GP G G GP G GP G GP GP G GP GP GP P G GP GP G G GP GP GP GP G EEF2KMT USP15 26186194 biogrid exp P P P P P P P P P P P P PHB2 USP15 17353931 biogrid,intact exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SMURF1 USP15 23184937 biogrid exp G GP G G GP GP G G GP G GP G GP G G G GP GP G G GP G G G G GP G GP G NPM1 USP15 23402259 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G LSM6 USP15 19615732 biogrid,intact exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PRPF3 USP15 19615732 biogrid,intact exp G GP G G G GP G G GP G GP G GP G G GP GP GP GP G GP GP GP GP GP G GP GP BCAT1 USP15 26186194 biogrid exp G GP G G GP GP G G GP G GP G G G GP GP GP GP G GP GP GP G GP GP GP G URM1 USP15 21209336 dip exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G USP15 MAD1L1 25416956 biogrid,intact exp G P G P GP G P P GP GP GP G GP GP P P G P GP P GP GP GP P GP LMNA USP15 22412018 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G FAM107A USP15 17353931 intact exp G G G G G G GP G GP G G G G G G G G GP GP G G G GP G G SELENBP1 USP15 19615732 biogrid,intact exp G G G G GP G G G GP G GP GP GP G G GP G G G G G GP GP G GP GP GP GP G TUT1 USP15 19615732 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G LGALS7, LGALS7B USP15 19615732 biogrid,intact exp ME2 USP15 17353931 intact exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2S USP15 20622874 biogrid exp G G G G G G G G GP G G G GP G G G G G G G G G G G GP G FHL1 USP15 21219870 biogrid exp G G G G G G G G GP G GP G GP G G G G GP GP G GP G G GP G G G G G SMAD2 USP15 21947082,22344298 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SORT1 USP15 26496610 biogrid,intact exp G G G G GP GP G G GP G GP G GP G G G GP G GP G GP G G GP G G G GP G DFFA USP15 17353931 biogrid,intact exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CSTF1 USP15 19615732 biogrid,intact exp G P G GP P P P P P P G GP P GP P P GP P GP GP P P GP TERF2 USP15 20811636 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ZC3H13 USP15 22939629 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G USP14 USP15 22626734 biogrid exp, ortho G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G USP11 USP15 19615732 innatedb,biogrid exp, ortho G GP G G G GP G G GP G GP G G G G G GP G G G G G G G G G G GP G USP51 USP15 22626734 biogrid exp, ortho G GP G G GP GP G G P G GP P GP G P GP GP GP G GP GP P P GP P GP USP20 USP15 22626734, 23023127 biogrid exp, ortho, pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G USP8 USP15 22626734, 23023127 biogrid exp, ortho, pred G GP G G GP GP G G GP G GP G GP G G GP GP G GP G GP GP G GP GP G GP GP G BAP1 USP15 22626734, 23023127 biogrid exp, pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G YOD1 USP15 22626734, 23023127 biogrid exp, pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G SART3 USP15 24984263,19615732,24526689, 25402006 biogrid exp, pred G GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G USP33 USP15 22626734, 23023127 biogrid exp, pred G GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G PSMD11 USP15 19615732, 21836163 biogrid,intact exp, pred G GP G G GP GP G G GP G GP G GP G G G GP G G G GP G G G G G G GP G TRIM21 USP15 25416956,23105109, 23023127 biogrid,intact exp, pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G USP4 USP15 22626734,22706160, 23023127 biogrid exp, pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP G GP GP G CAND1 USP15 21145461, 21836163 biogrid exp, pred G GP G G G G G G GP G GP GP G G G GP G GP G G G G GP GP GP G G GP G USP10 USP15 22939629, 25402006, 23023127 biogrid exp, pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PPIH USP15 19615732, 25402006 biogrid,intact exp, pred G GP G G GP GP G G GP GP P GP GP G GP GP GP GP G GP G GP G GP GP GP GP G SENP8 USP15 22626734, 21836163 biogrid exp, pred P G P GP G G P G GP P P P P P GP P G P GP P GP GP P P GP CUL4B USP15 21145461, 21836163 biogrid exp, pred G GP G G GP GP G G GP G GP GP G GP G GP GP G GP G GP GP GP GP GP GP GP GP G TCEAL4 USP15 26496610, 25402006 biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G USP7 USP15 22626734, 23023127 biogrid exp, pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G USP21 USP15 22626734, 23023127 biogrid exp, pred G GP G G G GP G G GP G GP GP GP G G GP GP G GP G GP GP GP G GP G GP GP G COPS5 USP15 21145461, 21836163 biogrid exp, pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MEPCE USP15 19615732, 25402006 biogrid,intact exp, pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G YWHAE USP15 ortho G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MDM2 USP15 ortho G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CYLD USP15 23023127 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP AZIN1 USP15 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G NRBP1 USP15 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TCEAL3 USP15 25402006 pred G G G G GP GP G G GP G GP G GP G G G GP GP G G GP GP G G G G G GP G SNIP1 USP15 21836163 pred G GP G G GP GP G G GP G GP GP GP G G GP GP G GP G GP G GP GP GP G GP GP G TCEAL2 USP15 25402006 pred G GP G GP G G GP G GP P GP GP G GP GP GP GP G P G GP P GP G GP GP G PSMG2 USP15 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G MLF1 USP15 21836163 pred G GP G P GP G G GP G GP GP P G GP GP GP GP G P GP GP G GP P GP GP G USP44 USP15 23023127 pred P P P P P P P P P P P GP G P P P P P P GP SF3B3 USP15 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G USP17L2 USP15 23023127 pred P P P P P P P P P P P P P P P P P P MAPKAPK5 USP15 21836163 pred G GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP UBD USP15 21836163 pred P P P P P P P P P P P P P P P P P P P P RNF135 USP15 23023127 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G PMF1 USP15 21836163 pred G GP G G G GP G G GP G GP G GP G G G GP G G G G GP G G G G GP GP G USP5 USP15 23023127, 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G USP39 USP15 25402006 pred G G G G G G G G G G G G G G G G G G G G G G TCEAL5 USP15 25402006 pred P P P P P P P P P P PSMC6 USP15 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G EIF3K USP15 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G DTL USP15 21836163 pred P G GP P G P P P G P GP P P P P G G G GP COPS6 USP15 21836163 pred G GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G PSMD13 USP15 21836163 pred G GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G BRCC3 USP15 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G EIF3E USP15 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G CUL1 USP15 21836163 pred G G G G G GP G G GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP GP GP GP G USP15 UCHL5 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CSN1S1 USP15 21836163 pred G G C1orf43 USP15 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G EIF3D USP15 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G COPS8 USP15 21836163 pred G G G G G GP G G G G G G GP G G G GP G G G G G G G G G G GP G PSMD3 USP15 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SAP130 USP15 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GPS1 USP15 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G COPS3 USP15 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TCEAL1 USP15 25402006 