PTM - CPLM Gene Name UniProt ID Type Position Code PRPF4; PRP4 O43172 Acetylation 27 K PRPF4; PRP4 O43172 Acetylation 53 K PRPF4; PRP4 O43172 Ubiquitination 159 K PRPF4; PRP4 O43172 Ubiquitination 284 K PRPF4; PRP4 O43172 Ubiquitination 200 K PRPF4; PRP4 O43172 Ubiquitination 45 K PRPF4; PRP4 O43172 Ubiquitination 147 K PRPF4; PRP4 O43172 Ubiquitination 216 K

PTM - dbPAF Gene Name UniProt ID Position Type Species PRPF4; PRP4 O43172 185 S Homo sapiens(Human) PRPF4; PRP4 O43172 236 Y Homo sapiens(Human) PRPF4; PRP4 O43172 240 S Homo sapiens(Human) PRPF4; PRP4 O43172 31 Y Homo sapiens(Human) PRPF4; PRP4 O43172 32 Y Homo sapiens(Human) PRPF4; PRP4 O43172 34 S Homo sapiens(Human) PRPF4; PRP4 O43172 483 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA O43172 K27-ac Acetylation LVAPVVKkPHIyyGs O43172 K53-ac Acetylation GESGILGkDGLKAGI O43172 K146-ac Acetylation VVGTDALkkTKKDDE O43172 K147-ac Acetylation VGTDALkkTKKDDEK O43172 K456-ac Acetylation QNLVTGVkFEPIHGN O43172 R345-m1 Methylation LGTTCYDrSWRLWDL O43172 Y31-p Phosphorylation VVKkPHIyyGsLEEK O43172 Y32-p Phosphorylation VKkPHIyyGsLEEKE O43172 S34-p Phosphorylation kPHIyyGsLEEKERE O43172 Y162-p Phosphorylation SKKSkEEyQQTWYHE O43172 S240-p Phosphorylation PISYCHFsPNSKMLA O43172 S483-p Phosphorylation IWTHPGWsPLKTLAG O43172 K15-sm Sumoylation STQATKTkAPDDLVA O43172 K27-sm Sumoylation LVAPVVKkPHIyyGs O43172 K45-sm Sumoylation KERERLAkGESGILG O43172 K159-sm Sumoylation DEKSKKSkEEyQQTW O43172 K159-ub Ubiquitination DEKSKKSkEEyQQTW

PTM - dbPTM UniProt ID Position Code Type Resources References O43172 27 K Acetylation Swiss-Prot 1010711 19608861 O43172 159 K Ubiquitylation Phosphositeplus.1010730 21890473 O43172 27 K Acetylation Phosphositeplus.1010730 19608861 O43172 483 S Phosphorylation Phosphositeplus.1010730 20068231;22115753 O43172 27 K Acetylation HPRD 9.0 19608861 O43172 483 S Phosphorylation HPRD 9.0 20068231

PTM - HPRD Symbol Position Code Type References PRPF4 27 K Acetylation 19608861 PRPF4 483 S Phosphorylation 20068231

PTM - UniProt UniProt ID Position Type PMIDs O43172 27 N6-acetyllysine 19608861

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type PRPF4 IPI00150269 K 27 VAPVVKaKPHIYYG acetylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 9128 114576 - K Ubiquitination 21139048 9128 114576 - K Ubiquitination 21890473 9128 114576 - K Ubiquitination 24654937 9128 114576 - K Neddylation 24654937 9128 114576 - K Sumoylation 24654937

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID PRPF4 Homo sapiens (Human) 158 "158,EKSKKSKEEYQQT" 158:21890473 PRPF4 Homo sapiens (Human) 159 "159,EKSKKSKEEYQQT" 159:21890473 PRPF4 Homo sapiens (Human) 159 "159,EKSKKSKEEYQQT" 159:21890473 PRPF4 Homo sapiens (Human) 158 "158,EKSKKSKEEYQQT" 158:21890473 PRPF4 Homo sapiens (Human) 159 "159,EKSKKSKEEYQQT" 159:21890473 PRPF4 Homo sapiens (Human) 159 "159,EKSKKSKEEYQQT" 159:21890473