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G PSMD8 USP15 21836163 pred G GP G G G GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ABCA5 USP15 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMD14 USP15 21836163 pred G GP G G GP GP G G GP G GP GP GP G G GP GP GP GP G GP G G GP GP G GP GP G OAZ3 USP15 21836163 pred P G GP P P P P P P P P P GP P GP GP GP P P P GP COPS2 USP15 21836163 pred G GP G G G GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ADRM1 USP15 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBAP2L USP15 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G USP15 USP3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G USP22 USP15 23023127 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MYSM1 USP15 23023127 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UHRF2 USP15 23023127 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CRCT1 USP15 21836163 pred G G UBA3 USP15 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G USP15 ARIH1 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMA1 USP15 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMD4 USP15 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G TOLLIP USP15 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G UBE2Q1 USP15 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G BARD1 USP15 23023127 pred P G GP P GP P P P GP G GP P G P P GP P GP P GP GP GP G USP12 USP15 23023127 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMD6 USP15 21836163 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G PSMD10 USP15 21836163 pred G G G G G GP G G GP G G G GP GP G GP GP GP GP G GP GP GP G GP G GP GP G RBX1 USP15 21836163 pred G G G G G GP G G G G G G GP G G G GP G GP G GP GP G G G G G GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9Y4E8 anti tag coimmunoprecipitation 21209336 - C 15 Q9Y4E8 P62987 deubiquitinase assay 21209336 - X 2 Q9Y4E8 A0A024R8C7 anti tag coimmunoprecipitation 21209336 physical association X 2 Q9Y4E8 A0A024R8C7 anti tag coimmunoprecipitation 21209336 physical association X 2 Q9Y4E8 cross-linking study 19738201 association C 402 Q9Y4E8 anti tag coimmunoprecipitation 24811749 association C 66 Q9H368 Q9Y4E8 anti bait coimmunoprecipitation 17353931 physical association X 2 Q9Y4E8 P23368 anti bait coimmunoprecipitation 17353931 physical association X 2 Q9Y4E8 P25942 anti bait coimmunoprecipitation 17353931 physical association X 2 Q9Y4E8 P60604 anti bait coimmunoprecipitation 17353931 physical association X 2 Q9Y4E8 Q99623 anti bait coimmunoprecipitation 17353931 physical association X 2 Q9Y4E8 anti tag coimmunoprecipitation 23524849 association C 20 Q9Y4E8 anti tag coimmunoprecipitation 23524849 association C 18 Q9Y4E8 anti tag coimmunoprecipitation 19615732 physical association C 32 Q96EA4 Q9Y4E8 two hybrid prey pooling approach 25416956 physical association X 2 Q96EA4 Q9Y4E8 two hybrid array 25416956 physical association X 2 Q96EA4 Q9Y4E8 validated two hybrid 25416956 physical association X 2 P19474 Q9Y4E8 two hybrid prey pooling approach 25416956 physical association X 2 P19474 Q9Y4E8 two hybrid array 25416956 physical association X 2 P19474 Q9Y4E8 validated two hybrid 25416956 physical association X 2 Q9Y6D9 Q9Y4E8 two hybrid prey pooling approach 25416956 physical association X 2 Q9Y6D9 Q9Y4E8 two hybrid array 25416956 physical association X 2 Q9Y6D9 Q9Y4E8 validated two hybrid 25416956 physical association X 2 P0CG48 Q9Y4E8 enzymatic study 19373254 deubiquitination reaction X 2 Q9Y4E8 O00273 anti bait coimmunoprecipitation 17353931 physical association X 2 Q9Y4E8 O95990 anti bait coimmunoprecipitation 17353931 physical association X 2 Q9Y4E8 A0A024R3Z7 anti bait coimmunoprecipitation 17353931 physical association X 2 Q9Y4E8 Q9Y4E8 molecular sieving 22001210 direct interaction Y 1 Q9Y4E8 Q9Y4E8 molecular sieving 22001210 direct interaction Y 1 Q9Y4E8 Q9Y4E8 molecular sieving 22001210 physical association Y 1 Q9Y4E8 Q9Y4E8 x-ray crystallography 22001210 direct interaction Y 1 Q9Y4E8 Q9Y4E8 x ray scattering 22001210 direct interaction Y 1 Q9Y4E8 Q2TAC2 two hybrid prey pooling approach 25416956 physical association X 2 Q9Y4E8 Q2TAC2 two hybrid array 25416956 physical association X 2 Q9Y4E8 Q2TAC2 validated two hybrid 25416956 physical association X 2 A0A024R8F1 Q9Y4E8 two hybrid prey pooling approach 25416956 physical association X 2 A0A024R8F1 Q9Y4E8 two hybrid array 25416956 physical association X 2 A0A024R8F1 Q9Y4E8 validated two hybrid 25416956 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B DFFA USP15 MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_148302|BIOGRID_83562 bait|bait prey|prey SMURF1 USP15 MI:0004(affinity chromatography technology) 23184937 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_248749 bait prey KRT81 USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_119559 prey|prey bait|bait LRRC15 USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_120809 prey|prey bait|bait TRIM63 USP15 MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_223009 bait prey RNF40 USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0096(pull down)|MI:0004(affinity chromatography technology) 19615732,24526689 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid)|(biogrid) UniProt_100662|BIOGRID_307684|BIOGRID_120097 prey|prey|prey bait|bait|bait RNF144B USP15 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248208 prey bait LMNA USP15 - 22412018 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_280449 bait prey MEPCE USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_120575 prey|prey bait|bait SART3 USP15 MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down) 19615732,24526689 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_121757|BIOGRID_307686|BIOGRID_307685|BIOGRID_307687 bait|bait|prey|prey prey|prey|bait|bait TGFBR1 USP15 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22344298,23973329 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_201546|BIOGRID_310205 bait|bait prey|prey RNF126 USP15 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248205 prey bait USP28 USP15 MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_223123 bait prey SELENBP1 USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_119999 prey|prey bait|bait KRT85 USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_119561 prey|prey bait|bait UBE2G2 USP15 MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_149490|BIOGRID_83004 bait|bait prey|prey LGALS7 USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_119566 prey|prey bait|bait SMAD3 USP15 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21947082,22344298 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_164919|BIOGRID_201542|BIOGRID_164915|BIOGRID_164913 prey|bait|bait|bait bait|prey|prey|prey HIST2H2BE USP15 MI:0096(pull down)|MI:0096(pull down) 24526689 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_307678|BIOGRID_307677 bait|bait prey|prey NAA38 USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_120469 prey|prey bait|bait FHL1 USP15 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21219870 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_198016|BIOGRID_198015 bait|prey prey|bait CALML3 USP15 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119373|UniProt_100662 prey|prey bait|bait WAPAL USP15 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_237621 prey bait PRPF4 USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid)|(biogrid) UniProt_100662|BIOGRID_121756|BIOGRID_120013 prey|bait|prey bait|prey|bait NPM1 USP15 MI:0004(affinity chromatography technology) 23402259 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_274615 bait prey SHC1 USP15 MI:0004(affinity chromatography technology) 19380743 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_219789 bait prey SOX2 USP15 MI:0004(affinity chromatography technology) 23667531 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_275142 bait prey USP15 MYH4 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_119594 bait|bait prey|prey USP15 LSM4 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_120349 bait|bait prey|prey USP15 TRIM17 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248203 bait prey USP15 TRAF6 MI:0415(enzymatic study) 20622874 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_165046 bait prey USP20 USP15 MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_223092 prey bait PGAM2 USP15 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119644|UniProt_100662 prey|prey bait|bait KRT33B USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_119555 prey|prey bait|bait FABP4 USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_119469 prey|prey bait|bait USP33 USP15 MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_223100 prey bait TRIM25 USP15 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 24399297 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_310094|BIOGRID_310093|BIOGRID_310096|BIOGRID_310080 prey|bait|prey|bait bait|prey|bait|prey TRIM46 USP15 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248206 prey bait TRIM74 USP15 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248209 prey bait FAM107A USP15 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_145944 bait prey PSMD11 USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_119741 prey|prey bait|bait TRIM5 USP15 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248207 prey bait TRAF4 USP15 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 23973329 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_310172|BIOGRID_310173 prey|bait bait|prey BRAP USP15 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_248152|BIOGRID_248201|BIOGRID_248150 bait|prey|bait prey|bait|prey BIRC3 USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 23524849 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association) (intact)|(biogrid) UniProt_130010|BIOGRID_272930 bait|bait prey|prey TRIM21 USP15 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248200 prey bait CSTF1 USP15 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119423|UniProt_100662 prey|prey bait|bait PLA2G2A USP15 MI:0415(enzymatic study) 22118674 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_160299 prey bait BAP1 USP15 MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_223104 prey bait VSIG8 USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_120882 prey|prey bait|bait SMAD1 USP15 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21947082,22344298 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_201540|BIOGRID_164911 bait|bait prey|prey TRIM54 USP15 MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_223050 bait prey PRPF31 USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_120374 prey|prey bait|bait MYH2 USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_119593 prey|prey bait|bait USP7 USP15 MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_223094 prey bait KRT31 USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_119552 prey|prey bait|bait UBE2S USP15 MI:0415(enzymatic study) 20622874 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_165031 prey bait SMAD7 USP15 MI:0004(affinity chromatography technology) 22344298 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_201544 bait prey HIST2H2AC USP15 MI:0096(pull down) 24526689 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_307679 bait prey PHF7 USP15 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248204 prey bait ALDOA USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_119344 prey|prey bait|bait TUT1 USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_120641 prey|prey bait|bait UCHL1 USP15 MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_223106 prey bait PSMD7 USP15 MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_121762 prey bait NOTCH1 USP15 MI:0004(affinity chromatography technology) 23022380 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_246663 bait prey USP10 USP15 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_237802 bait prey PLOD2 USP15 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_302013 prey bait KRT34 USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_119557 prey|prey bait|bait ME2 USP15 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_147273 bait prey PPIH USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_120162 prey|prey bait|bait CAND1 USP15 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_206466 bait prey BIRC2 USP15 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 23524849 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association) (biogrid)|(intact) BIOGRID_272910|UniProt_130011 bait|bait prey|prey CFLAR USP15 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_146444 bait prey ZMYM2 USP15 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_239619 prey bait COPS5 USP15 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_205644 bait prey ZC3H13 USP15 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_238821 prey bait USP8 USP15 MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_223098 prey bait CKB USP15 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119397|UniProt_100662 prey|prey bait|bait RNF20 USP15 MI:0096(pull down) 24526689 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_307683 prey bait USP21 USP15 MI:0415(enzymatic study)|MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_223099|BIOGRID_223080 prey|bait bait|prey LSM2 USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_120616 prey|prey bait|bait PRPF3 USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_120017 prey|prey bait|bait HMG20B USP15 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_239434 bait prey OTUB1 USP15 MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_223095 prey bait NUSAP1 USP15 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_301582 prey bait USP4 USP15 MI:0096(pull down)|MI:0415(enzymatic study) 22626734,22706160 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_200531|BIOGRID_223109 bait|prey prey|bait FN1 USP15 MI:0030(cross-linking study)|MI:0004(affinity chromatography technology) 19738201 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association) (intact)|(biogrid) UniProt_103099|BIOGRID_252844 bait|bait prey|prey SMURF2 USP15 MI:0004(affinity chromatography technology) 22344298 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_201545 prey bait USP51 USP15 MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_223093 prey bait USP14 USP15 MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_223102 prey bait RBCK1 USP15 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248202 prey bait LSM6 USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_120246 prey|prey bait|bait SMAD2 USP15 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21947082,22344298 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_201541|BIOGRID_164912 bait|bait prey|prey ADSL USP15 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100662|BIOGRID_119334 prey|prey bait|bait UCHL3 USP15 MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_223097 prey bait TERF2 USP15 MI:0004(affinity chromatography technology) 20811636 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_141049 bait prey KRT35 USP15 MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_119558 prey bait SENP3 USP15 MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_223108 prey bait UBC USP15 MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0096(pull down)|MI:0415(enzymatic study)|MI:0114(x-ray crystallography)|MI:0004(affinity chromatography technology)|MI:0114(x-ray crystallography)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0114(x-ray crystallography) 10,16005295,18781797,19373254,20622874,21139048,21890473,21963094,21987572,22118674,22626734,23000965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0204(deubiquitination reaction)|MI:0915(physical association)|MI:0204(deubiquitination reaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0204(deubiquitination reaction) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0471(mint)|(biogrid)|(intact)|(biogrid)|(biogrid)|MI:0471(mint) BIOGRID_166319|BIOGRID_163206|BIOGRID_190909|BIOGRID_174151|BIOGRID_162352|BIOGRID_160535|BIOGRID_127407|BIOGRID_165017|MINT_74134|BIOGRID_270022|UniProt_100030|BIOGRID_168312|BIOGRID_223107|MINT_43922 bait|bait|prey|bait|bait|bait|prey|prey|neutral component|bait|neutral component|bait|prey|neutral component prey|prey|bait|prey|prey|prey|bait|bait|neutral component|prey|neutral component|prey|bait|neutral component USP11 USP15 MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_121766 prey bait PHB2 USP15 MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_150866|BIOGRID_82713 bait|bait prey|prey UGP2 USP15 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304856 prey bait STAM USP15 MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_223103 prey bait SENP8 USP15 MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_223101 prey bait YOD1 USP15 MI:0415(enzymatic study) 22626734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_223105 prey bait CUL3 USP15 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_202014 bait prey CD40 USP15 MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_82456|UniProt_146874 bait|bait prey|prey GRK5 USP15 MI:0004(affinity chromatography technology) 22952844 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_218418 bait prey SMAD4 USP15 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21947082,22344298 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_201543|BIOGRID_164914 bait|bait prey|prey CUL4B USP15 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_203345 bait prey uniprotkb:(gene name) USP15 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_147199 bait prey

PPI - HINT Gene A Gene B PMID Method Quality PSMD11 USP15 19615732,19615732 0004,0007 HT DFFA USP15 17353931,17353931 0006,0004 HT PLOD2 USP15 22863883 0401 HT CFLAR USP15 17353931 0006 HT PRPF4 USP15 19615732,19615732 0004,0007 HT PRPF3 USP15 19615732,19615732 0004,0007 HT PPIH USP15 19615732,19615732 0004,0007 HT RNF40 USP15 19615732,19615732,24526689 0004,0007,0004 HT,LC KRT34 USP15 19615732,19615732 0004,0007 HT SNUPN USP15 26186194 0004 HT LSM8 USP15 19615732,19615732 0004,0007 HT FAM107A USP15 17353931 0006 HT ALDOA USP15 19615732 0007 HT CKB USP15 19615732 0007 HT FABP4 USP15 19615732,19615732 0004,0007 HT PGAM2 USP15 19615732,19615732 0004,0007 HT ME2 USP15 17353931 0006 HT CD40 USP15 17353931,17353931 0006,0004 HT CALML3 USP15 19615732,19615732 0004,0007 HT PSMB9 USP15 26186194 0004 HT SHC1 USP15 19380743 0004 HT ECHS1 USP15 26186194 0004 HT ADSL USP15 19615732,19615732 0004,0007 HT TGFBR1 USP15 23973329,24850914,22344298 0004,0004,0004 LC ID1 USP15 26496610,26496610 0007,0004 HT BAG6 USP15 26496610,26496610 0007,0004 HT LGALS7|LGALS7B USP15 19615732,19615732 0004,0007 HT PSMD7 USP15 19615732,26186194 0004,0004 HT USP11 USP15 19615732,19615732 0004,0007 HT PLK1 USP15 27173435 0676 HT BCAT1 USP15 26186194 0004 HT UBE2G2 USP15 17353931,17353931 0006,0004 HT LSM6 USP15 19615732,19615732 0004,0007 HT KRT85 USP15 19615732,19615732 0004,0007 HT CSTF1 USP15 19615732,19615732 0004,0007 HT SELENBP1 USP15 19615732 0007 HT SMAD4 USP15 21947082,22344298 0004,0004 LC CUL3 USP15 21145461 0004 HT CUL4B USP15 21145461 0004 HT KRT33B USP15 19615732,19615732 0004,0007 HT KRT81 USP15 19615732,19615732 0004,0007 HT USP10 USP15 22939629 0401 HT SART3 USP15 24984263,27060135,24526689,24526689,19615732 0004,0096,0096,0004,0004 LC,HT KRT31 USP15 19615732,19615732 0004,0007 HT SMAD2 USP15 21947082,26455393,22344298 0004,0004,0004 LC SMAD1 USP15 21947082,22344298 0004,0004 LC UGP2 USP15 22863883 0401 HT TMEM132A USP15 26496610,26496610 0007,0004 HT ZC3H13 USP15 22939629 0401 HT VSIG8 USP15 19615732,19615732 0004,0007 HT ATL3 USP15 26496610,26496610 0007,0004 HT MEPCE USP15 19615732,19615732 0004,0007 HT WAPL USP15 22939629 0401 HT FERMT3 USP15 26496610,26496610 0007,0004 HT CAND1 USP15 21145461 0004 HT LRRC15 USP15 19615732,19615732 0004,0007 HT PRPF31 USP15 19615732,19615732 0004,0007 HT KRT35 USP15 19615732,19615732 0004,0007 HT COPS5 USP15 21145461 0004 HT TCEAL4 USP15 26496610,26496610 0007,0004 HT SGTB USP15 26496610,26496610 0007,0004 HT EEF2KMT USP15 26186194 0004 HT SORT1 USP15 26496610,26496610 0007,0004 HT PHB2 USP15 17353931,17353931 0006,0004 HT NUSAP1 USP15 22863883 0401 HT Q9H368 USP15 17353931 0006 HT OBFC1 USP15 26186194 0004 HT TUT1 USP15 19615732,19615732 0004,0007 HT SMURF2 USP15 26435193,26435193,22344298 0004,0415,0004 LC MKNK2 USP15 26496610,26496610 0007,0004 HT TRPV5 USP15 26186194 0004 HT Q9P0T0 USP15 21947082,26455393,22344298,21947082,21947082 0004,0004,0004,0096,0415 LC HMG20B USP15 22939629 0401 HT ZMYM2 USP15 22939629 0401 HT MYH2 USP15 19615732,19615732 0004,0007 HT Q9UQS6 USP15 19738201 0004 HT LSM2 USP15 19615732,19615732 0004,0007 HT USP15 USP15 22001210,22001210,22001210,22001210 0096,0114,0071,0826 LC USP15 LSM4 19615732,19615732 0004,0007 HT USP15 MYH4 19615732,19615732 0004,0007 HT USP15 HEL-S-134P 19615732 0004 HT USP15 HEL-S-29 19615732 0004 HT USP15 HEL-S-87P 19615732 0004 HT PSMD11 USP15 19615732,19615732 0004,0007 HT DFFA USP15 17353931,17353931 0006,0004 HT PLOD2 USP15 22863883 0401 HT CFLAR USP15 17353931 0006 HT PRPF4 USP15 19615732,19615732 0004,0007 HT PRPF3 USP15 19615732,19615732 0004,0007 HT PPIH USP15 19615732,19615732 0004,0007 HT RNF40 USP15 19615732,19615732 0004,0007 HT KRT34 USP15 19615732,19615732 0004,0007 HT SNUPN USP15 26186194 0004 HT LSM8 USP15 19615732,19615732 0004,0007 HT FAM107A USP15 17353931 0006 HT ALDOA USP15 19615732 0007 HT CKB USP15 19615732 0007 HT FABP4 USP15 19615732,19615732 0004,0007 HT PGAM2 USP15 19615732,19615732 0004,0007 HT ME2 USP15 17353931 0006 HT CD40 USP15 17353931,17353931 0006,0004 HT CALML3 USP15 19615732,19615732 0004,0007 HT PSMB9 USP15 26186194 0004 HT SHC1 USP15 19380743 0004 HT ECHS1 USP15 26186194 0004 HT ADSL USP15 19615732,19615732 0004,0007 HT ID1 USP15 26496610,26496610 0007,0004 HT BAG6 USP15 26496610,26496610 0007,0004 HT LGALS7|LGALS7B USP15 19615732,19615732 0004,0007 HT PSMD7 USP15 19615732,26186194 0004,0004 HT USP11 USP15 19615732,19615732 0004,0007 HT PLK1 USP15 27173435 0676 HT BCAT1 USP15 26186194 0004 HT UBE2G2 USP15 17353931,17353931 0006,0004 HT LSM6 USP15 19615732,19615732 0004,0007 HT KRT85 USP15 19615732,19615732 0004,0007 HT CSTF1 USP15 19615732,19615732 0004,0007 HT SELENBP1 USP15 19615732 0007 HT CUL3 USP15 21145461 0004 HT CUL4B USP15 21145461 0004 HT KRT33B USP15 19615732,19615732 0004,0007 HT KRT81 USP15 19615732,19615732 0004,0007 HT USP10 USP15 22939629 0401 HT SART3 USP15 19615732 0004 HT KRT31 USP15 19615732,19615732 0004,0007 HT UGP2 USP15 22863883 0401 HT TMEM132A USP15 26496610,26496610 0007,0004 HT ZC3H13 USP15 22939629 0401 HT VSIG8 USP15 19615732,19615732 0004,0007 HT ATL3 USP15 26496610,26496610 0007,0004 HT MEPCE USP15 19615732,19615732 0004,0007 HT WAPL USP15 22939629 0401 HT FERMT3 USP15 26496610,26496610 0007,0004 HT CAND1 USP15 21145461 0004 HT LRRC15 USP15 19615732,19615732 0004,0007 HT PRPF31 USP15 19615732,19615732 0004,0007 HT KRT35 USP15 19615732,19615732 0004,0007 HT COPS5 USP15 21145461 0004 HT TCEAL4 USP15 26496610,26496610 0007,0004 HT SGTB USP15 26496610,26496610 0007,0004 HT EEF2KMT USP15 26186194 0004 HT SORT1 USP15 26496610,26496610 0007,0004 HT PHB2 USP15 17353931,17353931 0006,0004 HT NUSAP1 USP15 22863883 0401 HT Q9H368 USP15 17353931 0006 HT OBFC1 USP15 26186194 0004 HT TUT1 USP15 19615732,19615732 0004,0007 HT MKNK2 USP15 26496610,26496610 0007,0004 HT TRPV5 USP15 26186194 0004 HT HMG20B USP15 22939629 0401 HT ZMYM2 USP15 22939629 0401 HT MYH2 USP15 19615732,19615732 0004,0007 HT Q9UQS6 USP15 19738201 0004 HT LSM2 USP15 19615732,19615732 0004,0007 HT USP15 LSM4 19615732,19615732 0004,0007 HT USP15 MYH4 19615732,19615732 0004,0007 HT USP15 HEL-S-134P 19615732 0004 HT USP15 HEL-S-29 19615732 0004 HT USP15 HEL-S-87P 19615732 0004 HT RNF40 USP15 24526689 0004 LC TGFBR1 USP15 23973329,24850914,22344298 0004,0004,0004 LC SMAD4 USP15 21947082,22344298 0004,0004 LC SART3 USP15 24984263,27060135,24526689,24526689 0004,0096,0096,0004 LC SMAD2 USP15 21947082,26455393,22344298 0004,0004,0004 LC SMAD1 USP15 21947082,22344298 0004,0004 LC SMURF2 USP15 26435193,26435193,22344298 0004,0415,0004 LC Q9P0T0 USP15 21947082,26455393,22344298,21947082,21947082 0004,0004,0004,0096,0415 LC USP15 USP15 22001210,22001210,22001210,22001210 0096,0114,0071,0826 LC PLOD2 USP15 22863883 0401 LC FN1 USP15 19738201 0030 LC UBC USP15 25527291,22626734,19373254,20622874,24850914,21209336 0415,0415,0415,0415,0415,0998 LC,HT PLA2G2A USP15 22118674 0415 LC UCHL3 USP15 22626734 0415 HT TRIM21 USP15 23105109,25416956,25416956,25416956,25416956 0018,1112,0397,0018,1356 LC,HT BMPR1A USP15 24850914,24850914,24850914 0004,0415,0428 LC USP8 USP15 22626734 0415 HT USP14 USP15 22626734 0415 HT USP4 USP15 22626734 0415 HT TRIM25 USP15 24399297,24399297 0004,0415 LC USP10 USP15 22939629 0401 LC SART3 USP15 PDB_5JJW 0114 LC JOSD1 USP15 22626734 0415 HT UBE2S USP15 20622874 0415 LC HIST2H2BE USP15 24526689,24526689 0415,0004 LC UGP2 USP15 22863883 0401 LC CCDC57 USP15 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT ZC3H13 USP15 22939629 0401 LC YOD1 USP15 22626734 0415 HT USP51 USP15 22626734 0415 HT RNF144B USP15 23105109 0018 LC TRIM46 USP15 23105109 0018 LC BRAP USP15 23105109,23105109 0018,0004 LC WAPL USP15 22939629 0401 LC TRIM74 USP15 23105109 0018 LC USP33 USP15 22626734 0415 HT BAP1 USP15 22626734 0415 HT STAM USP15 22626734 0415 HT USP7 USP15 22626734 0415 HT TRIM63 USP15 22626734 0415 HT SPDL1 USP15 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT OTUB1 USP15 22626734 0415 HT SENP8 USP15 22626734 0415 HT USP28 USP15 22626734 0415 HT RNF126 USP15 23105109 0018 LC NUSAP1 USP15 22863883 0401 LC RBCK1 USP15 23105109 0018 LC TRIM54 USP15 22626734 0415 HT TRIM5 USP15 23105109 0018 LC CARD9 USP15 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT SENP3 USP15 22626734 0415 HT SMURF2 USP15 26435193,26435193 0004,0415 LC Q9NS08 USP15 23105109 0018 LC Q9P0T0 USP15 21947082,21947082,21947082 0004,0096,0415 LC HMG20B USP15 22939629 0401 LC ZMYM2 USP15 22939629 0401 LC USP21 USP15 22626734 0415 HT USP20 USP15 22626734 0415 HT USP15 USP15 PDB_3LMN,22001210,22001210,22001210,22001210 0114,0096,0114,0071,0826 LC USP15 TRAF6 20622874 0415 LC USP15 TRIM17 23105109 0018 LC USP15 MAD1L1 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT USP15 HEL-117 22626734 0415 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9Y4E8 P60604 USP15 UBE2G2 0.236 17353931 Q9Y4E8 O43172 USP15 PRPF4 0.332 19615732 Q9Y4E8 O15105 USP15 SMAD7 0.21 22344298 Q9Y4E8 O43541 USP15 SMAD6 0.376 24850914 Q9Y4E8 Q9HAU4 USP15 SMURF2 0.569 26435193,22344298 Q9Y4E8 Q9HCE7 USP15 SMURF1 0.126 23184937 Q9Y4E8 Q9H668 USP15 OBFC1 0.126 26186194 Q9Y4E8 Q9NPJ6 USP15 MED4 0.126 25281560 Q9Y4E8 Q9NQA5 USP15 TRPV5 0.126 26186194 Q9Y4E8 Q9H257 USP15 CARD9 0.454 25416956 Q9Y4E8 Q9H368 USP15 Q9H368 0.236 17353931 Q9Y6Y0 Q9Y4E8 IVNS1ABP USP15 0.126 unassigned1312 Q9Y577 Q9Y4E8 TRIM17 USP15 0.183 23105109 Q9Y4E8 P33991 USP15 MCM4 0.126 unassigned1312 Q9Y4E8 Q9UQ88 USP15 CDK11A 0.126 unassigned1312 Q9Y4E8 Q9UKN8 USP15 GTF3C4 0.126 unassigned1312 Q9Y4E8 Q9UBC2 USP15 EPS15L1 0.126 unassigned1312 Q9Y4E8 Q9BYM8 USP15 RBCK1 0.183 23105109 Q9Y4E8 Q7Z419 USP15 RNF144B 0.183 23105109 Q9Y4E8 Q16851 USP15 UGP2 0.081 22863883 Q9Y4E8 Q15796 USP15 SMAD2 0.507 21947082,26455393,22344298 Q9Y4E8 P40818 USP15 USP8 0.183 22626734 Q9Y4E8 P11274 USP15 BCR 0.126 unassigned1312 Q9Y4E8 P30291 USP15 WEE1 0.126 unassigned1312 Q9Y4E8 P25942 USP15 CD40 0.332 17353931 Q9Y4E8 O15519 USP15 CFLAR 0.126 17353931 Q9Y4E8 O00238 USP15 BMPR1B 0.21 24850914 Q9Y4E8 C4AM86 USP15 KRT35 0.126 19615732 Q9Y4E8 O15169 USP15 AXIN1 0.21 26884171 Q9Y4E8 O00469 USP15 PLOD2 0.081 22863883 Q9Y4E8 O00273 USP15 DFFA 0.332 17353931 Q9Y4E8 O60271 USP15 SPAG9 0.126 unassigned1312 Q9Y4E8 P23368 USP15 ME2 0.126 17353931 Q9Y4E8 O95990 USP15 FAM107A 0.236 17353931 Q9Y4E8 P09936 USP15 UCHL1 0.183 22626734 Q9Y4E8 P15374 USP15 UCHL3 0.183 22626734 Q9Y4E8 P14555 USP15 PLA2G2A 0.309 22118674 Q9Y4E8 P33993 USP15 MCM7 0.126 unassigned1312 Q9Y4E8 Q93009 USP15 USP7 0.183 22626734 Q9Y4E8 P54578 USP15 USP14 0.183 22626734 Q9Y4E8 P36897 USP15 TGFBR1 0.507 23973329,24850914,22344298 Q9Y4E8 P51784 USP15 USP11 0.126 19615732 Q9Y4E8 P49736 USP15 MCM2 0.126 unassigned1312 Q9Y4E8 Q92783 USP15 STAM 0.183 22626734 Q9Y4E8 Q15040 USP15 JOSD1 0.183 22626734 Q9Y4E8 Q04771 USP15 ACVR1 0.21 24850914 Q9Y4E8 Q14566 USP15 MCM6 0.126 unassigned1312 Q9Y4E8 Q92764 USP15 KRT35 0.126 19615732 Q9Y4E8 Q16763 USP15 UBE2S 0.309 20622874 Q9Y4E8 Q5T200 USP15 ZC3H13 0.081 22939629 Q9Y4E8 Q70EK9 USP15 USP51 0.183 22626734 Q9Y4E8 Q5VTR2 USP15 RNF20 0.21 24526689 Q9Y4E8 Q5VVQ6 USP15 YOD1 0.183 22626734 Q9Y4E8 Q92560 USP15 BAP1 0.183 22626734 Q9Y4E8 Q7Z5K2 USP15 WAPAL 0.081 22939629 Q9Y4E8 Q7Z569 USP15 BRAP 0.416 23105109 Q9Y4E8 Q7Z4K8 USP15 TRIM46 0.183 23105109 Q9Y4E8 Q86UV6 USP15 TRIM74 0.183 23105109 Q9Y4E8 Q8TEY7 USP15 USP33 0.183 22626734 Q9Y4E8 Q8WUA4 USP15 GTF3C2 0.126 unassigned1312 Q9Y4E8 Q9UBW7 USP15 ZMYM2 0.081 22939629 Q9Y4E8 Q9BXS6 USP15 NUSAP1 0.081 22863883 Q9Y4E8 Q96BY7 USP15 ATG2B 0.126 unassigned1312 Q9Y4E8 Q96LD8 USP15 SENP8 0.183 22626734 Q9Y4E8 Q96FW1 USP15 OTUB1 0.183 22626734 Q9Y4E8 Q9BWX1 USP15 PHF7 0.183 23105109 Q9Y4E8 Q9BV68 USP15 RNF126 0.183 23105109 Q9Y4E8 Q99623 USP15 PHB2 0.332 17353931 Q9Y4E8 Q9H1A4 USP15 ANAPC1 0.21 26884171 Q9Y4E8 Q9C035 USP15 TRIM5 0.183 23105109 Q9Y4E8 Q9H4L4 USP15 SENP3 0.183 22626734 Q9Y4E8 Q9NY27 USP15 PPP4R2 0.126 unassigned1312 Q9Y4E8 Q9Y2K6 USP15 USP20 0.183 22626734 Q9Y4E8 Q9Y297 USP15 BTRC 0.21 26884171 Q9Y4K3 Q9Y4E8 TRAF6 USP15 0.309 20622874 Q9Y4E8 P0CG48 USP15 UBC 0.876 16005295,25527291,20622874,22626734,19373254,24850914 Q9Y4E8 Q7Z6Z7 USP15 HUWE1 0.126 25147182 Q9Y4E8 Q6IN85 USP15 SMEK1 0.126 unassigned1312 Q9Y4E8 Q86VP6 USP15 CAND1 0.126 21145461 Q9Y4E8 O95149 USP15 SNUPN 0.126 26186194 Q9Y4E8 P02545 USP15 LMNA 0.126 22412018 Q9Y4E8 P04629 USP15 NTRK1 0.126 25921289 Q9Y4E8 P06748 USP15 NPM1 0.126 23402259 Q9Y4E8 Q9HBH9 USP15 MKNK2 0.236 26496610 Q9Y4Z0 Q9Y4E8 LSM4 USP15 0.236 19615732 Q9Y4E8 Q8IYF3 USP15 TEX11 0.236 unassigned1304 Q9Y4E8 Q7L2J0 USP15 MEPCE 0.236 19615732 Q9Y4E8 P78386 USP15 KRT85 0.236 19615732 Q9Y4E8 P47929 USP15 LGALS7B 0.236 19615732 Q9Y4E8 P04075 USP15 ALDOA 0.236 19615732 Q9Y4E8 O95777 USP15 LSM8 0.236 19615732 Q9Y4E8 A0A0C4DGS5 USP15 A0A0C4DGS5 0.236 unassigned1304 Q9Y4E8 P15090 USP15 FABP4 0.236 19615732 Q9Y4E8 P57678 USP15 GEMIN4 0.236 unassigned1304 Q9Y4E8 P30566 USP15 ADSL 0.236 19615732 Q9Y4E8 Q96EA4 USP15 SPDL1 0.454 25416956 Q9Y4E8 Q15323 USP15 KRT31 0.236 19615732 Q9Y4E8 O76011 USP15 KRT34 0.236 19615732 Q9Y4E8 P19474 USP15 TRIM21 0.554 25416956,23105109 Q9Y4E8 P15259 USP15 PGAM2 0.236 19615732 Q9Y4E8 Q14533 USP15 KRT81 0.236 19615732 Q9Y4E8 Q5VU13 USP15 VSIG8 0.236 19615732 Q9Y6D9 Q9Y4E8 MAD1L1 USP15 0.583 25416956,unassigned1304 Q9Y4E8 Q14525 USP15 KRT33B 0.236 19615732 Q9Y4E8 Q9Y333 USP15 LSM2 0.236 19615732 Q9Y4E8 Q8WWY3 USP15 PRPF31 0.236 19615732 Q9Y4E8 P62312 USP15 LSM6 0.236 19615732 Q9Y4E8 Q15020 USP15 SART3 0.794 24526689,19615732,24984263,27060135 Q9Y4E8 O00231 USP15 PSMD11 0.236 19615732 Q9Y4E8 P27482 USP15 CALML3 0.236 19615732 Q9Y4E8 Q9UKX2 USP15 MYH2 0.236 19615732 Q9Y4E8 Q05048 USP15 CSTF1 0.236 19615732 Q9Y4E8 O43395 USP15 PRPF3 0.236 19615732 Q9Y4E8 P84022 USP15 SMAD3 0.765 21947082,26455393,22344298 Q9Y623 Q9Y4E8 MYH4 USP15 0.236 19615732 Q9Y4E8 Q8TF66 USP15 LRRC15 0.236 19615732 Q9Y4E8 Q13228 USP15 SELENBP1 0.236 19615732 Q9Y4E8 P12277 USP15 CKB 0.236 19615732 Q9Y4E8 Q2TAC2 USP15 CCDC57 0.454 25416956 Q9Y4E8 O43447 USP15 PPIH 0.236 19615732 Q9Y4E8 Q9NYA3 USP15 GOLGA6A 0.236 unassigned1304 Q9Y4E8 Q9H6E5 USP15 TUT1 0.236 19615732 Q9Y4E8 P02751 USP15 FN1 0.236 19738201 Q9Y4E8 Q96EI5 USP15 TCEAL4 0.236 26496610 Q9Y4E8 Q96EQ0 USP15 SGTB 0.236 26496610 Q9Y4E8 Q99523 USP15 SORT1 0.236 26496610 Q9Y4E8 Q13485 USP15 SMAD4 0.376 21947082,22344298 Q9Y4E8 Q13489 USP15 BIRC3 0.236 23524849 Q9Y4E8 Q9BYT3 USP15 STK33 0.454 22451720 Q9Y4E8 Q13490 USP15 BIRC2 0.236 23524849 Q9Y4E8 Q15797 USP15 SMAD1 0.376 21947082,22344298 Q9Y4E8 Q24JP5 USP15 TMEM132A 0.236 26496610 Q9Y4E8 P83887 USP15 TUBG1 0.236 26496610 Q9Y4E8 Q6DD88 USP15 ATL3 0.236 26496610 Q9Y4E8 A0A087WUI6 USP15 PIBF1 {ECO:0000313|ENSEMBL:ENSP00000478697} 0.236 unassigned1304 Q9Y4E8 P46379 USP15 BAG6 0.236 26496610 Q9Y4E8 P53350 USP15 PLK1 0.236 27173435,unassigned1312 Q9Y4E8 Q86UX7 USP15 FERMT3 0.236 26496610 Q9Y4E8 P41134 USP15 ID1 0.236 26496610 Q9Y4E8 O95786 USP15 DDX58 0.454 26061460 Q9Y4E8 P60896 USP15 SHFM1 0.236 24811749 Q9Y4E8 O75150 USP15 RNF40 0.396 19615732,24526689 Q9Y4E8 P36894 USP15 BMPR1A 0.523 24850914 Q9Y4E8 Q9Y4E8 USP15 USP15 0.899 22001210 Q9Y4E8 P29353 USP15 SHC1 0.126 19380743 Q9Y4E8 Q92905 USP15 COPS5 0.126 21145461 Q9Y4E8 P30084 USP15 ECHS1 0.126 26186194 Q9Y4E8 Q969Q1 USP15 TRIM63 0.183 22626734 Q9Y4E8 P35222 USP15 CTNNB1 0.376 26884171 Q9Y4E8 P28065 USP15 PSMB9 0.126 26186194 Q9Y4E8 Q96G04 USP15 FAM86A 0.126 26186194 Q9Y4E8 Q9BUZ4 USP15 TRAF4 0.376 23973329 Q9Y4E8 Q96RU2 USP15 USP28 0.183 22626734 Q9Y4E8 Q9BYV2 USP15 TRIM54 0.183 22626734 Q9Y4E8 Q9P0W2 USP15 HMG20B 0.081 22939629 Q9Y4E8 Q9P260 USP15 KIAA1468 0.126 unassigned1312 Q9Y4E8 Q9UBU9 USP15 NXF1 0.126 22658674 Q9Y4E8 Q9UK80 USP15 USP21 0.332 22626734 Q9Y4E8 Q9UQE7 USP15 SMC3 0.126 unassigned1312 Q9Y4E8 P34947 USP15 GRK5 0.126 22952844 Q9Y4E8 P46531 USP15 NOTCH1 0.126 23022380 Q9Y4E8 C5E524 USP15 NS1 {ECO:0000313|EMBL:ACQ84472.1} 0.126 unassigned1333 Q9Y4E8 Q13618 USP15 CUL3 0.126 21145461 Q9Y4E8 Q13620 USP15 CUL4B 0.126 21145461 Q9Y4E8 A3KN83 USP15 SBNO1 0.126 unassigned1312 Q9Y4E8 P48431 USP15 SOX2 0.126 23667531 Q9Y4E8 Q13642 USP15 FHL1 0.454 21219870 Q9Y4E8 Q14258 USP15 TRIM25 0.569 24399297 Q9Y4E8 Q14683 USP15 SMC1A 0.126 unassigned1312 Q9Y4E8 Q14694 USP15 USP10 0.081 22939629 Q9Y4E8 Q14C86 USP15 GAPVD1 0.126 unassigned1312 Q9Y4E8 Q00613 USP15 HSF1 0.126 unassigned1312 Q9Y4E8 Q12955 USP15 ANK3 0.126 unassigned1312 Q9Y4E8 Q13107 USP15 USP4 0.354 22626734,22706160 Q9Y4E8 I6T1Z2 USP15 NS1 {ECO:0000313|EMBL:AFM71862.1} 0.126 unassigned1333 Q9Y4E8 P51665 USP15 PSMD7 0.236 19615732,26186194 Q9Y4E8 Q15554 USP15 TERF2 0.126 20811636 Q9Y4E8 Q01860 USP15 POU5F1 0.126 26687479 Q9Y4E8 Q06945 USP15 SOX4 0.126 unassigned1312 Q9Y4E8 Q2TBE6 USP15 PI4K2A 0.21 23146885 Q9Y4E8 P54687 USP15 BCAT1 0.126 26186194 Q9Y4E8 Q16777 USP15 HIST2H2AC 0.21 24526689 Q9Y4E8 Q16778 USP15 HIST2H2BE 0.454 24526689

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 PSMD11 USP15 MI:0045 experimental interaction detection MI:0461 interaction database BMPR1B USP15 MI:0045 experimental interaction detection MI:0461 interaction database DFFA USP15 MI:0045 experimental interaction detection MI:0461 interaction database SMAD7 USP15 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database CFLAR USP15 MI:0045 experimental interaction detection MI:0461 interaction database PRPF4 USP15 MI:0045 experimental interaction detection MI:0461 interaction database PRPF3 USP15 MI:0045 experimental interaction detection MI:0461 interaction database PPIH USP15 MI:0045 experimental interaction detection MI:0461 interaction database SMAD6 USP15 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H2BK USP15 MI:0362 inference MI:0461 interaction database RNF40 USP15 MI:0045 experimental interaction detection MI:0461 interaction database ULK1 USP15 MI:0362 inference MI:0461 interaction database DNAJB5 USP15 MI:0362 inference MI:0461 interaction database KRT34 USP15 MI:0045 experimental interaction detection MI:0461 interaction database SNUPN USP15 MI:0045 experimental interaction detection MI:0461 interaction database IKBKAP USP15 MI:0362 inference MI:0461 interaction database MOCS3 USP15 MI:0362 inference MI:0461 interaction database HSPA4L USP15 MI:0362 inference MI:0461 interaction database LSM8 USP15 MI:0045 experimental interaction detection MI:0461 interaction database DDX58 USP15 MI:0045 experimental interaction detection MI:0461 interaction database FAM107A USP15 MI:0045 experimental interaction detection MI:0461 interaction database TGFB1 USP15 MI:0362 inference MI:1106 pathways database LMNA USP15 MI:0045 experimental interaction detection MI:0461 interaction database FN1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database ALDOA USP15 MI:0045 experimental interaction detection MI:0461 interaction database NTRK1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database GNAI2 USP15 MI:0362 inference MI:0461 interaction database EIF2S1 USP15 MI:0362 inference MI:0461 interaction database NPM1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H2BJ USP15 MI:0362 inference MI:0461 interaction database UCHL1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database UBB USP15 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database UBC USP15 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database HSPA1A USP15 MI:0362 inference MI:0461 interaction database HSPA1B USP15 MI:0362 inference MI:0461 interaction database DLAT USP15 MI:0362 inference MI:0461 interaction database HSPA8 USP15 MI:0362 inference MI:0461 interaction database CKB USP15 MI:0045 experimental interaction detection MI:0461 interaction database PLA2G2A USP15 MI:0045 experimental interaction detection MI:0461 interaction database FABP4 USP15 MI:0045 experimental interaction detection MI:0461 interaction database PGAM2 USP15 MI:0045 experimental interaction detection MI:0461 interaction database UCHL3 USP15 MI:0045 experimental interaction detection MI:0461 interaction database CBR1 USP15 MI:0362 inference MI:0461 interaction database HSPA6 USP15 MI:0362 inference MI:0461 interaction database TRIM21 USP15 MI:0045 experimental interaction detection MI:0461 interaction database CSNK2A2 USP15 MI:0362 inference MI:0461 interaction database EIF2S2 USP15 MI:0362 inference MI:0461 interaction database FBL USP15 MI:0362 inference MI:0461 interaction database TUBG1 USP15 MI:0362 inference MI:0461 interaction database ME2 USP15 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H2BO USP15 MI:0362 inference MI:0461 interaction database CDK2 USP15 MI:0362 inference MI:0461 interaction database DNAJB1 USP15 MI:0362 inference MI:0461 interaction database CD40 USP15 MI:0045 experimental interaction detection MI:0461 interaction database DDX6 USP15 MI:0362 inference MI:0461 interaction database CALML3 USP15 MI:0045 experimental interaction detection MI:0461 interaction database PSMB9 USP15 MI:0045 experimental interaction detection MI:0461 interaction database SHC1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database ECHS1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database ADSL USP15 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H2BB USP15 MI:0362 inference MI:0461 interaction database HSPA1L USP15 MI:0362 inference MI:0461 interaction database HSPA4 USP15 MI:0362 inference MI:0461 interaction database GRK5 USP15 MI:0045 experimental interaction detection MI:0461 interaction database BMPR1A USP15 MI:0045 experimental interaction detection MI:0461 interaction database TGFBR1 USP15 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database TGFBR2 USP15 MI:0362 inference MI:1106 pathways database USP8 USP15 MI:0045 experimental interaction detection MI:0461 interaction database ID1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database HNF4A USP15 MI:0045 experimental interaction detection MI:0461 interaction database RANGAP1 USP15 MI:0362 inference MI:0461 interaction database BAG6 USP15 MI:0045 experimental interaction detection MI:0461 interaction database NOTCH1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database LGALS7 USP15 MI:0045 experimental interaction detection MI:0461 interaction database SOX2 USP15 MI:0045 experimental interaction detection MI:0461 interaction database CCT3 USP15 MI:0362 inference MI:0461 interaction database EIF2B2 USP15 MI:0362 inference MI:0461 interaction database PSMD7 USP15 MI:0045 experimental interaction detection MI:0461 interaction database USP11 USP15 MI:0045 experimental interaction detection MI:0461 interaction database PLK1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database USP14 USP15 MI:0045 experimental interaction detection MI:0461 interaction database HSPA2 USP15 MI:0362 inference MI:0461 interaction database BCAT1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database CSE1L USP15 MI:0362 inference MI:0461 interaction database SUMO3 USP15 MI:0362 inference MI:0461 interaction database RRP1 USP15 MI:0362 inference MI:0461 interaction database HIST1H2BD USP15 MI:0362 inference MI:0461 interaction database DNAJB13 USP15 MI:0362 inference MI:0461 interaction database UBE2G2 USP15 MI:0045 experimental interaction detection MI:0461 interaction database ACTB USP15 MI:0362 inference MI:0461 interaction database SHFM1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database SUMO2 USP15 MI:0362 inference MI:0461 interaction database LSM6 USP15 MI:0045 experimental interaction detection MI:0461 interaction database CNBP USP15 MI:0362 inference MI:0461 interaction database ACTA2 USP15 MI:0362 inference MI:0461 interaction database HIST1H4A USP15 MI:0362 inference MI:0461 interaction database HIST1H2BC USP15 MI:0362 inference MI:0461 interaction database RPS27A USP15 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database UBA52 USP15 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database SUMO1 USP15 MI:0362 inference MI:0461 interaction database ACTG1 USP15 MI:0362 inference MI:0461 interaction database ACTG2 USP15 MI:0362 inference MI:0461 interaction database CSNK2B USP15 MI:0362 inference MI:0461 interaction database ACTC1 USP15 MI:0362 inference MI:0461 interaction database ACTA1 USP15 MI:0362 inference MI:0461 interaction database CSNK2A1 USP15 MI:0362 inference MI:0461 interaction database KRT85 USP15 MI:0045 experimental interaction detection MI:0461 interaction database SMAD3 USP15 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database POU5F1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database ACVR1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database CSTF1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database NSUN2 USP15 MI:0362 inference MI:0461 interaction database NUP160 USP15 MI:0362 inference MI:0461 interaction database USP4 USP15 MI:0045 experimental interaction detection MI:0461 interaction database SELENBP1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database SMAD4 USP15 MI:0045 experimental interaction detection MI:0461 interaction database BIRC3 USP15 MI:0045 experimental interaction detection MI:0461 interaction database BIRC2 USP15 MI:0045 experimental interaction detection MI:0461 interaction database CUL3 USP15 MI:0045 experimental interaction detection MI:0461 interaction database CUL4B USP15 MI:0045 experimental interaction detection MI:0461 interaction database FHL1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database KEAP1 USP15 MI:0362 inference MI:1106 pathways database EIF2B1 USP15 MI:0362 inference MI:0461 interaction database TRIM25 USP15 MI:0045 experimental interaction detection MI:0461 interaction database KRT33B USP15 MI:0045 experimental interaction detection MI:0461 interaction database KRT81 USP15 MI:0045 experimental interaction detection MI:0461 interaction database RRP1B USP15 MI:0362 inference MI:0461 interaction database SART3 USP15 MI:0045 experimental interaction detection MI:0461 interaction database JOSD1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database KRT31 USP15 MI:0045 experimental interaction detection MI:0461 interaction database TERF2 USP15 MI:0045 experimental interaction detection MI:0461 interaction database SMAD2 USP15 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SMAD1 USP15 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database UBE2S USP15 MI:0045 experimental interaction detection MI:0461 interaction database HIST2H2AC USP15 MI:0045 experimental interaction detection MI:0461 interaction database HIST2H2BE USP15 MI:0045 experimental interaction detection MI:0461 interaction database TMEM132A USP15 MI:0045 experimental interaction detection MI:0461 interaction database CCDC57 USP15 MI:0045 experimental interaction detection MI:0461 interaction database HIST2H2BF USP15 MI:0362 inference MI:0461 interaction database RNF20 USP15 MI:0045 experimental interaction detection MI:0461 interaction database VSIG8 USP15 MI:0045 experimental interaction detection MI:0461 interaction database YOD1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database ATL3 USP15 MI:0045 experimental interaction detection MI:0461 interaction database SUMO4 USP15 MI:0362 inference MI:0461 interaction database USP51 USP15 MI:0045 experimental interaction detection MI:0461 interaction database MEPCE USP15 MI:0045 experimental interaction detection MI:0461 interaction database RNF144B USP15 MI:0045 experimental interaction detection MI:0461 interaction database TRIM46 USP15 MI:0045 experimental interaction detection MI:0461 interaction database BRAP USP15 MI:0045 experimental interaction detection MI:0461 interaction database HUWE1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database CTU1 USP15 MI:0362 inference MI:0461 interaction database TRIM74 USP15 MI:0045 experimental interaction detection MI:0461 interaction database FERMT3 USP15 MI:0045 experimental interaction detection MI:0461 interaction database CAND1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database ULK2 USP15 MI:0362 inference MI:0461 interaction database XRN1 USP15 MI:0362 inference MI:0461 interaction database HIST3H2BB USP15 MI:0362 inference MI:0461 interaction database SERBP1 USP15 MI:0362 inference MI:0461 interaction database USP33 USP15 MI:0045 experimental interaction detection MI:0461 interaction database LRRC15 USP15 MI:0045 experimental interaction detection MI:0461 interaction database ZCCHC13 USP15 MI:0362 inference MI:0461 interaction database PRPF31 USP15 MI:0045 experimental interaction detection MI:0461 interaction database GBF1 USP15 MI:0362 inference MI:0461 interaction database BAP1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database HSPH1 USP15 MI:0362 inference MI:0461 interaction database KRT35 USP15 MI:0045 experimental interaction detection MI:0461 interaction database STAM USP15 MI:0045 experimental interaction detection MI:0461 interaction database KAT2B USP15 MI:0362 inference MI:0461 interaction database COPS5 USP15 MI:0045 experimental interaction detection MI:0461 interaction database USP7 USP15 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H2BH USP15 MI:0362 inference MI:0461 interaction database TRIM63 USP15 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H2BA USP15 MI:0362 inference MI:0461 interaction database SPDL1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database TCEAL4 USP15 MI:0045 experimental interaction detection MI:0461 interaction database SGTB USP15 MI:0045 experimental interaction detection MI:0461 interaction database OTUB1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database EEF2KMT USP15 MI:0045 experimental interaction detection MI:0461 interaction database USP47 USP15 MI:0362 inference MI:0461 interaction database SENP8 USP15 MI:0045 experimental interaction detection MI:0461 interaction database USP28 USP15 MI:0045 experimental interaction detection MI:0461 interaction database SIN3A USP15 MI:0362 inference MI:0461 interaction database SORT1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H4G USP15 MI:0362 inference MI:0461 interaction database DNAJC2 USP15 MI:0362 inference MI:0461 interaction database PHB2 USP15 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H2BN USP15 MI:0362 inference MI:0461 interaction database HIST1H2BM USP15 MI:0362 inference MI:0461 interaction database HIST1H2BL USP15 MI:0362 inference MI:0461 interaction database URM1 USP15 MI:0362 inference MI:0461 interaction database PI4K2A USP15 MI:0362 inference MI:0461 interaction database TRAF4 USP15 MI:0045 experimental interaction detection MI:0461 interaction database RNF126 USP15 MI:0045 experimental interaction detection MI:0461 interaction database PHF7 USP15 MI:0045 experimental interaction detection MI:0461 interaction database RBCK1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database STK33 USP15 MI:0045 experimental interaction detection MI:0461 interaction database TRIM54 USP15 MI:0045 experimental interaction detection MI:0461 interaction database TRIM5 USP15 MI:0045 experimental interaction detection MI:0461 interaction database CARD9 USP15 MI:0045 experimental interaction detection MI:0461 interaction database SENP3 USP15 MI:0045 experimental interaction detection MI:0461 interaction database OBFC1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database TUT1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database SMURF2 USP15 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database MKNK2 USP15 MI:0045 experimental interaction detection MI:0461 interaction database SMURF1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database MED4 USP15 MI:0045 experimental interaction detection MI:0461 interaction database TRPV5 USP15 MI:0045 experimental interaction detection MI:0461 interaction database TUBG2 USP15 MI:0362 inference MI:0461 interaction database NXF1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database DNAJB4 USP15 MI:0362 inference MI:0461 interaction database EIF2B4 USP15 MI:0362 inference MI:0461 interaction database USP21 USP15 MI:0045 experimental interaction detection MI:0461 interaction database MYH2 USP15 MI:0045 experimental interaction detection MI:0461 interaction database USP22 USP15 MI:0362 inference MI:0461 interaction database RUVBL2 USP15 MI:0362 inference MI:0461 interaction database USP20 USP15 MI:0045 experimental interaction detection MI:0461 interaction database STXBP5L USP15 MI:0362 inference MI:0461 interaction database LSM2 USP15 MI:0045 experimental interaction detection MI:0461 interaction database USP15 TRAF6 MI:0045 experimental interaction detection MI:0461 interaction database USP15 LSM4 MI:0045 experimental interaction detection MI:0461 interaction database USP15 TRIM17 MI:0045 experimental interaction detection MI:0461 interaction database USP15 UCHL5 MI:0362 inference MI:1106 pathways database USP15 MYH4 MI:0045 experimental interaction detection MI:0461 interaction database USP15 MAD1L1 MI:0045 experimental interaction detection MI:0461 interaction database